Developmental windows and environment as important factors in the expression of genetic information: A cardiovascular physiologist's view

Clinical Science

Volumn 111, Issue 5, 2006, Pages 295-305

  Kuneš, Jaroslav ^a   Zicha, Josef ^a  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

Author keywords

Cardiovascular phenotype development; Developmental window; Genetic determinant; Key environmental stimulus; Ontogenesis

Indexed keywords

BLOOD PRESSURE REGULATION; CARDIOVASCULAR DISEASE; DISEASE COURSE; ENVIRONMENTAL FACTOR; EPIGENETICS; ESSENTIAL HYPERTENSION; GENE EXPRESSION; GENE INTERACTION; GENETIC CODE; HEREDITARY HYPERTENSION; HOMEOSTASIS; HUMAN; MEDICAL SPECIALIST; ONTOGENY; PATHOGENESIS; PRIORITY JOURNAL; REVIEW;

AGE FACTORS; ANIMALS; CARDIOVASCULAR DISEASES; ENVIRONMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; HYPERTENSION; RISK FACTORS;

EID: 33750606519     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20050271     Document Type: Review

References (106)

1. McMillen, J. C. and Robinson, J. S. (2005) Developmental origins of the metabolic syndrome: prediction, plasticity, and programming. Physiol. Rev. 85, 571-633
2. Ošt'ádal, B., Ošt'ádalová, I. and Dhalla, N. S. (1999) Development of cardiac sensitivity to oxygen deficiency: comparative and ontogenetic aspects. Physiol. Rev. 79, 635-659
3. Wang, E. (1997) Regulation of apoptosis resistance and ontogeny of age-dependent diseases. Exp. Gerontol. 32, 471-484
4. Zicha, J. and Kuneš, J. (1999) Ontogenetic aspects of hypertension development: analysis in the rat. Physiol. Rev. 79, 1227-1282
5. Baldwin, H. S. (1996) Early embryonic vascular development. Cardiovasc. Res. 31, E34-E45
6. Segar, J. L. (1997) Ontogeny of the arterial and cardiopulmonary baroreflex during fetal and postnatal life. Am. J. Physiol. 273, R457-R471
7. Timberlake, D. S., O'Connor, D. T. and Parmer, R. J. (2001) Molecular genetics of essential hypertension: recent results and emerging strategies. Curr. Opin. Nephrol. Hypertens. 10, 71-79
8. Křeček, J. (1971) The theory of critical developmental periods and postnatal development of endocrine functions. In The Biopsychology of Development (Tobach, E., Aronson, L. R. and Shaw, E., eds.), pp. 233-248, Academic Press, New York
9. Albrecht, I. (1974) Critical period for the development of spontaneous hypertension in rats. Mech. Ageing Dev. 3, 75-79
10. Jelínek, J. (1970) Prepuberty as a critical period for experimental hypertension in the rat. In The Postnatal Development of Phenotype (Denenberg, V. J. and Kazda, S., eds.), pp. 33-44, Butterworth, London
11. Harrap, S. B., Van Der Merwe, W. M., Griffin, S. A., MacPherson, F. and Lever, A. F. (1990) Brief angiotensin converting enzyme inhibitor treatment in young spontaneously hypertensive rats reduces blood pressure long-term. Hypertension 16, 603-614
12. Grisk, O. and Rettig, R. (2004) Interactions between the sympathetic nervous system and the kidneys in arterial hypertension. Cardiovasc. Res. 61, 238-246
13. Hoet, J. J. and Hanson, M. A. (1999) Intrauterine nutrition: its importance during critical periods for cardiovascular and endocrine development. J. Physiol. 514, 617-627
14. Langley-Evans, S. C. (2001) Fetal programming of cardiovascular function through exposure to maternal undernutrition. Proc. Nutr. Soc. 60, 505-513
15. Khalil, R. A. and Granger, J. P. (2002) Vascular mechanisms of increased arterial pressure in preeclampsia: lessons from animal models. Am. J. Physiol. Renal Physiol. 283, R29-R45
16. Seckl, J. R. (2001) Glucocorticoid programming of the fetus; adult phenotypes and molecular mechanisms. Mol. Cell. Endocrinol. 185, 61-71
17. Ozanne, S. E. (2001) Metabolic programming in animals. Br. Med. Bull. 60, 143-152
18. Gorski, R. A. (1966) Localisation and sexual differentiation of the nervous structures which regulate ovulation, J. Reprod. Fertil. (Suppl. I), 67-88
19. Harris, G. W. (1964) Sex hormones, brain development and brain function. Endocrinology 75, 627-648
20. Křeček, J. (1973) Sex differences in salt taste: the effect of testosterone. Physiol. Behav. 10, 683-688
21. Cambotti, L. J., Cole, F. E., Gerall, A. A., Frohlich, E. D. and MacPhee, A. A. (1984) Neonatal gonadal hormones and blood pressure in the spontaneously hypertensive rat. Am. J. Physiol. 247, E258-E264
22. Ganten, U., Schröder, G., Witt, M. et al. (1989) Sexual dimorphism of blood pressure in spontaneously hypertensive rats: effects of anti-androgen treatment. J. Hypertens. 7, 721-726
23. Hampl, V, Bíbová, J., Ošt'ádalová, I., Povýšilová, V. and Herget, J. (2003) Gender differences in the long-term effects of perinatal hypoxia on pulmonary circulation in rats. Am. J. Physiol. Lung Cell Mol. Physiol. 285, L386-L392
24. Bačáková, L. and Kuneš, J. (1995) Sex-dependent differences in growth of vascular smooth muscles cells from spontaneously hypertensive rats. Physiol. Res. 44, 127-130
25. Bačáková, L. and Kuneš, J. (2000) Gender differences in growth of vascular smooth muscle cells isolated from hypertensive and normotensive rats. Clin. Exp. Hypertens. 22, 33-44
26. Bačáková, L., Mareš, V., Lisá, V. and Kocourek, F. (1997) Sex-dependent differences in growth and morphology of cultured vascular smooth muscle cells from newborn rats. Physiol. Res. 46, 403-406
27. McCarty, R., Cierpial, M. A., Murphy, C. A., Lee, J. H. and Fields-Okotcha, C. (1992) Maternal involvement in the development of cardiovascular phenotype. Experientia 48, 315-322
28. Myers, M. M. (1996) Enduring effects of infant feeding experiences on adult blood pressure. Psychosom. Med. 58, 612-621
29. Šedová, L., Berube, J., Tremblay, J. et al. (2003) The epigenetic effect of maternal age during pregnancy on offspring's blood pressure in adulthood is regulated by genes on rat chromosome 20. Hypertension 22, 445
30. Babický, A., Ošt'ádalová, I., Pařízek, J., Kolář, J. and Bíbr, B. (1973) Onset and duration of the physiological weaning period for infant rats reared in nests of different sizes. Physiol. Bohemoslov. 22, 449-456
31. Babický, A., Pařízek, J., Ošt'á dalová, I. and Kolář, J. (1973b) Initial solid food intake and growth of young rats in nests of different sizes. Physiol. Bohemoslov. 22, 557-566
32. Smith, P. G., Poston, C. W. and Nills, E. (1984) Ontogeny of neural and non-neural contributions to arterial blood pressure in spontaneously hypertensive rats. Hypertension 6, 54-60
33. Tucker, D. C. and Johnson, A. K. (1984) Development of autonomic control of heart rate in genetically hypertensive and normotensive rats. Am. J. Physiol. 246, R570-R577
34. McCarty, R., Tong, H. and Forsythe, R. C. (1992) Electrolyte content of milk differs in normotensive and spontaneously hypertensive rats. Psychobiology 20, 307-310
35. Mills, D. E., Ward, R. P. and Huang, Y. S. (1990) Fatty acid composition of milk from genetically normotensive and hypertensive rats. J. Nutr. 120, 431-435
36. Gouldsborough, I., Black, V., Johnson, I. T. and Ashton, N. (1998) Maternal nursing behaviour and the delivery of milk to the neonatal spontaneously hypertensive rat. Acta Physiol. Scand. 162, 107-114
37. Rose, J. L. and McCarty, R. (1994) Maternal influences on milk intake in SHR and WKY pups. Physiol. Behav. 56, 901-906
38. McCarron, D. A., Yung, N. N., Ugoretz, B. A. and Krutzik, S. (1981) Disturbances of calcium metabolism in the spontaneously hypertensive rat. Hypertension 3 (Suppl. I), I162-I167
39. Hatton, D. C., Muntzel, M., McCarron, D. A., Presley, M. and Bukoski, R. D. (1988) Early effects of dietary calcium on blood pressure, plasma volume, and vascular reactivity. Kidney Int. 34 (Suppl. 25), S16-S18
40. Peuler, J. D., Morgan, D. A. and Mark, A. L. (1987) High calcium diet reduces blood pressure in Dahl salt-sensitive rats by neural mechanisms. Hypertension 9 (Suppl. III), III159-III165
41. Kuneš, J., Zicha, J. and Hamet, P. (1988) Effects of dietary calcium on the development of salt hypertension in young and adult Dahl rats. J. Hypertens. 6 (Suppl. 4), S225-S227
42. Peuler, J. D. and Mark, A. L. (1989) Aggravation of salt-induced hypertension in Dahl rats by 2% supplemental dietary calcium. Hypertension 13, 929-934
43. Workman, M. L. and Paller, M. S. (1985) Cardiovascular and endocrine effects of potassium in spontaneously hypertensive rats. Am. J. Physiol. 249, H907-H913
44. + treatment. Clin. Sci. 72, 321-327
45. Dahl, L. K., Leitl, G. and Heine, M. (1972) Influence of dietary potassium and sodium/potassium molar ratios on the development of salt hypertension. J. Exp. Med. 136, 318-330
46. Ganguli, M. and Tobian, L. (1991) In SHR rats, dietary potassium determines NaCl sensitivity in NaCl-induced rises of blood pressure. Clin. Exp. Hypertens. A 13, 677-685
47. Coates, P. M., Brown, S. A., Sonawane, B. R. and Koldovský, O. (1983) Effect of early nutrition on serum cholesterol levels in adult rats challenged with high fat diet. J. Nutr. 113, 1046-1050
48. Hahn, P., Girard, J., Assan, J., Kervran, A. and Koldovský, O. (1978) Late effects of premature weaning to different diets in the rat. J. Nutr. 108, 1783-1787
49. Hahn, P. and Srubiski, L. (1990) Development of cholesterol metabolism: the effect of diet composition at weaning. Biol. Neonate 58, 1-7
50. Hahn, P. (1982) Development of lipid metabolism. Annu. Rev. Nutr. 2, 91-111
51. Morton, J. J., Beattie, E. C. and MacPherson, F. (1992) Angiotensin II receptor antagonist losartan has persistent effects on blood pressure in the young spontaneously hypertensive rat: lack of relation to vascular structure. J. Vasc. Res. 29, 264-269
52. Nakaya, H., Sasamura, H., Mifune, M. et al. (2002) Prepubertal treatment with angiotensin receptor blocker causes partial attenuation of hypertension and renal damage in adult Dahl salt-sensitive rats. Nephron 91, 710-718
53. Berecek, K. H., Kirk, K. A., Nagahama, S. and Oparil, S. (1987) Sympathetic function in spontaneously hypertensive rats after chronic administration of captopril. Am. J. Physiol. 252, H796-H806
54. Kuneš, J., Dobešová, Z. and Zicha, J. (2005) Angiotensin-dependent sympathetic vasoconstriction in SHR: the effect of captopril treatment in young animals. J. Hypertens. 23 (Suppl. 2), S234
55. Egger, G., Liang, G., Aparicio, A. and Jones, P. A. (2004) Epigenetics in human disease and prospects for epigenetic therapy. Nature (London) 429, 457-463
56. Barker, D. J., Osmond, C., Golding, J., Kuh, D. and Wodsworth, M. E. (1989) Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease. Br. Med. J. 298, 564-567
57. Godfrey, K. M. and Barker, D. J. (2000) Fetal nutrition and adult disease. Am. J. Clin. Nutr. 71 (Suppl.), 1344S-1352S
58. Kafri, T., Ariel, M., Brandeis, M. et al. (1992) Developmental patterns of gene-specific DNA methylation in the mouse embryo and germline. Genes Dev. 6, 705-714
59. Bogdarina, I., Murphy, H. C., Burns, S. P. and Clark, A. J. L. (2004) Investigation of the role of epigenetic modification of the rat glucokinase gene in fetal programming. Life Sci. 74, 1407-1415
60. Lillycrop, K. A., Phillips, E. S., Jackson, A. A., Hanson, M. A. and Burdge, G. C. (2005) Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring. J. Nutr. 135, 1382-1386
61. Drake, A. J., Walker, B. R. and Seckl, J. R. (2005) Intergenerational consequences of fetal programming by in utero exposure to glucocorticoids in rats. Am. J. Physiol. Regulatory Integrative Comp. Physiol. 288, R34-R38
62. Alikhani-Koopaei, R., Fouladkou, F., Frey, F. J. and Frey, B. M. (2004) Epigenetic regulation of 11β-hydroxysteroid dehydrogenase type 2 expression. J. Clin. Invest. 114, 1146-1157
63. Ferrari, P., Sansonnens, A., Dick, B. and Frey, F. J. (2001) In vivo 11β-HSD-2 activity: variability salt-sensitivity, and effect of licorice. Hypertension 38, 1330-1336
64. Gibson, G. (1996) Epistasis and pleiotropy as natural properties of transcriptional regulation. Theor. Popul. Biol. 49, 58-89
65. Dominiczak, A., Graham, D., McBride, M. W. et al. (2005) Cardiovascular genomics and oxidative stress. Hypertension 45, 636-642
66. Doris, P. (2002) Hypertension genetics, single nucleotide polymorphisms, and the common disease: common variant hypothesis. Hypertension 39, 323-331
67. Glazier, A. M., Nadeu, J. H. and Aitman, T. J. (2002) Finding genes that underlie complex traits. Science 298, 2345-2349
68. Hübner, N., Yagil, C. and Yagil, Y. (2006) Novel integrative approaches to the identification of candidate genes in hypertension. Hypertension 47, 1-5
69. Rapp, J. P. (2000) Genetic analysis of inherited hypertension in the rat. Physiol. Rev. 8, 135-172
70. Svenson, K. L., Bogue, M. A. and Peters, L. L. (2003) Identifying new mouse models of cardiovascular disease: a review of high-throughput screens of mutagenized and inbred strains. J. Appl. Physiol. 94, 1650-1659
71. Rapp, J. P. (1983) A paradigm for identification of primary genetic causes of hypertension in rats. Hypertension 5 (Suppl. I), I198-I203
72. Jacob, J. H. (1999) Physiological genetics: application to hypertension research. Clin. Exp. Pharmacol. Physiol. 26, 530-535
73. Veerasingham, S. J., Sellers, K. W. and Raizada, M. K. (2004) Functional genomics as an emerging strategy for the investigation of central mechanisms in experimental hypertension. Prog. Biophys. Mol. Biol. 84, 107-123
74. Andersson, L. (2005) Candidate-based proteomics in the search for biomarkers of cardiovascular disease. J. Physiol. 563, 23-60
75. Gallego-Delgado, J., Lazaro, A., Osende, J. L. et al. (2005) Proteomic approach in the search of new cardiovascular biomarkers, Kidney Int. (Suppl. 99) S103-S107
76. Lam, L., Lind, J. and Semsarian, C. (2006) Application of proteomics in cardiovascular medicine. Int. J. Cardiol. 108, 12-19
77. Cowley, A. W. (2003) Genomics and homeostasis. Am. J. Physiol. Regulatory Integrative Com. Physiol. 284, R611-R627
78. Greenland, S. and Rothman, K. J. (1998) Concepts of interaction. In Modern Epidemiology (Rothman, K. J. and Greenland, S., eds.), pp. 329-342, Lippincott-Raven, Philadelphia
79. Ottman, R. (1996) Gene-environment interaction: definitions and study designs. Prev. Med. 25, 764-770
80. O'Keefe, Jr, J. H. and Cordain, L. (2004) Cardiovascular disease resulting from a diet and lifestyle at odds with our Paleolithic genome: how to become a 21st-century hunter-gatherer. Mayo Clin. Proc. 79, 101-108
81. Zicha, J., Kuneš, J. and Jelínek, J. (1986) Experimental hypertension in young and adult animals. Hypertension 8, 1096-1104
82. Ben-Ishay, D. and Yagil, Y. (1994) The Sabra hypertension-prone and -resistant strains. In Handbook of Hypertension, vol. 16: Experimental and Genetic Models of Hypertension (Ganten, D. and de Jong, W., eds.), pp. 272-299, Elsevier, Amsterdam
83. Dahl, L. K., Heine, M. and Tassinari, L. (1962) Effects of chronic excess salt ingestion. Evidence that genetic factors play an important role in susceptibility to experimental hypertension. J. Exp. Med. 115, 1173-1190
84. Rapp, J. P. (1982) Dahl salt-susceptible and salt-resistant rats. A review. Hypertension 4, 753-763
85. Křeček, J., Dlouhá, H. and Zicha, J. (1982) Salt supply in early life and possible consequences for hypertension in adult life. Bibl. Nutr. Dieta. 31, 121-130
86. Dene, H. and Rapp, J. P. (1985) Lack of effects of maternal salt intake on blood pressure of offspring in Dahl salt-sensitive rats. Clin. Exp. Hypertens. A 7, 1121-1133
87. Hazon, N., Parker, C., Leonard, R. and Henderson, I. W. (1988) Influence of an enriched dietary sodium chloride regime during gestation and suckling and post-natally on the ontogeny of hypertension in the rat. J. Hypertens. 6, 517-524
88. Dahl, L. K., Knudsen, K. D., Heine, M. A. and Leitl, G. J. (1968) Effects of chronic excess salt ingestion. Modification of experimental hypertension in the rat by variations in the diet. Circ. Res. 22, 11-18
89. + transport in red blood cells of Dahl rats. Effects of age and salt. Hypertension 15, 612-627
90. Racasan, S., Braam, B., Koomans, H. A. and Joles, J. A. (2005) Programming blood pressure in adult SHR by shifting perinatal balance of NO and reactive oxygen species toward NO: the inverted Barker phenomenon. Am. J. Physiol. Renal Physiol. 288, F626-F636
91. Mashimo, T., Nabika, T., Matsumoto, C., Tamada, T. et al. (1999) Aging and salt-loading modulate blood pressure QTLs in rats. Am. J. Hypertens. 12, 1098-1104
92. Samani, N. J., Gauguier, D., Vincent, M. et al. (1996) Analysis of quantitative trait loci for blood pressure on rat chromosomes 2 and 13. Age-related differences in effect. Hypertension 28, 1118-1122
93. Schork, N. J., Nath, S. P., Lindpaintner, K. and Jacob, H. J. (1996) Extensions to quantitative trait locus mapping in experimental organisms. Hypertension 28, 1104-1111
94. Iyer, S. N., Lu, D., Katovich, M. J. and Raizada, M. K. (1996) Chronic control of high blood pressure in the spontaneously hypertensive rat by delivery of angiotensin type 1 receptor antisense. Proc. Natl. Acad. Sci. U.S.A. 93, 9960-9965
95. Martens, J. R., Reaves, P. Y., Lu, D. et al. (1998) Prevention of renovascular and cardiac pathophysiological changes in hypertension by angiotensin II type 1 receptor antisense gene therapy. Proc. Natl. Acad. Sci. U.S.A. 95, 2664-2669
96. Katovich, M. J., Gelband, C. H., Reaves, P., Wang, H. W. and Raizada, M. K. (1999) Reversal of hypertension by angiotensin II type 1 receptor antisense gene therapy in the adult SHR. Am. J. Physiol. 277, H1260-H1264
97. Adams, M. A., Bobik, A. and Korner, P. I. (1990) Enalapril can prevent vascular amplifier development in spontaneously hypertensive rats. Hypertension 16, 252-260
98. Kost, Jr, C. K., Li, P. and Jackson, E. K. (1995) Blood pressure after captopril withdrawal from spontaneously hypertensive rats. Hypertension 25, 82-87
99. Smallegange, C., Hale, T. M., Bushfield, T. L. and Adams, M. A. (2004) Persistent lowering of pressure by transplanting kidneys from adult spontaneously hypertensive rats treated with brief antihypertensive therapy. Hypertension 44, 89-94
100. Leenen, F. H., Ruzicka, M. and Huang, B. S. (2002) The brain and salt-sensitive hypertension. Curr. Hypertens. Rep. 4, 129-135
101. Zicha, J., Dobešová, Z., Hojná, S. and Kuneš, J. (2005) Transient captopril treatment of SHR in juvenile developmental window: mechanism of persistent BP reduction. Hypertension 46, 912
102. Huang, B. S. and Leenen, F. H. (1998) Both brain angiotensin II and 'ouabain' contribute to sympathoexcitation and hypertension in Dahl S rats on high salt intake. Hypertension 32, 1028-1033
103. Zhao, X., White, R., Huang, B. S., Van Huysse, J. and Leenen, F. H. (2001) High salt intake and the brain renin-angiotensin system in Dahl salt-sensitive rats. J. Hypertens. 19, 89-98
104. Zicha, J., Dobešová, Z. and Kuneš, J. (2001) Relative deficiency of nitric oxide-dependent vasodilation in salt hypertensive Dahl rats: the possible role of superoxide anions. J. Hypertens. 19, 247-254
105. Wu, G., Bazer, F. W., Cudd, T. A., Meininger, C. J. and Spencer, T. E. (2004) Maternal nutrition and fetal development. J. Nutr. 134, 2169-2172
106. Pravenec, M., Klír, P., Křen, V., Zicha, J. and Kuneš, J. (1989) An analysis of spontaneous hypertension in spontaneously hypertensive rats by means of new recombinant inbred strains. J. Hypertens. 7, 217-221