Identification of a 4-mer peptide inhibitor that effectively blocks the polymerization of pathogenic Z α1-antitrypsin

American Journal of Respiratory Cell and Molecular Biology

Volumn 35, Issue 5, 2006, Pages 540-548

  Chang, Yi Pin ^b   Mahadeva, Ravi ^b   Chang, Wun Shaing W ^b   Shukla, Anshuman ^b   Dafforn, Tim R ^b   Chu, Yen Ho ^a  

^a NATIONAL CHUNG CHENG UNIVERSITY   (Taiwan)

^b NONE

Author keywords

1 Antitrypsin; 1 Proteinase inhibitor; Alanine scanning; Polymerization; Serpin

Indexed keywords

ALANINE; ALPHA 1 ANTITRYPSIN; PROTEINASE INHIBITOR; SERINE PROTEINASE INHIBITOR; SYNTHETIC PEPTIDE;

ARTICLE; EMPHYSEMA; HUMAN; LUNG DISEASE; PATHOGENESIS; POLYMERIZATION; PROTEIN BINDING; PROTEIN FOLDING;

ALPHA 1-ANTITRYPSIN; AMINO ACID SEQUENCE; HUMANS; MODELS, MOLECULAR; PEPTIDES; POLYMERS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN ISOFORMS; SERINE PROTEINASE INHIBITORS;

EID: 33750725161     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2005-0207OC     Document Type: Article

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