메뉴 건너뛰기




Volumn 12, Issue 8, 2006, Pages 2263-2273

Human mesenchymal stem cells induce T cell anergy and downregulate T cell allo-responses via the TH2 pathway: Relevance to tissue engineering human heart valves

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; HEART VALVE PROSTHESES; TISSUE; TISSUE CULTURE;

EID: 33750933744     PISSN: 10763279     EISSN: None     Source Type: Journal    
DOI: 10.1089/ten.2006.12.2263     Document Type: Article
Times cited : (192)

References (43)
  • 1
    • 0033803975 scopus 로고    scopus 로고
    • Cardiac valve replacement: A bioengineering approach
    • Korossis, S.A. et al. Cardiac valve replacement: a bioengineering approach. Biomed. Mater. Eng. 10, 83, 2000.
    • (2000) Biomed. Mater. Eng. , vol.10 , pp. 83
    • Korossis, S.A.1
  • 2
    • 20344395652 scopus 로고    scopus 로고
    • Will heart valve tissue engineering change the world?
    • Yacoub, M.H. et al. Will heart valve tissue engineering change the world? Nat. Clin. Pract. Cardiovasc. Med. 2, 60, 2005.
    • (2005) Nat. Clin. Pract. Cardiovasc. Med. , vol.2 , pp. 60
    • Yacoub, M.H.1
  • 3
    • 0037019337 scopus 로고    scopus 로고
    • Pluripotency of mesenchymal stem cells derived from adult marrow
    • Jiang, Y. et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418, 41, 2002.
    • (2002) Nature , vol.418 , pp. 41
    • Jiang, Y.1
  • 4
    • 0035574556 scopus 로고    scopus 로고
    • Baboon mesenchymal stem cells can be genetically modified to secrete human erythropoietin in vivo
    • Bartholomew, A. et al. Baboon mesenchymal stem cells can be genetically modified to secrete human erythropoietin in vivo. Hum. Gene Ther. 12, 1527, 2001.
    • (2001) Hum. Gene Ther. , vol.12 , pp. 1527
    • Bartholomew, A.1
  • 5
    • 0344961120 scopus 로고    scopus 로고
    • Murine marrow-derived mesenchymal stem cell: Isolation, in vitro expansion, and characterization
    • Meirelles, L.S. et al. Murine marrow-derived mesenchymal stem cell: isolation, in vitro expansion, and characterization. Br. J. Haematol. 123, 702, 2003.
    • (2003) Br. J. Haematol. , vol.123 , pp. 702
    • Meirelles, L.S.1
  • 6
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • Pittenger, M.F. et al. Multilineage potential of adult human mesenchymal stem cells. Science 284, 143, 1999.
    • (1999) Science , vol.284 , pp. 143
    • Pittenger, M.F.1
  • 7
    • 3142663241 scopus 로고    scopus 로고
    • Mesenchymal stem cells and their potential as cardiac therapeutics
    • Pittenger, M.F. et al. Mesenchymal stem cells and their potential as cardiac therapeutics. Circ. Res. 95, 9, 2004.
    • (2004) Circ. Res. , vol.95 , pp. 9
    • Pittenger, M.F.1
  • 8
    • 0037663711 scopus 로고    scopus 로고
    • Mesenchymal stem cell: Use and perspectives
    • Tocci, A. et al. Mesenchymal stem cell: use and perspectives. Hematol. J. 4, 92, 2003.
    • (2003) Hematol. J. , vol.4 , pp. 92
    • Tocci, A.1
  • 9
    • 0036831289 scopus 로고    scopus 로고
    • Stem cell medicine encounters the immune system
    • Bradley, J.A. et al. Stem cell medicine encounters the immune system. Nat. Rev. Immunol. 2, 859, 2002.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 859
    • Bradley, J.A.1
  • 10
    • 2342464992 scopus 로고    scopus 로고
    • Immunomodulatory functions of mesenchymal stem cells
    • Frank, M.H. et al. Immunomodulatory functions of mesenchymal stem cells. Lancet 363, 1411, 2004.
    • (2004) Lancet , vol.363 , pp. 1411
    • Frank, M.H.1
  • 11
    • 0036142769 scopus 로고    scopus 로고
    • Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo
    • Bartholomew, A. et al. Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo. Exp. Hematol. 30, 42, 2002.
    • (2002) Exp. Hematol. , vol.30 , pp. 42
    • Bartholomew, A.1
  • 12
    • 0038281370 scopus 로고    scopus 로고
    • Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into non-human primates
    • Devine, S.M. et al. Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into non-human primates. Blood 101, 2999, 2003.
    • (2003) Blood , vol.101 , pp. 2999
    • Devine, S.M.1
  • 13
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • Le Blanc, K. et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 363, 1439, 2004.
    • (2004) Lancet , vol.363 , pp. 1439
    • Le Blanc, K.1
  • 14
    • 0141886188 scopus 로고    scopus 로고
    • Veto-like activity of mesenchymal stem cells: Functional discrimination between cellular responses to alloantigens and recall antigens
    • Potian, J.A. et al. Veto-like activity of mesenchymal stem cells: functional discrimination between cellular responses to alloantigens and recall antigens. J. Immunol. 171, 3426, 2003.
    • (2003) J. Immunol. , vol.171 , pp. 3426
    • Potian, J.A.1
  • 15
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogencic immune cell responses
    • Aggarwal, S. et al. Human mesenchymal stem cells modulate allogencic immune cell responses. Blood 105, 1815, 2004.
    • (2004) Blood , vol.105 , pp. 1815
    • Aggarwal, S.1
  • 16
    • 0037442264 scopus 로고    scopus 로고
    • Suppression of allogencic T-cell proliferation by human marrow stromal cells: Implications in transplantation
    • Tse, W.T. et al. Suppression of allogencic T-cell proliferation by human marrow stromal cells: implications in transplantation. Transplantation 75, 389, 2003.
    • (2003) Transplantation , vol.75 , pp. 389
    • Tse, W.T.1
  • 17
    • 14944339174 scopus 로고    scopus 로고
    • Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness
    • Beyth, S. et al. Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness. Blood 105, 2214, 2005.
    • (2005) Blood , vol.105 , pp. 2214
    • Beyth, S.1
  • 18
    • 6344231170 scopus 로고    scopus 로고
    • Effect of cognate human CD4+ T cell and endothelial cell interactions upon chemokine production
    • Tay, S.S. et al. Effect of cognate human CD4+ T cell and endothelial cell interactions upon chemokine production. Transplantation 78, 987, 2004.
    • (2004) Transplantation , vol.78 , pp. 987
    • Tay, S.S.1
  • 19
    • 0035412822 scopus 로고    scopus 로고
    • Valve interstitial cells induce donor-specific T-cell anergy
    • Batten, P. et al. Valve interstitial cells induce donor-specific T-cell anergy. J. Thorac. Cardiovasc. Surg. 122, 129, 2001.
    • (2001) J. Thorac. Cardiovasc. Surg. , vol.122 , pp. 129
    • Batten, P.1
  • 20
    • 0030459866 scopus 로고    scopus 로고
    • Human and animal mesenchymal progenitor cells from bone marrow: Identification of serum for optimal selection and proliferation
    • Lennon, D.P. et al. Human and animal mesenchymal progenitor cells from bone marrow: identification of serum for optimal selection and proliferation. In Vitro Cell Dev. Biol. Anim. 32, 602, 1996.
    • (1996) In Vitro Cell Dev. Biol. Anim. , vol.32 , pp. 602
    • Lennon, D.P.1
  • 21
    • 0030977852 scopus 로고    scopus 로고
    • Immunogenicity of human heart valve endothelial cells and fibroblasts
    • Johnson, D.L. et al. Immunogenicity of human heart valve endothelial cells and fibroblasts. Transplant. Proc. 29, 984, 1997.
    • (1997) Transplant. Proc. , vol.29 , pp. 984
    • Johnson, D.L.1
  • 22
    • 0033984178 scopus 로고    scopus 로고
    • Phenotypic and functional characterization of interstitial cells from human heart valves, pericardium and skin
    • Taylor, P.M. et al. Phenotypic and functional characterization of interstitial cells from human heart valves, pericardium and skin. J. Heart Valve Dis. 9, 150, 2000.
    • (2000) J. Heart Valve Dis. , vol.9 , pp. 150
    • Taylor, P.M.1
  • 23
    • 0028199022 scopus 로고
    • Alloproliferative responses of purified CD4+ and CD8+ T cells to endothelial cells in the absence of contaminating accessory cells
    • Page, C.S. et al. Alloproliferative responses of purified CD4+ and CD8+ T cells to endothelial cells in the absence of contaminating accessory cells. Transplantation 57, 1628, 1994.
    • (1994) Transplantation , vol.57 , pp. 1628
    • Page, C.S.1
  • 24
    • 0029163138 scopus 로고
    • The primary alloresponse of human CD4+ T cells is dependent on B7 (CD80), augmented by CD58, but relatively uninfluenced by CD54 expression
    • Hargreaves, R. et al. The primary alloresponse of human CD4+ T cells is dependent on B7 (CD80), augmented by CD58, but relatively uninfluenced by CD54 expression. Int. Immunol. 7, 1505, 1995.
    • (1995) Int. Immunol. , vol.7 , pp. 1505
    • Hargreaves, R.1
  • 25
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • Di Nicola, M. et al. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 99, 3838, 2002.
    • (2002) Blood , vol.99 , pp. 3838
    • Di Nicola, M.1
  • 26
    • 0030300154 scopus 로고    scopus 로고
    • The complexities of T-cell co-stimulation: CD28 and beyond
    • Sperling, A.I. et al. The complexities of T-cell co-stimulation: CD28 and beyond. Immunol. Rev. 153, 155, 1996.
    • (1996) Immunol. Rev. , vol.153 , pp. 155
    • Sperling, A.I.1
  • 27
    • 3242794120 scopus 로고    scopus 로고
    • Differences in the kinetics, amplitude, and localization of ERK activation in anergy and priming revealed al the level of individual primary T cells by laser scanning cytometry
    • Adams, C.L. et al. Differences in the kinetics, amplitude, and localization of ERK activation in anergy and priming revealed al the level of individual primary T cells by laser scanning cytometry. J. Immunol. 173, 1579, 2004.
    • (2004) J. Immunol. , vol.173 , pp. 1579
    • Adams, C.L.1
  • 28
    • 0037167649 scopus 로고    scopus 로고
    • Tissue engineering of functional trileaflet heart valves from human marrow stromal cells
    • Hoerstrup, S.P. et al. Tissue engineering of functional trileaflet heart valves from human marrow stromal cells. Circulation 106, 1143, 2002.
    • (2002) Circulation , vol.106 , pp. 1143
    • Hoerstrup, S.P.1
  • 29
    • 0033678140 scopus 로고    scopus 로고
    • Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep
    • Liechty, K.W. et al. Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep. Nat. Med. 6, 1282, 2000.
    • (2000) Nat. Med. , vol.6 , pp. 1282
    • Liechty, K.W.1
  • 30
    • 17744365164 scopus 로고    scopus 로고
    • T cell responses to allogeneic human mesenchymal stem cells: Immunogenicity, tolerance, and suppression
    • Klyushnenkova, E. et al. T cell responses to allogeneic human mesenchymal stem cells: immunogenicity, tolerance, and suppression. J. Biomed. Sci. 12, 47, 2005.
    • (2005) J. Biomed. Sci. , vol.12 , pp. 47
    • Klyushnenkova, E.1
  • 31
    • 9444292844 scopus 로고    scopus 로고
    • Functional assessment and specific depletion of alloreactive human T cells using flow cytometry
    • Martins, S.L. et al. Functional assessment and specific depletion of alloreactive human T cells using flow cytometry. Blood 104, 3429, 2004.
    • (2004) Blood , vol.104 , pp. 3429
    • Martins, S.L.1
  • 32
    • 0038204193 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide
    • Krampera, M. et al. Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood 101, 3722, 2003.
    • (2003) Blood , vol.101 , pp. 3722
    • Krampera, M.1
  • 33
    • 0034192087 scopus 로고    scopus 로고
    • Donor MHC class II antigen is essential for induction of transplantation tolerance by bone marrow cells
    • Umemura, A. et al. Donor MHC class II antigen is essential for induction of transplantation tolerance by bone marrow cells. J. Immunol. 164, 4452, 2000.
    • (2000) J. Immunol. , vol.164 , pp. 4452
    • Umemura, A.1
  • 34
    • 0242410394 scopus 로고    scopus 로고
    • Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals
    • Djouad, F. et al. Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals. Blood 102, 3837, 2003.
    • (2003) Blood , vol.102 , pp. 3837
    • Djouad, F.1
  • 35
    • 2942595706 scopus 로고    scopus 로고
    • Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation
    • Meisel, R. et al. Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation. Blood 103, 4619, 2004.
    • (2004) Blood , vol.103 , pp. 4619
    • Meisel, R.1
  • 36
    • 0035903307 scopus 로고    scopus 로고
    • Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4+CD25+ regulatory T cells
    • Iellem, A. et al. Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4+CD25+ regulatory T cells. J. Exp. Med. 194, 847, 2001.
    • (2001) J. Exp. Med. , vol.194 , pp. 847
    • Iellem, A.1
  • 37
    • 85047692430 scopus 로고    scopus 로고
    • IL-10-producing and naturally occurring CD4(+) Tregs: Limiting collateral damage
    • O'garra, A. et al. IL-10-producing and naturally occurring CD4(+) Tregs: limiting collateral damage. J. Clin. Invest. 114, 1372, 2004.
    • (2004) J. Clin. Invest. , vol.114 , pp. 1372
    • O'Garra, A.1
  • 38
    • 4344683220 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit the expression of CD25 (interleukin-2 receptor) and CD38 on phyto-haemagglutinin-activated lymphocytes
    • Le Blanc, K. et al. Mesenchymal stem cells inhibit the expression of CD25 (interleukin-2 receptor) and CD38 on phyto-haemagglutinin-activated lymphocytes, Scand. J. Immunol. 60, 307, 2004.
    • (2004) Scand. J. Immunol. , vol.60 , pp. 307
    • Le Blanc, K.1
  • 39
    • 15244354286 scopus 로고    scopus 로고
    • Regulatory T cell lineage specification by the forkhead transcription factor foxp3
    • Fontenot, J.D. et al. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity 22, 329, 2005.
    • (2005) Immunity , vol.22 , pp. 329
    • Fontenot, J.D.1
  • 40
    • 0026320784 scopus 로고
    • Interleukin-1 receptor antagonist competitively inhibits the binding of interleukin-1 to the type II interleukin-1 receptor
    • Granowitz, E.V. et al. Interleukin-1 receptor antagonist competitively inhibits the binding of interleukin-1 to the type II interleukin-1 receptor. J. Biol. Chem. 266, 14147, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 14147
    • Granowitz, E.V.1
  • 41
    • 0035908946 scopus 로고    scopus 로고
    • Overexpression of interleukin-1 receptor antagonist provides cardioprotection against ischemia-reperfusion injury associated with reduction in apoptosis
    • Suzuki, K. et al. Overexpression of interleukin-1 receptor antagonist provides cardioprotection against ischemia-reperfusion injury associated with reduction in apoptosis. Circulation 104, 1308, 2001.
    • (2001) Circulation , vol.104 , pp. 1308
    • Suzuki, K.1
  • 42
    • 1242338093 scopus 로고    scopus 로고
    • The immunogenicity of human embryonic stem-derived cells
    • Drukker, M. et al. The immunogenicity of human embryonic stem-derived cells. Trends Biotechnol. 22, 136, 2004.
    • (2004) Trends Biotechnol. , vol.22 , pp. 136
    • Drukker, M.1
  • 43
    • 0141484485 scopus 로고    scopus 로고
    • HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells
    • Le Blanc, K. et al. HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells. Exp. Hematol. 31, 890, 2003.
    • (2003) Exp. Hematol. , vol.31 , pp. 890
    • Le Blanc, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.