-
2
-
-
15144347577
-
Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs
-
Chan C., Yin H., Garforth J., McKie J.H., Jaouhari R., Speers P., Douglas K.T., Rock P.J., Yardley V., Croft S.L., and Fairlamb A.H. Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs. Journal of Medicinal Chemistry 41 (1998) 148-156
-
(1998)
Journal of Medicinal Chemistry
, vol.41
, pp. 148-156
-
-
Chan, C.1
Yin, H.2
Garforth, J.3
McKie, J.H.4
Jaouhari, R.5
Speers, P.6
Douglas, K.T.7
Rock, P.J.8
Yardley, V.9
Croft, S.L.10
Fairlamb, A.H.11
-
3
-
-
0021327406
-
Entamoeba histolytica: a eukaryote without glutathione metabolism
-
Fahey R.C., Newton G.L., Arrick B., Overdank-Bogart T., and Aley S.B. Entamoeba histolytica: a eukaryote without glutathione metabolism. Science 224 (1984) 70-72
-
(1984)
Science
, vol.224
, pp. 70-72
-
-
Fahey, R.C.1
Newton, G.L.2
Arrick, B.3
Overdank-Bogart, T.4
Aley, S.B.5
-
4
-
-
0022002912
-
Trypanothione: a novel bis (glutathionyl) spermidine cofactor for glutathione reductase in trypanosomatids
-
Fairlamb A.H., Blackburn P., Ulrich P., Chait B.T., and Cerami A. Trypanothione: a novel bis (glutathionyl) spermidine cofactor for glutathione reductase in trypanosomatids. Science 227 (1985) 1485-1487
-
(1985)
Science
, vol.227
, pp. 1485-1487
-
-
Fairlamb, A.H.1
Blackburn, P.2
Ulrich, P.3
Chait, B.T.4
Cerami, A.5
-
5
-
-
0025630099
-
Acanthamoeba keratitis-resistance to medical therapy
-
Ficker L., Seal D., Warhurst D., and Wright P. Acanthamoeba keratitis-resistance to medical therapy. Eye 4 Pt. 6 (1990) 835-838
-
(1990)
Eye
, vol.4
, Issue.PART 6
, pp. 835-838
-
-
Ficker, L.1
Seal, D.2
Warhurst, D.3
Wright, P.4
-
6
-
-
0033504307
-
Results of a trial of combined propamidine isethionate and neomycin therapy for Acanthamoeba keratitis
-
Hargrave S.L., McCulley J.P., and Husseini Z. Results of a trial of combined propamidine isethionate and neomycin therapy for Acanthamoeba keratitis. Brolene Study Group. Ophthalmology 106 (1999) 952-957
-
(1999)
Brolene Study Group. Ophthalmology
, vol.106
, pp. 952-957
-
-
Hargrave, S.L.1
McCulley, J.P.2
Husseini, Z.3
-
7
-
-
0030057025
-
Crystal structure of the Trypanosoma cruzi trypanothione reductase mepacrine complex
-
Jacoby E.M., Schlichting I., Lantwin C.B., Kabsch W., and Krauth-Siegel R.L. Crystal structure of the Trypanosoma cruzi trypanothione reductase mepacrine complex. Proteins 24 1 (1996) 73-80
-
(1996)
Proteins
, vol.24
, Issue.1
, pp. 73-80
-
-
Jacoby, E.M.1
Schlichting, I.2
Lantwin, C.B.3
Kabsch, W.4
Krauth-Siegel, R.L.5
-
8
-
-
0000915313
-
Opportunistically pathogenic free-living amebae
-
Kreier J.P., and Baker J.R. (Eds), Academic Press Inc., San Diego, California
-
John D.T. Opportunistically pathogenic free-living amebae. In: Kreier J.P., and Baker J.R. (Eds). Parasitic Protozoa. second ed. vol. 3 (1993), Academic Press Inc., San Diego, California 143-246
-
(1993)
Parasitic Protozoa. second ed.
, vol.3
, pp. 143-246
-
-
John, D.T.1
-
9
-
-
0032955828
-
Evidence for the co-existence of glutathione reductase and trypanothione reductase in the nontrypanosomatid Euglenozoa: Euglena gracilis Z
-
Montrichard F., Le Guen F., Laval-Martin L.D., and Davioud-Charvet E. Evidence for the co-existence of glutathione reductase and trypanothione reductase in the nontrypanosomatid Euglenozoa: Euglena gracilis Z. FEBS Letters 442 (1999) 29-33
-
(1999)
FEBS Letters
, vol.442
, pp. 29-33
-
-
Montrichard, F.1
Le Guen, F.2
Laval-Martin, L.D.3
Davioud-Charvet, E.4
-
10
-
-
0033751002
-
In vivo inhibition of reduced thiol compounds from Entamoeba histolytica HK9 by phenothiazines and related tricyclic drugs
-
Ondarza R.N., Iturbe A., Hernandez E., Tamayo E.M., and Hurtado G. In vivo inhibition of reduced thiol compounds from Entamoeba histolytica HK9 by phenothiazines and related tricyclic drugs. Archives of Medical Research 31 Suppl. 4 (2000) S12-S16
-
(2000)
Archives of Medical Research
, vol.31
, Issue.SUPPL. 4
-
-
Ondarza, R.N.1
Iturbe, A.2
Hernandez, E.3
Tamayo, E.M.4
Hurtado, G.5
-
11
-
-
0033858325
-
Inhibitory and lytic effects of phenothiazine derivatives and related tricyclic neuroleptic compounds, on Entamoeba histolytica HK9 and HM1 trophozoites
-
Ondarza R.N., Hernandez E., Iturbe A., and Hurtado G. Inhibitory and lytic effects of phenothiazine derivatives and related tricyclic neuroleptic compounds, on Entamoeba histolytica HK9 and HM1 trophozoites. Biotechnology and Applied Biochemistry 32 Pt. 1 (2000) 61-67
-
(2000)
Biotechnology and Applied Biochemistry
, vol.32
, Issue.PART 1
, pp. 61-67
-
-
Ondarza, R.N.1
Hernandez, E.2
Iturbe, A.3
Hurtado, G.4
-
12
-
-
0036918038
-
Thiol compounds from a free-living opportunistic amoeba, Acanthamoeba polyphaga
-
Ondarza R.N., Iturbe A., Hernández E., and Hurtado G. Thiol compounds from a free-living opportunistic amoeba, Acanthamoeba polyphaga. Biotechnology and Applied Biochemistry 36 (2002) 195-204
-
(2002)
Biotechnology and Applied Biochemistry
, vol.36
, pp. 195-204
-
-
Ondarza, R.N.1
Iturbe, A.2
Hernández, E.3
Hurtado, G.4
-
13
-
-
0037383319
-
Low-molecular-mass thiol compounds from a free-living highly pathogenic amoeba, Naegleria fowleri
-
Ondarza R.N., Iturbe A., Hernández E., and Hurtado G. Low-molecular-mass thiol compounds from a free-living highly pathogenic amoeba, Naegleria fowleri. Biotechnology and Applied Biochemistry 37 (2003) 195-204
-
(2003)
Biotechnology and Applied Biochemistry
, vol.37
, pp. 195-204
-
-
Ondarza, R.N.1
Iturbe, A.2
Hernández, E.3
Hurtado, G.4
-
14
-
-
26844544308
-
Identification of trypanothione from the human pathogen Entamoeba histolytica by mass spectrometry and chemical analysis
-
Ondarza R.N., Hurtado G., Iturbe A., Hernández E., Tamayo E., and Woolery M. Identification of trypanothione from the human pathogen Entamoeba histolytica by mass spectrometry and chemical analysis. Biotechnology and Applied Biochemistry 42 (2005) 175-181
-
(2005)
Biotechnology and Applied Biochemistry
, vol.42
, pp. 175-181
-
-
Ondarza, R.N.1
Hurtado, G.2
Iturbe, A.3
Hernández, E.4
Tamayo, E.5
Woolery, M.6
-
15
-
-
33745653270
-
-
Ondarza, R.N., Iturbe, A., Hernández, E., 2006a. Antiproliferative Effects In vitro by Neuroleptics, Antimycotics and Antibiotics, on the Human Pathogens Acanthamoeba polyphaga and Naegleria fowleri. Archives of Medical Research (in press).
-
-
-
-
16
-
-
33749639792
-
-
Ondarza, R.N., Hurtado,G., Tamayo, E.,Iturbe, A., Hernandez, E., 2006b. Naegleria fowleri: A free-living highly pathogenic amoeba contains trypanothione/trypanothione reductase and glutathione/glutathione reductase systems. Experimental Parasitology (in press).
-
-
-
-
17
-
-
0023096450
-
Amoebae isolated from the atmosphere of Mexico City and environs
-
Rivera F., Roy-Ocotla G., Rosas I., Rami{dotless}́rez E., Bonilla P., and Lares F. Amoebae isolated from the atmosphere of Mexico City and environs. Environmental Research 42 1 (1987) 149-154
-
(1987)
Environmental Research
, vol.42
, Issue.1
, pp. 149-154
-
-
Rivera, F.1
Roy-Ocotla, G.2
Rosas, I.3
Ramírez, E.4
Bonilla, P.5
Lares, F.6
-
18
-
-
3142719178
-
Two interacting binding sites for quinacrine derivatives in the active site of trypanothione reductase: a template for drug design
-
Saravanamuthu A., Vickers T.J., Bond C.S., Peterson M.R., Hunter W.N., and Fairlamb A.H. Two interacting binding sites for quinacrine derivatives in the active site of trypanothione reductase: a template for drug design. Journal of Biological Chemistry 279 28 (2004) 29493-29500
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.28
, pp. 29493-29500
-
-
Saravanamuthu, A.1
Vickers, T.J.2
Bond, C.S.3
Peterson, M.R.4
Hunter, W.N.5
Fairlamb, A.H.6
-
19
-
-
0023051830
-
Purification and characterization of trypanothione reductase from Crithidia fasciculata, a newly discovered member of the family of disulfide-containing flavoprotein reductases
-
Shames S.L., Fairlamb A.H., Cerami A., and Walsh C.T. Purification and characterization of trypanothione reductase from Crithidia fasciculata, a newly discovered member of the family of disulfide-containing flavoprotein reductases. Biochemistry 25 (1986) 3519-3526
-
(1986)
Biochemistry
, vol.25
, pp. 3519-3526
-
-
Shames, S.L.1
Fairlamb, A.H.2
Cerami, A.3
Walsh, C.T.4
-
20
-
-
17144363571
-
Trypanothione reductase from the human parasite Entamoeba histolytica: a new drug target
-
Tamayo E.M., Iturbe A., Hernández E., Hurtado G., Gutiérrez - X.M.L., Rosales J.L., Woolery M., and Ondarza R.N. Trypanothione reductase from the human parasite Entamoeba histolytica: a new drug target. Biotechnology and Applied Biochemistry 41 (2005) 105-115
-
(2005)
Biotechnology and Applied Biochemistry
, vol.41
, pp. 105-115
-
-
Tamayo, E.M.1
Iturbe, A.2
Hernández, E.3
Hurtado, G.4
Gutiérrez -, X.M.L.5
Rosales, J.L.6
Woolery, M.7
Ondarza, R.N.8
|