-
1
-
-
13844289422
-
Intratumoral molecular or genetic markers as predictors of clinical outcome with chemotherapy in colorectal cancer
-
Grem JL: Intratumoral molecular or genetic markers as predictors of clinical outcome with chemotherapy in colorectal cancer. Semin Oncol 32: 120-127, 2005.
-
(2005)
Semin Oncol
, vol.32
, pp. 120-127
-
-
Grem, J.L.1
-
2
-
-
0030883708
-
Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin
-
Leichman CG, Lenz HJ, Leichman L, Danenberg K, Baranda J, Groshen S, Boswell W, Metzger R, Tan M and Danenberg PV: Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin. J Clin Oncol 15: 3223-3229, 1997.
-
(1997)
J Clin Oncol
, vol.15
, pp. 3223-3229
-
-
Leichman, C.G.1
Lenz, H.J.2
Leichman, L.3
Danenberg, K.4
Baranda, J.5
Groshen, S.6
Boswell, W.7
Metzger, R.8
Tan, M.9
Danenberg, P.V.10
-
3
-
-
0031722179
-
High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with non-response to 5-fluorouracil
-
Metzger R, Danenberg K, Leichman CG, Salonga D, Schwartz EL, Wadler S, Lenz HJ, Groshen S, Leichman L and Danenberg PV: High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with non-response to 5-fluorouracil. Clin Cancer Res 4: 2371-2376, 1998.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2371-2376
-
-
Metzger, R.1
Danenberg, K.2
Leichman, C.G.3
Salonga, D.4
Schwartz, E.L.5
Wadler, S.6
Lenz, H.J.7
Groshen, S.8
Leichman, L.9
Danenberg, P.V.10
-
4
-
-
0034048729
-
Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase and thymidine phosphorylase
-
Salonga D, Danenberg KD, Johnson M, Metzger R, Groshen S, Tsao-Wei DD, Lenz HJ, Leichman CG, Leichman L, Diasio RB and Danenberg PV: Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase and thymidine phosphorylase. Clin Cancer Res 6: 1322-1327, 2000.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1322-1327
-
-
Salonga, D.1
Danenberg, K.D.2
Johnson, M.3
Metzger, R.4
Groshen, S.5
Tsao-Wei, D.D.6
Lenz, H.J.7
Leichman, C.G.8
Leichman, L.9
Diasio, R.B.10
Danenberg, P.V.11
-
6
-
-
0033975032
-
Thymidilate synthase and p53 primary tumor expression as predictive factors for advanced colorectal cancer patients
-
Paradiso A, Simone G, Petroni S, Leone B, Vallejo C, Lacava J, Romero A, Machiavelli M, De Lena M, Allegra CJ and Johnston PG: Thymidilate synthase and p53 primary tumor expression as predictive factors for advanced colorectal cancer patients. Br J Cancer 82: 560-567, 2000.
-
(2000)
Br J Cancer
, vol.82
, pp. 560-567
-
-
Paradiso, A.1
Simone, G.2
Petroni, S.3
Leone, B.4
Vallejo, C.5
Lacava, J.6
Romero, A.7
Machiavelli, M.8
De Lena, M.9
Allegra, C.J.10
Johnston, P.G.11
-
7
-
-
0031053520
-
Lack of correlation between thymidylate synthase levels in primary colorectal tumours and subsequent response to chemotherapy
-
Findlay MP, Cunningham D, Morgan G, Clinton S, Hardcastle A and Aherne GW: Lack of correlation between thymidylate synthase levels in primary colorectal tumours and subsequent response to chemotherapy. Br J Cancer 75: 903-909, 1997.
-
(1997)
Br J Cancer
, vol.75
, pp. 903-909
-
-
Findlay, M.P.1
Cunningham, D.2
Morgan, G.3
Clinton, S.4
Hardcastle, A.5
Aherne, G.W.6
-
8
-
-
0034486207
-
Thymidylate synthase protein expression in primary colorectal cancer compared with the corresponding distant metastases and relationship with the clinical response to 5-fluorouracil
-
Aschele C, Debernardis D, Tunesi G, Maley F and Sobrero A: Thymidylate synthase protein expression in primary colorectal cancer compared with the corresponding distant metastases and relationship with the clinical response to 5-fluorouracil. Clin Cancer Res 6: 4797-4802, 2000.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4797-4802
-
-
Aschele, C.1
Debernardis, D.2
Tunesi, G.3
Maley, F.4
Sobrero, A.5
-
9
-
-
0037364351
-
Thymidylate synthase protein expression in primary colorectal cancer: Lack of correlation with outcome and response to fluorouracil in metastatic disease sites
-
Johnston PG, Benson AB III, Catalano P, Rao MS, O'Dwyer PJ and Allegra CJ: Thymidylate synthase protein expression in primary colorectal cancer: lack of correlation with outcome and response to fluorouracil in metastatic disease sites. J Clin Oncol 21: 815-819, 2003.
-
(2003)
J Clin Oncol
, vol.21
, pp. 815-819
-
-
Johnston, P.G.1
Benson III, A.B.2
Catalano, P.3
Rao, M.S.4
O'Dwyer, P.J.5
Allegra, C.J.6
-
10
-
-
0035522656
-
Thymidylate synthase gene expression in primary colorectal cancer and metastatic sites
-
Yamada H, Ichikawa W, Uetake H, Shirota Y, Nihei Z, Sugihara K and Hirayama R: Thymidylate synthase gene expression in primary colorectal cancer and metastatic sites. Clin Colorectal Cancer 1: 169-174, 2001.
-
(2001)
Clin Colorectal Cancer
, vol.1
, pp. 169-174
-
-
Yamada, H.1
Ichikawa, W.2
Uetake, H.3
Shirota, Y.4
Nihei, Z.5
Sugihara, K.6
Hirayama, R.7
-
11
-
-
0036209688
-
Differential expression of cell cycle and apoptosis related proteins in colorectal mucosa, primary colon tumours and liver metastases
-
Backus HH, van Groeningen CJ, Vos W, Dukers DF, Bloemena E, Wouters D, Pinedo HM and Peters GJ: Differential expression of cell cycle and apoptosis related proteins in colorectal mucosa, primary colon tumours and liver metastases. J Clin Pathol 55: 206-211, 2002.
-
(2002)
J Clin Pathol
, vol.55
, pp. 206-211
-
-
Backus, H.H.1
Van Groeningen, C.J.2
Vos, W.3
Dukers, D.F.4
Bloemena, E.5
Wouters, D.6
Pinedo, H.M.7
Peters, G.J.8
-
12
-
-
2142705747
-
Gene expression of 5-fluorouracil metabolic enzymes in primary colorectal cancer and corresponding liver metastasis
-
Inokuchi M, Uetake H, Shirota Y, Yamada H, Tajima M and Sugihara K: Gene expression of 5-fluorouracil metabolic enzymes in primary colorectal cancer and corresponding liver metastasis. Cancer Chemother Pharmacol 53: 391-396, 2004.
-
(2004)
Cancer Chemother Pharmacol
, vol.53
, pp. 391-396
-
-
Inokuchi, M.1
Uetake, H.2
Shirota, Y.3
Yamada, H.4
Tajima, M.5
Sugihara, K.6
-
13
-
-
0036064015
-
Intratumoral dihydropyrimidine dehydrogenase messenger RNA level reflects tumor progression in human colorectal cancer
-
Shirota Y, Ichikawa W, Uetake H, Yamada H, Nihei Z and Sugihara K: Intratumoral dihydropyrimidine dehydrogenase messenger RNA level reflects tumor progression in human colorectal cancer. Ann Surg Oncol 9: 599-603, 2002.
-
(2002)
Ann Surg Oncol
, vol.9
, pp. 599-603
-
-
Shirota, Y.1
Ichikawa, W.2
Uetake, H.3
Yamada, H.4
Nihei, Z.5
Sugihara, K.6
-
14
-
-
0034108036
-
Dihydropyrimidine dehydrogenase activity in normal, inflammatory and tumour tissues of colon and liver in humans
-
Guimbaud R, Guichard S, Dusseau C, Bertrand V, Aparicio T, Lochon I, Chatelut E, Couturier D, Bugat R, Chaussade S and Canal P: Dihydropyrimidine dehydrogenase activity in normal, inflammatory and tumour tissues of colon and liver in humans. Cancer Chemother Pharmacol 45: 477-482, 2000.
-
(2000)
Cancer Chemother Pharmacol
, vol.45
, pp. 477-482
-
-
Guimbaud, R.1
Guichard, S.2
Dusseau, C.3
Bertrand, V.4
Aparicio, T.5
Lochon, I.6
Chatelut, E.7
Couturier, D.8
Bugat, R.9
Chaussade, S.10
Canal, P.11
-
15
-
-
0036511176
-
Primary colorectal tumour is not an accurate predictor of thymidylate synthase in lymph node metastasis
-
Marsh S, McKay JA, Curran S, Murray GI, Cassidy J and McLeod HL: Primary colorectal tumour is not an accurate predictor of thymidylate synthase in lymph node metastasis. Oncol Rep 9: 231-234, 2002.
-
(2002)
Oncol Rep
, vol.9
, pp. 231-234
-
-
Marsh, S.1
McKay, J.A.2
Curran, S.3
Murray, G.I.4
Cassidy, J.5
McLeod, H.L.6
-
16
-
-
0030726659
-
Laser capture microdissection: Molecular analysis of tissue
-
Bonner RF, Emmert-Buck M, Cole K, Pohida T, Chuaqui R, Goldstein S and Liotta LA: Laser capture microdissection: molecular analysis of tissue. Science 278: 1481-1483, 1997.
-
(1997)
Science
, vol.278
, pp. 1481-1483
-
-
Bonner, R.F.1
Emmert-Buck, M.2
Cole, K.3
Pohida, T.4
Chuaqui, R.5
Goldstein, S.6
Liotta, L.A.7
-
17
-
-
0034146097
-
Telomerase reverse transcriptase expression is increased early in the Barrett's metaplasia, dysplasia, adenocarcinoma sequence
-
Lord RV, Salonga D, Danenberg KD, Peters JH, De Meester TR, Park JM, Johansson J, Skinner KA, Chandrasoma P, De Meester SR, Bremner CG, Tsai PI and Danenberg PV: Telomerase reverse transcriptase expression is increased early in the Barrett's metaplasia, dysplasia, adenocarcinoma sequence. J Gastrointest Surg 4: 135-142, 2000.
-
(2000)
J Gastrointest Surg
, vol.4
, pp. 135-142
-
-
Lord, R.V.1
Salonga, D.2
Danenberg, K.D.3
Peters, J.H.4
De Meester, T.R.5
Park, J.M.6
Johansson, J.7
Skinner, K.A.8
Chandrasoma, P.9
De Meester, S.R.10
Bremner, C.G.11
Tsai, P.I.12
Danenberg, P.V.13
-
19
-
-
4243180460
-
Interobserver reproducibility of immunohistochemical HER-2/neu evaluation in human breast cancer: The real-world experience
-
Italian Network for Quality Assurance of Tumor Biomarkers (INQAT) Group
-
Italian Network for Quality Assurance of Tumor Biomarkers (INQAT) Group: Interobserver reproducibility of immunohistochemical HER-2/neu evaluation in human breast cancer: the real-world experience. Int J Biol Markers 19: 147-154, 2004.
-
(2004)
Int J Biol Markers
, vol.19
, pp. 147-154
-
-
-
20
-
-
0032524104
-
Landscaping the cancer terrain
-
Kinzler K and Vogelstein B: Landscaping the cancer terrain. Science 279: 1036-1037, 1998.
-
(1998)
Science
, vol.279
, pp. 1036-1037
-
-
Kinzler, K.1
Vogelstein, B.2
-
21
-
-
0035888165
-
Thymidine phosphorylase and dihydropyrimidine dehydrogenase protein expression in colorectal cancer
-
Collie-Duguid ES, Johnston SJ, Boyce L, Smith N, Cowieson A, Cassidy J, Murray GI and McLeod HL: Thymidine phosphorylase and dihydropyrimidine dehydrogenase protein expression in colorectal cancer. Int J Cancer 94: 297-301, 2001.
-
(2001)
Int J Cancer
, vol.94
, pp. 297-301
-
-
Collie-Duguid, E.S.1
Johnston, S.J.2
Boyce, L.3
Smith, N.4
Cowieson, A.5
Cassidy, J.6
Murray, G.I.7
McLeod, H.L.8
-
22
-
-
0032127244
-
Design of a novel oral fluoropyrimidine carbamate, caecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concnetrted in human liver and cancer tissue
-
Miwa M, Ura M, Nishida M, Swada N, Ishikawa T, Mori K, Shimma N, Umeda I and Ishitsuka H: Design of a novel oral fluoropyrimidine carbamate, caecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concnetrted in human liver and cancer tissue. Eur J Biochem 34: 1274-1281, 1998.
-
(1998)
Eur J Biochem
, vol.34
, pp. 1274-1281
-
-
Miwa, M.1
Ura, M.2
Nishida, M.3
Swada, N.4
Ishikawa, T.5
Mori, K.6
Shimma, N.7
Umeda, I.8
Ishitsuka, H.9
-
23
-
-
0034548797
-
Gene expression for dihydropyrimidine dehydrogenase and thymidine phosphorylase influences outcome in epithelial ovarian cancer
-
Fujiwaki R, Hata K, Nakayama K, Fukumoto M and Miyazaki K: Gene expression for dihydropyrimidine dehydrogenase and thymidine phosphorylase influences outcome in epithelial ovarian cancer. J Clin Oncol 18: 3946-3951, 2000.
-
(2000)
J Clin Oncol
, vol.18
, pp. 3946-3951
-
-
Fujiwaki, R.1
Hata, K.2
Nakayama, K.3
Fukumoto, M.4
Miyazaki, K.5
-
24
-
-
16544386812
-
Comparative analysis of thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in gastric and colorectal cancers
-
Hotta T, Taniguchi K, Kobayashi Y, Johata K, Sahara M, Naka T, Watanabe T, Ochiai M, Tanimura H and Tsubota YT: Comparative analysis of thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in gastric and colorectal cancers. Oncol Rep 11: 1045-1051, 2004.
-
(2004)
Oncol Rep
, vol.11
, pp. 1045-1051
-
-
Hotta, T.1
Taniguchi, K.2
Kobayashi, Y.3
Johata, K.4
Sahara, M.5
Naka, T.6
Watanabe, T.7
Ochiai, M.8
Tanimura, H.9
Tsubota, Y.T.10
-
25
-
-
0033955853
-
Thymidine phosphorylase expression in tumor stroma of uterine cervical carcinomas: Histological features and microvessel density
-
Tang W, Wang X, Utsunomiya H, Nakamuta Y, Yang Q, Zhang Q, Zhou G, Tsubota Y, Mabuchi Y, Li L and Kakudo K: Thymidine phosphorylase expression in tumor stroma of uterine cervical carcinomas: histological features and microvessel density. Cancer Lett 148: 153-159, 2000.
-
(2000)
Cancer Lett
, vol.148
, pp. 153-159
-
-
Tang, W.1
Wang, X.2
Utsunomiya, H.3
Nakamuta, Y.4
Yang, Q.5
Zhang, Q.6
Zhou, G.7
Tsubota, Y.8
Mabuchi, Y.9
Li, L.10
Kakudo, K.11
-
26
-
-
17144447030
-
Expression of platelet-derived endothelial cell growth factor correlates with good prognosis in patients with colorectal carcinoma
-
Saito S, Tsuno N, Nagawa H, Sunami E, Zhengxi J, Osada T, Kitayama J, Shibata Y, Tsuruo T and MutoT: Expression of platelet-derived endothelial cell growth factor correlates with good prognosis in patients with colorectal carcinoma. Cancer 88: 42-49, 2000.
-
(2000)
Cancer
, vol.88
, pp. 42-49
-
-
Saito, S.1
Tsuno, N.2
Nagawa, H.3
Sunami, E.4
Zhengxi, J.5
Osada, T.6
Kitayama, J.7
Shibata, Y.8
Tsuruo, T.9
Muto, T.10
-
27
-
-
0035137358
-
Immunohistochemical localization of platelet-derived endothelial cell growth factor expression and its relation to angiogenesis in prostate
-
Okada K, Yokoyama K, Okihara K, Ukimura O, Kojima M, Miki T and Takamatsu T: Immunohistochemical localization of platelet-derived endothelial cell growth factor expression and its relation to angiogenesis in prostate. Urology 57: 376-381, 2001.
-
(2001)
Urology
, vol.57
, pp. 376-381
-
-
Okada, K.1
Yokoyama, K.2
Okihara, K.3
Ukimura, O.4
Kojima, M.5
Miki, T.6
Takamatsu, T.7
|