Identification and characterization of a human monoclonal antagonistic antibody AL-57 that preferentially binds the high-affinity form of lymphocyte function-associated antigen-1

Journal of Leukocyte Biology

Volumn 80, Issue 4, 2006, Pages 905-914

  Huang, Lili ^a   Shimaoka, Motomu ^b   Rondon, Isaac J ^a,c   Roy, Illa ^a   Chang, Qing ^a   Po, Melody ^a,d   Dransfield, Daniel T ^a   Ladner, Robert C ^a   Edge, Albert S B ^a,e   Salas, Azucena ^b   Wood, Clive R ^a   Springer, Timothy A ^b   Cohen, Edward H ^a  

^a Dyax Corp   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Catalyst Biosciences   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

Author keywords

Cell adhesion; I domain; ICAM 1; Integrin; Phage display

Indexed keywords

IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MAGNESIUM; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY AL 57;

ARTICLE; CELL ADHESION; CELL PROLIFERATION; CONTROLLED STUDY; FLUORESCENCE; HUMAN; HUMAN CELL; KERATINOCYTE; LYMPHOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL;

ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY REACTIONS; BINDING SITES; CELL ADHESION; CELL LINE; CELL PROLIFERATION; HUMANS; IMMUNOGLOBULIN G; INTERCELLULAR ADHESION MOLECULE-1; KERATINOCYTES; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MOLECULAR SEQUENCE DATA; PHYTOHEMAGGLUTININS; STRUCTURE-ACTIVITY RELATIONSHIP;

MURINAE;

EID: 33751523248     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1105649     Document Type: Article

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