Property of thimerosal-induced decrease in cellular content of glutathione in rat thymocytes: A flow cytometric study with 5-chloromethylfluorescein diacetate

Toxicology in Vitro

Volumn 18, Issue 5, 2004, Pages 563-569

  Ueha Ishibashi, T ^a,b   Tatsuishi, T ^a   Iwase, K ^a   Nakao, H ^a   Umebayashi, C ^a   Nishizaki, Y ^a   Nishimura, Y ^a   Oyama, Y ^a   Hirama, S ^c   Okano, Y ^c  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b KUMAMOTO UNIVERSITY HOSPITAL   (Japan)

^c TOKUSHIMA BUNRI UNIVERSITY   (Japan)

Author keywords

Glutathione; Lymphocyte; Oxidative stress; Thimerosal

Indexed keywords

5 CHLOROMETHYLFLUORESCEIN DIACETATE; ACETIC ACID DERIVATIVE; CYSTEINE; GLUTATHIONE; THIOMERSAL; UNCLASSIFIED DRUG; VACCINE;

ARTICLE; ATTENUATION; BLOOD; CALCIUM CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; FLOW CYTOMETRY; IMMUNIZATION; INCUBATION TIME; NONHUMAN; OXIDATIVE STRESS; RAT; REDUCTION; THYMOCYTE;

ANIMALS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; FLOW CYTOMETRY; FLUORESCEINS; FLUORESCENT DYES; GLUTATHIONE; HYDROGEN PEROXIDE; LYMPHOCYTES; OXIDATIVE STRESS; PRESERVATIVES, PHARMACEUTICAL; RATS; RATS, WISTAR; THIMEROSAL; THYMUS GLAND;

EID: 3142600663     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2004.01.002     Document Type: Article

References (30)

1. Arata T., Oyama Y., Tabaru K., Satoh M., Hyashi H., Ishida S., Okano Y. Cytotoxic effects of triphenylbismuth on rat thymocytes: comparisons with bismuth chloride and triphenyltin chloride. Environmental Toxicology. 17:2002;472-477
2. Ball L.K., Ball R., Pratt R.D. An assessment of thimerosal use in childhood vaccines. Pediatrics. 107:2001;1147-1154
3. 2+ spike in HeLa cells by sensitizing the inositol 1, 4, 5-triphosphate receptor. Journal of Biological Chemistry. 267:1992;25113-25119
4. Buttke T.M., Sandstrom P.A. Redox regulation of programmed cell death Lymphocytes. Free Radical Research. 22:1995;389-397
5. Ca2+ channel of intermediate conductance in bovine aortic endothelial cells. Journal of Membrane Biology. 158:1997;147-158
6. 2+. Pharmacology and Toxicology. 71:1992;190-195
7. 2-induced changes in cell viability and cellular nonprotein thiol level of dissociated rat thymocytes. Japanese Journal of Pharmacology. 71:1996;299-305
8. Choi Y.B., Lipton S.A. Redox modulation of the NMDA receptor. Cellular and Molecular Life Science. 57:2000;1535-1541
9. Elliott S.J., Koliwad S.K. Redox control of ion channel activity in vascular endothelial cells by glutathione. Microcirculation. 4:1997;341-347
10. 2+ and membrane potential of thymocytes. Biochemica et Biophysica Acta. 1111:1992;65-74
11. Hampton M.B., Orrenius S. Redox regulation of apoptotic cell death in the immune system. Toxicology Letters. 102-103:1998;355-358
12. Kao J.P.Y., Harootunian A.T., Tsien P.Y. Photochemically generated cytosolic calcium pulses and their detection by fluo-3. Journal of Biological Chemistry. 264:1989;8179-8184
13. Ca) channels in myocytes of the guinea-pig taenia caeci. Journal of Physiology. 525:2000;363-376
14. Lipton S.A., Rayudu P.V., Choi Y.B., Sucher N.J., Chen H.S. Redox modulation of the NMDA receptor by NO-related species. Progress in Brain Research. 118:1998;73-82
15. Magos L. Neurotoxic character of thimerosal and the allometric extrapolation of adult clearance half-time to infants. Journal of Applied Toxicology. 23:2003;263-269
16. Magos L., Brown A.W., Sparrow S., Bailey E., Snowden R.T., Skipp W.R. The comparative toxicology of ethyl- and methylmercury. Archives of Toxicology. 57:1985;260-267
17. Marengo J.J., Hidalgo C., Bull R. Sulfhydryl oxidation modifies the calcium dependence of ryanodine-sensitive calcium channels of excitable cells. Biophysical Journal. 73:1998;1263-1277
18. Mates J.M., Perez-Gomez C., Nunez de Castro I., Asenjo M., Marquez J. Glutamine and its relationship with intracellular redox status, oxidative stress and cell proliferation/death. International Journal of Biochemistry and Cell Biology. 31:2002;697-703
19. Minta A., Kao J.P.Y., Tsien R.Y. Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores. Journal of Biological Chemistry. 264:1989;8171-8178
20. Nakao H., Umebayshi C., Nakata M., Nishizaki Y., Noda K., Okano Y., Oyama Y. Formaldehyde-induced shrinkage of rat thymocytes. Journal of Pharmacological Science. 91:2003;83-86
21. Pelassy C., Breittmayer J.P., Ticchioni M., Aussel C. Effect of thimerosal on cytosolic calcium and phosphatidylserine synthesis in Jurkat T cells. International Journal of Biochemistry. 26:1994;93-96
22. Pessah I.N. Ryanodine receptor acts as a sensor for redox stress. Pest Management Science. 57:2001;941-945
23. Pintado E., Baquero-Leonis D., Conde M., Sorbrino F. Effect of thimerosal and other sulfhydryl reagents on calcium permeability in thymus lymphocytes. Biochemical Pharmacology. 49:1995;227-232
24. Powis G., Briehl M., Oblong J. Redox signaling and the control of cell growth and death. Pharmacology and Therapeutics. 68:1995;149-173
25. Tanaka H., Makino Y., Okamoto K., Iida T., Yanm K., Yoshikawa N. Redox regulation of the glucocorticoid receptor. Antioxidants and Redox Signaling. 1:1999;403-423
26. Umebayashi C., Oyama Y., Chikahisa-Muramatsu L., Nakao N., Nishizaki Y., Nakata M., Soeda F., Takahama K. Tri-n-butyltin-induced cytotoxicity on rat thymocytes in presence and absence of serum. Toxicology In Vitro. 18:2004;55-61
27. Westphal G.A., Hallier E. Mercury in infants given vaccines containing thimerosal. Lancet. 360:2002;1731-1741
28. Westphal G.A., Asgari S., Schulz T.G., Bunger J., Muller M., Hallier E. Thimerosal induces micronuclei in the cytochalasin B-block micronucleus test with human lymphocytes. Archives of Toxicology. 77:2003;50-55
29. van't Veen A.J. Vaccines without thimerosal: why so necessary, why so long coming? Drugs. 61:2001;565-572
30. Yasutake A., Hirayama K., Inoue M. Mechanism of urinary excretion of methylmercury in mice. Archives of Toxicology. 63:1989;479-483