All eight stereoisomeric D-glyconic-δ-lactams: Synthesis, conformational analysis, and evaluation as glycosidase inhibitors

Journal of Organic Chemistry

Volumn 65, Issue 16, 2000, Pages 4871-4882

  Nishimura, Yoshio ^a   Adachi, Hayamitsu ^a   Satoh, Takahiko ^a   Shitara, Eiki ^a   Nakamura, Hikaru ^a   Kojima, Fukiko ^a   Takeuchi, Tomio ^a  

^a INSTITUTE OF MICROBIAL CHEMISTRY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCONO DELTA LACTAM; GLYCOSIDASE INHIBITOR; LACTAM DERIVATIVE; LACTONE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; ENZYME INHIBITION; ISOMERISM; MOLECULAR MODEL; STEREOCHEMISTRY; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ALPHA-MANNOSIDASE; ANIMALS; ASPERGILLUS NIGER; BETA-GLUCOSIDASE; CARBOHYDRATE CONFORMATION; ENZYME INHIBITORS; GLYCOSIDE HYDROLASES; KINETICS; LACTAMS; MANNOSIDASES; MODELS, CHEMICAL; MODELS, MOLECULAR; SACCHAROMYCES CEREVISIAE; SNAILS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034637464     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo000141j     Document Type: Article

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