Region-specific regulation of inflammation and pathogenesis in experimental autoimmune encephalomyelitis

Journal of Neuroimmunology

Volumn 181, Issue 1-2, 2006, Pages 122-132

  Archambault, Angela S ^a   Sim, Julia ^a   McCandless, Erin E ^a   Klein, Robyn S ^a   Russell, John H ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cerebellum; Chemokines; Experimental autoimmune encephalomyelitis; T cells; VCAM 1

Indexed keywords

CD11B ANTIGEN; CHEMOKINE; CHEMOKINE CXCL2; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; VASCULAR CELL ADHESION MOLECULE 1;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN REGION; CELL INFILTRATION; CEREBELLUM; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEMYELINATION; IMMUNOPATHOGENESIS; IMMUNOREGULATION; INFLAMMATION; INFLAMMATORY INFILTRATE; MACROPHAGE; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PARENCHYMA; PRIORITY JOURNAL; PROTEIN INDUCTION; SPINAL CORD; T LYMPHOCYTE; TH1 CELL; WHITE MATTER;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, CD11B; ANTIGENS, THY-1; CELL MOVEMENT; CEREBELLUM; CHEMOKINES; COLORING AGENTS; DEMYELINATING DISEASES; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENDOTHELIAL CELLS; MACROPHAGES; MICE; MICE, CONGENIC; MICE, INBRED C57BL; MONOCYTES; MYELIN-ASSOCIATED GLYCOPROTEIN; NERVE FIBERS, MYELINATED; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; SPINAL CORD; T-LYMPHOCYTES; TOLONIUM CHLORIDE; VASCULAR CELL ADHESION MOLECULE-1;

EID: 33751515069     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2006.08.012     Document Type: Article

References (45)

1. Abrams S.I., and Russell J.H. CD4+ T lymphocyte-induced target cell detachment. A model for T cell-mediated lytic and nonlytic inflammatory processes. J. Immunol. 146 (1991) 405-413
2. Abromson-Leeman S., Bronson R., Luo Y., Berman M., Leeman R., Leeman J., and Dorf M. T-cell properties determine disease site, clinical presentation, and cellular pathology of experimental autoimmune encephalomyelitis. Am. J. Pathol. 165 (2004) 1519-1533
3. Ando D.G., Clayton J., Kono D., Urban J.L., and Sercarz E.E. Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype. Cell. Immunol. 124 (1989) 132-143
4. Archambault A.S., Sim J., Gimenez M.T., and Russell J.H. Defining antigen-dependent stages of T cell migration from the blood to the central nervous system parenchyma. Eur. J. Immunol. 35 (2005) 1076-1085
5. Asensio V.C., Lassmann S., Pagenstecher A., Steffensen S.C., Henriksen S.J., and Campbell I.L. C10 is a novel chemokine expressed in experimental inflammatory demyelinating disorders that promotes recruitment of macrophages to the central nervous system. Am. J. Pathol. 154 (1999) 1181-1191
6. Bauer J., Huitinga I., Zhao W., Lassmann H., Hickey W.F., and Dijkstra C.D. The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis. Glia 15 (1995) 437-446
7. Bell M.D., Taub D.D., Kunkel S.J., Strieter R.M., Foley R., Gauldie J., and Perry V.H. Recombinant human adenovirus with rat MIP-2 gene insertion causes prolonged PMN recruitment to the murine brain. Eur. J. Neurosci. 8 (1996) 1803-1811
8. Bernard C.C., and Carnegie P.R. Experimental autoimmune encephalomyelitis in mice: immunologic response to mouse spinal cord and myelin basic proteins. J. Immunol. 114 (1975) 1537
9. Brosnan C.F., Bornstein M.B., and Bloom B.R. The effects of macrophage depletion on the clinical and pathologic expression of experimental allergic encephalomyelitis. J. Immunol. (Baltimore, Md.: 1950) 126 (1981) 614-620
10. Cohen J.A., Essayan D.M., Zweiman B., and Lisak R.P. Limiting dilution analysis of the frequency of antigen-reactive lymphocytes isolated from the central nervous system of Lewis rats with experimental allergic encephalomyelitis. Cell. Immunol. 108 (1987) 203-213
11. Cross A.H., T.O.M., and Raine C.S. Chronologic localization of myelin-reactive cells in the lesions of relapsing EAE: implications for the study of multiple sclerosis. Neurology 43 (1993) 1028-1033
12. Endoh M., Tabira T., Kunishita T., Sakai K., Yamamura T., and Taketomi T. DM-20, a proteolipid apoprotein, is an encephalitogen of acute and relapsing autoimmune encephalomyelitis in mice. J. Immunol. 137 (1986) 3832-3835
13. Gimenez M.A.T., Sim J.E., and Russell J.H. TNFR1-dependent VCAM-1 expression by astrocytes exposes the CNS to destructive inflammation. J. Neuroimmunol. 151 (2004) 116-125
14. Gimenez M.A., Sim J., Archambault A.S., Klein R.S., and Russell J.H. A Tumor Necrosis Factor Receptor 1-Dependent Conversation between Central Nervous System-Specific T Cells and the Central Nervous System Is Required for Inflammatory Infiltration of the Spinal Cord. Am. J. Pathol. 168 (2006) 1200-1209
15. Glabinski A.R., Tani M., Tuohy V.K., Tuthill R.J., and Ransohoff R.M. Central nervous system chemokine mRNA accumulation follows initial leukocyte entry at the onset of acute murine experimental autoimmune encephalomyelitis. Brain Behav. Immun. 9 (1995) 315-330
16. Glabinski A.R., Tani M., Strieter R.M., Tuohy V.K., and Ransohoff R.M. Synchronous synthesis of a- and b-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis. Am. J. Pathol. 150 (1997) 617-630
17. Glabinski A.R., Tuohy V.K., and Ransohoff R.M. Expression of chemokines RANTES, MIP-1alpha and GRO-alpha correlates with inflammation in acute experimental autoimmune encephalomyelitis. Neuroimmunomodulation 5 (1998) 166-171
18. Godiska R., Chantry D., Dietsch G.N., and Gray P.W. Chemokine expression in murine experimental allergic encephalomyelitis. J. Neuroimmunol. 58 (1995) 167-176
19. Graesser D., Mahooti S., and Madri J.A. Distinct roles for matrix metalloproteinase-2 and [alpha]4 integrin in autoimmune T cell extravasation and residency in brain parenchyma during experimental autoimmune encephalomyelitis. J. Neuroimmunol. 109 (2000) 121-131
20. Hayashi M., Luo Y., Laning J., Strieter R.M., and Dorf M.E. Production and function of moncyte chemoattractant protein-1 and other b-chemokines in murine glial cells. J. Neuroimmunol. 60 (1995) 143-150
21. Huitinga I., Ruuls S.R., Jung S., Van Rooijen N., Hartung H.-P., and Dijkstra C.D. Macrophages in T cell line-mediated, demyelinating, and chronic relapsing experimental autoimmune encephalomyelitis in Lewis rats. Clin. Exp. Immunol. 100 (1995) 344-351
22. Hulkower K., Brosnan C.F., and Aquino D.A. Expression of CSF-1, c-fms, and MCP-1 in the central nervous system of rats with experimental allergic encephalomyelitis. J. Immunol. 150 (1993) 2525-2533
23. Huseby E.S., Liggitt D., Brabb T., Schnabel B., Ohlen C., and Goverman J. A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis. J. Exp. Med. 194 (2001) 669-676
24. Irani D.N., and Griffin D.E. Isolation of brain parenchymal lymphocytes for flow cytometric analysis. Application to acute viral encephalitis. J. Immunol. Methods 139 (1991) 223-231
25. Karpus W.J., and Ransohoff R.M. Chemokine regulation of experimental autoimmune encephalomyelitis: temporal and spatial expression patterns govern disease pathogenesis. J. Immunol. 161 (1998) 2667-2671
26. Karpus W.J., Lukacs N.W., McRae B.L., Strieter R.M., Kunkel S.L., and Miller S.D. An important role for the chemokine macrophage inflammatory protein-1a in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis. J. Immunol. 155 (1995) 5003-5010
27. Kennedy K.J., Strieter R.M., Kunkel S.L., Lukacs N.W., and Karpus W.J. Acute and relapsing experimental autoimmune encephalomyelitis are regulated by differential expression of the CC chemokines macrophage inflammatory protein-1a and monocyte chemotactic protein-1. J. Neuroimmunol. 92 (1998) 98-108
28. Kuchroo V.K., Martin C.A., Greer J.M., Ju S.T., Sobel R.A., and Dorf M.E. Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis. J. Immunol. 151 (1993) 4371-4382
29. Lucchinetti C.F., Bruck W., Rodriguez M., and Lassmann H. Distinct patterns of multiple sclerosis pathology indicates heterogeneity on pathogenesis. Brain Pathol. 6 (1996) 259-274
30. Matejuk A., Dwyer J., Atsushi I., Bruender Z., Vandenbark A.A., and Offner H. Effects of cytokine deficiency on chemokine expression in CNS of mice with EAE. J. Neurosci. Res. 67 (2002) 680-688
31. McManus C.M., Brosnan C.F., and Berman J.W. Cytokine Induction of MIP-1a and MIP-1b in Human Fetal Microglia. J. Immunol. 160 (1998) 1449-1455
32. Miller D.H., Khan O.A., Sheremata W.A., Blumhardt L.D., Rice G.P.A., Libonati M.A., Willmer-Hulme A.J., Dalton C.M., Miszkiel K.A., and O'Connor P.W. A controlled trial of natalizumab for relapsing multiple sclerosis. The N. Engl. J. Med. 348 (2003) 15-23
33. Moore G.R., McCarron R.M., McFarlin D.E., and Raine C.S. Chronic relapsing necrotizing encephalomyelitis produced by myelin basic protein in mice. Lab. Invest. 57 (1987) 157-167
34. Muller D.M., Pender M.P., and Greer J.M. A neuropathological analysis of experimental autoimmune encephalomyelitis with predominant brain stem and cerebellar involvement and differences between active and passive induction. Acta Neuropathol. 100 (2000) 174-182
35. Prat A., Biernacki K., Lavoie J.F., Poirier J., Duquette P., and Antel J.P. Migration of multiple sclerosis lymphocytes through brain endothelium. Arch. Neurol. 59 (2002) 391-397
36. Raine C.S. Biology of disease. Analysis of autoimmune demyelination: its impact upon multiple sclerosis. Lab. Invest. 50 (1984) 608-635
37. Ransohoff R.M., Hamilton T.A., Tani M., Stoler H.E., Shick J.A., Major M.L., Estes D.M., Thomas D.M., and Tuohy V.K. Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis. FASEB J. 7 (1993) 592-600
38. Shukaliak J.A., and Dorovini-Zis K. Expression of the beta-chemokines RANTES and MIP-1beta by human brain microvessel endothelial cells in primary culture. J. Neuropathol. Exp. Neurol. 59 (2000) 339-352
39. Soilu-Hanninen H., Roytta M., Salmi A., and Salonen R. Therapy with antibody against leukocyte integrin VLA-4 (CD49d) is effective and safe in virus-facilitated experimental allergic encephalomyelitis. J. Neuroimmunol. 72 (1997) 95-105
40. Tani M., Fuentes M.E., Peterson J.W., Trapp B.D., Durham S.K., Loy J.K., Bravo R., Ransohoff R.M., and Lira S.A. Neutrophil infiltration, glial reaction and neurological disease in transgenic mice expressing the chemokine N51/KC in oligodendrocytes. J. Clin. Invest. 98 (1996) 529-539
41. Tran E.H., Hoekstra K., Van Rooijen N., Dijkstra C.D., and Owens T. Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice. J. Immunol. 161 (1998) 3767-3775
42. Vandenbark A.A., Vainiene M., Celnik B., Hashim G., and Offner H. TCR peptide therapy decreases the frequency of encephalitogenic T cells in the periphery and the central nervous system. J. Neuroimmunol. 39 (1992) 251-260
43. Wensky A.K., Furtado G.C., Garibaldi Marcondes M.C., Chen S., Manfra D., Lira S.A., Zagzag D., and Lafaille J.J. IFN-{gamma} Determines Distinct Clinical Outcomes in Autoimmune Encephalomyelitis. J. Immunol. 174 (2005) 1416-1423
44. Yednock T.A., Cannon C., Fritz L.C., Sanchez-Madrid F., Steinman L., and Karin N. Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin. Nature 356 (1992) 63-66
45. Zamvil S.S., Nelson P.A., Mitchell D.J., Knobler R.L., Fritz R.B., and Steinman L. Encephalitogenic T cell clones specific for myelin basic protein. An unusual bias in antigen recognition. J. Exp. Med. 162 (1985) 2107-2124