Comparative protein modeling and surface analysis of Leishmania sirtuin: A potential target for antileishmanial drug discovery

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 23, 2006, Pages 6013-6018

  Kadam, Rameshwar U ^a   Kiran, V M ^a   Roy, Nilanjan ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Homology modeling; Leishmania; MEPS; MOE; Sir2 NAD

Indexed keywords

NICOTINAMIDE; SIRTUIN;

AMINO ACID SEQUENCE; ARTICLE; COMPARATIVE STUDY; CRYSTAL STRUCTURE; DRUG DESIGN; ENZYME ACTIVATION; LEISHMANIA; LEISHMANIASIS; LIGAND BINDING; MOLECULAR MODEL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN TARGETING; STRUCTURAL HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CONSERVED SEQUENCE; ELECTROSTATICS; HUMANS; LEISHMANIA; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SIRTUINS; STRUCTURAL HOMOLOGY, PROTEIN; TRYPANOCIDAL AGENTS;

EID: 33750508503     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.08.128     Document Type: Article

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