Role of the simultaneous enhancement of NMDA and dopamine D1 receptor-mediated neurotransmission in the effects of clozapine on phencyclidine-induced acute increases in glutamate levels in the rat medial prefrontal cortex

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 374, Issue 3, 2006, Pages 177-193

  Abekawa, T ^a   Ito, K ^a   Koyama, T ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Clozapine; Dopamine D1; NMDA; Phencyclidine; Treatment resistant schizophrenia

Indexed keywords

2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 4 (3 PHOSPHONOPROPYL) 2 PIPERAZINECARBOXYLIC ACID; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; CLOZAPINE; DOPAMINE 1 RECEPTOR; DOPAMINE 1 RECEPTOR STIMULATING AGENT; GLUTAMIC ACID; HALOPERIDOL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHENCYCLIDINE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; DOPAMINERGIC TRANSMISSION; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; IN VIVO STUDY; LOCOMOTION; MALE; MICRODIALYSIS; NEUROTRANSMISSION; NONHUMAN; PREFRONTAL CORTEX; PSYCHOPHARMACOLOGY; RAT; RATING SCALE; SCORING SYSTEM;

ANALYSIS OF VARIANCE; ANIMALS; ANTIPSYCHOTIC AGENTS; BEHAVIOR, ANIMAL; CLOZAPINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; GLUTAMIC ACID; HALOPERIDOL; HUMANS; MALE; MICRODIALYSIS; MOTOR ACTIVITY; PHENCYCLIDINE; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D1; RECEPTORS, N-METHYL-D-ASPARTATE; SCHIZOPHRENIA;

EID: 33751434111     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-006-0115-9     Document Type: Article

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