-
1
-
-
0022644527
-
Apolipoprotein e polymorphism in the Finnish population: Gene frequencies and relation to lipoprotein concentrations
-
Ehnholm C., Lukka M., Kuusi T., Nikkila E., Utermann G. Apolipoprotein E polymorphism in the Finnish population: gene frequencies and relation to lipoprotein concentrations. J. Lipid Res. 27:1986;227-235.
-
(1986)
J. Lipid Res.
, vol.27
, pp. 227-235
-
-
Ehnholm, C.1
Lukka, M.2
Kuusi, T.3
Nikkila, E.4
Utermann, G.5
-
4
-
-
0027327267
-
Association of apolipoprotein e allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease
-
Saunders A.M., Strittmatter W.J., Schmechel D., George-Hyslop P.H., Pericak-Vance M.A., Joo S.H., Rosi B.L., Gusella J.F., Crapper-MacLachlan D.R., Alberts M.J. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology. 43:1993;1467-1472.
-
(1993)
Neurology
, vol.43
, pp. 1467-1472
-
-
Saunders, A.M.1
Strittmatter, W.J.2
Schmechel, D.3
George-Hyslop, P.H.4
Pericak-Vance, M.A.5
Joo, S.H.6
Rosi, B.L.7
Gusella, J.F.8
Crapper-Maclachlan, D.R.9
Alberts, M.J.10
-
5
-
-
0027194791
-
Gene dose of apolipoprotein e type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder E.H., Saunders A.M., Strittmatter W.J., Schmechel D.E., Gaskell P.C., Small G.W., Roses A.D., Haines J.L., Pericak-Vance M.A. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science. 261:1993;921-923.
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
-
6
-
-
0030823158
-
Effects of age, sex, and ethnicity on the association between apolipoprotein e genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer disease Meta analysis consortium
-
Farrer L.A., Cupples L.A., Haines J.L., Hyman B., Kukull W.A., Mayeux R., Myers R.H., Pericak-Vance M.A., Risch N., van Duijn C.M. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer disease Meta analysis consortium. JAMA. 278:1997;1349-1356.
-
(1997)
JAMA
, vol.278
, pp. 1349-1356
-
-
Farrer, L.A.1
Cupples, L.A.2
Haines, J.L.3
Hyman, B.4
Kukull, W.A.5
Mayeux, R.6
Myers, R.H.7
Pericak-Vance, M.A.8
Risch, N.9
Van Duijn, C.M.10
-
7
-
-
0032839621
-
Apolipoprotein E: From atherosclerosis to Alzheimer's disease and beyond
-
Mahley R.W., Huang Y. Apolipoprotein E: from atherosclerosis to Alzheimer's disease and beyond. Curr. Opin. Lipidol. 10:1999;207-217.
-
(1999)
Curr. Opin. Lipidol.
, vol.10
, pp. 207-217
-
-
Mahley, R.W.1
Huang, Y.2
-
8
-
-
0024299370
-
Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
-
Mahley R.W. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science. 240:1988;622-630.
-
(1988)
Science
, vol.240
, pp. 622-630
-
-
Mahley, R.W.1
-
9
-
-
0024529337
-
Changes of genetic apolipoprotein phenotypes caused by liver transplantation. Implications for apolipoprotein synthesis
-
Kraft H.G., Menzel H.J., Hoppichler F., Vogel W., Utermann G. Changes of genetic apolipoprotein phenotypes caused by liver transplantation. Implications for apolipoprotein synthesis. J. Clin. Invest. 83:1989;137-142.
-
(1989)
J. Clin. Invest.
, vol.83
, pp. 137-142
-
-
Kraft, H.G.1
Menzel, H.J.2
Hoppichler, F.3
Vogel, W.4
Utermann, G.5
-
10
-
-
0025878638
-
Phenotypes of apolipoprotein B and apolipoprotein e after liver transplantation
-
Linton M.F., Gish R., Hubl S.T., Butler E., Esquivel C., Bry W.I., Boyles J.K., Wardell M.R., Young S.G. Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation. J. Clin. Invest. 88:1991;270-281.
-
(1991)
J. Clin. Invest.
, vol.88
, pp. 270-281
-
-
Linton, M.F.1
Gish, R.2
Hubl, S.T.3
Butler, E.4
Esquivel, C.5
Bry, W.I.6
Boyles, J.K.7
Wardell, M.R.8
Young, S.G.9
-
11
-
-
0028825717
-
Evolutionary duplication of a hepatic control region in the human apolipoprotein e gene locus. Identification of a second region that confers high level and liver-specific expression of the human apolipoprotein e gene in transgenic mice
-
Allan C.M., Walker D., Taylor J.M. Evolutionary duplication of a hepatic control region in the human apolipoprotein E gene locus. Identification of a second region that confers high level and liver-specific expression of the human apolipoprotein E gene in transgenic mice. J. Biol. Chem. 270:1995;26278-26281.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 26278-26281
-
-
Allan, C.M.1
Walker, D.2
Taylor, J.M.3
-
12
-
-
0035115847
-
Two distal downstream enhancers direct expression of the human apolipoprotein e gene to astrocytes in the brain
-
Grehan S., Tse E., Taylor J.M. Two distal downstream enhancers direct expression of the human apolipoprotein E gene to astrocytes in the brain. J. Neurosci. 21:2001;812-822.
-
(2001)
J. Neurosci.
, vol.21
, pp. 812-822
-
-
Grehan, S.1
Tse, E.2
Taylor, J.M.3
-
13
-
-
0023899914
-
Expression of the human apolipoprotein e gene is regulated by multiple positive and negative elements
-
Smith J.D., Melian A., Leff T., Breslow J.L. Expression of the human apolipoprotein E gene is regulated by multiple positive and negative elements. J. Biol. Chem. 263:1988;8300-8308.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 8300-8308
-
-
Smith, J.D.1
Melian, A.2
Leff, T.3
Breslow, J.L.4
-
14
-
-
0023741265
-
Identification and characterization of transcriptional regulatory regions associated with expression of the human apolipoprotein e gene
-
Paik Y.K., Chang D.J., Reardon C.A., Walker M.D., Taxman E., Taylor J.M. Identification and characterization of transcriptional regulatory regions associated with expression of the human apolipoprotein E gene. J. Biol. Chem. 263:1988;13340-13349.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 13340-13349
-
-
Paik, Y.K.1
Chang, D.J.2
Reardon, C.A.3
Walker, M.D.4
Taxman, E.5
Taylor, J.M.6
-
15
-
-
0025363021
-
Characterization of a human apolipoprotein e gene enhancer element and its associated protein factors
-
Chang D.J., Paik Y.K., Leren T.P., Walker D.W., Howlett G.J., Taylor J.M. Characterization of a human apolipoprotein E gene enhancer element and its associated protein factors. J. Biol. Chem. 265:1990;9496-9504.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 9496-9504
-
-
Chang, D.J.1
Paik, Y.K.2
Leren, T.P.3
Walker, D.W.4
Howlett, G.J.5
Taylor, J.M.6
-
16
-
-
0027471464
-
A far-downstream hepatocyte-specific control region directs expression of the linked human apolipoprotein e and C-I genes in transgenic mice
-
Simonet W.S., Bucay N., Lauer S.J., Taylor J.M. A far-downstream hepatocyte-specific control region directs expression of the linked human apolipoprotein E and C-I genes in transgenic mice. J. Biol. Chem. 268:1993;8221-8229.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 8221-8229
-
-
Simonet, W.S.1
Bucay, N.2
Lauer, S.J.3
Taylor, J.M.4
-
17
-
-
0027369115
-
Localization of a liver-specific enhancer in the apolipoprotein E/C-I/C-II gene locus
-
Shachter N.S., Zhu Y., Walsh A., Breslow J.L., Smith J.D. Localization of a liver-specific enhancer in the apolipoprotein E/C-I/C-II gene locus. J. Lipid Res. 34:1993;1699-1707.
-
(1993)
J. Lipid Res.
, vol.34
, pp. 1699-1707
-
-
Shachter, N.S.1
Zhu, Y.2
Walsh, A.3
Breslow, J.L.4
Smith, J.D.5
-
18
-
-
0030663731
-
Two hepatic enhancers, HCR.1 and HCR.2, coordinate the liver expression of the entire human apolipoprotein E/C-I/C-IV/C-II gene cluster
-
Allan C.M., Taylor S., Taylor J.M. Two hepatic enhancers, HCR.1 and HCR.2, coordinate the liver expression of the entire human apolipoprotein E/C-I/C-IV/C-II gene cluster. J. Biol. Chem. 272:1997;29113-29119.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 29113-29119
-
-
Allan, C.M.1
Taylor, S.2
Taylor, J.M.3
-
19
-
-
0034644663
-
Duplicated downstream enhancers control expression of the human apolipoprotein e gene in macrophages and adipose tissue
-
Shih S.J., Allan C., Grehan S., Tse E., Moran C., Taylor J.M. Duplicated downstream enhancers control expression of the human apolipoprotein E gene in macrophages and adipose tissue. J. Biol. Chem. 275:2000;31567-31572.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31567-31572
-
-
Shih, S.J.1
Allan, C.2
Grehan, S.3
Tse, E.4
Moran, C.5
Taylor, J.M.6
-
20
-
-
0034518158
-
VISTA: Visualizing global DNA sequence alignments of arbitrary length
-
Mayor C., Brudno M., Schwartz J.R., Poliakov A., Rubin E.M., Frazer K.A., Pachter L.S., Dubchak I. VISTA: visualizing global DNA sequence alignments of arbitrary length. Bioinformatics. 16:2000;1046-1047.
-
(2000)
Bioinformatics
, vol.16
, pp. 1046-1047
-
-
Mayor, C.1
Brudno, M.2
Schwartz, J.R.3
Poliakov, A.4
Rubin, E.M.5
Frazer, K.A.6
Pachter, L.S.7
Dubchak, I.8
-
21
-
-
0032424913
-
Human apolipoprotein e allele-specific brain expressing transgenic mice
-
Smith J.D., Sikes J., Levin J.A. Human apolipoprotein E allele-specific brain expressing transgenic mice. Neurobiol. Aging. 19:1998;407-413.
-
(1998)
Neurobiol. Aging
, vol.19
, pp. 407-413
-
-
Smith, J.D.1
Sikes, J.2
Levin, J.A.3
-
22
-
-
0035261381
-
Genomic strategies to identify mammalian regulatory sequences
-
Pennacchio L.A., Rubin E.M. Genomic strategies to identify mammalian regulatory sequences. Nat. Rev., Genet. 2:2001;100-109.
-
(2001)
Nat. Rev., Genet.
, vol.2
, pp. 100-109
-
-
Pennacchio, L.A.1
Rubin, E.M.2
-
23
-
-
0035888598
-
Hyper-expression of human apolipoprotein E4 in astroglia and neurons does not enhance amyloid deposition in transgenic mice
-
Lesuisse C., Xu G., Anderson J., Wong M., Jankowsky J., Holtz G., Gonzalez V., Wong P.C., Price D.L., Tang F., Wagner S., Borchelt D.R. Hyper-expression of human apolipoprotein E4 in astroglia and neurons does not enhance amyloid deposition in transgenic mice. Hum. Mol. Genet. 10:2001;2525-2537.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 2525-2537
-
-
Lesuisse, C.1
Xu, G.2
Anderson, J.3
Wong, M.4
Jankowsky, J.5
Holtz, G.6
Gonzalez, V.7
Wong, P.C.8
Price, D.L.9
Tang, F.10
Wagner, S.11
Borchelt, D.R.12
-
24
-
-
0022350033
-
Apolipoprotein e associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system
-
Boyles J.K., Pitas R.E., Wilson E., Mahley R.W., Taylor J.M. Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system. J. Clin. Invest. 76:1985;1501-1513.
-
(1985)
J. Clin. Invest.
, vol.76
, pp. 1501-1513
-
-
Boyles, J.K.1
Pitas, R.E.2
Wilson, E.3
Mahley, R.W.4
Taylor, J.M.5
-
25
-
-
0032705473
-
Apolipoprotein e is found in astrocytes but not in microglia in the normal mouse brain
-
Fujita S.C., Sakuta K., Tsuchiya R., Hamanaka H. Apolipoprotein E is found in astrocytes but not in microglia in the normal mouse brain. Neurosci. Res. 35:1999;123-133.
-
(1999)
Neurosci. Res.
, vol.35
, pp. 123-133
-
-
Fujita, S.C.1
Sakuta, K.2
Tsuchiya, R.3
Hamanaka, H.4
-
26
-
-
0023815708
-
Immunohistochemical localization of apolipoprotein e in human glial neoplasms
-
Murakami M., Ushio Y., Morino Y., Ohta T., Matsukado Y. Immunohistochemical localization of apolipoprotein E in human glial neoplasms. J. Clin. Invest. 82:1988;177-188.
-
(1988)
J. Clin. Invest.
, vol.82
, pp. 177-188
-
-
Murakami, M.1
Ushio, Y.2
Morino, Y.3
Ohta, T.4
Matsukado, Y.5
-
27
-
-
0027994092
-
Apolipoprotein e is localized to the cytoplasm of human cortical neurons: A light and electron microscopic study
-
Han S.H., Einstein G., Weisgraber K.H., Strittmatter W.J., Saunders A.M., Pericak-Vance M., Roses A.D., Schmechel D.E. Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study. J. Neuropathol. Exp. Neurol. 53:1994;535-544.
-
(1994)
J. Neuropathol. Exp. Neurol.
, vol.53
, pp. 535-544
-
-
Han, S.H.1
Einstein, G.2
Weisgraber, K.H.3
Strittmatter, W.J.4
Saunders, A.M.5
Pericak-Vance, M.6
Roses, A.D.7
Schmechel, D.E.8
-
28
-
-
0028018114
-
Apolipoprotein e is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls
-
Han S.H., Hulette C., Saunders A.M., Einstein G., Pericak-Vance M., Strittmatter W.J., Roses A.D., Schmechel D.E. Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls. Exp. Neurol. 128:1994;13-26.
-
(1994)
Exp. Neurol.
, vol.128
, pp. 13-26
-
-
Han, S.H.1
Hulette, C.2
Saunders, A.M.3
Einstein, G.4
Pericak-Vance, M.5
Strittmatter, W.J.6
Roses, A.D.7
Schmechel, D.E.8
-
29
-
-
0032562645
-
Regionally specific neuronal expression of human APOE gene in transgenic mice
-
Xu P.T., Gilbert J.R., Qiu H.L., Rothrock-Christian T., Settles D.L., Roses A.D., Schmechel D.E. Regionally specific neuronal expression of human APOE gene in transgenic mice. Neurosci. Lett. 246:1998;65-68.
-
(1998)
Neurosci. Lett.
, vol.246
, pp. 65-68
-
-
Xu, P.T.1
Gilbert, J.R.2
Qiu, H.L.3
Rothrock-Christian, T.4
Settles, D.L.5
Roses, A.D.6
Schmechel, D.E.7
-
30
-
-
0031978926
-
Cis-acting human ApoE tissue expression element is associated with human pattern of intraneuronal ApoE in transgenic mice
-
Roses A.D., Gilbert J., Xu P.T., Sullivan P., Popko B., Burkhart D.S., Christian-Rothrock T., Saunders A.M., Maeda N., Schmechel D.E. Cis-acting human ApoE tissue expression element is associated with human pattern of intraneuronal ApoE in transgenic mice. Neurobiol. Aging. 19:1998;S53-S58.
-
(1998)
Neurobiol. Aging
, vol.19
, pp. 53-S58
-
-
Roses, A.D.1
Gilbert, J.2
Xu, P.T.3
Sullivan, P.4
Popko, B.5
Burkhart, D.S.6
Christian-Rothrock, T.7
Saunders, A.M.8
Maeda, N.9
Schmechel, D.E.10
-
31
-
-
0033574672
-
Synthesis of apolipoprotein e (ApoE) mRNA by human neuronal-type SK N SH-SY 5Y cells and its regulation by nerve growth factor and ApoE
-
Soulie C., Mitchell V., Dupont-Wallois L., Chartier-Harlin M.C., Beauvillain J.C., Delacourte A., Caillet-Boudin M.L. Synthesis of apolipoprotein E (ApoE) mRNA by human neuronal-type SK N SH-SY 5Y cells and its regulation by nerve growth factor and ApoE. Neurosci. Lett. 265:1999;147-150.
-
(1999)
Neurosci. Lett.
, vol.265
, pp. 147-150
-
-
Soulie, C.1
Mitchell, V.2
Dupont-Wallois, L.3
Chartier-Harlin, M.C.4
Beauvillain, J.C.5
Delacourte, A.6
Caillet-Boudin, M.L.7
-
32
-
-
0344267650
-
Specific regional transcription of apolipoprotein e in human brain neurons
-
Xu P.T., Gilbert J.R., Qiu H.L., Ervin J., Rothrock-Christian T.R., Hulette C., Schmechel D.E. Specific regional transcription of apolipoprotein E in human brain neurons. Am. J. Pathol. 154:1999;601-611.
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 601-611
-
-
Xu, P.T.1
Gilbert, J.R.2
Qiu, H.L.3
Ervin, J.4
Rothrock-Christian, T.R.5
Hulette, C.6
Schmechel, D.E.7
-
33
-
-
0025826774
-
Astrocytic apolipoprotein e mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning
-
Poirier J., Hess M., May P.C., Finch C.E. Astrocytic apolipoprotein E mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning. Brain Res. Mol. Brain Res. 11:1991;97-106.
-
(1991)
Brain Res. Mol. Brain Res.
, vol.11
, pp. 97-106
-
-
Poirier, J.1
Hess, M.2
May, P.C.3
Finch, C.E.4
-
34
-
-
0029782194
-
Selective alterations in the cellular distribution of apolipoprotein e immunoreactivity following transient cerebral ischaemia in the rat
-
Horsburgh K., Nicoll J.A. Selective alterations in the cellular distribution of apolipoprotein E immunoreactivity following transient cerebral ischaemia in the rat. Neuropathol. Appl. Neurobiol. 22:1996;342-349.
-
(1996)
Neuropathol. Appl. Neurobiol.
, vol.22
, pp. 342-349
-
-
Horsburgh, K.1
Nicoll, J.A.2
-
35
-
-
0033427722
-
Apolipoprotein e expression by neurons surviving excitotoxic stress
-
Boschert U., Merlo-Pich E., Higgins G., Roses A.D., Catsicas S. Apolipoprotein E expression by neurons surviving excitotoxic stress. Neurobiol. Dis. 6:1999;508-514.
-
(1999)
Neurobiol. Dis.
, vol.6
, pp. 508-514
-
-
Boschert, U.1
Merlo-Pich, E.2
Higgins, G.3
Roses, A.D.4
Catsicas, S.5
-
36
-
-
0030175279
-
Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: Human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice
-
Xu P.T., Schmechel D., Rothrock-Christian T., Burkhart D.S., Qiu H.L., Popko B., Sullivan P., Maeda N., Saunders A.M., Roses A.D., Gilbert J.R. Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice. Neurobiol. Dis. 3:1996;229-245.
-
(1996)
Neurobiol. Dis.
, vol.3
, pp. 229-245
-
-
Xu, P.T.1
Schmechel, D.2
Rothrock-Christian, T.3
Burkhart, D.S.4
Qiu, H.L.5
Popko, B.6
Sullivan, P.7
Maeda, N.8
Saunders, A.M.9
Roses, A.D.10
Gilbert, J.R.11
-
37
-
-
0035660423
-
Apolipoprotein C-I expression in the brain in Alzheimer's disease
-
Petit-Turcotte C., Stohl S.M., Beffert U., Cohn J.S., Aumont N., Tremblay M., Dea D., Yang L., Poirier J., Shachter N.S. Apolipoprotein C-I expression in the brain in Alzheimer's disease. Neurobiol. Dis. 8:2001;953-963.
-
(2001)
Neurobiol. Dis.
, vol.8
, pp. 953-963
-
-
Petit-Turcotte, C.1
Stohl, S.M.2
Beffert, U.3
Cohn, J.S.4
Aumont, N.5
Tremblay, M.6
Dea, D.7
Yang, L.8
Poirier, J.9
Shachter, N.S.10
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