-
1
-
-
0022504693
-
Non-Enzymatic cleavage and ligation of RNAs complementary to a plant virus satellite RNA
-
Buzayan JM, Gerlach WL, Bruening G: Non-Enzymatic cleavage and ligation of RNAs complementary to a plant virus satellite RNA. Nature 1986, 323:349-353.
-
(1986)
Nature
, vol.323
, pp. 349-353
-
-
Buzayan, J.M.1
Gerlach, W.L.2
Bruening, G.3
-
2
-
-
0023047510
-
Self-cleavage of plus and minus RNA transcripts of avocado sunblotch viroid
-
Hutchins CJ, Rathjen PD, Forster AC, Symons RH: Self-cleavage of plus and minus RNA transcripts of avocado sunblotch viroid. Nucleic Acids Res 1986, 14:3627-3640.
-
(1986)
Nucleic Acids Res
, vol.14
, pp. 3627-3640
-
-
Hutchins, C.J.1
Rathjen, P.D.2
Forster, A.C.3
Symons, R.H.4
-
3
-
-
0026651086
-
Small catalytic RNAs
-
Symons RH: Small catalytic RNAs. Ann Rev Biochem 1992, 61:641-671.
-
(1992)
Ann Rev Biochem
, vol.61
, pp. 641-671
-
-
Symons, R.H.1
-
4
-
-
0023221419
-
A small catalytic oligoribonucleotide
-
Uhlenbeck OC: A small catalytic oligoribonucleotide. Nature 1987, 328:596-600.
-
(1987)
Nature
, vol.328
, pp. 596-600
-
-
Uhlenbeck, O.C.1
-
5
-
-
0024291288
-
Simple RNA enzymes with new and highly specific endoribonuclease activitie
-
Haseloff J, Gerlach WL: Simple RNA enzymes with new and highly specific endoribonuclease activitie. Nature 1988, 334:585-591.
-
(1988)
Nature
, vol.334
, pp. 585-591
-
-
Haseloff, J.1
Gerlach, W.L.2
-
6
-
-
0026529593
-
Extended target-site specificity for a hammerhead ribozyme
-
Perriman R, Delves A, Gerlach WL: Extended target-site specificity for a hammerhead ribozyme. Gene 1992, 113:157-163.
-
(1992)
Gene
, vol.113
, pp. 157-163
-
-
Perriman, R.1
Delves, A.2
Gerlach, W.L.3
-
7
-
-
0028905538
-
Generality of the NUX rule: Kinetic analysis of the results of systematic mutations in the trinucleotide at the cleavage site of hammerhead ribozymes
-
Shimayama T, Nishikawa S, Taira K: Generality of the NUX rule: kinetic analysis of the results of systematic mutations in the trinucleotide at the cleavage site of hammerhead ribozymes. Biochemistry 1995, 34:3649-3654.
-
(1995)
Biochemistry
, vol.34
, pp. 3649-3654
-
-
Shimayama, T.1
Nishikawa, S.2
Taira, K.3
-
8
-
-
0028932288
-
Comparative analysis of cleavage rates after systematic permutation of the NUX consensus target motif for hammerhead ribozymes
-
Zoumadakis M, Tabler M: Comparative analysis of cleavage rates after systematic permutation of the NUX consensus target motif for hammerhead ribozymes. Nucleic Acids Res 1995, 23:1192-1196.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 1192-1196
-
-
Zoumadakis, M.1
Tabler, M.2
-
9
-
-
0026711027
-
Minimum ribonucleotide requirement for catalysis by the RNA hammerhead domain
-
Yang JH, Usman N, Chartrand P, Cedergren R: Minimum ribonucleotide requirement for catalysis by the RNA hammerhead domain. Biochemistry 1992, 31:5005-5009.
-
(1992)
Biochemistry
, vol.31
, pp. 5005-5009
-
-
Yang, J.H.1
Usman, N.2
Chartrand, P.3
Cedergren, R.4
-
10
-
-
0026771509
-
Numbering system for the hammerhead
-
Hertel KJ, Pardi A, Uhlenbeck OC, Koizumi M, Ohtsuka E, Uesugi S, Cedergren R, Eckstein F, Gerlach WL, Hodgson R, Symons RH: Numbering system for the hammerhead. Nucleic Acids Res 1992, 20:3252.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 3252
-
-
Hertel, K.J.1
Pardi, A.2
Uhlenbeck, O.C.3
Koizumi, M.4
Ohtsuka, E.5
Uesugi, S.6
Cedergren, R.7
Eckstein, F.8
Gerlach, W.L.9
Hodgson, R.10
Symons, R.H.11
-
11
-
-
0027227872
-
Nuclease-resistant chimeric ribozymes containing deoxyribonucleotides and phosphorothioate linkages
-
Shimayama T, Nishikawa F, Nishikawa S, Taira K: Nuclease-resistant chimeric ribozymes containing deoxyribonucleotides and phosphorothioate linkages. Nucleic Acids Res 1993, 21:2605-2611.
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 2605-2611
-
-
Shimayama, T.1
Nishikawa, F.2
Nishikawa, S.3
Taira, K.4
-
12
-
-
0026529507
-
Nuclease resistant ribozymes with high catalytic activity
-
Paolella G, Sproat BS, Lamond AI: Nuclease resistant ribozymes with high catalytic activity. EMBO J 1992, 11:1913-1919.
-
(1992)
EMBO J
, vol.11
, pp. 1913-1919
-
-
Paolella, G.1
Sproat, B.S.2
Lamond, A.I.3
-
13
-
-
0026337408
-
Kinetic characterisation of ribonuclease-resistant 2′-modified hammerhead ribozymes
-
Pieken WA, Olsen DB, Benseler F, Aurup H, Eckstein F: Kinetic characterisation of ribonuclease-resistant 2′-modified hammerhead ribozymes. Science 1991, 253:314-317.
-
(1991)
Science
, vol.253
, pp. 314-317
-
-
Pieken, W.A.1
Olsen, D.B.2
Benseler, F.3
Aurup, H.4
Eckstein, F.5
-
14
-
-
0027955448
-
High activity and stability of hammerhead ribozymes containing 2′-modified pyrimidine nucleosides and phosphorothioates
-
Heidenreich O, Benseler F, Fahrenholz A, Eckstein F: High activity and stability of hammerhead ribozymes containing 2′-modified pyrimidine nucleosides and phosphorothioates. J Biol Chem 1994, 269:2131-2138.
-
(1994)
J Biol Chem
, vol.269
, pp. 2131-2138
-
-
Heidenreich, O.1
Benseler, F.2
Fahrenholz, A.3
Eckstein, F.4
-
15
-
-
0030763140
-
Synthesis and properties of hammerhead ribozymes stabilised against nucleases by different 2'-modifications: Methoxyethoxy-, fluoro- and amino groups
-
Scherr M, Klebba C, Haner R, Ganser A, Engels JW: Synthesis and properties of hammerhead ribozymes stabilised against nucleases by different 2'-modifications: methoxyethoxy-, fluoro- and amino groups. Bioorg Med Chem Lett 1997, 7:1791-1796.
-
(1997)
Bioorg Med Chem Lett
, vol.7
, pp. 1791-1796
-
-
Scherr, M.1
Klebba, C.2
Haner, R.3
Ganser, A.4
Engels, J.W.5
-
16
-
-
0028858581
-
Chemical modification of hammerhead ribozymes
-
Beigelman L, McSwiggen JA, Draper KG, Gonzalez C, Jensen K, Karpeisky AM, Modak AS, Matulic-Adamic J, DiRenzo AB, Haeberli P, Sweeder D, Tracz D, Grimm S, Wincott FE, Thackray VG, Usman N: Chemical modification of hammerhead ribozymes. J Biol Chem 1995, 270:25702-25708.
-
(1995)
J Biol Chem
, vol.270
, pp. 25702-25708
-
-
Beigelman, L.1
McSwiggen, J.A.2
Draper, K.G.3
Gonzalez, C.4
Jensen, K.5
Karpeisky, A.M.6
Modak, A.S.7
Matulic-Adamic, J.8
DiRenzo, A.B.9
Haeberli, P.10
Sweeder, D.11
Tracz, D.12
Grimm, S.13
Wincott, F.E.14
Thackray, V.G.15
Usman, N.16
-
19
-
-
0034023696
-
Small, efficient hammerhead ribozymes
-
McCall MJ, Hendry P, Mir AA, Conaty J, Brown G, Lockett TJ: Small, efficient hammerhead ribozymes. Mol Biotechnol 2000, 14:5-17.
-
(2000)
Mol Biotechnol
, vol.14
, pp. 5-17
-
-
McCall, M.J.1
Hendry, P.2
Mir, A.A.3
Conaty, J.4
Brown, G.5
Lockett, T.J.6
-
20
-
-
0029945037
-
Unexpected anisotropy in substrate cleavage rates by asymmetric hammerhead ribozymes
-
Hendry P, McCall MJ: Unexpected anisotropy in substrate cleavage rates by asymmetric hammerhead ribozymes. Nucleic Acids Res 1996, 24:2679-2684.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 2679-2684
-
-
Hendry, P.1
McCall, M.J.2
-
22
-
-
0028587356
-
Characterisation of the carbamoyl phosphate synthetase gene from Plasmodium falciparum
-
Flores MV, O'Sullivan WJ, Stewart TS: Characterisation of the carbamoyl phosphate synthetase gene from Plasmodium falciparum. Mol Biochem Parasitol 1994, 68:315-318.
-
(1994)
Mol Biochem Parasitol
, vol.68
, pp. 315-318
-
-
Flores, M.V.1
O'Sullivan, W.J.2
Stewart, T.S.3
-
23
-
-
0030756990
-
Inhibition of Plasmodium falciparum proliferation in vitro by ribozymes
-
Flores MVC, Atkins D, Wade D, O'Sullivan WJ, Stewart TS: Inhibition of Plasmodium falciparum proliferation in vitro by ribozymes. J Biol Chem 1997, 272:16940-16945.
-
(1997)
J Biol Chem
, vol.272
, pp. 16940-16945
-
-
Flores, M.V.C.1
Atkins, D.2
Wade, D.3
O'Sullivan, W.J.4
Stewart, T.S.5
-
24
-
-
0025771210
-
Ribozyme-catalyzed and nonenzymatic reactions of phosphate diesters: Rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom
-
Herschlag D, Piccirilli JA, Cech TR: Ribozyme-catalyzed and nonenzymatic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom. Biochemistry 1991, 30:4844-54.
-
(1991)
Biochemistry
, vol.30
, pp. 4844-4854
-
-
Herschlag, D.1
Piccirilli, J.A.2
Cech, T.R.3
-
25
-
-
0030877619
-
Hammerhead ribozymes with a faster cleavage rate
-
Clouet-d'Orval B, Uhlenbeck OC: Hammerhead ribozymes with a faster cleavage rate. Biochemistry 1997, 36:9087-9092.
-
(1997)
Biochemistry
, vol.36
, pp. 9087-9092
-
-
Clouet-D'Orval, B.1
Uhlenbeck, O.C.2
-
26
-
-
0033574151
-
RNA folding and misfolding of the hammerhead ribozyme
-
Bassi GS, Mollegaard NE, Murchie AI, Lilley DM: RNA folding and misfolding of the hammerhead ribozyme. Biochemistry 1999, 38:3345-54.
-
(1999)
Biochemistry
, vol.38
, pp. 3345-3354
-
-
Bassi, G.S.1
Mollegaard, N.E.2
Murchie, A.I.3
Lilley, D.M.4
-
27
-
-
0036752786
-
Steric interference modification of the hammerhead ribozyme
-
Blount KF, Grover NL, Mockler V, Beigelman L, Uhlenbeck OC: Steric interference modification of the hammerhead ribozyme. Chem Biol 2002, 9:1009-1016.
-
(2002)
Chem Biol
, vol.9
, pp. 1009-1016
-
-
Blount, K.F.1
Grover, N.L.2
Mockler, V.3
Beigelman, L.4
Uhlenbeck, O.C.5
-
28
-
-
0036903567
-
Folding and activity of the hammerhead ribozyme
-
Hammann C, Lilley DMJ: Folding and activity of the hammerhead ribozyme. ChemBioChem 2002, 3:690-700.
-
(2002)
ChemBioChem
, vol.3
, pp. 690-700
-
-
Hammann, C.1
Lilley, D.M.J.2
-
29
-
-
0038043313
-
Zinc-dependent cleavage in the catalytic core of the hammerhead ribozyme: Evidence for a pH-dependent conformational change
-
Borda EJ, Markley JC, Sigurdsson STh: Zinc-dependent cleavage in the catalytic core of the hammerhead ribozyme: evidence for a pH-dependent conformational change. Nucl Acids Res 2003, 31:2595-2600.
-
(2003)
Nucl Acids Res
, vol.31
, pp. 2595-2600
-
-
Borda, E.J.1
Markley, J.C.2
Sigurdsson, S.Th.3
-
30
-
-
0036293201
-
A pH-dependent conformational change, rather than the chemical step, appears to be rate-limiting in the hammerhead ribozyme cleavage reaction
-
Murray JB, Dunham CM, Scott WG: A pH-dependent conformational change, rather than the chemical step, appears to be rate-limiting in the hammerhead ribozyme cleavage reaction. J Mol Biol 2002, 315:121-130.
-
(2002)
J Mol Biol
, vol.315
, pp. 121-130
-
-
Murray, J.B.1
Dunham, C.M.2
Scott, W.G.3
-
31
-
-
0042509891
-
A helical twist-induced conformational switch activates cleavage in the hammerhead ribozyme
-
Dunham CM, Murray JB, Scott WG: A helical twist-induced conformational switch activates cleavage in the hammerhead ribozyme. J Mol Biol 2003, 332:327-336.
-
(2003)
J Mol Biol
, vol.332
, pp. 327-336
-
-
Dunham, C.M.1
Murray, J.B.2
Scott, W.G.3
-
32
-
-
0029073091
-
The crystal structure of an all-RNA hammerhead ribozyme: A proposed mechanism for RNA catalytic cleavage
-
Scott WG, Finch JT, Klug A: The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage. Cell 1995, 81:991-1002.
-
(1995)
Cell
, vol.81
, pp. 991-1002
-
-
Scott, W.G.1
Finch, J.T.2
Klug, A.3
-
33
-
-
0028063567
-
Three-dimensional structure of a hammerhead ribozyme
-
Pley HW, Flaherty KM, McKay DB: Three-dimensional structure of a hammerhead ribozyme. Nature 1994, 372:68-74.
-
(1994)
Nature
, vol.372
, pp. 68-74
-
-
Pley, H.W.1
Flaherty, K.M.2
McKay, D.B.3
-
34
-
-
1842870632
-
The size of hammerhead ribozyme is related to cleavage kinetics: The role of substrate length
-
Hormes R, Sczakiel G: The size of hammerhead ribozyme is related to cleavage kinetics: the role of substrate length. Biochimie 2002, 84:897-903.
-
(2002)
Biochimie
, vol.84
, pp. 897-903
-
-
Hormes, R.1
Sczakiel, G.2
-
35
-
-
0031020032
-
Complete identification of nonbridging phosphate oxygens involved in hammerhead cleavage
-
Knoll R, Bald R, Furste JP: Complete identification of nonbridging phosphate oxygens involved in hammerhead cleavage. RNA 1997, 3:132-40.
-
(1997)
RNA
, vol.3
, pp. 132-140
-
-
Knoll, R.1
Bald, R.2
Furste, J.P.3
-
36
-
-
0025130635
-
Thiophosphate interference experiments locate phosphates important for the hammerhead RNA self-cleavage reaction
-
Ruffner DE, Uhlenbeck OC: Thiophosphate interference experiments locate phosphates important for the hammerhead RNA self-cleavage reaction. Nucl Acids Res 1990, 18:6025-6029.
-
(1990)
Nucl Acids Res
, vol.18
, pp. 6025-6029
-
-
Ruffner, D.E.1
Uhlenbeck, O.C.2
-
37
-
-
0032998232
-
Enzymatic assignment of diastereomeric purity of stereodefined phosphorothioate oligonucleotides
-
Koziolkiewicz M, Owczarek A, Gendaszewska E: Enzymatic assignment of diastereomeric purity of stereodefined phosphorothioate oligonucleotides. Antisense Nucleic Acid Drug Dev 1999, 9:171-81.
-
(1999)
Antisense Nucleic Acid Drug Dev
, vol.9
, pp. 171-181
-
-
Koziolkiewicz, M.1
Owczarek, A.2
Gendaszewska, E.3
-
38
-
-
0029420163
-
Enzymatic degradation of various antisense oligonucleotides: Monitoring and fragment identification by MECC and ES-MS
-
Maier M, Bleicher K, Kalthoff H, Bayer E: Enzymatic degradation of various antisense oligonucleotides: monitoring and fragment identification by MECC and ES-MS. Biomed Pept Proteins Nucleic Acids 1995, 1:235-42.
-
(1995)
Biomed Pept Proteins Nucleic Acids
, vol.1
, pp. 235-242
-
-
Maier, M.1
Bleicher, K.2
Kalthoff, H.3
Bayer, E.4
-
39
-
-
3142778082
-
RNA interference: Historical overview and significance
-
Montgomery MK: RNA interference: historical overview and significance. Methods Mol Biol 2004, 265:3-21.
-
(2004)
Methods Mol Biol
, vol.265
, pp. 3-21
-
-
Montgomery, M.K.1
-
40
-
-
0043009734
-
Sequence elements outside the hammerhead ribozyme catalytic core enable intracellular activity
-
Khvorova A, Lescoute A, Westhof E, Jayasena SD: Sequence elements outside the hammerhead ribozyme catalytic core enable intracellular activity. Nature Struct Biol 2003, 10:708-712.
-
(2003)
Nature Struct Biol
, vol.10
, pp. 708-712
-
-
Khvorova, A.1
Lescoute, A.2
Westhof, E.3
Jayasena, S.D.4
-
41
-
-
0142105383
-
Peripheral regions of natural hammerhead ribozymes greatly increase their self-cleavage activity
-
De la Pena M, Gago S, Flores R: Peripheral regions of natural hammerhead ribozymes greatly increase their self-cleavage activity. EMBO J 2003, 20:5561-5570.
-
(2003)
EMBO J
, vol.20
, pp. 5561-5570
-
-
De La Pena, M.1
Gago, S.2
Flores, R.3
-
42
-
-
0027166876
-
Accumulation of PDGF B and cell-binding forms of PDGF A in the extracellular matrix
-
Kelly JL, Sanchez A, Brown GS, Chesterman CN, Sleigh MJ: Accumulation of PDGF B and cell-binding forms of PDGF A in the extracellular matrix. J Cell Biol 1993, 121:1153-63.
-
(1993)
J Cell Biol
, vol.121
, pp. 1153-1163
-
-
Kelly, J.L.1
Sanchez, A.2
Brown, G.S.3
Chesterman, C.N.4
Sleigh, M.J.5
-
43
-
-
33751396317
-
-
Kevin Raner Software [http://www.krs.com.au/products.html]
-
-
-
|