Inhibition of aflatoxin B1 genotoxicity in human liver-derived HepG2 cells by kolaviron biflavonoids and molecular mechanisms of action

European Journal of Cancer Prevention

Volumn 9, Issue 5, 2000, Pages 351-361

  Nwankwo, J O ^a   Tahnteng, J G ^b   Emerole, G O ^b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IBADAN   (Nigeria)

Author keywords

Aflatoxin B1; Chemoprevention; Cytochrome P450 3A4; Genotoxicity; Glutathione S transferases; HepG2; Kolaviron

Indexed keywords

AFLATOXIN B1; BIFLAVONOID; BUTYLATED HYDROXYANISOLE; CYTOCHROME P450 3A4; GLUTATHIONE TRANSFERASE; HYDROGEN PEROXIDE; KOLAVIRON; REACTIVE OXYGEN METABOLITE; THYMIDINE DERIVATIVE; TROLOX C;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL STRAIN HEPG2; CHEMICAL STRUCTURE; CHEMOPROPHYLAXIS; CLONOGENIC ASSAY; COMPARATIVE STUDY; CYTOTOXICITY; DNA SYNTHESIS; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; GENETIC TRANSCRIPTION; GENOTOXICITY; LIVER CARCINOGENESIS; MOLECULAR DYNAMICS; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

AFLATOXIN B1; BLOTTING, NORTHERN; BLOTTING, WESTERN; BUTYLATED HYDROXYANISOLE; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; FLAVONOIDS; GLUTATHIONE TRANSFERASE; HUMANS; LIVER; MUTAGENS; PLANT EXTRACTS; PLANTS, MEDICINAL; POLYMERASE CHAIN REACTION; THYMIDINE;

EID: 0033734980     PISSN: 09598278     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008469-200010000-00010     Document Type: Article

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