메뉴 건너뛰기




Volumn 24, Issue 4, 2003, Pages 361-369

Uptake of 1-methyl-4-phenylpyridinium (MPP+) by the JAR human placental choriocarcinoma cell line: Comparison with 5-hydroxytryptamine

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; CARRIER PROTEIN; CORTICOSTERONE; CYANINE 863; DECYNIUM 22; DESIPRAMINE; EXTRANEURONAL MONOAMINE TRANSPORTER; FLUOXETINE; ORGANIC CATION TRANSPORTER 2; PROTEIN INHIBITOR; SEROTONIN; SEROTONIN TRANSPORTER; SODIUM ION; TRITIUM; UNCLASSIFIED DRUG;

EID: 0038131135     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1053/plac.2002.0917     Document Type: Article
Times cited : (19)

References (47)
  • 2
    • 0024548912 scopus 로고
    • Evidence for an imipramine-sensitive serotonin transporter in human placental brush-border membranes
    • Balkowetz DF, Tiruppathi C, Leibach FH, Mahesh VB & Ganapathy V (1989) Evidence for an imipramine-sensitive serotonin transporter in human placental brush-border membranes. J Biol Chem, 264, 2195-2198.
    • (1989) J. Biol. Chem. , vol.264 , pp. 2195-2198
    • Balkowetz, D.F.1    Tiruppathi, C.2    Leibach, F.H.3    Mahesh, V.B.4    Ganapathy, V.5
  • 4
    • 0000416021 scopus 로고
    • Lactate dehydrogenase
    • (Ed.) Bergmeyer HU, New York: Academic Press
    • Bergmeyer HU & Bernt E (1974) Lactate dehydrogenase. In Methods in Enzymatic Analysis (Ed.) Bergmeyer HU, pp. 574-579. New York: Academic Press.
    • (1974) Methods in Enzymatic Analysis , pp. 574-579
    • Bergmeyer, H.U.1    Bernt, E.2
  • 5
    • 0017184389 scopus 로고
    • A rapid method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM (1976) A rapid method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem, 72, 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 6
    • 0026091764 scopus 로고
    • Expression and cyclic AMP-dependent regulation of a high affinity serotonin transporter in the human placental choriocarcinoma cell line (JAR)
    • Cool DR, Leibach FH, Bhalla VK, Mahesh VB & Ganapathy V (1991) Expression and cyclic AMP-dependent regulation of a high affinity serotonin transporter in the human placental choriocarcinoma cell line (JAR). J Biol Chem, 266, 15750-15757.
    • (1991) J. Biol. Chem. , vol.266 , pp. 15750-15757
    • Cool, D.R.1    Leibach, F.H.2    Bhalla, V.K.3    Mahesh, V.B.4    Ganapathy, V.5
  • 7
    • 0025640901 scopus 로고
    • + after administration of lethal and sublethal doses of MPTP to mice
    • + after administration of lethal and sublethal doses of MPTP to mice. Toxicol Lett, 54, 253-262.
    • (1990) Toxicol. Lett. , vol.54 , pp. 253-262
    • Fuller, R.W.1    Hemrick-Luecke, S.K.2
  • 8
    • 0025988085 scopus 로고
    • MPTP mechanisms of neurotoxicity and their implications for Parkinson's disease
    • Gerlach M, Riederer P, Przuntek H & Youdim MBH (1991) MPTP mechanisms of neurotoxicity and their implications for Parkinson's disease. Eur J Pharmacol, 208, 273-286.
    • (1991) Eur. J. Pharmacol. , vol.208 , pp. 273-286
    • Gerlach, M.1    Riederer, P.2    Przuntek, H.3    Youdim, M.B.H.4
  • 10
    • 0042840641 scopus 로고    scopus 로고
    • Primary structure and functional expression of the apical organic cation transporter from kidney epithelial LLC-PK1 cells
    • Gründemann D, Babin-Ebell J, Martel F, Örding N, Schmidt A & Schömig E (1997) Primary structure and functional expression of the apical organic cation transporter from kidney epithelial LLC-PK1 cells. J Biol Chem, 272, 10408-10413.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10408-10413
    • Gründemann, D.1    Babin-Ebell, J.2    Martel, F.3    Örding, N.4    Schmidt, A.5    Schömig, E.6
  • 11
    • 0032150876 scopus 로고    scopus 로고
    • Molecular identification of the corticosterone-sensitive extraneuronal monoamine transporter
    • Gründemann D, Schechinger B, Rappold GA & Schömig E (1998) Molecular identification of the corticosterone-sensitive extraneuronal monoamine transporter. Nat Neurosci, 1, 349-351.
    • (1998) Nat. Neurosci. , vol.1 , pp. 349-351
    • Gründemann, D.1    Schechinger, B.2    Rappold, G.A.3    Schömig, E.4
  • 13
    • 0000340348 scopus 로고
    • Parkinsonism-inducing neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: Uptake of the metabolite N-methyl-4-phenylpyridinium by dopamine neurons explains selective toxicity
    • Javitch JA, D'Amato RJ, Strittmatter SM & Snyder SH (1985) Parkinsonism-inducing neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridinium by dopamine neurons explains selective toxicity. Proc Natl Acad Sci USA, 82, 2173-2177.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 2173-2177
    • Javitch, J.A.1    D'Amato, R.J.2    Strittmatter, S.M.3    Snyder, S.H.4
  • 14
    • 0032569029 scopus 로고    scopus 로고
    • Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta
    • Kekuda R, Prasad PD, Wu X, Wang H, Fei YJ, Leibach FH & Ganapathy V (1998) Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta. J Biol Chem, 273, 15971-15979.
    • (1998) J. Biol. Chem. , vol.273 , pp. 15971-15979
    • Kekuda, R.1    Prasad, P.D.2    Wu, X.3    Wang, H.4    Fei, Y.J.5    Leibach, F.H.6    Ganapathy, V.7
  • 15
    • 0002946770 scopus 로고
    • Mechanisms of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced destruction of dopaminergic neurons
    • (Ed.) Herken H & Hucho F, Berlin: Springer-Verlag
    • Kopin IJ (1992) Mechanisms of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced destruction of dopaminergic neurons. In Selective Neurotoxicity (Handb Exp Pharmacol, Vol. 102) (Ed.) Herken H & Hucho F, pp. 333-356. Berlin: Springer-Verlag.
    • (1992) Selective Neurotoxicity (Handb. Exp. Pharmacol.) , vol.102 , pp. 333-356
    • Kopin, I.J.1
  • 16
    • 0027401022 scopus 로고
    • The pharmacology of Parkinson's disease therapy: An update
    • Kopin IJ (1993) The pharmacology of Parkinson's disease therapy: an update. Ann Rev Pharmacol Toxicol, 32, 467-495.
    • (1993) Ann. Rev. Pharmacol. Toxicol. , vol.32 , pp. 467-495
    • Kopin, I.J.1
  • 20
    • 0032100774 scopus 로고    scopus 로고
    • Effect of bile duct obstruction on hepatic uptake of 1-methyl-4-phenylpyridinium in the rat
    • Martel F, Calhau C & Hipólito-Reis C (1998) Effect of bile duct obstruction on hepatic uptake of 1-methyl-4-phenylpyridinium in the rat. Pharmacol Res, 37, 497-504.
    • (1998) Pharmacol. Res. , vol.37 , pp. 497-504
    • Martel, F.1    Calhau, C.2    Hipólito-Reis, C.3
  • 22
    • 0030299963 scopus 로고    scopus 로고
    • 3H]-1-methyl-4-phenylpyridinium in rat isolated hepatocytes: Putative involvement of a P-glycoprotein transporter
    • 3H]-1-methyl-4-phenylpyridinium in rat isolated hepatocytes: putative involvement of a P-glycoprotein transporter. Br J Pharmacol, 119, 1519-1524.
    • (1996) Br. J. Pharmacol. , vol.119 , pp. 1519-1524
    • Martel, F.1    Martins, M.J.2    Hipólito-Reis, C.3    Azevedo, I.4
  • 26
    • 0035166153 scopus 로고    scopus 로고
    • Apical uptake of organic cations by human intestinal Caco-2 cells: Putative involvement of ASF transporters
    • Martel F, Gründemann D, Calhau C & Schömig E (2001a) Apical uptake of organic cations by human intestinal Caco-2 cells: putative involvement of ASF transporters. Naunyn-Schmideberg's Arch Pharmacol, 363, 40-49.
    • (2001) Naunyn-Schmideberg's Arch. Pharmacol. , vol.363 , pp. 40-49
    • Martel, F.1    Gründemann, D.2    Calhau, C.3    Schömig, E.4
  • 28
    • 0022388516 scopus 로고
    • Dopamine but not norepinephrine or serotonin uptake inhibitors protect mice against neurotoxicity of MPTP
    • Melamed E, Rosenthal J, Cohen O, Globus M & Uzzan A (1985) Dopamine but not norepinephrine or serotonin uptake inhibitors protect mice against neurotoxicity of MPTP. Eur J Pharmacol, 116, 179-181.
    • (1985) Eur. J. Pharmacol. , vol.116 , pp. 179-181
    • Melamed, E.1    Rosenthal, J.2    Cohen, O.3    Globus, M.4    Uzzan, A.5
  • 29
    • 85031061455 scopus 로고
    • Graphpad Prism (version 1.0) San Diego: Graphpad Prism Software
    • Motulsky HJ, Spannard P & Neubig R (1994) Graphpad Prism (version 1.0). San Diego: Graphpad Prism Software.
    • (1994)
    • Motulsky, H.J.1    Spannard, P.2    Neubig, R.3
  • 30
    • 0031456987 scopus 로고    scopus 로고
    • Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites
    • Owens MJ, Morgan WN, Plott SJ & Nemeroff CB (1997) Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther, 283, 1305-1322.
    • (1997) J. Pharmacol. Exp. Ther. , vol.283 , pp. 1305-1322
    • Owens, M.J.1    Morgan, W.N.2    Plott, S.J.3    Nemeroff, C.B.4
  • 31
    • 0021856644 scopus 로고
    • Catecholamine-uptake inhibitors prevent the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mouse brain
    • Pileblad E & Carlssson A (1985) Catecholamine-uptake inhibitors prevent the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mouse brain. Neuropharmacology, 24, 689-692.
    • (1985) Neuropharmacology , vol.24 , pp. 689-692
    • Pileblad, E.1    Carlssson, A.2
  • 32
    • 0030011143 scopus 로고    scopus 로고
    • Functional expression of the plasma membrane serotonin transporter but not the vesicular monoamine transporter in human placental trophoblasts and choriocarcinoma cells
    • Prasad PD, Hoffmans BJ, Moe AJ, Smith CH, Leibach FH & Ganapathy V (1996) Functional expression of the plasma membrane serotonin transporter but not the vesicular monoamine transporter in human placental trophoblasts and choriocarcinoma cells. Placenta, 17, 201-207.
    • (1996) Placenta , vol.17 , pp. 201-207
    • Prasad, P.D.1    Hoffmans, B.J.2    Moe, A.J.3    Smith, C.H.4    Leibach, F.H.5    Ganapathy, V.6
  • 33
    • 0026684256 scopus 로고
    • Active transport of dopamine in human placental brush-border membrane vesicles
    • (Cell Physiol, 31)
    • Ramamoorthy S, Leibach FH, Mahesh VB & Ganapathy V (1992) Active transport of dopamine in human placental brush-border membrane vesicles. Am J Physiol, 262(Cell Physiol, 31), C1189-C1196.
    • (1992) Am. J. Physiol. , vol.262
    • Ramamoorthy, S.1    Leibach, F.H.2    Mahesh, V.B.3    Ganapathy, V.4
  • 36
    • 0027365495 scopus 로고
    • Cyanine-related compounds: A novel class of potent inhibitors of extraneuronal noradrenaline transport
    • Russ H, Sonna J, Keppler K, Baunach S & Schömig E (1993) Cyanine-related compounds: a novel class of potent inhibitors of extraneuronal noradrenaline transport. Naunyn-Schmiedeberg's Arch Pharmacol, 348, 458-465.
    • (1993) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.348 , pp. 458-465
    • Russ, H.1    Sonna, J.2    Keppler, K.3    Baunach, S.4    Schömig, E.5
  • 37
    • 0030009888 scopus 로고    scopus 로고
    • The extraneuronal transporter for monoamine transmitters exists in cells derived from human central nervous system glia
    • Russ H, Staudt K, Martel F, Gliese M & Schömig E (1996) The extraneuronal transporter for monoamine transmitters exists in cells derived from human central nervous system glia. Eur J Neurosci, 8, 1256-1264.
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 1256-1264
    • Russ, H.1    Staudt, K.2    Martel, F.3    Gliese, M.4    Schömig, E.5
  • 38
    • 0024349630 scopus 로고
    • Biochemical mechanism of action of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
    • Sayre LM (1989) Biochemical mechanism of action of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Toxicol Lett, 48, 121-149.
    • (1989) Toxicol. Lett. , vol.48 , pp. 121-149
    • Sayre, L.M.1
  • 39
    • 0034119972 scopus 로고    scopus 로고
    • Transporter-mediated release: A superfusion study on human embryonic kidney cells stably expressing the human serotonin transporter
    • Scholze P, Zwach J, Kattinger A, Pifl C, Singer EA & Sitte HH (2000) Transporter-mediated release: a superfusion study on human embryonic kidney cells stably expressing the human serotonin transporter. J Pharmacol Exp Ther, 293, 870-878.
    • (2000) J. Pharmacol. Exp. Ther. , vol.293 , pp. 870-878
    • Scholze, P.1    Zwach, J.2    Kattinger, A.3    Pifl, C.4    Singer, E.A.5    Sitte, H.H.6
  • 40
    • 0035037523 scopus 로고    scopus 로고
    • Quantitative analysis of inward and outward transport rates in cells stably expressing the cloned human serotonin transporter: Inconsistencies with the hypothesis of facilitated exchange diffusion
    • Sitte HH, Hiptmair B, Zwach J, Pifl C, Singer EA & Scholze P (2001) Quantitative analysis of inward and outward transport rates in cells stably expressing the cloned human serotonin transporter: inconsistencies with the hypothesis of facilitated exchange diffusion. Mol Pharmacol, 59, 1129-1137.
    • (2001) Mol. Pharmacol. , vol.59 , pp. 1129-1137
    • Sitte, H.H.1    Hiptmair, B.2    Zwach, J.3    Pifl, C.4    Singer, E.A.5    Scholze, P.6
  • 41
    • 0023234308 scopus 로고
    • The neurotoxins 1-methyl-4-phenylpyridinium and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine are substrates for the organic cation transporter in renal brush border membrane vesicles
    • Sokol PP, Holohan PD & Ross CR (1987) The neurotoxins 1-methyl-4-phenylpyridinium and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine are substrates for the organic cation transporter in renal brush border membrane vesicles. J Pharmacol Exp Ther, 242, 152-157.
    • (1987) J. Pharmacol. Exp. Ther. , vol.242 , pp. 152-157
    • Sokol, P.P.1    Holohan, P.D.2    Ross, C.R.3
  • 45
    • 0034212998 scopus 로고    scopus 로고
    • Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta. Biochim Biophys Acta
    • Wu X, George RL, Huang W, Wang H, Conway SJ, Leibach FH & Ganapathy V (2000) Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta. Biochim Biophys Acta, 1466, 315-327.
    • (2000) , vol.1466 , pp. 315-327
    • Wu, X.1    George, R.L.2    Huang, W.3    Wang, H.4    Conway, S.J.5    Leibach, F.H.6    Ganapathy, V.7
  • 46
    • 0031800792 scopus 로고    scopus 로고
    • Role of organic cation transporters in drug absorption and elimination
    • Zhang L, Brett CM & Giacomini KM (1998) Role of organic cation transporters in drug absorption and elimination. Ann Rev Pharmacol Toxicol, 38, 431-460.
    • (1998) Ann. Rev. Pharmacol. Toxicol. , vol.38 , pp. 431-460
    • Zhang, L.1    Brett, C.M.2    Giacomini, K.M.3
  • 47
    • 0034975789 scopus 로고    scopus 로고
    • Impaired activity of the extraneuronal monoamine transporter system known as uptake-2 in Orct3/Slc22a3-deficient mice
    • Zwart R, Verhaagh S, Buitelaar M, Popp-Snijders C & Barlow DP (2001) Impaired activity of the extraneuronal monoamine transporter system known as uptake-2 in Orct3/Slc22a3-deficient mice. Mol Cell Biol, 21, 4188-4196.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 4188-4196
    • Zwart, R.1    Verhaagh, S.2    Buitelaar, M.3    Popp-Snijders, C.4    Barlow, D.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.