N-nitroso-fenfluramine hepatotoxicity resembling chronic hepatitis [1]

Journal of Gastroenterology and Hepatology (Australia)

Volumn 18, Issue 8, 2003, Pages 999-1000

  Kanda, Tatsuo ^a,b   Yokosuka, Osamu ^a   Tada, Motohisa ^a   Kurihara, Tomoko ^a   Yoshida, Setsuko ^c   Suzuki, Yutaka ^c   Nagao, Keiichi ^b   Saisho, Hiromitsu ^a  

^a CHIBA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c Yachiyo Central Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ANTINUCLEAR ANTIBODY; ASPARTATE AMINOTRANSFERASE; BE PETITE; FENFLURAMINE; HERBACEOUS AGENT; IMMUNOGLOBULIN E; N NITROSOFENFLURAMINE; SMOOTH MUSCLE ANTIBODY; UNCLASSIFIED DRUG;

ADULT; CASE REPORT; CHRONIC HEPATITIS; CLINICAL FEATURE; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; DISEASE COURSE; FATIGUE; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; JAPAN; JAUNDICE; LABORATORY TEST; LETTER; LIVER BIOPSY; LIVER FUNCTION TEST; LIVER HISTOLOGY; LIVER TOXICITY; LYMPHOCYTE TRANSFORMATION TEST; NAUSEA; PRIORITY JOURNAL; SEROLOGY; TOXIC HEPATITIS; TREATMENT OUTCOME; VOMITING; WEIGHT REDUCTION;

EID: 0042855185     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1746.2003.03074.x     Document Type: Letter

References (5)

1. Kanda T, Yokosuka O, Okada O, Suzuki Y, Saisho H. Severe hepaototoxicity associated with Chinese diet product 'Onshidou-Genbi-Kounou'. J. Gastroenterol. Hepatol. 2003; 18: 354-55.
2. Japanese Ministry of Health, Labour and Welfare. About the Detection of N-nitroso-fenfluramine (in Japanese). Accessed 27 November, 2002. Available from: URL: http://www.mhlw.go.Jp/houdou/2002/07/h0719-3.html
3. Marcus DM, Grollman AP. Botanical medicines - the need for new regulations. N. Engl. J. Med. 2002;25:2073-6.
4. Stedman C. Herbal hepatotoxicity. Semin. Liver Dis. 2002; 22:195-206.
5. Maddrey WC, Boitnott JK. Drug-induced chronic liver disease. Gastroenterology 1977;72:1348-53.