Life-long vitamin C supplementation in combination with cold exposure does not affect oxidative damage or lifespan in mice, but decreases expression of antioxidant protection genes

Mechanisms of Ageing and Development

Volumn 127, Issue 12, 2006, Pages 897-904

  Selman, Colin ^a   McLaren, Jane S ^a   Meyer, Claus ^b   Duncan, Jackie S ^b   Redman, Paula ^a   Collins, Andrew R ^b   Duthie, Garry G ^b   Speakman, John R ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b ROWETT RESEARCH INSTITUTE   (United Kingdom)

Author keywords

Gene expression; Longevity; Metabolic rate; Oxidative stress; Vitamin C

Indexed keywords

ASCORBIC ACID; DNA; GLUTATHIONE PEROXIDASE;

ANIMAL EXPERIMENT; ARTICLE; BODY MASS; COLD EXPOSURE; CONTROLLED STUDY; DNA DAMAGE; DNA MICROARRAY; DOWN REGULATION; ENERGY METABOLISM; FEMALE; GENE EXPRESSION; LIFESPAN; LIPID PEROXIDATION; LIVER CELL; LONG TERM CARE; MOUSE; NONHUMAN; NORTHERN BLOTTING; OXIDATIVE STRESS; PRIORITY JOURNAL; VITAMIN SUPPLEMENTATION;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; COLD; DIETARY SUPPLEMENTS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; LIPID PEROXIDATION; LONGEVITY; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; VITAMINS;

ANIMALIA;

EID: 33750997598     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2006.09.008     Document Type: Article

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