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Volumn 228, Issue 2-3, 2006, Pages 269-279

Clotrimazole, an antifungal drug possessing diverse actions, increases the vulnerability to cadmium in lymphocytes dissociated from rat thymus

Author keywords

Cadmium; Clotrimazole; Cytotoxicity; Lead; Lymphocyte; Mercury

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ANTIFUNGAL AGENT; CADMIUM; CADMIUM CHLORIDE; CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM ION; CLOTRIMAZOLE; FLUORESCENT DYE; HEAVY METAL; LEAD CHLORIDE; MEMBRANE PHOSPHOLIPID; MERCURY CHLORIDE; PHOSPHATIDYLSERINE;

EID: 33750683689     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2006.09.007     Document Type: Article
Times cited : (6)

References (49)
  • 3
    • 0027275040 scopus 로고
    • + transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivatives
    • + transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivatives. J. Clin. Invest. 92 (1993) 520-526
    • (1993) J. Clin. Invest. , vol.92 , pp. 520-526
    • Brugnara, C.1    de Franceschi, L.2    Alper, S.L.3
  • 4
    • 0029658379 scopus 로고    scopus 로고
    • 2-induced changes in cell viability and cellular nonprotein thiol level of dissociated rat thymocytes
    • 2-induced changes in cell viability and cellular nonprotein thiol level of dissociated rat thymocytes. Jpn. J. Pharmacol. 71 (1996) 299-305
    • (1996) Jpn. J. Pharmacol. , vol.71 , pp. 299-305
    • Chikahisa, L.1    Oyama, Y.2    Okazaki, E.3    Noda, K.4
  • 8
    • 0026508561 scopus 로고
    • Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages
    • Fadok V.A., Voelker D.R., Campbell P.A., Cohen J.J., Bratton D.L., and Hensen P.M. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J. Immunol. 148 (1992) 2207-2216
    • (1992) J. Immunol. , vol.148 , pp. 2207-2216
    • Fadok, V.A.1    Voelker, D.R.2    Campbell, P.A.3    Cohen, J.J.4    Bratton, D.L.5    Hensen, P.M.6
  • 12
    • 0036045404 scopus 로고    scopus 로고
    • The antifungal antibiotic clotrimazole alters calcium homeostasis of leukemic lymphoblasts and induces apoptosis
    • Ito C., Tecchio C., Coustan-Smith E., Suzuki T., Behm F.G., Raimondi S.C., Pui C.H., and Campana D. The antifungal antibiotic clotrimazole alters calcium homeostasis of leukemic lymphoblasts and induces apoptosis. Leukemia 16 (2002) 1344-1352
    • (2002) Leukemia , vol.16 , pp. 1344-1352
    • Ito, C.1    Tecchio, C.2    Coustan-Smith, E.3    Suzuki, T.4    Behm, F.G.5    Raimondi, S.C.6    Pui, C.H.7    Campana, D.8
  • 14
    • 5744253112 scopus 로고    scopus 로고
    • 2-terminal kinase (JNK) and apoptosis in response to cadmium in murine macrophages
    • 2-terminal kinase (JNK) and apoptosis in response to cadmium in murine macrophages. Toxicol. Sci. 81 (2004) 518-527
    • (2004) Toxicol. Sci. , vol.81 , pp. 518-527
    • Kim, J.1    Sharma, R.P.2
  • 15
    • 0026666025 scopus 로고
    • Role of oxidative stress in single-dose, cadmium-induced testicular cancer
    • Koizumi T., and Li Z.G. Role of oxidative stress in single-dose, cadmium-induced testicular cancer. J. Toxicol. Environ. Health 37 (1992) 25-36
    • (1992) J. Toxicol. Environ. Health , vol.37 , pp. 25-36
    • Koizumi, T.1    Li, Z.G.2
  • 16
    • 0017254074 scopus 로고
    • Regulation of ion permeabilities of isolated rat liver cells by external calcium concentration and temperature
    • Kolb H.A., and Adam G. Regulation of ion permeabilities of isolated rat liver cells by external calcium concentration and temperature. J. Membr. Biol. 84 (1976) 121-151
    • (1976) J. Membr. Biol. , vol.84 , pp. 121-151
    • Kolb, H.A.1    Adam, G.2
  • 17
    • 0027989808 scopus 로고
    • Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis
    • Koopman G., Reutelingsperger C.P., Kuijten G.A., Keehnen R.D., Pals S.T., and van Oers M.H. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 84 (1994) 1415-1420
    • (1994) Blood , vol.84 , pp. 1415-1420
    • Koopman, G.1    Reutelingsperger, C.P.2    Kuijten, G.A.3    Keehnen, R.D.4    Pals, S.T.5    van Oers, M.H.6
  • 18
    • 0029908940 scopus 로고    scopus 로고
    • Oxidative stress-mediated neurotoxicity of cadmium
    • Kumar R., Agarwal A.K., and Seth P.K. Oxidative stress-mediated neurotoxicity of cadmium. Toxicol. Lett. 89 (1996) 65-69
    • (1996) Toxicol. Lett. , vol.89 , pp. 65-69
    • Kumar, R.1    Agarwal, A.K.2    Seth, P.K.3
  • 19
    • 0027164227 scopus 로고
    • 2 formation and oxidative stress in vivo and in vitro in rat kidney mitochondria
    • 2 formation and oxidative stress in vivo and in vitro in rat kidney mitochondria. Biochem. Pharmacol. 45 (1993) 2017-2024
    • (1993) Biochem. Pharmacol. , vol.45 , pp. 2017-2024
    • Lund, B.O.1    Miller, D.M.2    Woods, J.S.3
  • 20
    • 0026050850 scopus 로고
    • Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps
    • Lytton J., Westlin M., and Hanley M.R. Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps. J. Biol. Chem. 266 (1991) 17067-17071
    • (1991) J. Biol. Chem. , vol.266 , pp. 17067-17071
    • Lytton, J.1    Westlin, M.2    Hanley, M.R.3
  • 21
    • 0032729493 scopus 로고    scopus 로고
    • Flow cytometric analysis on tri-n-butyltin-induced increase in annexin V binding to membranes of rat thymocytes
    • Nakata M., Oyama Y., Chikahisa L., Yamazaki Y., and Satoh M. Flow cytometric analysis on tri-n-butyltin-induced increase in annexin V binding to membranes of rat thymocytes. Environ. Toxicol. Pharmacol. 7 (1999) 267-273
    • (1999) Environ. Toxicol. Pharmacol. , vol.7 , pp. 267-273
    • Nakata, M.1    Oyama, Y.2    Chikahisa, L.3    Yamazaki, Y.4    Satoh, M.5
  • 24
    • 21344436393 scopus 로고    scopus 로고
    • Extracellular calcium is required for the maintenance of plasma membrane integrity in nucleated cells
    • Orlov S.N., Aksentsev S.L., and Kotelevtsev S.V. Extracellular calcium is required for the maintenance of plasma membrane integrity in nucleated cells. Cell Calcium 38 (2005) 53-57
    • (2005) Cell Calcium , vol.38 , pp. 53-57
    • Orlov, S.N.1    Aksentsev, S.L.2    Kotelevtsev, S.V.3
  • 28
    • 0032802394 scopus 로고    scopus 로고
    • Exposure of rat thymocytes to hydrogen peroxide increases annexin V binding to membranes: inhibitory action of deferoxamine and quercetin
    • Oyama Y., Noguchi S., Nakata M., Okada Y., Yamazaki Y., Funai M., Chikahisa L., and Kanemaru K. Exposure of rat thymocytes to hydrogen peroxide increases annexin V binding to membranes: inhibitory action of deferoxamine and quercetin. Eur. J. Pharmacol. 384 (1999) 47-52
    • (1999) Eur. J. Pharmacol. , vol.384 , pp. 47-52
    • Oyama, Y.1    Noguchi, S.2    Nakata, M.3    Okada, Y.4    Yamazaki, Y.5    Funai, M.6    Chikahisa, L.7    Kanemaru, K.8
  • 30
    • 0030916620 scopus 로고    scopus 로고
    • The antifungal imidazole clotrimazole and its major in vivo metabolite are potent blockers of the calcium-activated potassium channel in murine erythroleukemia cells
    • Rettenhouse A.R., Vandorpe D.H., Brugnara C., and Alper S.L. The antifungal imidazole clotrimazole and its major in vivo metabolite are potent blockers of the calcium-activated potassium channel in murine erythroleukemia cells. J. Membr. Biol. 157 (1997) 177-191
    • (1997) J. Membr. Biol. , vol.157 , pp. 177-191
    • Rettenhouse, A.R.1    Vandorpe, D.H.2    Brugnara, C.3    Alper, S.L.4
  • 31
    • 5044241759 scopus 로고    scopus 로고
    • Lead-induced oxidative stress and hematological alterations and their response to combined administration of calcium disodium EDTA with a thiol chelator in rats
    • Saxena G., and Flora S.J. Lead-induced oxidative stress and hematological alterations and their response to combined administration of calcium disodium EDTA with a thiol chelator in rats. J. Biochem. Mol. Toxicol. 18 (2004) 221-233
    • (2004) J. Biochem. Mol. Toxicol. , vol.18 , pp. 221-233
    • Saxena, G.1    Flora, S.J.2
  • 32
    • 0033012168 scopus 로고    scopus 로고
    • Oxidative stress as a mechanism of chronic cadmium-induced hepatotoxicity and renal toxicity and protection by antioxidants
    • Shaikh Z.A., Vu T.T., and Zaman K. Oxidative stress as a mechanism of chronic cadmium-induced hepatotoxicity and renal toxicity and protection by antioxidants. Toxicol. Appl. Pharmacol. 154 (1999) 256-263
    • (1999) Toxicol. Appl. Pharmacol. , vol.154 , pp. 256-263
    • Shaikh, Z.A.1    Vu, T.T.2    Zaman, K.3
  • 33
    • 14844312906 scopus 로고    scopus 로고
    • Intracerebral hemorrhage in the iron-deficient rat
    • Shao J., Xi G., Hua Y., Schallert T., and Felt B. Intracerebral hemorrhage in the iron-deficient rat. Stroke 36 (2005) 660-664
    • (2005) Stroke , vol.36 , pp. 660-664
    • Shao, J.1    Xi, G.2    Hua, Y.3    Schallert, T.4    Felt, B.5
  • 34
    • 0035865563 scopus 로고    scopus 로고
    • Critical role of calcium overloading in cadmium-induced apoptosis in mouse thymocytes
    • Shen H.M., Dong S.Y., and Ong C.N. Critical role of calcium overloading in cadmium-induced apoptosis in mouse thymocytes. Toxicol. Appl. Pharmacol. 171 (2001) 12-19
    • (2001) Toxicol. Appl. Pharmacol. , vol.171 , pp. 12-19
    • Shen, H.M.1    Dong, S.Y.2    Ong, C.N.3
  • 35
    • 0032561346 scopus 로고    scopus 로고
    • Clotrimazole, an antimycotic drug, inhibits the sarcoplasmic reticulum calcium pump and contractile function in heart muscle
    • Snajdrova L., Xu A., and Narayanan N. Clotrimazole, an antimycotic drug, inhibits the sarcoplasmic reticulum calcium pump and contractile function in heart muscle. J. Biol. Chem. 273 (1998) 28032-28039
    • (1998) J. Biol. Chem. , vol.273 , pp. 28032-28039
    • Snajdrova, L.1    Xu, A.2    Narayanan, N.3
  • 37
    • 0015837732 scopus 로고
    • The ionic permeability of the amphibian oocyte in the presence or absence of external calcium
    • Tupper J.T., and Maloff B.L. The ionic permeability of the amphibian oocyte in the presence or absence of external calcium. J. Exp. Zool. 185 (1973) 133-144
    • (1973) J. Exp. Zool. , vol.185 , pp. 133-144
    • Tupper, J.T.1    Maloff, B.L.2
  • 38
  • 39
    • 11844295378 scopus 로고    scopus 로고
    • Flow-cytometric analysis on cytotoxic effect of thimerosal, a preservative in vaccines, on lymphocytes dissociated from rat thymic glands
    • Ueha-Ishibashi T., Oyama Y., Nakao H., Umebayashi C., Hirama S., Sakai Y., Ishida S., and Okano Y. Flow-cytometric analysis on cytotoxic effect of thimerosal, a preservative in vaccines, on lymphocytes dissociated from rat thymic glands. Toxicol. In Vitro 19 (2005) 191-198
    • (2005) Toxicol. In Vitro , vol.19 , pp. 191-198
    • Ueha-Ishibashi, T.1    Oyama, Y.2    Nakao, H.3    Umebayashi, C.4    Hirama, S.5    Sakai, Y.6    Ishida, S.7    Okano, Y.8
  • 41
    • 85052609073 scopus 로고    scopus 로고
    • Deferoxamine reduces CFS free iron levels following intracerebral hemorrhage
    • Wan S., Hua Y., Keep R.F., Hoff J.T., and Xi G. Deferoxamine reduces CFS free iron levels following intracerebral hemorrhage. Acta Neurochir. Suppl. 96 (2006) 199-202
    • (2006) Acta Neurochir. Suppl. , vol.96 , pp. 199-202
    • Wan, S.1    Hua, Y.2    Keep, R.F.3    Hoff, J.T.4    Xi, G.5
  • 42
    • 33745685570 scopus 로고    scopus 로고
    • Oxidative stress in mouse brain exposed to lead
    • Wang J., Wu J., and Zhang Z. Oxidative stress in mouse brain exposed to lead. Ann. Occup. Hyg. 50 (2006) 405-409
    • (2006) Ann. Occup. Hyg. , vol.50 , pp. 405-409
    • Wang, J.1    Wu, J.2    Zhang, Z.3
  • 43
    • 0030682471 scopus 로고    scopus 로고
    • Imidazole antimycotics affect the activity of various ion channels and insulin secretion in mouse pancreatic B-cells
    • Welker S., and Drews G. Imidazole antimycotics affect the activity of various ion channels and insulin secretion in mouse pancreatic B-cells. Naunyn Schmiedebergs Arch. Pharmacol. 356 (1997) 543-550
    • (1997) Naunyn Schmiedebergs Arch. Pharmacol. , vol.356 , pp. 543-550
    • Welker, S.1    Drews, G.2
  • 44
    • 33750712565 scopus 로고    scopus 로고
    • Wolf, M.B., Baynes, J.W., 2006. Cadmium and mercury cause an oxidative stress-induced endothelial dysfunction. Biometals (Epub ahead of print).
  • 47
    • 0030068017 scopus 로고    scopus 로고
    • In vivo studies of cadmium-induced apoptosis in testicular tissue of the rat and its modulation by a chelating agent
    • Xu C., Johnson J.E., Singh P.K., Jones M.M., Yan H., and Carter C.E. In vivo studies of cadmium-induced apoptosis in testicular tissue of the rat and its modulation by a chelating agent. Toxicology 107 (1996) 1-8
    • (1996) Toxicology , vol.107 , pp. 1-8
    • Xu, C.1    Johnson, J.E.2    Singh, P.K.3    Jones, M.M.4    Yan, H.5    Carter, C.E.6
  • 48
    • 0035895838 scopus 로고    scopus 로고
    • 2+ on mesencephalic trigeminal neurons of the adult rat
    • 2+ on mesencephalic trigeminal neurons of the adult rat. Brain Res. 892 (2001) 102-110
    • (2001) Brain Res. , vol.892 , pp. 102-110
    • Yoshida, S.1
  • 49
    • 0023134858 scopus 로고
    • Interaction of azole antifungal agents with cytochrome P-45014DM purified from Saccharomyces cerevisiae microsomes
    • Yoshida Y., and Aoyama Y. Interaction of azole antifungal agents with cytochrome P-45014DM purified from Saccharomyces cerevisiae microsomes. Biochem. Pharmacol. 36 (1987) 229-235
    • (1987) Biochem. Pharmacol. , vol.36 , pp. 229-235
    • Yoshida, Y.1    Aoyama, Y.2


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