Accumulation of γ-globin mRNA and induction of irreversible erythroid differentiation after treatment of CML cell line K562 with new doxorubicin derivatives

Biochemical Pharmacology

Volumn 73, Issue 2, 2007, Pages 175-184

  Szulawska, Agata ^a   Arkusinska, Justyna ^a   Czyz, Malgorzata ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

Anthracycline derivatives; Differentiation; Erythroid gene expression; Growth arrest; K562; mRNA stabilization

Indexed keywords

ANTHRACYCLINE DERIVATIVE; BETA GLOBIN; DOXORUBICIN; DOXORUBICIN DERIVATIVE; EPIRUBICIN; GLOBIN MESSENGER RNA; HEMOGLOBIN; HEXAMETHYLENEIMINE DERIVATIVE; MESSENGER RNA; MORPHOLINE DERIVATIVE; TRANSCRIPTION FACTOR GATA 1;

ARTICLE; BETA THALASSEMIA; BIOACCUMULATION; CELL ACTIVITY; CELL DIFFERENTIATION; CELL GROWTH; CELL LEVEL; CELL LINE; CELL PROLIFERATION; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG SYNTHESIS; ERYTHROID CELL; GENE CONTROL; GENE INDUCTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; BASE SEQUENCE; CELL DIFFERENTIATION; DNA PRIMERS; DOXORUBICIN; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FLOW CYTOMETRY; GATA1 TRANSCRIPTION FACTOR; GLOBINS; HUMANS; K562 CELLS; LEUKEMIA, MYELOID, CHRONIC; PROTEIN BINDING; RNA, MESSENGER;

EID: 33845227815     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2006.09.028     Document Type: Article

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