Study of polysomy of chromosome 7, monosomy of chromosome 10, EGFR gene amplification and p53 deletion in glioblastoma multiforme using fluorescent in situ hybridization (FISH);Studium polyzomie chromozomu 7, monozomie chromozomu 10, amplifikace genu EGFR a delece genu p53 u multiformního glioblastomu pomocí metody fluorescenční in situ hybridizace (FISH)

Klinicka Onkologie

Volumn 19, Issue 1, 2006, Pages 9-14

  Necesalova E ^a   Kuglik P ^a   Cejpek, P ^b   Veselska R ^a   Vranova R ^a   Pesakova M ^b   Relichova J ^a  

^a MASARYK UNIVERSITY   (Czech Republic)

^b UNIVERSITY HOSPITAL BRNO   (Czech Republic)

Author keywords

Chromosomal abnormalities; Fluorescence in situ hybridization; Gene EGFR amplification; Gene p53 deletion; Glioblastoma multiforme; Monosomy of chromosome 10; Polysomy of chromosome 7

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN P53;

ARTICLE; CHROMOSOME 10; CHROMOSOME 7; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE DELETION; GLIOBLASTOMA; HUMAN; HUMAN TISSUE; MOLECULAR GENETICS; MONOSOMY; MORBIDITY; POLYSOMY;

EID: 33751070343     PISSN: 0862495X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Mao, X., Hamouni, R.A. Molecular and cytogenetic analysis of glioblastoma multiforme: Cancer Genetics and Cytogenetics, 2000, s. 87-92.
2. Batchelor, T.T., Bebetsky, R.A., Esposito, J.M., et. al.: Age-dependet prognostic effects of genetic alterations in glioblastoma, 2004, 10, s. 228-233.
3. The Medical Research Council Brain Tumor Working Party: Randomized trial of procarbazine, lomustine and vincristine in the adjuvant treament of high-grade astrocytoma: a Medical Research Council trial, J. Clin. Oncol., 2001, 19, s. 509-518
4. Bruce, J.: Glioblastoma multiforme, eMedicine Journal, 2001, 2, posting date. [Online]. [March 8, 2002, last date accessed].
5. Amalfitano, G., Chatek, M., Paquis, P., Michiels, J.F.: Fluorescence in situ hybridization study of chromosomes 7, 10, X and Y in primary and secondary glioblastomas, Cancer Genet Cytogenet, 2000, 116, s. 6-9.
6. Gayatry, M., Bollen, A.W., Kim, D., et. al.: Genetic Analysis of Glioblastoma Multiforme provides Evidence for Subgroups Within the Grade, Genes Chromosome Cancer, 1998, 21, s. 195-206.
7. Loeper, S., Romeike, BMF., Heckman, N., et. al.: Frequent mitotic errors in tumor cell of genetically micro- heterogeneous glioblastomas, Cytogenet Cell Genet, 2001, 94, s. 1-8.
8. Put-Ti-Noi, S., Petmitr, S., Chanyavanich, V., et. al.: Chromosome 10 and 17 deletions and p53 gene mutations in Thai patiens with astrocytomas, Oncol Rep., 2004, 11(1), s. 207-211.
9. Arslantas, A., Hrtan, S., Oner, U., et. al.: The importace of genomic copy number changes in the prognosis of glioblastoma multiforme, Neurosurg Rev., 2004, 27(1), s. 58-64.
10. Jung, V., Romeike, B.F.M., Wolfram, H., et. al.: Evidence of Focal Microheterogenity in Glioblastoma Multiforme by Area-Specific CGH on Microdissected Tumor Cells, Journal of Neuropathology and Experimental Neurology, 1999, 9, s. 993-999.
11. Wiltshire, R.N., Rasheed, B.K.A., Friedman, A.H.F., Bigner, S.H.: Comparative genetic patterns of glioblastoma multiforme: Potential diagnostic tool for tumor classification, Neuro-Oncology, 2000, 2, s. 164-173.
12. Huhn, S.L., Mohapatra, G., Bollen, A., et. al.: Chromosomal abnormalities in glioblastoma multiforme by comparative genomic hybridization: Correlation with radiation treatment outcome, Clinical Cancer Research. 1999, 5, s. 1435-1443.
13. Mohapatra, G., Bolen, A.W., Kim, D.H., et. al.: Genetic Analysis of Glioblastoma Multiforme Provides Evidence for Subgroups Within the Grade, Genes Chromosome Cancer, 1998, 21, s. 195-206.
14. Dichamp, C., Taillibert, S., Aguirre-Cruz, L., et. al.: Loss of 14q chromosome in oligodendroglial and astrocytic tumors, J Neurooncol., 2004, 67(3), s. 281-285.
15. Zainuddin , N., Jaafart, H., Isa, M.N., Abdullah, J.M.: Loss of heterozygosity on chromosomes 10q, 9p, 17p and 13q in malays with malignant glioma, Neurol Res., 2004, 26(1), s. 88-92.
16. Stark, AM., Witzel, P., Strege, RJ., et. al.: p53, mdm2, EGFR and msh2 expression in paired initial and recurrent glioblastoma multiforme, J Neurol Neurosurg Psychiatry, 2003, 74(6), s. 779-783.
17. Hui, A.B., Lo K.W., Yin, X.L., et. al.: Detection of multiple gene amplification in glioblastoma multiforme using array-based comparative genomic hybridization, Lab Invest, 2001, 81(5), s. 717-723.
18. Biernat, W., Huang, H., Yokoo, H., et. al.: Predominant expression of mutant EGFR (EGFRvIII) is rare in primary glioblastomas. Brain Pathol., 2004, 14(2), s. 131-136.
19. Sauter, G., Maeda, T., Walkman, F.M., et. al.: Patterns of epidermal growth factor receptor amplification in malignit gliomas. Am J Pathol., 1996, 148, s. 1047-1053.
20. Watanabe, K., Tachibana, O., Saita, K., et. al.: Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. Brain Pathol., 1996, 5, s. 217-223.
21. Bigner, S.H., Mark, J., Bullard, D.E., et. al.: Chromosomal evolution in malignant human gliomas starts with specific and usually numerical deviations. Cancer Genet Cytogenet., 1986, 22, s. 121-135.
22. Henn, H., Blin, N., Zang, K.D. Polysomy of chromosome 7 is correlated with overexpression of the erbB oncogene in human glioblastoma cell lines. Hum Genet, 1986, 74:104-106.
23. Thiel, G., Losanova, T., Kintzel, D., et. al. Karyotypes in 90 human gliomas. Cancer Genet Cytogenet., 1992, 58:109-120.
24. Hilton, D.A., Melling, C. Genetic markers in the assessment of intrinsic brain tumours. Current Diagnostic Patholoby, 2004, 10:38-92
25. Fujisawa, H., Reis, R.M., Nakamura, M., Colella, S.: Loss of Heteozygosity on Chromosome 10 Is More Extensive in Primary (De Novo) Than in Secondary Glioblastomas. Laboratory investigation, 2000, 80(1), s. 65-72
26. Kato, H., Kato, S., Kumabe, T., Sonoda, Y.: Functional Evaluation of p53 and PTEN Gene Mutations in Gliomas. Clinical Cancer Research, 2000, 6, s. 3937-3943.
27. Smith, S.J., Tachibana, I., Passe, S.M., Huntley, B.K.: PTEN Mutation, EGFR Amplification, and Outcome in Patients With Anaplastic Astrocytoma and Glioblastoma Multiforme. Journal of the National Cancer Institute, 2001, 93, s. 1246-1256.
28. Wessels, P.H., Twijnstra, A., Kubat, B., et. al.: 10q25.3 (DMBT1) copy number changes in astrocytoma grades II and IV. Genes Chromosomes Cancer, 2004, 39(1), s. 22-28.
29. Balesaria, S., Brock, C., Bower, M., Clark, J.: Loss of chromosome 10 is an independent prognostic factor in high-grade gliomas. British Journal of Cancer, 1999, 81(8), s. 1371-1377.
30. Sprenger, S., Schuuring, J., Wesseling, P., et. al.: Clinical implications of high grade gliomas into 4 grous based on CGH analysis.
31. Nishizaki, T., Harada, K., Kubota, H., et. al.: Chromosome instability in malignant astrocytic tumors detected by fluorescence in situ hybridization. J Neurooncol., 2002, 56(2), s. 159-165.
32. Summons, M.L., Lamborn, K.R., Takahashi, M., et. al.: Analysis of Complex Relationships between Age, p53, Epidermal Growth Factor Receptor, and Survival in Glioblastoma Patiens. Cancer Research., 2001, 61, s. 1122-1128.
33. Barker, F.G., Simmons, M.L., Chang, S.M., et. al.: EGFR oversexpression and radiation response in glioblastoma multiforme. Int J Radiat Oncol Biol Phys, 2001, 51(2), s. 410-418.
34. Liu, K.J., Chen, C.T., Hu, W.S., et. al.: Expression of cytoplasmic-domain substituted epidermal growth factor receptor inhibits tumorigenicity of EGFR-overexpressed human glioblastoma multiforme. Int J Oncol., 2004, 24(3), s. 581-590.
35. Wang, T.J., Huang, M.S., Hong, C.Y., et. al.: Comparisons of tumor suppressor p53, p21, and p16 gene therapy effects on glioblastoma tumorigenicity in situ. Biochem Biophys Res Commun., 2001, 287(1), s. 173-80.
36. Krex, D., Mohr, B., Appelt, H., et. al.: Genetic analysis of a multifocal glioblastoma multiforme: a suitable tool to gain new aspect in glioma development. Neurosurgery, 2003, 53(6), s. 1377-84.
37. Ranuncolo, S.M., Varela, M., Morandi, A., et. al.: Prognostic Value of Mdm2, p53 and p16 in Patients with Astrocytomas. Journal of Neuro-Oncology, 2004, s. 113-121.
38. vanMeyel, D.J., Ramsay, D.A., Casson, A.G., et. al.: p53 mutation, expression, and DNA ploidy in envolving gliomas: evidence for two pathways of progression. J Natl Cancer Inst., 1994, 86(13), s. 1011-1017.
39. Lopez-Gines, C., Cerda-Nicolas, M., Gil-Benso, R., et. al.: Characterization by FISH and molecular studies of different subtypes of glioblastoma multiforme.