The cataract-causing mutation G98R in human αA-crystallin leads to folding defects and loss of chaperone activity

Molecular Vision

Volumn 12, Issue , 2006, Pages 1372-1379

  Singh, Devendra ^a   Raman, Bakthisaran ^a   Ramakrishna, Tangirala ^a   Rao, Ch Mohan ^a  

^a CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CRYSTALLIN; ARGININE; CHAPERONE; GLYCINE; INSULIN; UREA;

ANIMAL CELL; ARTICLE; CATARACT; CELL INCLUSION; CIRCULAR DICHROISM; CONTROLLED STUDY; ESCHERICHIA COLI; FLUORESCENCE SPECTROSCOPY; GEL FILTRATION CHROMATOGRAPHY; GENE EXPRESSION; GENE MUTATION; GENE STRUCTURE; HUMAN; HUMAN CELL; LIGHT SCATTERING; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS; THERMOSTABILITY; TURBIDITY; WILD TYPE;

ALPHA-CRYSTALLIN A CHAIN; ARGININE; CATARACT; CIRCULAR DICHROISM; ESCHERICHIA COLI; GLYCINE; HUMANS; INCLUSION BODIES; MOLECULAR CHAPERONES; MUTATION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; UREA;

EID: 33751518175     PISSN: 10900535     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

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