The effect of chronic progressive nephropathy on the incidence of renal tubule cell neoplasms in control male F344 rats

Toxicologic Pathology

Volumn 30, Issue 6, 2002, Pages 681-686

  Seely, John C ^a   Haseman, Joseph K ^b   Nyska, Abraham ^b   Wolf, Douglas C ^c   Everitt, Jeffrey I ^d   Hailey, James R ^b  

^a EXPERIMENTAL PATHOLOGY LABORATORIES INC   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^d CIIT CENTERS FOR HEALTH RESEARCH   (United States)

Author keywords

Fischer 344 rat; Kidney; Males; National Toxicology Program; Neoplasia; Nephropathy

Indexed keywords

2 CHLOROBENZYLIDENEMALONONITRILE; 4 CHLOROPHENOL; ACETONITRILE; ANTHRAQUINONE DERIVATIVE; BROMOFORM; COUMARIN; DRONABINOL; EUGENOL; ISOBUTYL NITRITE; MANGANESE SULFATE; OCHRATOXIN; OZONE; PARACETAMOL; PHENOL DERIVATIVE; PHOSPHORIC ACID TRIS(2 CHLOROETHYL) ESTER; PHTHALIC ACID; PROMETHAZINE; PYRIDINE; QUINOLINE DERIVATIVE; ROXARSONE; SAFFLOWER OIL; SCOPOLAMINE BROMIDE; SODIUM AZIDE; TERT BUTYL ALCOHOL; TITANOCENE DICHLORIDE; XENOBIOTIC AGENT; XYLENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BIOASSAY; CANCER INCIDENCE; CHRONIC PROGRESSIVE NEPHROPATHY; CONFERENCE PAPER; CONTROLLED STUDY; GLOMERULOPATHY; KIDNEY DISEASE; KIDNEY FIBROSIS; KIDNEY TUBULE EPITHELIUM; KIDNEY TUMOR; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENOMA; ANIMALS; CARCINOMA; DISEASE PROGRESSION; EPITHELIAL CELLS; KIDNEY FAILURE, CHRONIC; KIDNEY NEOPLASMS; KIDNEY TUBULES; MALE; MICROTOMY; NATIONAL INSTITUTES OF HEALTH (U.S.); RATS; RATS, INBRED F344; RETROSPECTIVE STUDIES; UNITED STATES;

ANIMALIA; CARTHAMUS TINCTORIUS;

EID: 0036865804     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230290166779     Document Type: Conference Paper

References (39)

1. Gray JE (1977). Chronic progressive nephrosis in the albino rat. Crit Rev Toxicol 5: 115-144.
2. Montgomery CA, Seely JC (1990). Kidney. In: Pathology of the Fischer Rat: Reference and Atlas, Boorman GA, Eustis SL, Elwell MR, Montgomery CA, MacKenzie WF (eds). Academic Press, Inc, San Diego, CA, pp 127-153.
3. Short BG, Goldstein RS (1992). Nonneoplastic lesions in the kidney. In: Pathology of the Aging Rat, Mohr U, Dungworth DL, Capen CC (eds). ILSI Press, Washington, DC, pp 211-225.
4. Barthold SW (1998). Chronic progressive nephropathy, Rat. In: Urinary System, 2nd Ed., Jones TC, Hard GC, Mohr U (eds). Springer-Verlag, Berlin Heidelberg, pp 228-233.
5. Abrass CK (2000). The nature of chronic progressive nephropathy in aging rats. Adv Ren Replace Ther 7: 4-10.
6. Rao GN, Edmondson J, Elwell MR (1993). Influence of dietary protein concentration on severity of nephropathy in Fischer 344 rats. Toxicol Pathol 21: 353-361.
7. Gumprecht LA, Long CR, Soper KA, Smith PF, Haschek-Hock WM, Keenan KP (1993). The early effects of dietary restriction on the pathogenesis of chronic renal disease in Sprague-Dawley rats at 12 months. Toxicol Pathol 21: 528-537.
8. Hard GC, Alden CL (1992). Susceptibility of the kidney to toxic substances. In: Pathobiology of the Aging Rat, Mohr U, Dungworth DL, Capen CL (eds). ILSI Press, Washington, DC, pp 241-257.
9. Robertson JL (1998). Chemically induced glomerular injury: A review of basic mechanisms and specific xenobiotics. Toxicol Pathol 26: 64-72.
10. Brenner BM, Meyer TW, Hostetter TH (1983). Dietary protein intake and the progressive nature of kidney disease. N Engl J Med 307: 652-672.
11. Fogo A, Ichikawa I (1989). Evidence for the central role of glomerular growth promoters in the development of sclerosis. Sem Nephrol 9: 329-342.
12. Short BG (1993). Cell proliferation and renal carcinogenesis. Environ Health Perspect 101(Suppl 5): 115-120.
13. Hard GC (1998). Mechanisms of chemically induced renal carcinogenesis in the laboratory rodent. Toxicol Pathol 26: 104-112.
14. Khan KNM, Alden CL (2002). Kidney. In: Handbook of Toxicologic Pathology, 2nd Ed., Haschek WM, Rousseaux CG, Wallig MA (eds). Academic Press, San Diego, pp 255-336.
15. Konishi N, Ward JM (1989). Increased levels of DNA synthesis in hyperplastic renal tubules of aging nephropathy in female F344/NCR rats. Vet Pathol 26: 6-10.
16. Ward JM, Weghorst BA, Diwan BA, Konishi N, Lubet RA, Henneman JR, Devoz DE (1991). Evaluation of cell proliferation in the kidney of rodents with bromodeoxyuridine immunohistochemistry or tritriated thymidine autoradiography after exposure to renal toxins, tumor promoters and carcinogens. Prog Clin Biol Res 336: 369-388.
17. English JC, Perry LG, Vlaovic M, Moyer C, O'Donoghue JL (1994). Measurement of cell proliferation in the kidneys of Fischer 344 and SpragueDawley rats after gavage administration of hydroquinone. Fundam Appl Toxicol 23: 397-406.
18. Hard GC, Whysner J, English JC, Zang E, Williams GM (1997). Relationship of hydroquinone-associated rat renal tumors with spontaneous chronic progressive nephropathy. Toxicol Pathol 25: 132-143.
19. Hard GC, Rodgers IS, Baetcke KP, Richards WL, McGaughy RE, Valcovic LR (1993). Hazard evaluation of chemicals that cause accumulation of alpha2u-globulin, hyaline droplet nephropathy, and tubule neoplasia in the kidneys of male rats. Environ Health Perspect 99: 313-349.
20. Hard GC, Boorman GA, Wolf DC (2000). Re-evaluation of the 2-year chloroform drinking water carcinogenicity bioassay in Osborne-Mendel rats supports renal tubule injury as the mode of action underlying the renal tumor response. Toxicol Sci 53: 237-244.
21. Konishi N, Hiasa Y (1994). Renal carcinogenesis. In: Carcinogenesis, Waalkes MD, Ward JM (eds). Raven Press, New York, pp 123-159.
22. Barrett JC, Huff J (1991). Cellular and molecular mechanisms of chemically induced renal carcinogenesis. Renal Failure 13: 211-225.
23. Huff JC (1995). Mechanisms, chemical carcinogenesis, and risk assessment: Cell proliferation and cancer. Am J Ind Med 27: 293-300.
24. Marsman DS, Grumbein SL, Haseman JK, Hailey JR (1995). Chronic nephropathy and renal carcinogenicity of o-benzyl-p-chlorophenol in F344/N rats and B6C3F1 mice. Fundam Appl Toxicol 27: 252-262.
25. Hard GC, Neal GE (1992). Sequential study of the chronic nephrotoxicity induced by dietary administration of ethoxyguin in Fischer 344 rats. Fundam Appl Toxicol 18: 278-287.
26. Tsuda H, Krieg K (1992). Neoplastic lesions in the kidney. In: Pathobiology of the Aging Rat, Mohr U, Dungworth DL, Capen CL (eds). ILSI Press, Washington, DC, pp 227-240.
27. Haseman JK, Hailey JR, Morris RW (1998). Spontaneous neoplasm incidences in Fischer 344 Rats and B6C3F1 mice in two-year carcinogenicity studies: A national toxicology program update. Toxicol Pathol 26: 428-441.
28. Zwicker GM, Eyster RC, Sells DM, Gass JH (1992). Spontaneous renal neoplasms in aged Crl:CD BR rats. Toxicol Pathol 20: 125-130.
29. National Toxicology Program (2002). Chemicals associated with sitespecific tumor induction in kidney tubular cell. Toxicology Data Management System Database http://ntp-server. niehs.nih.gov/htdocs/sites/psite_cnt. html. http://dobby.niehs.nih.gov/postpwg/devl/openc.cfm.
30. Ward JM, Hardisty JF, Hailey JR, Street CS (1995). Peer review in toxicologic pathology. Toxicol Pathol 23: 226-234.
31. Shackelford C, Long G, Wolf J, Okerberg C, Herbert R (2002). Qualitative and quantitative analysis of nonneoplastic lesions in toxicology studies. Toxicol Pathol 30: 93-96.
32. Eustis SL, Hailey JR, Boorman GA, Haseman JK (1994). The utility of multiple-section sampling in the histopathological evaluation of the kidney for carcinogenicity studies. Toxicol Pathol 22: 457-472.
33. Siegel S (1956). Nonparametric Statistics for the Behavioral Sciences. McGraw Hill, New York, pp 75-83.
34. Cohen SM, Ellwein LB (1990). Cell proliferation in carcinogenesis. Science 249: 1007-1011.
35. Cardani R, Zavanella T (2000). Age-related cell proliferation and apoptosis in the kidney of male Fischer 344 rats with observations on a spontaneous tubular cell adenoma. Toxicol Pathol 28: 802-806.
36. Thurman JD, Hailey JR, Turturro A, Gaylor DW (1995). Spontaneous renal tubular carcinoma in Fischer-344 rat littermates. Vet Pathol 32: 419-422.
37. Hard GC, Long PH, Crissman JW, Everitt JI, Yano BL, Bertram TA (1994). Atypical tubule hyperplasia and renal tubule tumors in conventional rats in 90-day toxicity studies. Toxicol Pathol 22: 489-496.
38. Rao GN (1996). New diet (NTP-2000) for rats in the National Toxicology Programs toxicity and carcinogenicity studies. Fundam Appl Toxicol 32: 102-108.
39. Rao GN, Morris RW, Seely JC (2001). Beneficial effects of NTP-2000 diet on growth, survival and kidney and heart diseases of rats in chronic studies. Toxicol Sci 63: 245-255.