Characterization of the 5' flanking region and potential control elements of the ovine follitropin receptor gene

Molecular Reproduction and Development

Volumn 48, Issue 4, 1997, Pages 480-487

  Sairam, M R ^a,b   Subbarayan, V S R ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

Alternative splicing; FSH receptor gene cloning; Regulatory elements; Structural motifs; Transcription start site

Indexed keywords

FOLLITROPIN RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; DNA FLANKING REGION; DNA SEQUENCE; FOLLITROPIN BLOOD LEVEL; FOLLITROPIN RELEASE; GENE CONTROL; GENE EXPRESSION; HORMONE BLOOD LEVEL; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ALTERNATIVE SPLICING; ANIMALS; BASE SEQUENCE; BINDING SITES; CLONING, MOLECULAR; DNA, COMPLEMENTARY; EXONS; GENE EXPRESSION REGULATION; HUMANS; INTRONS; MALE; MICE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; RATS; RECEPTORS, FSH; SEQUENCE HOMOLOGY, NUCLEIC ACID; SHEEP; SPECIES SPECIFICITY; TESTIS;

EID: 0030775902     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2795(199712)48:4<480::AID-MRD8>3.0.CO;2-M     Document Type: Article

References (57)

1. Cedar H (1988): DNA methylation and gene activity. Cell 53:3-4.
2. Delmas V, Sassone-Corsi P (1994): The key role of CREM in the cAMP signaling pathway in the testis. Mol Cell Endocrinol 100:121-124.
3. Devereux J (1992): The GCG Sequence Analysis Software Package, Version 7.1, Genetics Computer Group, University Research Park, Madison, WI.
4. Feinberg AP, Vogelstein B (1983): A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132:6-13.
5. Foo NC, Funkhouser JM, Carter DA, Murphy D (1994): A testis specific promoter in the rat vasopressin gene. J Biol Chem 269:659-667.
6. Gromoll J, Dankbar B, Gudermann T (1994): Characterization of the 5′-flanking region of the human follicle stimulating hormone receptor gene. Mol Cell Endocrinol 88:55-66.
7. Gromoll J, Gudermann T, Nieschlag E (1992): Molecular cloning of a truncated isoform of the human follicle stimulating hormone receptor. Biochem Biophys Res Comm 188:1077-1083.
8. Hall SH, Joseph DR, French FS, Conti M (1988): Follicle stimulating hormone induces transient expression of protooncogene c-fos in primary Sertoli cell cultures. Mol Endocrinol 2:55-61.
9. Hamil KG, Conti M, Shimasaki S, Hall SH (1994): Follicle stimulating hormone regulation of AP-1: Inhibition of c-Jun and stimulation of Jun B gene transcription in rat Sertoli cell. Mol Cell Endocrinol 99:269-277.
10. Heckert LL, Daley IJ, Griswold MD (1992): Structural organization of the follicle-stimulating hormone receptor gene. Mol Endocrinol 6:70-80.
11. Howard TE, Shai SY, Langford KG, Martin BM, Bernstein KE (1990): Transcription of testicular angiotensin-converting enzyme (ACE) is initiated within the 12th intron of the somatic ACE gene. Mol Cell Biol 10:4294-4302.
12. Huhtaniemi IT, Eskola V, Pakarinen P, Matikainen T, Sprengel R (1992): The murine luteinizing hormone and follicle stimulating hormone receptor genes: Transcription initiation sites, putative promoter sequences and promoter activity. Mol Cell Endocrinol 88:55-66.
13. Jiang L, Sairam MR, Rassoulzadegan M, Cuzan F (1996): Expression of FSH receptor in tumor Sertoli cell line derived from adult transgenic mice: A model to study hormone action. Biol Reproduction 54:abs 192.
14. Kelton CA, Cheng SVY, Nugent NP, Schweickhardt RL, Rosenthal JL, Overton SA, Wands GD, Kuzeja JB, Luchette CA, Chappel SC (1992): The cloning of the human follicle stimulating hormone receptor and its expression in COS-7, CHO, and Y-1 cells. Mol Cell Endocrinol 89:141-151.
15. Keren TI, Dantes A, Sprengel R, Amsterdam A (1993): Establishment of steroidogenic granulosa cell lines expressing follicle stimulating hormone receptors. Mol Cell Endocrinol 95:1-10.
16. Khan H, Jiang L, Jayashree GN, Yarney TA, Sairam MR (1997): Recognition of follicle stimulating hormone (alpha subunit) by a recombinant receptor protein domain coded by an alternately spliced messenger RNA and expressed in E. Coll. J Mol Endocrinol 20:000-000.
17. Khan H, Yarney TA, Sairam MR (1993): Cloning of alternately spliced mRNA transcripts coding for variants of ovine testicular follitropin receptor lacking the G protein coupling domains. Biochem Biophys Res Comm 190:888-894.
18. Kilgour RJ, Courot M, Pisselet C, Dubois MP, Sairam MR (1993): Inhibition of FSH affects spermatogenesis in the mature ram. Anim Reprod Sci 32:213-225.
19. Koo YB, Ji I, Slaughter RG, Ji TH (1991): Structure of the LH receptor gene and multiple exons of the coding sequences. Endocrinology 128:2297-2308.
20. Lee SL, Sadovsky Y, Swirnoff AH, Polish JA, Goda P, Gavrlina G, Milbrandt J (1996): Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1). Science 273:1219-1221.
21. Lerchl A, Sotiviadon S, Behre HM, Pierce J, Weinbauer GF, Nieschlag E (1993): Restoration of spermatogenesis by follicle stimulating hormone despite low intratesticular testosterone in photoinhibited hypogonadotropic djungarian hamster (P. surgorus). Biol Reprod 49:1108-1117.
22. Loosefelt H, Misrahi M, Atger M, Salesse R, Thi MT, Jolivet A, Guichon-Mantel A, Sar S, Jallal B, Gamier J, Milgrom E (1989): Cloning and sequencing of porcine LH-hCG receptor cDNA: Variants lacking transmembrane domain. Science 245:525-528.
23. Matsumoto AM, Karpas AE, Bremner WJ (1986): Chronic human chorionic gonadotropin administration in normal men: Evidence that follicle stimulating hormone is necessary for maintenance of quantitative normal spermatogenesis in men. J Clin Endocrinol Metab 62:1184-1190.
24. McFarland KC, Sprengel R, Philips HS, Kohler M, Rosemblit N, Nikolics K, Segaloff DL, Seeburg PH (1989) Lutropin-choriogonadotropin receptor: An unusual member of the G protein coupled receptor family. Science 245:494-499.
25. Means AR, Dedman JR, Tindall JS, Van Sickle M, Welsh MJ (1980): Regulation of testis Sertoli cells by follicle stimulating hormone. Ann Rev Physiol 42:59-70.
26. Miller CD, Miller WL (1996): Transcriptional repression of the ovine follicle stimulating hormone beta gene by 17-beta estradiol. Endocrinology 137:3437-3446.
27. Mishrahi M, Loosefelt H, Gross B, Atger M, Jolivet A, Savouret JF, Milgrom E (1994): Characterization of the thyroid stimulating hormone receptor. Curr Opinion Endocrinol Metab 1:175-183.
28. Moudgal NR, Ravindranath N, Murthy GS, Dighe RR, Aravinda GR, Martin F (1992): Long term contraceptive efficacy of vaccine of ovine follicle stimulating hormone in male bonnet monkeys (Macaca radiata). J Reprod Fert 96:91-102.
29. O'Shaughnessy PJ, Dudley K (1993): Discrete splicing alternatives in mRNA encoding the extracellular domain of the testis FSH receptor in normal and hypogonadal mouse. J Mol Endocrinol 10:363-366.
30. Orth J, Christensen AK (1978): Autoradiographic localization of specifically bound 125 I labeled follicle stimulating hormone on spermatogonia of the rat testis. Endocrinology 103:1944-1951.
31. 125I labeled FSH in the testis of hypophysectomized rats by autoradiography at the light and electron microscopic levels. Endocrinology 103:1944-1951.
32. Pierce JG, Parsons TF (1981): Glycoprotein hormones: Structure and function. Ann Rev Biochem 50:465-496.
33. Rajendrakumar T, Wang Y, Lu N, Matzuk (1997): Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility. Nature Genet 15:201-204.
34. Rannikki AS, Zhang FP, Huhtaniemi IT (1995): Ontogeny of follicle-stimulating hormone receptor gene expression in the rat testis and ovary. Mol Cell Endocrinol 107:199-208.
35. Rannikko A, Pentilla JL, Zhang FP, Toppari J, Parvinen M, Huhtaniemi I (1996): Stage specific expression of FSH receptor gene in the prepubertal and adult rat seminiferous epithelium. J Endocrinol 151:29-35.
36. Richards JS (1994): Hormonal control of gene expression in the ovary. Endocrin Rev 15:725-751.
37. Sairam MR, Subbarayan VSR (1996): Characterization of the structure of ovine follicle stimulating hormone (FSH) receptor gene. Biol Reproduction 54:Abs 63.
38. Sairam MR (1981): Primary structure of the ovine pituitary follitropin alpha subunit. Biochem J 197:535-539.
39. Sairam MR (1983): Gonadotropic hormones: Relationship between structure and function with emphasis on antagonists. In CH Li. (ed): Hormonal Proteins and Peptides, Vol. 11, Gonadotropins. New York: Academic Press, pp 1-79.
40. Sairam MR, Jiang LG, Khan H, Yarney TA (1996a): A cytokine/growth factor receptor type for pituitary follitropin: Implication for the pleiotropic actions of the hormone. 10th Int Cong Endocrinol, San Francisco, Abs P3-297.
41. Sairam MR, Jiang LG, Yarney TA, Khan H (1997): Alternative splicing converts the G-protein coupled pituitary follitropin receptor gene into a growth factor type I receptor: Implications for pleiotropic actions of hormones. Mol Reprod Dev 48:471-479.
42. Sairam MR, Jiang LG, Yarney TA, Khan H (1996b): Follitropin signal transduction: Alternative splicing of the FSH receptor gene produces a dominant negative form of receptor which inhibits hormone action. Biochem Biophys Res Commun 226:717-722.
43. Sairam MR, Seidah NG, Chretien M (1981): Primary structure of the ovine pituitary follitropin beta subunit. Biochem J 197:541-552.
44. nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
45. Sanger F, Nicklen S, Coulson AR (1977): DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74:5463-5467.
46. Sharp PA (1994): Split genes and RNA splicing. Cell 77:805-815.
47. Skinner MK (1991): Cell-cell interactions in the testis. Endocrin Rev 12:45-77.
48. Sprengel R, Braun T, Nikolics K, Segaloff DL, Seeburg PH (1990): The testicular receptor for follicle stimulating hormone: structure and functional expression of cloned cDNA. Mol Endocrinol 4:525-530.
49. Themmen APN, Krajj R, Grootegoed JA (1994): Regulation of gonadotropin receptor gene expression. Mol Cell Endocrinol 100:15-19.
50. Tisdall DJ, Watanabe K, Hudson, Smith P, Mc Natty KP (1995) FSH receptor gene expression during ovarian follicle development in sheep. J Mol Endocrinol 15:273-281.
51. Truss M, Beato M (1993): Steroid hormone receptors: Interaction with deoxyribonucleic acid and transcription factors. Endocrin Rev 14: 459-479.
52. Tsai-Morris CH, Buczko EE, Wang W, Xie XZ, Dufau ML (1991): Structural organization of the rat luteinizing hormone (LH) receptor gene. J Biol Chem 266:11355-11359.
53. Yarney TA, Fahmy MH, Sairam MR, Khan H, Macdonald EA (1997b): Ontogeny of FSH receptor messenger ribonucleic acid transcripts in relation to FSH secretion and testicular function in sheep. J Mol Endocrinol 18:113-125.
54. Yarney TA, Jiang L, Khan H, Macdonald EA, Laird DW, Sairam MR (1997a): Molecular cloning, structure and expression of a testicular follitropin receptor with selective alteration in the carboxy terminus that affects signaling function. Mol Reprod Dev 48:458-470.
55. Yarney TA, Sairam MR, Khan H, Ravindranath N, Payne S, Seidah NG (1993): Molecular cloning and expression of the ovine testicular follicle stimulating hormone receptor. Mol Cell Endocrinol 93:219-226.
56. Yee JB, Hutson JC (1985): In vivo effects of follicle stimulating hormone on testicular macrophages. Biol Reprod 32:880-883.
57. Yiu GK, Murray MT, Hecht NB (1997): Deoxyribonucleic acid-protein interactions associated with transcriptional initiation of the mouse testis-specific cytochrome c gene. Biol Reprod 56:1439-1449.