Mapping the Binding-Site Crevice of the D2 Receptor

Advances in Pharmacology

Volumn 42, Issue C, 1997, Pages 412-415

  Javitch, Jonathan A ^a  

^a Surgeons Columbia University and New York State Psychiatric institute New York ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77956783230     PISSN: 10543589     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1054-3589(08)60776-0     Document Type: Article

References (5)

1. Akabas M.H., Stauffer D.A., Xu M., and Karlin A. Acetylcholine receptor channel structure probed in cysteine-substitution mutants. Science 258 (1992) 307-310
2. Javitch J.A., Li X., Kaback J., and Karlin A. A cysteine residue in the third membrane-spanning segment of the human dopamine D2 receptor is exposed in the binding-site crevice. Proc. Natl. Acad. Sci. U.S.A 91 (1994) 10355-10359
3. Javitch J.A., Fu D., Chen J., and Karlin A. Mapping the binding-site crevice of the dopamine D2 dopamine receptor by the substituted-cysteine accessibility method. Neuron 14 (1995) 825-831
4. Javitch J.A., Fu D., and Chen J. Residues in the fifth membrane-spanning segment of the dopamine D2 receptor exposed in the binding-site crevice. Biochemistry 34 (1995) 16433-16439
5. Fu D., Ballesteros J.A., Weinstein H., Chen J., and Javitch J.A. Residues in the seventh membrane-spanning segment of the dopamine D2 receptor accessible in the binding-site crevice. Biochemistry 35 (1996) 11278-11285