메뉴 건너뛰기




Volumn 67, Issue 6, 2006, Pages 501-510

Viral proteinases: Targets of opportunity

Author keywords

Antiviral drugs; I7L; Proteinase inhibitors; Vaccinia virus

Indexed keywords

ABACAVIR; ACICLOVIR; ADEFOVIR DIPIVOXIL; AMANTADINE; ANTIVIRUS AGENT; CIDOFOVIR; DELAVIRDINE; DIDANOSINE; EFAVIRENZ; EMTRICITABINE; ENFUVIRTIDE; FOSCARNET; GANCICLOVIR; INDINAVIR; LAMIVUDINE; NEVIRAPINE; PENTAERYTHRITYL TETRANITRATE; PROTEINASE; PROTEINASE INHIBITOR; RIBAVIRIN; RIMANTADINE; RITONAVIR; SAQUINAVIR; STAVUDINE; TENOFOVIR; TRIFLURIDINE; UNINDEXED DRUG; VALACICLOVIR; ZALCITABINE; ZIDOVUDINE;

EID: 33750358280     PISSN: 02724391     EISSN: 10982299     Source Type: Journal    
DOI: 10.1002/ddr.20114     Document Type: Review
Times cited : (5)

References (68)
  • 1
    • 2642585575 scopus 로고    scopus 로고
    • Role of the 17 protein in proteolytic processing of vaccinia virus membrane and core components
    • Ansarah-Sobrinho C, Moss B. 2004a. Role of the 17 protein in proteolytic processing of vaccinia virus membrane and core components. J Virol 78:6335-6343.
    • (2004) J Virol , vol.78 , pp. 6335-6343
    • Ansarah-Sobrinho, C.1    Moss, B.2
  • 2
    • 2942639514 scopus 로고    scopus 로고
    • Vaccinia virus G1 protein, a predicted metalloprotease, is essential for morphogenesis of infectious virions but not for cleavage of major core proteins
    • Ansarah-Sobrinho C, Moss B. 2004b. Vaccinia virus G1 protein, a predicted metalloprotease, is essential for morphogenesis of infectious virions but not for cleavage of major core proteins. J Virol 78:6855-6863.
    • (2004) J Virol , vol.78 , pp. 6855-6863
    • Ansarah-Sobrinho, C.1    Moss, B.2
  • 3
    • 85085717718 scopus 로고    scopus 로고
    • Intrathecal cytarabine and bone marrow suppression
    • Barista I. 2000. Intrathecal cytarabine and bone marrow suppression. J Clin Oncol 18:2003-2004.
    • (2000) J Clin Oncol , vol.18 , pp. 2003-2004
    • Barista, I.1
  • 4
    • 84944052122 scopus 로고    scopus 로고
    • Barrett AJ, Rawlings ND, Woessner JF, editors. San Diego: Elsevier Academic Press
    • Barrett AJ, Rawlings ND, Woessner JF, editors. 2004. Handbook of proteolytic enzymes, 2nd ed. San Diego: Elsevier Academic Press.
    • (2004) Handbook of Proteolytic Enzymes, 2nd Ed.
  • 5
    • 0037416146 scopus 로고    scopus 로고
    • Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes
    • Bartosch B, Dubuisson J, Cosset FL. 2003. Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes. J Exp Med 197:633-642.
    • (2003) J Exp Med , vol.197 , pp. 633-642
    • Bartosch, B.1    Dubuisson, J.2    Cosset, F.L.3
  • 6
    • 12944268369 scopus 로고    scopus 로고
    • Conservation of amino acids in human rhinovirus 3C protease correlates with broad-spectrum antiviral activity of rupintrivir, a novel human rhinovirus 3C protease inhibitor
    • Binford SL, Maldonado F, Brothers MA, Weady PT, Zalman LS, Meador JW 3rd, Matthews DA, Patiek AK. 2005. Conservation of amino acids in human rhinovirus 3C protease correlates with broad-spectrum antiviral activity of rupintrivir, a novel human rhinovirus 3C protease inhibitor. Antimicrob Agents Chemother 49:619-626.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 619-626
    • Binford, S.L.1    Maldonado, F.2    Brothers, M.A.3    Weady, P.T.4    Zalman, L.S.5    Meador III, J.W.6    Matthews, D.A.7    Patiek, A.K.8
  • 7
    • 0038047695 scopus 로고    scopus 로고
    • Enfuvirtide approved for defusing HIV
    • Burton A. 2003. Enfuvirtide approved for defusing HIV Lancet Infect Dis 3:260.
    • (2003) Lancet Infect Dis , vol.3 , pp. 260
    • Burton, A.1
  • 8
    • 15544387353 scopus 로고    scopus 로고
    • A conditional-lethal vaccinia virus mutant demonstrates that the I7L gene product is required for virion morphogenesis
    • Byrd CM, Hruby DE. 2005a. A conditional-lethal vaccinia virus mutant demonstrates that the I7L gene product is required for virion morphogenesis. Virol J 2:4.
    • (2005) Virol J , vol.2 , pp. 4
    • Byrd, C.M.1    Hruby, D.E.2
  • 9
    • 24144481211 scopus 로고    scopus 로고
    • Development of an in vitro cleavage assay system to examine vaccinia virus I7L cysteine proteinase activity
    • Byrd CM, Hruby DE. 2005b. Development of an in vitro cleavage assay system to examine vaccinia virus I7L cysteine proteinase activity. Virol J 2:63.
    • (2005) Virol J , vol.2 , pp. 63
    • Byrd, C.M.1    Hruby, D.E.2
  • 10
    • 0036338018 scopus 로고    scopus 로고
    • The vaccinia virus I7L gene product is the core protein proteinase
    • Byrd CM, Bolken TC, Hruby DE. 2002. The vaccinia virus I7L gene product is the core protein proteinase. J Virol 76:8973-8976.
    • (2002) J Virol , vol.76 , pp. 8973-8976
    • Byrd, C.M.1    Bolken, T.C.2    Hruby, D.E.3
  • 11
    • 0141676552 scopus 로고    scopus 로고
    • Molecular dissection of the vaccinia virus I7L core protein proteinase
    • Byrd CM, Bolken TC, Hruby DE. 2003. Molecular dissection of the vaccinia virus I7L core protein proteinase. J Virol 77: 11279-11283.
    • (2003) J Virol , vol.77 , pp. 11279-11283
    • Byrd, C.M.1    Bolken, T.C.2    Hruby, D.E.3
  • 13
    • 33750306460 scopus 로고    scopus 로고
    • Vaccinia virus metalloproteinase
    • Barrett A, Rawlings N, Woessner J, editors. Amsterdam: Elsevier
    • Byrd CM, Bolken TC, Hruby DE. 2004b. Vaccinia virus metalloproteinase. In: Barrett A, Rawlings N, Woessner J, editors. Handbook of proteolytic enzymes, 2nd ed. Amsterdam: Elsevier.
    • (2004) Handbook of Proteolytic Enzymes, 2nd Ed.
    • Byrd, C.M.1    Bolken, T.C.2    Hruby, D.E.3
  • 14
    • 27644458571 scopus 로고    scopus 로고
    • Robust production of infectious hepatitis C virus (HCV) from stably HCV cDNA-transfected human hepatoma cells
    • Cai Z, Zhang C, Chang KS, Jiang J, Ahn BC, Wakita T, Liang TJ, Luo G. 2005. Robust production of infectious hepatitis C virus (HCV) from stably HCV cDNA-transfected human hepatoma cells. J Virol 79:13963-13973.
    • (2005) J Virol , vol.79 , pp. 13963-13973
    • Cai, Z.1    Zhang, C.2    Chang, K.S.3    Jiang, J.4    Ahn, B.C.5    Wakita, T.6    Liang, T.J.7    Luo, G.8
  • 15
    • 0028905697 scopus 로고
    • Development of antiviral therapy with alpha interferons: Promises, false hopes and accomplishments
    • Cantell K. 1995. Development of antiviral therapy with alpha interferons: promises, false hopes and accomplishments. Ann Med 27:23-28.
    • (1995) Ann Med , vol.27 , pp. 23-28
    • Cantell, K.1
  • 18
    • 33646131201 scopus 로고    scopus 로고
    • Smallpox vaccinations and adverse events
    • Cohen HW, Gould RM, Sidel VW. 2006. Smallpox vaccinations and adverse events. JAMA 295:1897-1898.
    • (2006) JAMA , vol.295 , pp. 1897-1898
    • Cohen, H.W.1    Gould, R.M.2    Sidel, V.W.3
  • 20
    • 0027138172 scopus 로고
    • Expression of virus-encoded proteinases: Functional and structural similarities with cellular enzymes
    • Dougherty WG, Semler BL. 1993. Expression of virus-encoded proteinases: functional and structural similarities with cellular enzymes. Microbiol Rev 57:781-822.
    • (1993) Microbiol Rev , vol.57 , pp. 781-822
    • Dougherty, W.G.1    Semler, B.L.2
  • 21
    • 0346848719 scopus 로고    scopus 로고
    • Safety and efficacy evaluation of pleconaril for treatment of the common cold
    • Fleischer R, Laessig K. 2003. Safety and efficacy evaluation of pleconaril for treatment of the common cold. Clin Infect Dis 37:1722.
    • (2003) Clin Infect Dis , vol.37 , pp. 1722
    • Fleischer, R.1    Laessig, K.2
  • 24
    • 0032600559 scopus 로고    scopus 로고
    • T-20: First of a new class of anti-HIV drugs
    • Hanna L. 1999. T-20: first of a new class of anti-HIV drugs. Beta 12:7-8.
    • (1999) Beta , vol.12 , pp. 7-8
    • Hanna, L.1
  • 25
    • 0344012008 scopus 로고    scopus 로고
    • Phase II, randomized, double-blind, placebo-controlled studies of ruprintrivir nasal spray 2-percent suspension for prevention and treatment of experimentally induced rhinovirus colds in healthy volunteers
    • Hayden FG, Turner RB, Gwaltney JM, Chi-Burris K, Gersten M, Hsyu P, Patick AK, Smith GJ 3rd, Zalman LS. 2003. Phase II, randomized, double-blind, placebo-controlled studies of ruprintrivir nasal spray 2-percent suspension for prevention and treatment of experimentally induced rhinovirus colds in healthy volunteers. Antimicrob Agents Chemother 47:3907-3916.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 3907-3916
    • Hayden, F.G.1    Turner, R.B.2    Gwaltney, J.M.3    Chi-Burris, K.4    Gersten, M.5    Hsyu, P.6    Patick, A.K.7    Smith III, G.J.8    Zalman, L.S.9
  • 26
    • 4444331796 scopus 로고    scopus 로고
    • The vaccinia virus G1L putative metalloproteinase is essential for viral replication in vivo
    • Hedengren-Olcott M, Byrd CM, Watson J, Hruby DE. 2004. The vaccinia virus G1L putative metalloproteinase is essential for viral replication in vivo. J Virol 78:9947-9953.
    • (2004) J Virol , vol.78 , pp. 9947-9953
    • Hedengren-Olcott, M.1    Byrd, C.M.2    Watson, J.3    Hruby, D.E.4
  • 27
    • 0026511549 scopus 로고
    • The role of proteolytic processing in the morphogenesis of virus particles
    • Hellen CU, Wimmer E. 1992. The role of proteolytic processing in the morphogenesis of virus particles. Experientia 48:201-215.
    • (1992) Experientia , vol.48 , pp. 201-215
    • Hellen, C.U.1    Wimmer, E.2
  • 28
    • 0014322011 scopus 로고
    • Sensitivity of herpes simplex virus, vaccinia virus, and adenoviruses to deoxyribonucleic acid inhibitors and thiosemicarbazones in a plaque suppression test
    • Herrmann EC Jr. 1968. Sensitivity of herpes simplex virus, vaccinia virus, and adenoviruses to deoxyribonucleic acid inhibitors and thiosemicarbazones in a plaque suppression test. Appl Microbiol 16:1151-1155.
    • (1968) Appl Microbiol , vol.16 , pp. 1151-1155
    • Herrmann Jr., E.C.1
  • 33
    • 0026638898 scopus 로고
    • Hydroxyurea induces apoptosis and regular DNA fragmentation in a Burkitt's lymphoma cell line
    • Johnson CA, Forster TH, Winterford CM, Allan DJ. 1992. Hydroxyurea induces apoptosis and regular DNA fragmentation in a Burkitt's lymphoma cell line. Biochim Biophys Acta 1136:1-4.
    • (1992) Biochim Biophys Acta , vol.1136 , pp. 1-4
    • Johnson, C.A.1    Forster, T.H.2    Winterford, C.M.3    Allan, D.J.4
  • 35
    • 33646177011 scopus 로고    scopus 로고
    • Smallpox antiviral drug development: Satisfying the animal efficacy rule
    • Jordan R, Hruby D. 2006. Smallpox antiviral drug development: satisfying the animal efficacy rule. Expert Rev Anti Infect Ther 4:277-289.
    • (2006) Expert Rev Anti Infect Ther , vol.4 , pp. 277-289
    • Jordan, R.1    Hruby, D.2
  • 36
    • 33646188826 scopus 로고    scopus 로고
    • Generation of infectious hepatitis C virus in immortalized human hepatocytes
    • Kanda T, Basu A, Steele R, Wakita T, Ryerse JS, Ray R, Ray RB. 2006. Generation of infectious hepatitis C virus in immortalized human hepatocytes. J Virol 80:4633-4639.
    • (2006) J Virol , vol.80 , pp. 4633-4639
    • Kanda, T.1    Basu, A.2    Steele, R.3    Wakita, T.4    Ryerse, J.S.5    Ray, R.6    Ray, R.B.7
  • 37
    • 0025017237 scopus 로고
    • Viral proteinases: Weakness in strength
    • Kay J, Dunn BM. 1990. Viral proteinases: weakness in strength. Biochim Biophys Acta 1048:1-18.
    • (1990) Biochim Biophys Acta , vol.1048 , pp. 1-18
    • Kay, J.1    Dunn, B.M.2
  • 40
    • 0030430035 scopus 로고    scopus 로고
    • Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes
    • Kumar GN, Rodrigues AD, Buko AM, Denissen JF. 1996. Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes. J Pharmacol Exp Ther 277:423-431.
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 423-431
    • Kumar, G.N.1    Rodrigues, A.D.2    Buko, A.M.3    Denissen, J.F.4
  • 41
    • 0031968815 scopus 로고    scopus 로고
    • Functional role of hepatitis C virus chimeric glycoproteins in the infectivity of pseudotyped virus
    • Lagging LM, Meyer K, Owens RJ, Ray R. 1998. Functional role of hepatitis C virus chimeric glycoproteins in the infectivity of pseudotyped virus. J Virol 72:3539-3546.
    • (1998) J Virol , vol.72 , pp. 3539-3546
    • Lagging, L.M.1    Meyer, K.2    Owens, R.J.3    Ray, R.4
  • 44
    • 0034628448 scopus 로고    scopus 로고
    • Protease inhibitors: Current status and future prospects
    • Leung D, Abbenante G, Fairlie DP. 2000. Protease inhibitors: current status and future prospects. J Med Chem 43:305-341.
    • (2000) J Med Chem , vol.43 , pp. 305-341
    • Leung, D.1    Abbenante, G.2    Fairlie, D.P.3
  • 46
    • 0024463578 scopus 로고
    • A consensus sequence for substrate hydrolysis by rhinovirus 3C proteinase
    • Long AC, Orr DC, Cameron JM, Dunn BM, Kay J. 1989. A consensus sequence for substrate hydrolysis by rhinovirus 3C proteinase. FEBS Lett 258:75-78.
    • (1989) FEBS Lett , vol.258 , pp. 75-78
    • Long, A.C.1    Orr, D.C.2    Cameron, J.M.3    Dunn, B.M.4    Kay, J.5
  • 47
    • 0030592514 scopus 로고    scopus 로고
    • The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site
    • Love RA, Parge HE, Wickersham JA, Hostomsky Z, Habuka N, Moomaw EW, Adachi T, Hostomska Z. 1996. The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site. Cell 87:331-342.
    • (1996) Cell , vol.87 , pp. 331-342
    • Love, R.A.1    Parge, H.E.2    Wickersham, J.A.3    Hostomsky, Z.4    Habuka, N.5    Moomaw, E.W.6    Adachi, T.7    Hostomska, Z.8
  • 48
    • 15244352597 scopus 로고    scopus 로고
    • Inhibitors of virus replication: Recent developments and prospects
    • Magden T, Kaariainen L, Ahola T. 2005. Inhibitors of virus replication: recent developments and prospects. Appl Microbiol Biotechnol 66:612-621.
    • (2005) Appl Microbiol Biotechnol , vol.66 , pp. 612-621
    • Magden, T.1    Kaariainen, L.2    Ahola, T.3
  • 49
    • 0035080791 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of prodrug-type anti-HIV agents: Ester conjugates of carboxylic acid-containing dipeptide HIV protease inhibitors and a reverse trauscriptase inhibitor
    • Matsumoto H, Matsuda T, Nakata S, Mitoguchi T, Kimura T, Hayashi Y, Kiso Y. 2001. Synthesis and biological evaluation of prodrug-type anti-HIV agents: ester conjugates of carboxylic acid-containing dipeptide HIV protease inhibitors and a reverse trauscriptase inhibitor. Bioorg Med Chem 9:417-430.
    • (2001) Bioorg Med Chem , vol.9 , pp. 417-430
    • Matsumoto, H.1    Matsuda, T.2    Nakata, S.3    Mitoguchi, T.4    Kimura, T.5    Hayashi, Y.6    Kiso, Y.7
  • 51
    • 0023198435 scopus 로고
    • Clinical use of antiviral drugs
    • Nahata MC. 1987. Clinical use of antiviral drugs. Drug Intell Clin Pharm 21:399-405.
    • (1987) Drug Intell Clin Pharm , vol.21 , pp. 399-405
    • Nahata, M.C.1
  • 55
    • 24344496912 scopus 로고    scopus 로고
    • Emerging drug targets for antiretroviral therapy
    • Reeves JD, Piefer AJ. 2005. Emerging drug targets for antiretroviral therapy. Drugs 65:1747-1766.
    • (2005) Drugs , vol.65 , pp. 1747-1766
    • Reeves, J.D.1    Piefer, A.J.2
  • 56
    • 0642340674 scopus 로고    scopus 로고
    • US FDA approves new class of HIV therapeutics
    • Robertson D. 2003. US FDA approves new class of HIV therapeutics. Nat Biotechnol 21:470-471.
    • (2003) Nat Biotechnol , vol.21 , pp. 470-471
    • Robertson, D.1
  • 57
    • 0013899017 scopus 로고
    • The effect of hydroxyurea on virus development. II. Vaccinia virus
    • Rosenkranz HS, Rose HM, Morgan C, Hsu KC. 1966. The effect of hydroxyurea on virus development. II. Vaccinia virus. Virology 28:510-519.
    • (1966) Virology , vol.28 , pp. 510-519
    • Rosenkranz, H.S.1    Rose, H.M.2    Morgan, C.3    Hsu, K.C.4
  • 58
    • 28844473221 scopus 로고    scopus 로고
    • Neurologic adverse events associated with smallpox vaccination in the United States, 2002-2004
    • Sejvar JJ, Labutta RJ, Chapman LE, Grabenstein JD, Iskander J, Lane JM. 2005. Neurologic adverse events associated with smallpox vaccination in the United States, 2002-2004. Jama 294: 2744-2750.
    • (2005) Jama , vol.294 , pp. 2744-2750
    • Sejvar, J.J.1    Labutta, R.J.2    Chapman, L.E.3    Grabenstein, J.D.4    Iskander, J.5    Lane, J.M.6
  • 59
    • 0038476114 scopus 로고    scopus 로고
    • HIV infection: A new drug and new costs
    • Steinbrook R. 2003. HIV infection: a new drug and new costs. N Engl J Med 348:2171-2172.
    • (2003) N Engl J Med , vol.348 , pp. 2171-2172
    • Steinbrook, R.1
  • 62
    • 0029391210 scopus 로고
    • Update on HIV protease inhibitors
    • 88
    • Vella S. 1995. Update on HIV protease inhibitors. AIDS Clin Care 7:79-82, 88.
    • (1995) AIDS Clin Care , vol.7 , pp. 79-82
    • Vella, S.1
  • 63
    • 26944452043 scopus 로고    scopus 로고
    • PEGylation, successful approach to drug delivery
    • Veronese FM, Pasut G. 2005. PEGylation, successful approach to drug delivery. Drug Discov Today 10:1451-1458.
    • (2005) Drug Discov Today , vol.10 , pp. 1451-1458
    • Veronese, F.M.1    Pasut, G.2
  • 65
    • 0027948137 scopus 로고
    • A transcriptionally controlled trans-processing assay: Putative identification of a vaccinia virus-encoded proteinase which cleaves precursor protein P25 K
    • Whitehead SS, Hruby DE. 1994. A transcriptionally controlled trans-processing assay: putative identification of a vaccinia virus-encoded proteinase which cleaves precursor protein P25 K. J Virol 68:7603-7608.
    • (1994) J Virol , vol.68 , pp. 7603-7608
    • Whitehead, S.S.1    Hruby, D.E.2
  • 67
    • 0022479766 scopus 로고
    • Protease gene structure and env gene variability of the AIDS virus
    • Yasunaga T, Sagata N, Ikawa Y. 1986. Protease gene structure and env gene variability of the AIDS virus. FEBS Lett 199: 145-150.
    • (1986) FEBS Lett , vol.199 , pp. 145-150
    • Yasunaga, T.1    Sagata, N.2    Ikawa, Y.3
  • 68
    • 33144471074 scopus 로고    scopus 로고
    • Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells
    • Yi M, Villanueva RA, Thomas DL, Wakita T, Lemon SM. 2006. Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells. Proc Natl Acad Sci USA 103:2310-2315.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2310-2315
    • Yi, M.1    Villanueva, R.A.2    Thomas, D.L.3    Wakita, T.4    Lemon, S.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.