Chromosomal abnormalities in glioblastoma multiforme by comparative genomic hybridization: Correlation with radiation treatment outcome

Clinical Cancer Research

Volumn 5, Issue 6, 1999, Pages 1435-1443

  Huhn, Stephen L ^a,b   Mohapatra, Gayatry ^a   Bollen, Andrew ^a   Lamborn, Kathleen ^a   Prados, Michael D ^a   Feuerstein, Burt G ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER RADIOTHERAPY; CANCER RESISTANCE; CHROMOSOME 13Q; CHROMOSOME 9P; CHROMOSOME LOSS; CLINICAL ARTICLE; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; CORRELATION FUNCTION; FEMALE; GLIOBLASTOMA; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; RADIOSENSITIVITY; TREATMENT OUTCOME;

ADULT; AGED; BRAIN NEOPLASMS; CHROMOSOME ABERRATIONS; CHROMOSOME DISORDERS; CHROMOSOME MAPPING; COHORT STUDIES; DISEASE PROGRESSION; FEMALE; GENE AMPLIFICATION; GLIOBLASTOMA; HUMANS; MALE; MIDDLE AGED; NUCLEIC ACID HYBRIDIZATION; SEQUENCE DELETION; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 0033048809     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Sandberg, A. A., and Yurc-Carel, C. The cytogenetics of solid tumors: relation to diagnosis, classification, and pathology. Cancer (Phila.), 59: 387-395, 1987.
2. Seeger, R. C., Brodeur, G. M., Sather, H., Dalton, A., Siegel, S. E., Wong, K. Y., and Hammond, D. Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastoma. N. Engl. J. Med., 313: 1111-1116, 1985.
3. Caron, H., van Sluis, P., de Kraker, J., Bokkerink, J., Egeler, M., Laureys, G., Slater, R., Westerveld, A., Voute, P. A., and Versteeg, R. Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma. N. Engl. J. Med., 334: 225-230, 1996.
4. Morris, M. D., Bordow, S. B., Marshall, G. M., Haber, P. S., Cohn, S. L., and Haber, M. Expression of the gene for multidrug-resistance-associated protein and outcome in patients with neuroblastoma. N. Engl. J. Med., 334: 231-238, 1996.
5. Heselmeyer, K., Schrock, E., du Manoir, S., Blegen, H., Shah, K., Steinbeck, R., Auer, G., and Ried, T. Gain of chromosome 3q defines the transition from severe dysplasia to invasive carcinoma of the uterine cervix. Proc. Natl. Acad. Sci. USA, 93: 479-484, 1996.
6. Moch, H., Presti, J. C., Sauter, G., Buchholz, N., Jordan, P., Mihatsch, M. J., and Waldman, F. M. Genetic aberrations detected by comparative genomic hybridization are associated with clinical outcome in renal cell carcinoma. Cancer Res., 56: 27-30, 1996.
7. Kimmel, D. W., O'Fallon, J. R., Scheithauer, B. W., Kelly, P. J., Dewald, G. W., and Jenkins, R. B. Prognostic value of cytogenetic analysis in human cerebral astrocytomas. Ann. Neurol., 31: 534-542, 1992.
8. Bigner, S. H., Burger, P. C., Wong, A. J., Werner, M. H., Hamilton, S. R., Muhlbaier, L. H., Vogelstein, B., and Bigner, D. D. Gene amplification in malignant human glioma: clinical and histopathologic aspects. J. Neuropathol. Exp. Neurol., 47: 191-205, 1988.
9. Hurtt, M. R., Moossy, J., Donovan-Peluso, M., and Locker, J. Amplification of epidermal growth factor receptor gene in gliomas: histopathology and prognosis. J. Neuropathol. Exp. Neurol., 51: 84-90, 1992.
10. Salmon, I., Dewitte, O., Pasteels, J. L., Flament-Durand, J., Brotchi, J., Vereerstraeten, P., and Kiss, R. Prognostic scoring in adult astrocytic tumors using patient age, histopathological grade, and DNA histogram type. J. Neurosurg., 80: 877-883, 1994.
11. Kleihues, P., Burger, P. C., and Scheithauer, B. W. Histological Typing of Tumors of the Central Nervous System, Ed. 2. Berlin: Springer-Verlag, 1993.
12. Salcman, M. Glioblastoma and malignant astrocytoma. In: A. H. Kaye and E. R. Laws (eds.), Brain Tumors, pp. 449-477. New York: Churchill Livingslon, 1995.
13. Walker, M. D., Green, S. B., Byar, D. P., Alexander, E., Batzdorf, U., Brooks, W. H., Hunt, W. E., MacCarty, C. S., Mahaley, M. S., Mealey, J., Owens, G., Ransohoff, J., Robertson, J. T., Shapiro, W. R, Smith, K. R., Wilson, C. B., and Strike, T. A. Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery. N. Engl. J. Med., 303: 1323-1329, 1980.
14. Walker, M. D., Alexander, E., Hunt, W. E., MacCarty, C. S., Mahaley, M. S., Mealey, J., Norrell, H. A., Owens, G., Ransohoff, J., Wilson, C. B., Gehan, E. A., and Strike, T. A. Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas: a cooperative clinical trial. J. Neurosurg., 49: 333-343, 1978.
15. Brada, M., and Ross, G., Radiation therapy in the management of malignant gliomas. Bailliere's Clin. Neurol., 5: 319-343, 1996.
16. Barker, F. B., Prados, M. D., Chang, S. M., Gutin, P. H., Lamborn, K. R., Larson, D. A., Malec, M. K., McDermott, M. W., Sneed, P. K., Wara, W. M., and Wilson, C. B. Radiation response and survival time in patients with glioblastoma multiforme. J. Neurosurg., 84: 442-448, 1996.
17. Lee, J. M., Abrahamson, J. L., and Bernstein, A. DNA damage, oncogenesis, and the p53 tumor-suppressor gene. Mutat. Res., 307: 573-581, 1994.
18. Kallioniemi, A., Kallioniemi O. P., Sudar, D., Rutovitz, D. Gray, J. W., Waldman, F., and Pinkel, D. Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science (Washington DC), 258: 818-821, 1992.
19. Kallioniemi, O. P., Kallioniemi, A., Sudar, D., Rutovitz, D., Gray, J. W., Waldman, F., and Pinkel, D. Comparative genomic hybridization: a rapid new method for detecting and mapping DNA amplification in tumors. Semin. Cancer Biol., 4: 41-46, 1993.
20. Kallioniemi, A., Kallionieme, O. P., Piper, J., Tanner, M., Stokke, T., Chen, L., Smith, H. S., Pinkel, D. Gray, J. W., and Waldman, F. M. Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization. Proc. Natl. Acad. Sci. USA, 91: 2156-2160, 1994.
21. Kim, D. H., Mohapatra, G., Bollen, A., Waldman, F. M., and Feuerstein, B. G. Chromosomal abnormalities in glioblastoma multiforme tumors and glioma cell lines detected by comparative genomic hybridization. Int. J. Cancer, 60: 812-819, 1995.
22. Mohapatra, G., Kim, D. G., and Feuerstein, B. G. Detection of multiple gains and losses of genetic material in ten glioma cell lines by comparative genomic hybridization. Genes Chromosomes Cancer, 13: 86-93, 1995.
23. Schrock, E., Thiel, G., Lozanowa, T., du Manoir, S., Meffert, M. C., Jauch, A., Speicher, M. R., Nurnberg, P., Vogel, S., Werner, J., Donis-Keller, H., Ried, T., Witkowski, R., and Cremer, T. Comparative genomic hybridization of human malignant gliomas reveals multiple amplification sites and nonrandom chromosomal gains and losses. Am. J. Pathol., 144: 1203-1218, 1994.
24. Mohapatra, G., Moore, D. H., Kim, D. H., Grewal, L., Hyun, W. C., Waldman, F. M., Pinkel, D., and Feuerstein, B. G. Analysis of brain tumor cell lines confirms a simple model of relationships among fluorescence in situ hybridization, DNA index, and comparative genomic hybridization. Genes Chromosomes Cancer, 20: 311-319, 1997.
25. Hoshino, T., Prados, M., Wilson, C. B., Cho, K. G., Lee, K. S., and Davis, R. L. Prognostic implications of the bromodeoxyuridine labeling index of human gliomas. J. Neurosurg., 71: 335-341, 1989.
26. Sambrook, J., Fritsch, E. F., and Maniatis, T. Molecular Cloning: A Laboratory Manual, Ed. 1. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1989.
27. Piper, J., Rutovitz, D., Sudar, D., Kallioniemi, A., Kallioniemi, O. P., Waldman, F. M., Gray, J. W., and Pinkel, D. Computer image analysis of comparative genomic hybridization. Cytometry, 19: 10-26, 1995.
28. Guichard, M, Dertinger, H., and Malaise, E. P. Radiosensitivity of four human tumor xenografts: influence of hypoxia and cell-cell contact. Radiat. Res., 95: 602-609, 1983.
29. Jenkins, R. B., Kimel, D. W., Moertel, C. A., Schultz, C. G., Scheithauer, B. W., Kelly, P. J., and Dewald, G. W. A cytogenetic study of 53 human gliomas. Cancer Genet. Cytogenet., 39: 253-279, 1989.
30. Bigner, S. H., Mark, J., and Bigner, D. D. Cytogenetics of human brain tumors. Cancer Genet. Cytogenet., 47: 141-154, 1990.
31. Cavenee, W. K., Accumulation of genetic defects during astrocytoma progression. Cancer (Phila.), 70 (Suppl.): 1788-1793, 1992.
32. Rey, J. A., Pestana, A., and Bello, M. J. Cytogenetics and molecular genetics of nervous system tumors. Oncol. Res., 4: 321-331, 1992.
33. Leon, S. P., Zhu, J., and Black, P. Genetic aberrations in human brain tumors. Neurosurgery, 34: 708-722, 1994.
34. Weber, R. G., Sommer, C., Albert, F. K., Kiessling, M., and Cremer, T. Clinically distinct subgroups of glioblastoma multiforme studied by comparative genomic hybridization. Lab. Invest., 74: 108-119, 1996.
35. Bigner, S. H., Mark, J., Bullard, D. E., Mahaley, M. S., and Bigner, D. D. Chromosomal evolution in malignant human glioma starts with specific and usually numerical deviations. Cancer Genet. Cytogenet., 22: 121-135, 1986.
36. Schrock, E., Blume, C., Meffert, M. C., du Manoir, S., Bersch, W., Kiessling, M., Lozanowa, T., Thiel, G., Witkowski, R., and Ried, T. Recurrent gain of chromosome arm 7q in low-grade astrocytic tumors studied by comparative genomic hybridization. Genes Chromosomes Cancer, 15: 199-205, 1996.
37. Johansson, B., Heim, S., Mandahl, N., Mertens, F., and Mitelman, F. Trisomy 7 in non-neoplastic cells. Genes Chromosomes Cancer, 6: 199-205, 1993.
38. Heim, S., Mandahl, N., Jin, Y., Stromblad, S. Lindstrom, E., Salford, L. G., and Mitelman, F. Trisomy 7 and sex chromosome loss in human brain tissue. Cytogenet. Cell Genet., 52: 136-138, 1989.
39. Thiel, G., Lozanowa, T., Vogel, S., Kintzel, D., Janisch, W., and Witkowski, R. Age dependent nonrandom chromosomal abnormalities in human low-grade astrocytomas. Hum. Genet., 91: 547-550, 1993.
40. Hensen, J. W., Schnitker, B. L., Correa, K. M., von Deimling, A., Fassbender, F., Xu, H. J., Benedict, W. F., Yandell, D. W., and Louis, D. N. The retinoblastoma gene is involved in malignant progression of astrocytomas. Ann. Neurol., 36: 714-721, 1994.
41. Hamel, W., Westphal, M., and Shepard, H. M. Loss in expression of the retinoblastoma gene product in human gliomas is associated with advanced disease. J. Neuro-Oncol., 16: 159-165, 1993.
42. Furnari, F. B., Su Huang, H-J., and Cavenee, W. K. Molecular biology of malignant degeneration of astrocytoma. Pediatr. Neurosurg., 24: 41-49, 1996.
43. Lukas, J., Parry, D., Aagaard, L., Mann, D. J., Bartkova, J., Strauss, M., Peters, G., and Bartek, J. Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16. Nature (Lond.), 375: 503-506, 1995.
44. Kamb, A., Gruis, N. A., Weaver-Feldhaus, J., Liu, Q., Harshman, K., Tavtigian, S. V., Stockert, E., Day, R. S., Johnson, B. E., and Skolnick, M. H. A cell cycle regulator potentially involved in genesis of many tumor types. Science (Washington DC), 264: 436-440, 1994.
45. Nobori, T., Miura, K., Wu, D. J., Lois, A., Takabayashi, K., and Carson, D. A. Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature (Lond.), 68: 753-756, 1994.
46. Sonoda, Y., Yoshimoto, T., and Sekiya, T. Homozygous deletion of the MTS1/p16 and MTS2/p15 genes and amplification of the CDK4 gene in glioma. Oncogene, 11: 2145-2149, 1995.
47. Ueki, K., Ono, Y., Henson, J. W., Efird, J. T., von Deimling, A., and Louis, D. N. CDKN2/p16 orRB alterations occur in the majority of glioblastomas and are inversely correlated. Cancer Res., 56: 150-153, 1996.