Population pharmacokinetic/pharmacodynamic modelling of the analgesic effects of tramadol in pediatrics

Pharmaceutical Research

Volumn 23, Issue 9, 2006, Pages 2014-2023

  Garrido, María J ^a   Habre, Walid ^b   Rombout, Ferdinand ^c   Trocóniz, Iñaki F ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b Geneva Children's Hospital   (Switzerland)

^c GRÜNENTHAL GMBH   (Germany)

Author keywords

Children; NONMEM; Population pharmacokinetic pharmacodynamic modelling; Tramadol

Indexed keywords

NARCOTIC ANALGESIC AGENT; TRAMADOL;

ALGORITHM; ARTICLE; BODY WEIGHT; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CRYING; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE; HUMAN; MALE; METABOLISM; MOVEMENT (PHYSIOLOGY); PHYSIOLOGY; POPULATION; POSTOPERATIVE PAIN; PREDICTION AND FORECASTING; PRESCHOOL CHILD; PSYCHOLOGICAL ASPECT; RANDOMIZED CONTROLLED TRIAL; STATISTICAL ANALYSIS; STATISTICAL MODEL;

ALGORITHMS; ANALGESICS, OPIOID; BODY WEIGHT; CHILD; CHILD, PRESCHOOL; CRYING; DATA INTERPRETATION, STATISTICAL; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MODELS, STATISTICAL; MOVEMENT; PAIN, POSTOPERATIVE; POPULATION; PREDICTIVE VALUE OF TESTS; TRAMADOL;

EID: 33750603989     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-006-9049-7     Document Type: Article

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