메뉴 건너뛰기




Volumn 17, Issue 5, 2006, Pages 769-778

Genomic abnormalities in chronic lymphocytic leukemia influence gene expression by a gene dosage effect

Author keywords

Chronic lymphocytic leukemia; Genomic abnormalities

Indexed keywords

ADULT; AGED; ARTICLE; CHROMOSOME 11; CHROMOSOME 12; CHROMOSOME 13; CHROMOSOME ABERRATION; CHROMOSOME BANDING PATTERN; CHROMOSOME DELETION; CHRONIC LYMPHATIC LEUKEMIA; CLUSTER ANALYSIS; DNA MICROARRAY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DOSAGE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HUMAN; KARYOTYPING; MALE; MIDDLE AGED; PATHOLOGY; SURVIVAL; TRISOMY;

EID: 33750604336     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.17.5.769     Document Type: Article
Times cited : (12)

References (42)
  • 1
    • 4344715624 scopus 로고    scopus 로고
    • Perspectives in chronic lymphocytic leukemia biology and management
    • DOI 10.1016/j.hoc.2004.04.002, PII S088985880400036X
    • Dighiero G: Perspectives in chronic lymphocytic leukemia biology and management. Hematol Oncol Clin North Am 18: 927-943, 2004. (Pubitemid 39119833)
    • (2004) Hematology/Oncology Clinics of North America , vol.18 , Issue.4 , pp. 927-943
    • Dighiero, G.1
  • 3
    • 0032941221 scopus 로고    scopus 로고
    • B-cell chronic lymphocytic leukemia: A bird of a different feather
    • Caligaris-Cappio F and Hamblin TJ: B-cell chronic lymphocytic leukemia: a bird of a different feather. J Clin Oncol 17: 399-408, 1999. (Pubitemid 29022419)
    • (1999) Journal of Clinical Oncology , vol.17 , Issue.1 , pp. 399-408
    • Caligaris-Cappio, F.1    Hamblin, T.J.2
  • 4
    • 0031913662 scopus 로고    scopus 로고
    • Clinical utility of flow cytometry in the chronic lymphoid leukemias
    • Di Giuseppe JA and Borowitz MJ: Clinical utility of flow cytometry in the chronic lymphoid leukemias. Semin Oncol 25: 6-10, 1998.
    • (1998) Semin Oncol , vol.25 , pp. 6-10
    • Di Giuseppe, J.A.1    Borowitz, M.J.2
  • 5
    • 4344568293 scopus 로고    scopus 로고
    • Definition and diagnosis of sporadic and familial chronic lymphocytic leukemia
    • DOI 10.1016/j.hoc.2004.04.009, PII S0889858804000437
    • Catovsky D: Definition and diagnosis of sporadic and familial chronic lymphocytic leukemia. Hematol Oncol Clin North Am 18: 783-794, 2004. (Pubitemid 39119824)
    • (2004) Hematology/Oncology Clinics of North America , vol.18 , Issue.4 , pp. 783-794
    • Catovsky, D.1
  • 7
    • 0037541558 scopus 로고    scopus 로고
    • Chromosome anomalies detected by interphase fluorescence in situ hybridization: Correlation with significant biological features of B-cell chronic lymphocytic leukaemia
    • Dewald GW, Brockman SR, Paternoster SF, et al: Chromosome anomalies detected by interphase fluorescence in situ hybridization: correlation with significant biological features of B-cell chronic lymphocytic leukaemia. Br J Haematol 121: 287-295, 2003.
    • (2003) Br J Haematol , vol.121 , pp. 287-295
    • Dewald, G.W.1    Brockman, S.R.2    Paternoster, S.F.3
  • 8
    • 0033050007 scopus 로고    scopus 로고
    • Chromosome aberrations in B-cell chronic lymphocytic leukemia: Reassessment based on molecular cytogenetic analysis
    • Dohner H, Stilgenbauer S, Dohner K, et al: Chromosome aberrations in B-cell chronic lymphocytic leukemia: reassessment based on molecular cytogenetic analysis. J Mol Med 77: 266-281, 1999. (Pubitemid 29146578)
    • (1999) Journal of Molecular Medicine , vol.77 , Issue.2 , pp. 266-281
    • Dohner, H.1    Stilgenbauer, S.2    Dohner, K.3    Bentz, M.4    Lichter, P.5
  • 9
    • 0018946008 scopus 로고
    • Nonrandom chromosomal aberrations in chronic lymphocytic leukemia revealed by polyclonal B-cell-mitogen stimulation
    • Gahrton G, Robert KH, Friberg K, et al: Non-random chromosomal aberrations in chronic lymphocytic leukemia revealed by polyclonal B-cell-mitogen stimulation. Blood 56: 640-647, 1980. (Pubitemid 10005668)
    • (1980) Blood , vol.56 , Issue.4 , pp. 640-647
    • Gahrton, G.1    Robert, K.H.2    Friberg, K.3
  • 10
  • 11
    • 0034727833 scopus 로고    scopus 로고
    • Genomic aberrations and survival in chronic lymphocytic leukemia
    • Dohner H, Stilgenbauer S, Benner A, et al: Genomic aberrations and survival in chronic lymphocytic leukemia. N Engl J Med 343: 1910-1916, 2000.
    • (2000) N Engl J Med , vol.343 , pp. 1910-1916
    • Dohner, H.1    Stilgenbauer, S.2    Benner, A.3
  • 12
    • 14144254149 scopus 로고    scopus 로고
    • Unique gene expression and clinical characteristics are associated with the 11q23 deletion in chronic lymphocytic leukaemia
    • Dickinson JD, Smith LM, Sanger WG, et al: Unique gene expression and clinical characteristics are associated with the 11q23 deletion in chronic lymphocytic leukaemia. Br J Haematol 128: 460-471, 2005.
    • (2005) Br J Haematol , vol.128 , pp. 460-471
    • Dickinson, J.D.1    Smith, L.M.2    Sanger, W.G.3
  • 13
    • 3042814553 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization detection of cytogenetic abnormalities in B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma
    • Aoun P, Blair HE, Smith LM, et al: Fluorescence in situ hybridization detection of cytogenetic abnormalities in B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma. Leuk Lymphoma 45: 1595-1603, 2004.
    • (2004) Leuk Lymphoma , vol.45 , pp. 1595-1603
    • Aoun, P.1    Blair, H.E.2    Smith, L.M.3
  • 15
    • 0034807713 scopus 로고    scopus 로고
    • Analysing gene expression data from DNA microarrays to identify candidate genes
    • Wu TD: Analysing gene expression data from DNA microarrays to identify candidate genes. J Pathol 195: 53-65, 2001.
    • (2001) J Pathol , vol.195 , pp. 53-65
    • Wu, T.D.1
  • 16
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • Tusher VG, Tibshirani R and Chu G: Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 98: 5116-5121, 2001.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 17
    • 26444531971 scopus 로고    scopus 로고
    • Distinct gene expression profiles in different B-cell compartments in human peripheral lymphoid organs
    • Shen Y, Iqbal J, Xiao L, et al: Distinct gene expression profiles in different B-cell compartments in human peripheral lymphoid organs. BMC Immunol 5: 20, 2004.
    • (2004) BMC Immunol , vol.5 , pp. 20
    • Shen, Y.1    Iqbal, J.2    Xiao, L.3
  • 18
    • 0031840623 scopus 로고    scopus 로고
    • Quantitation of minimal residual disease in Philadelphia chromosome positive chronic myeloid leukaemia patients using real-time quantitative RT-PCR
    • Mensink E, van de Locht A, Schattenberg A, et al: Quantitation of minimal residual disease in Philadelphia chromosome positive chronic myeloid leukaemia patients using real-time quantitative RT-PCR. Br J Haematol 102: 768-774, 1998.
    • (1998) Br J Haematol , vol.102 , pp. 768-774
    • Mensink, E.1    Van De Locht, A.2    Schattenberg, A.3
  • 19
    • 30644456577 scopus 로고    scopus 로고
    • 11q22.3 deletion in B-CLL is specifically associated with bulky lymphadenopathy CD26, CCL17, and ZAP-70 expression but not reduced expression of adhesion/cell surface receptor molecules
    • Dickinson JDGJ, Iqbal J, Lynch JC, Chan J, Bierman PJ and Joshi SS: 11q22.3 deletion in B-CLL is specifically associated with bulky lymphadenopathy CD26, CCL17, and ZAP-70 expression but not reduced expression of adhesion/cell surface receptor molecules. Leuk Lymphoma 47: 231-244, 2006.
    • (2006) Leuk Lymphoma , vol.47 , pp. 231-244
    • Dickinson, J.D.G.J.1    Iqbal, J.2    Lynch, J.C.3    Chan, J.4    Bierman, P.J.5    Joshi, S.S.6
  • 20
    • 0029969111 scopus 로고    scopus 로고
    • Molecular cytogenetic delineation of a novel critical genomic region in chromosome bands 11q22.3-923.1 in lymphoproliferative disorders
    • Stilgenbauer S, Liebisch P, James MR, et al: Molecular cytogenetic delineation of a novel critical genomic region in chromosome bands 11q22.3-923.1 in lymphoproliferative disorders. Proc Natl Acad Sci USA 93: 11837-11841, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11837-11841
    • Stilgenbauer, S.1    Liebisch, P.2    James, M.R.3
  • 22
    • 5444276626 scopus 로고    scopus 로고
    • Microarray gene expression profiling of B-cell chronic lymphocytic leukemia subgroups defined by genomic aberrations and VH mutation status
    • Haslinger C, Schweifer N, Stilgenbauer S, et al: Microarray gene expression profiling of B-cell chronic lymphocytic leukemia subgroups defined by genomic aberrations and VH mutation status. J Clin Oncol 22: 3937-3949, 2004.
    • (2004) J Clin Oncol , vol.22 , pp. 3937-3949
    • Haslinger, C.1    Schweifer, N.2    Stilgenbauer, S.3
  • 23
    • 0024352654 scopus 로고
    • Molecular analyses of chromosome 12 in chronic lymphocytic leukemia
    • Einhorn S, Burvall K, Juliusson G, et al: Molecular analyses of chromosome 12 in chronic lymphocytic leukemia. Leukemia 3: 871-874, 1989.
    • (1989) Leukemia , vol.3 , pp. 871-874
    • Einhorn, S.1    Burvall, K.2    Juliusson, G.3
  • 24
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
    • Alizadeh AA, Eisen MB, Davis RE, et al: Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403: 503-511, 2000.
    • (2000) Nature , vol.403 , pp. 503-511
    • Alizadeh, A.A.1    Eisen, M.B.2    Davis, R.E.3
  • 25
    • 0036624881 scopus 로고    scopus 로고
    • B-cell chronic lymphocytic leukemia cells express a surface membrane phenotype of activated, antigen-experienced B lymphocytes
    • Damle RN, Ghiotto F, Valetto A, et al: B-cell chronic lymphocytic leukemia cells express a surface membrane phenotype of activated, antigen-experienced B lymphocytes. Blood 99: 4087-4093, 2002.
    • (2002) Blood , vol.99 , pp. 4087-4093
    • Damle, R.N.1    Ghiotto, F.2    Valetto, A.3
  • 26
    • 0032851693 scopus 로고    scopus 로고
    • Bryostatin and CD40- Ligand enhance apoptosis resistance and induce expression of cell survival genes in B-cell chronic lymphocytic leukaemia
    • Kitada S, Zapata JM, Andreeff M, et al: Bryostatin and CD40- ligand enhance apoptosis resistance and induce expression of cell survival genes in B-cell chronic lymphocytic leukaemia. Br J Haematol 106: 995-1004, 1999.
    • (1999) Br J Haematol , vol.106 , pp. 995-1004
    • Kitada, S.1    Zapata, J.M.2    Andreeff, M.3
  • 28
    • 0026042148 scopus 로고
    • Hem-1, a potential membrane protein, with expression restricted to blood cells
    • Hromas R, Collins S, Raskind W, et al: Hem-1, a potential membrane protein, with expression restricted to blood cells. Biochim Biophys Acta 1090: 241-244, 1991.
    • (1991) Biochim Biophys Acta , vol.1090 , pp. 241-244
    • Hromas, R.1    Collins, S.2    Raskind, W.3
  • 29
    • 0028987180 scopus 로고
    • p53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic B-cell leukemias
    • Dohner H, Fischer K, Bentz M, et al: p53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic B-cell leukemias. Blood 85: 1580-1589, 1995.
    • (1995) Blood , vol.85 , pp. 1580-1589
    • Dohner, H.1    Fischer, K.2    Bentz, M.3
  • 30
    • 0026561988 scopus 로고
    • Mutations of the p53 gene in B-cell chronic lymphocytic leukemia: A report on 39 cases with cytogenetic analysis
    • Fenaux P, Preudhomme C, Lai JL, et al: Mutations of the p53 gene in B-cell chronic lymphocytic leukemia: a report on 39 cases with cytogenetic analysis. Leukemia 6: 246-250, 1992.
    • (1992) Leukemia , vol.6 , pp. 246-250
    • Fenaux, P.1    Preudhomme, C.2    Lai, J.L.3
  • 31
    • 0035437138 scopus 로고    scopus 로고
    • p53 dysfunction in B-cell chronic lymphocytic leukemia: Inactivation of ATM as an alternative to TP53 mutation
    • Pettitt AR, Sherrington PD, Stewart G, et al: p53 dysfunction in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative to TP53 mutation. Blood 98: 814-822, 2001.
    • (2001) Blood , vol.98 , pp. 814-822
    • Pettitt, A.R.1    Sherrington, P.D.2    Stewart, G.3
  • 32
    • 0033513587 scopus 로고    scopus 로고
    • Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia
    • Stankovic T, Weber P, Stewart G, et al: Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia. Lancet 353: 26-29, 1999.
    • (1999) Lancet , vol.353 , pp. 26-29
    • Stankovic, T.1    Weber, P.2    Stewart, G.3
  • 33
    • 0036096157 scopus 로고    scopus 로고
    • Ataxia telangiectasia mutated-deficient B-cell chronic lymphocytic leukemia occurs in pregerminal center cells and results in defective damage response and unrepaired chromosome damage
    • Stankovic T, Stewart GS, Fegan C, et al: Ataxia telangiectasia mutated-deficient B-cell chronic lymphocytic leukemia occurs in pregerminal center cells and results in defective damage response and unrepaired chromosome damage. Blood 99: 300-309, 2002.
    • (2002) Blood , vol.99 , pp. 300-309
    • Stankovic, T.1    Stewart, G.S.2    Fegan, C.3
  • 34
    • 0036624880 scopus 로고    scopus 로고
    • Down-regulation of candidate tumor suppressor genes within chromosome band 13q14.3 is independent of the DNA methylation pattern in Bcell chronic lymphocytic leukemia
    • Mertens D, Wolf S, Schroeter P, et al: Down-regulation of candidate tumor suppressor genes within chromosome band 13q14.3 is independent of the DNA methylation pattern in Bcell chronic lymphocytic leukemia. Blood 99: 4116-4121, 2002.
    • (2002) Blood , vol.99 , pp. 4116-4121
    • Mertens, D.1    Wolf, S.2    Schroeter, P.3
  • 35
    • 0141453649 scopus 로고    scopus 로고
    • RFP2, c13ORF1, and FAM10A4 are the most likely tumor suppressor gene candidates for B-cell chronic lymphocytic leukemia
    • Van Everdink WJ, Baranova A, Lummen C, et al: RFP2, c13ORF1, and FAM10A4 are the most likely tumor suppressor gene candidates for B-cell chronic lymphocytic leukemia. Cancer Genet Cytogenet 146: 48-57, 2003.
    • (2003) Cancer Genet Cytogenet , vol.146 , pp. 48-57
    • Van Everdink, W.J.1    Baranova, A.2    Lummen, C.3
  • 36
    • 0032540514 scopus 로고    scopus 로고
    • A cosmid and cDNA fine physical map of a human chromosome 13q14 region frequently lost in B-cell chronic lymphocytic leukemia and identification of a new putative tumor suppressor gene, Leu5
    • Kapanadze B, Kashuba V, Baranova A, et al: A cosmid and cDNA fine physical map of a human chromosome 13q14 region frequently lost in B-cell chronic lymphocytic leukemia and identification of a new putative tumor suppressor gene, Leu5. FEBS Lett 426: 266-270, 1998.
    • (1998) FEBS Lett , vol.426 , pp. 266-270
    • Kapanadze, B.1    Kashuba, V.2    Baranova, A.3
  • 37
    • 0038724274 scopus 로고    scopus 로고
    • Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways
    • Matsuda A, Suzuki Y, Honda G, et al: Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. Oncogene 22: 3307-3318, 2003.
    • (2003) Oncogene , vol.22 , pp. 3307-3318
    • Matsuda, A.1    Suzuki, Y.2    Honda, G.3
  • 38
    • 4444339751 scopus 로고    scopus 로고
    • ATM and ataxia telangiectasia
    • McKinnon PJ: ATM and ataxia telangiectasia. EMBO Rep 5: 772-776, 2004.
    • (2004) EMBO Rep , vol.5 , pp. 772-776
    • McKinnon, P.J.1
  • 39
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: Safeguarding genome integrity
    • Shiloh Y: ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer 3: 155-168, 2003.
    • (2003) Nat Rev Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 40
    • 0033568552 scopus 로고    scopus 로고
    • ATM is upregulated during the mitogenic response in peripheral blood mononuclear cells
    • Fukao T, Kaneko H, Birrell G, et al: ATM is upregulated during the mitogenic response in peripheral blood mononuclear cells. Blood 94: 1998-2006, 1999.
    • (1999) Blood , vol.94 , pp. 1998-2006
    • Fukao, T.1    Kaneko, H.2    Birrell, G.3
  • 41
    • 0035937841 scopus 로고    scopus 로고
    • Epidermal growth factor sensitizes cells to ionizing radiation by down-regulating protein mutated in ataxia-telangiectasia
    • Gueven N, Keating KE, Chen P, et al: Epidermal growth factor sensitizes cells to ionizing radiation by down-regulating protein mutated in ataxia-telangiectasia. J Biol Chem 276: 8884-8891, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 8884-8891
    • Gueven, N.1    Keating, K.E.2    Chen, P.3
  • 42
    • 0042346052 scopus 로고    scopus 로고
    • Variations in ATM protein expression during normal lymphoid differentiation and among B-cell-derived neoplasias
    • Starczynski J, Simmons W, Flavell JR, et al: Variations in ATM protein expression during normal lymphoid differentiation and among B-cell-derived neoplasias. Am J Pathol 163: 423-432, 2003.
    • (2003) Am J Pathol , vol.163 , pp. 423-432
    • Starczynski, J.1    Simmons, W.2    Flavell, J.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.