Clozapine potentiation of N-Methyl-D-aspartate receptor currents in the nucleus accumbens: Role of NR2B and protein kinase A/Src kinases

Journal of Pharmacology and Experimental Therapeutics

Volumn 313, Issue 2, 2005, Pages 594-603

  Wittmann, Marion ^a   Marino, Michael J ^a   Henze, Darrell A ^a   Seabrook, Guy R ^a   Jeffrey Conn, P ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; ALPHA (2,3 DIMETHOXYPHENYL) 1 [2 (4 FLUOROPHENYL)ETHYL] 4 PIPERIDINEMETHANOL; BISINDOLYLMALEIMIDE; CATECHOLAMINE; CLOZAPINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; DOPAMINE; DOPAMINE 1 RECEPTOR; GLUTAMIC ACID; HALOPERIDOL; IFENPRODIL; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; NEUROLEPTIC AGENT; PROTEIN KINASE C INHIBITOR; SEROTONIN 2A ANTAGONIST; SULPIRIDE;

ANIMAL TISSUE; ARTICLE; BRAIN REGION; BRAIN SLICE; CONTROLLED STUDY; DOPAMINE RELEASE; DRUG MECHANISM; EXCITATORY POSTSYNAPTIC POTENTIAL; NEUROPATHOLOGY; NEUROTRANSMISSION; NONHUMAN; NUCLEUS ACCUMBENS; PATCH CLAMP; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; RAT; SCHIZOPHRENIA; SIGNAL TRANSDUCTION;

ANIMALS; CLOZAPINE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; EXCITATORY POSTSYNAPTIC POTENTIALS; NUCLEUS ACCUMBENS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SRC-FAMILY KINASES;

EID: 18044383936     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.080200     Document Type: Article

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