1-Methylpyridinium-4-(4-phenylmethanethiosulfonate) iodide, MTS-MPP+, a novel scanning cysteine accessibility method (SCAM) reagent for monoamine transporter studies

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 1, 2007, Pages 305-311

  Gallardo Godoy, Alejandra ^a   Torres Altoro, Melissa I ^a   White, Kellie J ^a   Barker, Eric L ^a   Nichols, David E ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

MPP+; Mutagenesis; SCAM reagent; Serotonin transporter

Indexed keywords

1 METHYLPYRIDINIUM 4 (4 PHENYLMETHANETHIOSULFONATE)IODIDE; [2 (TRIMETHYLAMMONIUM)ETHYL]METHANETHIOSULFONATE; CYSTEINE; REAGENT; SEROTONIN TRANSPORTER; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

AMINE TRANSPORT; ARTICLE; CHEMICAL LABELING; SENSITIVITY AND SPECIFICITY; SYNTHESIS;

CELL LINE; CYSTEINE; HUMANS; IODIDES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PYRIDINIUM COMPOUNDS; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33750954752     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.09.058     Document Type: Article

References (25)

1. Shaked Z., Szajewski R.P., and Whitesides G.M. Biochemistry 19 (1980) 4156
2. Bruice T.W., and Kenyon G.L. J. Protein Chem. 1 (1982) 47
3. Stauffer D.A., and Karlin A. Biochemistry 33 (1994) 6840
4. Javitch J.A., Li X., Kaback J., and Karlin A. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 10355
5. Javitch J.A., Fu D., Chen J., and Karlin A. Neuron 14 (1995) 825
6. Javitch J.A., Fu D., and Chen J. Mol. Pharmacol. 49 (1996) 692
7. Javitch J.A. Adv. Pharmacol. 42 (1998) 412
8. Javitch J.A. Methods Enzymol. 296 (1998) 331
9. Javitch J.A., Shi L., Simpson M.M., Chen J., Chiappa V., Visiers I., Weinstein H., and Ballesteros J.A. Biochemistry 39 (2000) 12190
10. Javitch J.A., Shi L., and Liapakis G. Methods Enzymol. 343 (2002) 137
11. Shi L., Simpson M.M., Ballesteros J.A., and Javitch J.A. Biochemistry 40 (2001) 12339
12. Kitayama S., Shimada S., and Uhl G.R. Ann. Neurol. 32 (1992) 109
13. Inazu M., Kubota N., Takeda H., Oguchi K., Koizumi M., Kimura S., and Matsumiya T. Neurochem. Int. 39 (2001) 253
14. Martel F., and Keating E. Placenta 24 (2003) 361
15. Dohi T., Kitayama S., Morioka N., Kumagai K., Mitsuhata C., Morita K., Kozai K., Lin Z., and Uhl G.R. Nihon Shinkei Seishin Yakurigaku Zasshi 24 (2004) 43
16. Bentley M.D., Douglass I.B., and Lacadie J.A. J. Org. Chem. 37 (1972) 333
17. Henry L.K., Adkins E.M., Han Q., and Blakely R.D. J. Biol. Chem. 278 (2003) 37052
18. Chen J.G., Liu-Chen S., and Rudnick G. Biochemistry 36 (1997) 1479
19. Mager S., Min C., Henry D.J., Chavkin C., Hoffman B.J., Davidson N., and Lester H.A. Neuron 12 (1994) 845
20. Lin F., Lester H.A., and Mager S. Biophys. J. 71 (1996) 3126
21. Yamashita A., Singh S.K., Kawate T., Jin Y., and Gouaux E. Nature 437 (2005) 215
22. White K.J., Kiser P.D., Nichols D.E., and Barker E.L. Protein Sci. 15 (2006) 2411
23. Brikh A., and Morin C. J. Organomet. Chem. 581 (1999) 82
24. Combellas C., Dellerue S., Mathey G., and Thiebault A. Tetrahedron Lett. 38 (1997) 539
25. Raghavan S., Rajender A., Joseph S., and Rasheed M.A. Synth. Commun. 31 (2001) 1477