Synthesis and antituberculosis activity of new phenylpyrrolo[1,2-a] quinoxalinylpyrrole carboxylic acid derivatives

Pharmacy and Pharmacology Communications

Volumn 4, Issue 1, 1998, Pages 33-38

  Guillon, J ^b   Dumoulin, H ^b   Dallemagne, P ^b   Reynolds, R ^a   Rault, S ^b  

^a SOUTHERN RESEARCH INSTITUTE   (United States)

^b UNIVERSITÉ DE CAEN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; RIFAMPICIN; TUBERCULOSTATIC AGENT;

CHEMICAL REACTION; CONFERENCE PAPER; CONTROLLED STUDY; DRUG SCREENING; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; REACTION ANALYSIS;

EID: 0031881413     PISSN: 14608081     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (17)

1. Alazard, J. P., Boyé, O., Gillet, B., Guénard, D., Beloeil, J. C., Thal, C. (1993) Composés interagissant avec la tubuline. Partie I: synthèse de phénylpyrroles ortho-ortho' substitués en rotation libre ou empêchée. Bull. Soc. Chim. Fr. 130: 779-787
2. Alazard, J. P., Millet-Paillusson, C., Guénard, D., Thal, C. (1996) Composés interagissant avec la tubuline. Partie II : synthèse de lactames tricycliques à squelette phénylpyrrole, analogues structuraux du rhazinilame. Bull. Soc. Chim. Fr. 133: 251-266
3. Barton, D. H. R., Zard, S. Z. (1985) A new synthesis of pyrroles from nitroalkenes. J. Chem. Soc., Chem. Commun. 6: 1098-1100
4. Cave, C., Galons, H., Miocque, M., Rinjard, P., Tran, G., Binet, P. (1990) Hydrazidones à action antihypertensive: étude des dichloroarylhydrazones acylées. Eur. J. Med. Chem. 25: 75-79
5. Curtius, T., Mohr, E. (1898) Ueberführung von nicotinsäure in β-amidopyridin. Chem. Ber. 31: 2493-2495
6. Dumoulin, H., Rault, S., Robba, M. (1995) Synthesis of new phenylpyrrolylpyrroles. J. Heterocyclic Chem. 32: 1703-1707
7. Dumoulin, H., Rault, S., Robba, M. (1996) Synthesis of phenylpyrrolylpyrroles. Part II. J. Heterocyclic Chem. 33: 255-258
8. Dumoulin, H., Rault, S., Robba, M. (1997) Synthesis of phenylpyrrolylpyrroles. Part III. J. Heterocyclic Chem. 34: 13-16
9. Guillon, J. (1996) Contribution à l'étude de Nouvelles Pyrrolo[1,2-a]quinoxalines: Potentiels Antagonistes Non-peptidques du Recépteur au Glucagon. PhD Thesis, University of Caen.
10. Inderleid, C. B., Nash, K. A. (1996) Antimycobacterial agents: in vitro susceptibility testing, spectra of activity, mechanisms of action and resistance, and assays for activity in biological fluids. In: Lorian, V. (ed.) Antibiotics in Laboratory Medicine. 4th edn, Williams & Wilkins, Baltimore, pp 127-175
11. Inderleid, C. B., Salfinger, M. (1995) Antimicrobial agents and susceptibility tests: mycobacteria. In: Murray, P. R., Baron, E. J., Pfaller, M. A., Tenover, F. C., Yolken, R. H. (eds) Manual of Clinical Microbiology. 6th edn, ASM Press, Washington, pp 1385-1404
12. Lash, T. D., Bellettini, J. R., Bastian, J. A., Couch, K. B. (1994) Synthesis of pyrroles from benzyl isocyanoacetate. Synthesis 2: 170-172
13. Mandell, G. L., Sande, M. A. (1990) Antimicrobial agents; drugs used in the chemotherapy of tuberculosis and leprosy. In: Gilman, A. G., Goodman, L. S., Rall, T. W., Nies, A. S., Taylor, P. (eds) The Pharmacological Basis of Therapeutics. 8th edn, Pergamon Press, New York, pp 1146-1164
14. Schöllkopf, U. (1977) Recent applications of α-metalated isocyanides in organic synthesis. Angew. Chem. Int. Ed. Engl. 16(6): 339-422
15. Shimoji, Y., Tomita, K., Hashimoto, T., Saito, F., Morisawa, Y., Mizuno, H., Yrikane, R., Koike, H. (1992) Synthesis and biological action of the aminotetrahydroisoquinocarbazoles and related compounds: a new class of compounds with antiarrhythmic activity. J. Med. Chem. 35: 816-822
16. Suzuki, M., Miyoshi, M., Matsumoto, K. (1974) A convenient synthesis of 3-substituted pyrrole-2,4-dicarboxylic acid esters. J. Org. Chem. 39: 1980
17. 4-androstènedione-3.17 par l'hydrazide nicotique. Bull. Soc. Chim. Fr. 12: 951-952