Sphingosine kinase-1 is cleaved by cathepsin B in vitro: Identification of the initial cleavage sites for the protease

FEBS Letters

Volumn 580, Issue 26, 2006, Pages 6047-6054

  Taha, Tarek A ^a   El Alwani, Mazen ^a   Hannun, Yusuf A ^b   Obeid, Lina M ^b  

^a RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Cathepsin B; Proteases; Sphingosine kinase

Indexed keywords

ARGININE; CATHEPSIN B; HISTIDINE; PROTEINASE; SPHINGOSINE KINASE 1; TYROSINE;

ARTICLE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION;

AMINO ACIDS, BASIC; ARGININE; BINDING SITES; CATHEPSIN B; CELL LINE, TUMOR; HISTIDINE; HUMANS; MUTAGENESIS, SITE-DIRECTED; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); TRANSFECTION;

EID: 33750509678     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.09.070     Document Type: Article

References (27)

1. Johnson D.E. Noncaspase proteases in apoptosis. Leukemia 14 (2000) 1695-1703
2. Turk V., Turk B., and Turk D. Lysosomal cysteine proteases: facts and opportunities. EMBO J. 20 (2001) 4629-4633
3. Polgar L., and Csoma C. Dissociation of ionizing groups in the binding cleft inversely controls the endo- and exopeptidase activities of cathepsin B. J. Biol. Chem. 262 (1987) 14448-14453
4. Turk B., Turk D., and Turk V. Lysosomal cysteine proteases: more than scavengers. Biochim. Biophys. Acta 1477 (2000) 98-111
5. Kominami E., Ueno T., Muno D., and Katunuma N. The selective role of cathepsins B and D in the lysosomal degradation of endogenous and exogenous proteins. FEBS Lett. 287 (1991) 189-192
6. Cavallo-Medved D., Mai J., Dosescu J., Sameni M., and Sloane B.F. Caveolin-1 mediates the expression and localization of cathepsin B, pro-urokinase plasminogen activator and their cell-surface receptors in human colorectal carcinoma cells. J. Cell Sci. 118 (2005) 1493-1503
7. Roshy S., Sloane B.F., and Moin K. Pericellular cathepsin B and malignant progression. Cancer Metastasis Rev. 22 (2003) 271-286
8. Guo M., Mathieu P.A., Linebaugh B., Sloane B.F., and Reiners Jr. J.J. Phorbol ester activation of a proteolytic cascade capable of activating latent transforming growth factor-betaL a process initiated by the exocytosis of cathepsin B. J. Biol. Chem. 277 (2002) 14829-14837
9. Koblinski J.E., Dosescu J., Sameni M., Moin K., Clark K., and Sloane B.F. Interaction of human breast fibroblasts with collagen I increases secretion of procathepsin B. J. Biol. Chem. 277 (2002) 32220-32227
10. Sinha A.A., Jamuar M.P., Wilson M.J., Rozhin J., and Sloane B.F. Plasma membrane association of cathepsin B in human prostate cancer: biochemical and immunogold electron microscopic analysis. Prostate 49 (2001) 172-184
11. Sameni M., Elliott E., Ziegler G., Fortgens P.H., Dennison C., and Sloane B.F. Cathepsin B and D are localized at the surface of human breast cancer cells. Pathol. Oncol. Res. 1 (1995) 43-53
12. Muntener K., Zwicky R., Csucs G., Rohrer J., and Baici A. Exon skipping of cathepsin B: mitochondrial targeting of a lysosomal peptidase provokes cell death. J. Biol. Chem. 279 (2004) 41012-41017
13. Mehtani S., Gong Q., Panella J., Subbiah S., Peffley D.M., and Frankfater A. In vivo expression of an alternatively spliced human tumor message that encodes a truncated form of cathepsin B. Subcellular distribution of the truncated enzyme in COS cells. J. Biol. Chem. 273 (1998) 13236-13244
14. Jaattela M. Multiple cell death pathways as regulators of tumour initiation and progression. Oncogene 23 (2004) 2746-2756
15. Stoka V., et al. Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route. J. Biol. Chem. 276 (2001) 3149-3157
16. Cirman T., Oresic K., Mazovec G.D., Turk V., Reed J.C., Myers R.M., Salvesen G.S., and Turk B. Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins. J. Biol. Chem. 279 (2004) 3578-3587
17. Guicciardi M.E., Deussing J., Miyoshi H., Bronk S.F., Svingen P.A., Peters C., Kaufmann S.H., and Gores G.J. Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c. J. Clin. Invest. 106 (2000) 1127-1137
18. Olivera A., Kohama T., Edsall L., Nava V., Cuvillier O., Poulton S., and Spiegel S. Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival. J. Cell Biol. 147 (1999) 545-558
19. Cuvillier O., and Levade T. Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria. Blood 98 (2001) 2828-2836
20. Taha T.A., Kitatani K., Bielawski J., Cho W., Hannun Y.A., and Obeid L.M. Tumor necrosis factor induces the loss of sphingosine kinase-1 by a cathepsin B-dependent mechanism. J. Biol. Chem. 280 (2005) 17196-17202
21. Johnson K.R., Becker K.P., Facchinetti M.M., Hannun Y.A., and Obeid L.M. PKC-dependent activation of sphingosine kinase 1 and translocation to the plasma membrane. Extracellular release of sphingosine-1-phosphate induced by phorbol 12-myristate 13-acetate (PMA). J. Biol. Chem. 277 (2002) 35257-35262
22. Olivera A., Barlow K.D., and Spiegel S. Assaying sphingosine kinase activity. Meth. Enzymol. 311 (2000) 215-223
23. Taha T.A., Kitatani K., Bielawski J., Cho W., Hannun Y.A., and Obeid L.M. TNF induces the loss of sphingosine kinase-1 by a cathepsin B dependent mechanism. J. Biol. Chem. 280 (2005) 17196-17202
24. Turk D., Guncar G., Podobnik M., and Turk B. Revised definition of substrate binding sites of papain-like cysteine proteases. Biol. Chem. 379 (1998) 137-147
25. Vancompernolle K., et al. Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity. FEBS Lett. 438 (1998) 150-158
26. Pitson S.M., et al. The nucleotide-binding site of human sphingosine kinase 1. J. Biol. Chem. 277 (2002) 49545-49553
27. Yokota S., Taniguchi Y., Kihara A., Mitsutake S., and Igarashi Y. Asp177 in C4 domain of mouse sphingosine kinase 1a is important for the sphingosine recognition. FEBS Lett. 578 (2004) 106-110