Antioxidant function of cytosolic sources of NADPH in yeast

Free Radical Biology and Medicine

Volumn 31, Issue 6, 2001, Pages 832-843

  Minard, Karyl I ^a   McAlister Henn, Lee ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Catalase; Free radicals; Glucose 6 phosphate dehydrogenase; Isocitrate dehydrogenase; NADPH; Oxidative stress; Peroxidase

Indexed keywords

ACETIC ACID; CATALASE; CELL NUCLEUS DNA; CYTOCHROME C PEROXIDASE; DITHIOTHREITOL; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; HYDROGEN PEROXIDE; ISOCITRATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OLEIC ACID; OXIDIZING AGENT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; THIOL;

ANTIOXIDANT ACTIVITY; ARTICLE; CATALYSIS; CELL COUNT; CELL GROWTH; CELL LEVEL; CELL METABOLISM; CELL VIABILITY; CONTROLLED STUDY; CYTOSOL; DNA STRAND BREAKAGE; ENZYME INACTIVATION; FUNGUS MUTANT; GENE DISRUPTION; GENETIC CODE; GROWTH RATE; HAPLOIDY; MATING; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; YEAST;

ANTIOXIDANTS; CATALASE; CELL SURVIVAL; CYTOCHROME-C PEROXIDASE; CYTOSOL; GLUCOSEPHOSPHATE DEHYDROGENASE; HYDROGEN PEROXIDE; ISOCITRATE DEHYDROGENASE; MITOCHONDRIA; MUTAGENESIS; NADP; OXIDANTS; OXIDATIVE STRESS; PHENOTYPE; SACCHAROMYCES CEREVISIAE; SULFHYDRYL COMPOUNDS; TIME FACTORS;

EID: 0035884739     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00666-9     Document Type: Article

References (56)

1. Formation, prevention, and repair of DNA damage by iron/hydrogen peroxide
2. Protein oxidation in aging, disease, and oxidative stress
3. Oxidative stress, caloric restriction, and aging
4. Oxidative stress responses of the yeast Saccharomyces cerevisiae
5. Stress-controlled transcription factors, stress-induced genes and stress tolerance in budding yeast
6. The copper, zinc-superoxide dismutase gene of Saccharomyces cerevisiae: Cloning, sequencing and biological activity
7. Nucleotide sequence analysis of the nuclear gene coding for manganese superoxide dismutase of yeast mitochondria, a gene previously assumed to code for the Rieske iron-sulphur protein
8. Nucleotide sequence of the yeast nuclear gene for cytochrome c peroxidase protein: Functional implications of the presequence of protein transport into mitochondria
9. Nucleotide sequence of Saccharomyces cerevisiae CTT1 gene and deduced amino acid sequence of catalase T
10. Sequence of the yeast Saccharomyces cerevisiae CTA1 gene and amino-acid sequence of catalase A derived from it
11. Genetic analysis of glutathione peroxidase in oxidative stress response of Saccharomyces cerevisiae
12. Distinct physiological functions of thiol peroxidase isoenzymes in Saccharomyces cerevisiae
13. 2 stimulon in Saccharomyces cerevisiae
14. Yeast glutathione reductase is required for protection against oxidative stress and is a target gene for YAP-1 transcriptional regulation
15. Thioredoxin reductase-dependent inhibition of MCB cell cycle box activity in Saccharomyces cerevisiae
16. The yeast peptide-methionine sulfoxide reductase functions as an antioxidant in vivo
17. Overexpression of peptide-methionine sulfoxide reductase in Saccharomyces cerevisiae and human T cells provides them with high resistance to oxidative stress
18. Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae. Mitochondrial production of toxic oxygen species in vivo
19. Effect of Cu,Zn superoxide dismutase disruption mutation on replicative senescence in Saccharomyces cerevisiae
20. The influence of oxygen toxicity on yeast mother cell-specific aging
21. Dependence of peroxisomal β-oxidation on cytosolic sources of NADPH
22. Isolation and characterization of the ZWF1 gene of Saccharomyces cerevisiae, encoding glucose-6-phosphate dehydrogenase
23. Sterile host yeast (Shy): A eucaryotic system of biological containment for recombinant DNA experiments
24. Analysis and manipulation of yeast mitochondrial genes
25. Isolation, characterization, and disruption of the yeast gene encoding cytosolic NADP-specific isocitrate dehydrogenase
26. +-specific isocitrate dehydrogenase in Saccharomyces cerevisiae
27. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
28. New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae
29. Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast
30. Improved method for high efficiency transformation of intact yeast cells
31. A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli
32. Function and expression of yeast mitochondrial NAD- and NADP-specific isocitrate dehydrogenases
33. Glucose-6-phosphate dehydrogenase (crystalline) from brewer's yeast
34. A yeast mutant lacking thiol-dependent protector protein is hypersensitive to menadione
35. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
36. Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays
37. Relationship of actin and tubulin distribution to bud growth in wild-type and morphogenetic-mutant Saccharomyces cerevisiae
38. A yeast mutant showing diagnostic markers of early and late apoptosis
39. Oxygen stress: A regulator of apoptosis in yeast
40. The molecular defences against reactive oxygen species in yeast
41. Identification of the structural gene for glucose-6-phosphate dehydrogenase in yeast. Inactivation leads to a nutritional requirement for organic sulfur
42. Saccharomyces cerevisiae contains two functional citrate synthase genes
43. Isolation and expression of the gene encoding yeast mitochondrial malate dehydrogenase
44. +-dependent isocitrate dehydrogenase: Cloning, nucleotide sequence, and disruption of the IDH2 gene from Saccharomyces cerevisiae
45. Association of glyoxylate and beta-oxidation enzymes with peroxisomes of Saccharomyces cerevisiae
46. Free radical generated in yeast by the Salmonella test-negative carcinogens benzene, urethane, thiourea, and auramine O
47. Mitochondrial superoxide decreases yeast survival in stationary phase
48. The mitochondrial cytochrome c peroxidase Ccp1 of Saccharomyces cerevisiae is involved in conveying an oxidative stress signal to the transcription factor Pos9 (Skn7)
49. Oxidative stress promotes specific protein damage in Saccharomyces cerevisiae
50. A mutation in a mitochondrial ABC transporter results in mitochondrial dysfunction through oxidative damage of mitochondrial DNA
51. Direct detection of yeast mutants with reduced viability on plates by Erythrosine B staining
52. Oxidative stress during aging of stationary cultures of the yeast Saccharomyces cerevisiae
53. Molecular mechanisms of yeast longevity
54. Loss of transcriptional silencing causes sterility in old mother cells of Saccharomyces cerevisiae
55. Aged mother cells of Saccharomyces cerevisiae show markers of oxidative stress and apoptosis
56. β-Oxidation of fatty acids in mitochondria, peroxisomes, and bacteria: A century of continued progress