Physiological genetics: Application to hypertension research

Clinical and Experimental Pharmacology and Physiology

Volumn 26, Issue 7, 1999, Pages 530-535

  Jacob, Howard J ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Animal models; Genetics; Hypertension; Physiology

Indexed keywords

ANIMAL MODEL; CLINICAL RESEARCH; CONFERENCE PAPER; EXPRESSED SEQUENCE TAG; GENE EXPRESSION; GENE ISOLATION; GENE LOCUS; GENE MAPPING; GENETIC SUSCEPTIBILITY; GENOME; HYPERTENSION; MOLECULAR CLONING; MOLECULAR GENETICS; MULTIFACTORIAL INHERITANCE; NONHUMAN; PHENOTYPE; QUANTITATIVE TRAIT; RAT; STRAIN DIFFERENCE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; DISEASE MODELS, ANIMAL; GENOME; HUMANS; HYPERTENSION; PHENOTYPE; RATS; RESEARCH DESIGN;

EID: 0033029588     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.1999.03078.x     Document Type: Conference Paper

References (18)

1. 1. Yamori Y. Physiopathology of the various strains of spontaneously hypertensive rats. In: Genest J, Kuchel O, Hamet P, Cantin M (eds). Hypertension, 2nd edn. 1983; 556-81.
2. 2. Lander ES, Schork NJ. Genetic dissection of complex diseases. Science 1994; 265: 2037-48.
3. 3. Krugliak L, Lander ES. Complex multipoint sib-pair analysis of qualitative and quantitative traits. Am. J. Hum. Genet. 1995; 57: 439-54.
4. 4. Elston RC. Algorithms and inferences: The challenge of multifactorial diseases. Am. J. Hum. Genet. 1997; 60: 255-62.
5. 5. Schork NJ, Nath SP, Lindpaintner KL et al. Extensions to QTL mapping in experimental organisms. Hypertension 1996; 28: 1104-11.
6. 6. Lindpaintner K, Hilbert P, Ganten D et al. Molecular genetics of the SA-gene: Cosegregation with hypertension and mapping to rat chromosome 1. J. Hypertens. 1993; 11: 19-23.
7. 7. Samani N, Lodwick D, Vincent M et al. A gene differentially expressed in the kidney of the spontaneously hypertensive rat cosegregates with increased blood pressure. J. Clin. Invest 1993; 92: 1099-2005.
8. 8. Harris EL, Dene H, Rapp JP. SA gene and blood pressure cosegregates using Dahl salt-sensitive rats. Am. J. Hypertens. 1993; 6: 330-4.
9. A gene locus as a candidate locus for essential hypertension. Hypertension 1994; 23: 375-80.
10. A locus in human hypertension. Hypertension 1995; 25: 6-13.
11. 11. Jiang J, Stec D, Drummond H et al. Transfer of a salt-resistant renin allele raises blood pressure in Dahl salt-sensitive rats. Hypertension 1997; 29: 619-27.
12. 12. Lande R, Thompson R. Efficiency of marker-assisted selection in the improvement of quantitative traits. Genetics 1990; 124: 743-56.
13. 13. Rapp JP, Wang S, Dene H. Effect of genetic background on cosegregation of renin alleles and blood pressure in Dahl rats. Am. J. Hypertens. 1990; 3: 391-6.
14. 14. Haldi ML, Lim P, Kaphingst K, Akella U, Whang J, Lander ES. Construction of a large-insert yeast artificial chromosome library of the rat genome. Mammalian Genome 1997; 8: 460.
15. 15. Cai L, Schalkwyk LC, Schoeberlein-Stehli A et al. Construction and characterisation of a 10-genome equivalent yeast artificial chromosome library for the laboratory rat, Rattus norvegicus. Genomics 1997; 39: 385-92.
16. 16. DeRisi J, Penland L, Brown PO et al. Use of a cDNA microarray to analyze gene expression patterns in human cancer. Nature Genet. 1996; 14: 457-60.
17. 17. Julier C, Delepine M, Keavney B et al. Genetic susceptibility for human familial essential hypertension in a region of homology with blood pressure linkage on rat chromosome 10. Human Mol. Genet. 1997; 6: 2077-85.
18. 18. Mansfield TA, Simon DB, Farfel Z et al. Multilocus linkage of familial hyperkalaemia and hypertension, pseudohypoaldosteronism type II, to chromosomes 1q31-42 and 17p11-q21. Nature Genet. 1997; 16: 202-5.