Neuronal intranuclear inclusions, dysregulation of cytokine expression and cell death in spinocerebellar ataxia type 3

Clinical Neuropathology

Volumn 25, Issue 6, 2006, Pages 272-281

  Evert, B O ^a   Schelhaas, J ^b   Fleischer, H ^a   De Vos, R A I ^c   Brunt, E R ^b   Stenzel, W ^d   Klockgether, T ^a   Wullner U ^a,e  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c Laboratorium Pathologie Oost Nederland   (Netherlands)

^d UNIVERSITY OF COLOGNE   (Germany)

^e UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

Cell death; Dentate nucleus; Gene expression; IL 1 ; IL 1ra; IL 6; Inflammatory mediators; Neuronal intranuclear inclusions; Pons; SCA3; Transcription factors IRF 1 and C EBP

Indexed keywords

ATAXIN 3; CYTOKINE; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 6;

ADULT; ARTICLE; BRAIN DYSFUNCTION; BRAIN REGION; CELL DEATH; CELL INCLUSION; CENTRAL NERVOUS SYSTEM; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOCHEMISTRY; MALE; MICROGLIA; NERVE CELL; NEUROPROTECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SPINOCEREBELLAR DEGENERATION; UPREGULATION;

AGED; BIOLOGICAL MARKERS; BRAIN; CCAAT-ENHANCER-BINDING PROTEIN-DELTA; CELL DEATH; CELL NUCLEUS; CYTOKINES; FEMALE; GENE EXPRESSION REGULATION; HUMANS; IMMUNOHISTOCHEMISTRY; INTERFERON REGULATORY FACTOR-1; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTRANUCLEAR INCLUSION BODIES; MACHADO-JOSEPH DISEASE; MALE; MICROSCOPY, IMMUNOELECTRON; MIDDLE AGED; NERVE DEGENERATION; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR PROTEINS; REPRESSOR PROTEINS;

EID: 33751338975     PISSN: 07225091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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