Site-specific arylation of rat glutathione S-transferase A1 and A2 by bromobenzene metabolites in vivo

Chemical Research in Toxicology

Volumn 19, Issue 11, 2006, Pages 1426-1434

  Koen, Yakov M ^a   Yue, Weimin ^a   Galeva, Nadezhda A ^a   Williams, Todd D ^a   Hanzlik, Robert P ^a,b  

^a UNIVERSITY OF KANSAS   (United States)

^b 4048 Malott   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGAROSE; BENZENE DERIVATIVE; BENZOQUINONE DERIVATIVE; BROMOBENZENE; CARBON 14; CELL PROTEIN; CYSTEINE DERIVATIVE; EPOXIDE; GLUTATHIONE S TRANSFERASE A2; GLUTATHIONE S TRANSFERASE A3; GLUTATHIONE S TRANSFERASE M2; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE ALPHA; GLUTATHIONE TRANSFERASE M1; HISTIDINE DERIVATIVE; LIVER PROTEIN; LYSINE DERIVATIVE; PEPTIDE DERIVATIVE; QUINONE DERIVATIVE; UNCLASSIFIED DRUG;

ACCURACY; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARYLATION; COVALENT BOND; ELECTROSPRAY MASS SPECTROMETRY; ENZYME SUBUNIT; IN VIVO STUDY; LINEAR ION TRAP QUADRUPOLE FOURIER TRANSFORM MASS SPECTROMETRY; LIVER CYTOSOL; LIVER TOXICITY; MALE; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; METABOLITE; NONHUMAN; PEPTIDE MAPPING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN ISOLATION; PROTEIN TARGETING; PROTEOMICS; RADIOACTIVITY; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BROMOBENZENES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLUTATHIONE TRANSFERASE; ISOENZYMES; LIVER; MALE; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 33845254825     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx060142s     Document Type: Article

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