Oxidative inactivation of reduced NADP-generating enzymes in E. coli: Iron-dependent inactivation with affinity cleavage of NADP-isocitrate dehydrogenase

Archives of Microbiology

Volumn 186, Issue 5, 2006, Pages 385-392

  Murakami, Keiko ^a   Tsubouchi, Ryoko ^a   Fukayama, Minoru ^a   Ogawa, Tadashi ^a   Yoshino, Masataka ^a  

^a AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Affinity cleavage; Iron; Metal binding; NADP isocitrate dehydrogenase; Reactive oxygen species

Indexed keywords

ALANINE; ASCORBIC ACID; ASPARTIC ACID; CATALASE; FERROUS ION; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLYOXYLIC ACID; HYDROGEN PEROXIDE; HYDROXYL RADICAL; IRON; ISOCITRATE DEHYDROGENASE (NADP); MAGNESIUM; MANGANESE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUPEROXIDE; TYROSINE;

AEROBIC BACTERIA; ANTIOXIDANT ACTIVITY; ARTICLE; BACTERIAL GROWTH; BINDING SITE; CITRIC ACID CYCLE; CONTROLLED STUDY; ENZYME INACTIVATION; ENZYME METABOLISM; ESCHERICHIA COLI; FRAGMENTATION REACTION; INHIBITION KINETICS; METAL BINDING; MOLECULAR WEIGHT; NONHUMAN; OXIDATION KINETICS; PEPTIDE SYNTHESIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; REDUCTION KINETICS; SEQUENCE ANALYSIS;

BINDING SITES; CULTURE MEDIA; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ESCHERICHIA COLI K12; ESCHERICHIA COLI PROTEINS; FERROUS COMPOUNDS; GLUCOSEPHOSPHATE DEHYDROGENASE; ISOCITRATE DEHYDROGENASE; MASS SPECTROMETRY; MOLECULAR WEIGHT; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; REACTIVE OXYGEN SPECIES;

EID: 33750740392     PISSN: 03028933     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00203-006-0153-1     Document Type: Article

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