Thymidine kinase diversity in bacteria

Nucleosides, Nucleotides and Nucleic Acids

Volumn 25, Issue 9-11, 2006, Pages 1153-1158

  Sandrini, M P B ^a,b   Clausen, A R ^b   Munch Petersen, B ^c   Piškur, Jure ^b  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b LUND UNIVERSITY   (Sweden)

^c ROSKILDE UNIVERSITY   (Denmark)

Author keywords

Deoxyribonucleoside kinase; Evolution; Nucleic acids precursors; Nucleosides; Pyrimidines; Thymidine kinase

Indexed keywords

THYMIDINE KINASE;

ARTICLE; CONTROLLED STUDY; EUKARYOTE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; NONHUMAN; NUCLEOTIDE SEQUENCE; SPECIES DIVERSITY;

AMINO ACID SEQUENCE; BACTERIA; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEOSIDES; OPEN READING FRAMES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PHYLOGENY; PYRIMIDINES; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; THYMIDINE KINASE;

BACTERIA (MICROORGANISMS); EUKARYOTA; NEGIBACTERIA; POSIBACTERIA; PROKARYOTA;

EID: 33750436614     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770600894469     Document Type: Article

References (11)

1. Arner, E.S.J.; Eriksson, S. Mammalian Deoxyribonucleoside Kinases. Pharmacol. Therapeut. 1995, 67, 155-186.
2. Greco, O.; Dachs, G.U. Gene directed enzyme/prodrug therapy of cancer: historical appraisal and future prospectives. J. Cell Physiol. 2001, 187, 22-36.
3. Sandrini, M.P.; Piskur, J. Deoxyribonucleoside kinases: two enzyme families catalyze the same reaction. Trends Biochem. Sci. 2005, 30, 225-228.
4. Welin, M.; Kosinska, U.; Mikkelsen, N.E.; Carnrot, C.; Zhu, C.; Wang, L.; Eriksson, S.; Munch-Petersen, B.; Eklund, H. Structures of thymidine kinase 1 of human and mycoplasmic origin. Proc. Natl. Acad. Sci. USA 2004, 101, 17970-17975.
5. Knecht, W.; Sandrini, M.P.; Johansson, K.; Eklund, H.; Munch-Petersen, B.; Piskur, J. A few amino acid substitutions can convert deoxyribonucleoside kinase specificity from pyrimidines to purines. EMBO J. 2002, 21, 1873-1880.
6. Sabini, E.; Ort, S.; Monnerjahn, C.; Konrad, M.; Lavie, A. Structure of human dCK suggests strategies to improve anticancer and antiviral therapy. Nat. Struct. Biol. 2003, 10, 513-519.
7. Thompson, J.D.; Gibson, T.J.; Plewniak, F.; Jeanmougin, F.; Higgins, D.G. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic. Acids Res. 1997, 25, 4876-4882.
8. Van de Peer, Y.; De Wachter, R. TREECON for Windows: a software package for the construction and drawing of evolutionary trees for the Microsoft Windows environment. Comput. Appl. Biosci. 1994, 10, 569-570.
9. Guex, N.; Peitsch, M.C. SWISS-MOLDE and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis 1997, 18, 2714-2723.
10. Ahmad, S.; Selvapandiyan, A.; Bhatnagar, R.K. Phylogenetic analysis of Gram-positive bacteria based on grpE, encoded by the dnaK operon. Int. J. Syst. Evol. Microbiol 2000, 50(Pt. 5), 1761-1766.
11. Munch-Petersen, B.; Cloos, L.; Tyrsted, G.; Eriksson, S. Diverging substrate specificity of pure human thymidine kinases 1 and 2 against antiviral dideoxynucleosides. J. Biol. Chem. 1991, 266, 9032-9038.