Specific and randomly derived immunoactive peptide mimotopes of mycobacterial antigens

Clinical and Vaccine Immunology

Volumn 13, Issue 10, 2006, Pages 1143-1154

  Sharma, Archna ^a   Saha, Abhik ^a   Bhattacharjee, Surajit ^a   Majumdar, Subrata ^a   Das Gupta, Sujoy K ^a  

^a BOSE INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; CYTOKINE; EPITOPE; INTERLEUKIN 12; LIPOARABINOMANNAN; MIMOTOPE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CS 35; MYCOBACTERIUM ANTIGEN; PEPTIDE LIBRARY; POLYCLONAL ANTISERUM; RABBIT ANTISERUM; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN ANTIBODY REACTION; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIAGNOSTIC VALUE; DISSOCIATION CONSTANT; DOT HYBRIDIZATION; IMMUNOMODULATION; IMMUNOTHERAPY; MACROPHAGE; MOUSE; MYCOBACTERIUM BOVIS; NONHUMAN; PEPTIDE ANALYSIS; PHAGE DISPLAY; PRIORITY JOURNAL; TUBERCULOSIS;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIOPHAGE M13; EPITOPES; HUMANS; IMMUNOLOGIC FACTORS; MOLECULAR MIMICRY; MYCOBACTERIUM BOVIS; MYCOBACTERIUM INFECTIONS; PEPTIDE LIBRARY; PEPTIDES; RABBITS;

EID: 33750317417     PISSN: 15566811     EISSN: None     Source Type: Journal    
DOI: 10.1128/CVI.00127-06     Document Type: Article

References (60)

1. Andersen, P. 2001. TB vaccines: progress and problems. Trends Immunol. 22:160-168.
2. Barnes, P. F., D. Chatterjee, J. S. Abrams, S. Lu, E. Wang, M. Yamamura, P. J. Brennan, and R. L. Modlin. 1992. Cytokine production induced by Mycobacterium tuberculosis lipoarabinomannan. Relationship to chemical structure. J. Immunol. 149:541-547.
3. Barry, C. E., III. 2001. Interpreting cell wall 'virulence factors' of Mycobacterium tuberculosis. Trends Microbiol. 9:237-241.
4. Besra, G. S., and D. Chatterjee. 1994. Lipids and carbohydrates of Mycobacterium tuberculosis, p. 285-306. In B. R. Bloom (ed.), Tuberculosis: pathogenesis, protection, and control. American Society for Microbiology, Washington, D.C.
5. Bothamley, G. H. 1995. Serological diagnosis of tuberculosis. Eur. Respir. J. Suppl. 20:676s-688s.
6. Brandt, L., M. Elhay, I. Rosenkrands, E. B. Lindblad, and P. Andersen. 2000. ESAT-6 subunit vaccination against Mycobacterium tuberculosis. Infect. Immun. 68:791-795.
7. Brennan, P. J., and H. Nikaido. 1995. The envelope of mycobacteria. Annu. Rev. Biochem. 64:29-63.
8. Chatterjee, D. 1997. The mycobacterial cell wall: structure, biosynthesis and sites of drug action. Curr. Opin. Chem. Biol. 1:579-588.
9. Chatterjee, D., A. D. Roberts, K. Lowell, P. J. Brennan, and I. M. Orme. 1992. Structural basis of capacity of lipoarabinomannan to induce secretion of tumor necrosis factor. Infect. Immun. 60:1249-1253.
10. Chatterjee, D., K. Lowell, B. Rivoire, M. R. McNeil, and P. J. Brennan. 1992. Lipoarabinomannan of Mycobacterium tuberculosis. Capping with mannosyl residues in some strains. J. Biol. Chem. 267:6234-6239.
11. Chiang, I. H., J. Suo, K. J. Bai, T. P. Lin, K. T. Luh, C. J. Yu, and P. C. Yang. 1997. Serodiagnosis of tuberculosis. A study comparing three specific mycobacterial antigens. Am. J. Respir. Crit. Care Med. 156:906-911.
12. Cunto-Amesty, G., P. Luo, B. Monzavi-Karbassi, A. Lees, J. Alexander, M. F. del Guercio, M. H. Nahm, C. Artaud, J. Stanley, and T. Kieber-Emmons. 2003. Peptide mimotopes as prototypic templates of broad-spectrum surrogates of carbohydrate antigens. Cell. Mol. Biol. 49:245-254.
13. Daniel, T. M., and S. M. Debanne. 1987. The serodiagnosis of tuberculosis and other mycobacterial diseases by enzyme-linked immunosorbent assay. Am. Rev. Respir. Dis. 135:1137-1151.
14. + T-cell epitopic repertoire broader than that stimulated by Mycobacterium tuberculosis H37Rv infection. Infect. Immun. 66:1527-1533.
15. Dybwad, A., O. Forre, J. Kjeldsen-Kragh, J. B. Natvig, and M. Sioud. 1993. Identification of new B cell epitopes in the sera of rheumatoid arthritis patients using a random nanopeptide phage library. Eur. J. Immunol. 23: 3189-3193.
16. Ehlers, M. R., and M. Daffe. 1998. Interactions between Mycobacterium tuberculosis and host cells: are mycobacterial sugars the key? Trends Microbiol. 6:328-335.
17. Ewer, K., P. Cockle, S. Gordon, H. Mansoor, M. Govaerts, K. Walravens, S. Marche, G. Hewinson, and M. Vordermeier. 2006. Antigen mining with iterative genome screens identifies novel diagnostics for the Mycobacterium tuberculosis complex. Clin. Vaccine Immunol. 13:90-97.
18. Gevorkian, G., E. Segura, G. Acero, J. P. Palma, C. Espitia, K. Manoutcharian, and L. M. Lopez-Marin. 2005. Peptide mimotopes of Mycobacterium tuberculosis carbohydrate immunodeterminants. Biochem. J. 387:411-417.
19. Gutman, G. A., and G. W. Hatfield. 1989. Nonrandom utilization of codon pairs in Escherichia coli. Proc. Natl. Acad. Sci. USA 86:3699-3703.
20. Hamasur, B., G. Kallenius, and S. B. Svenson. 1999. A new rapid and simple method for large-scale purification of mycobacterial lipoarabinomannan. FEMS Immunol. Med. Microbiol. 24:11-17.
21. Hamasur, B., J. Bruchfeld, M. Haile, A. Pawlowski, B. Bjorvatn, G. Kallenius, and S. B. Svenson. 2001. Rapid diagnosis of tuberculosis by detection of mycobacterial lipoarabinomannan in urine. J. Microbiol. Methods 45:41-52.
22. Hetland, G., H. G. Wiker, K. Hogasen, B. Hamasur, S. B. Svenson, and M. Harboe. 1998. Involvement of antilipoarabinomannan antibodies in classical complement activation in tuberculosis. Clin. Diagn. Lab. Immunol. 5:211-218.
23. Horwitz, M. A., B. W. Lee, B. J. Dillon, and G. Harth. 1995. Protective immunity against tuberculosis induced by vaccination with major extracellular proteins of Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. USA 92: 1530-1534.
24. Johnson, P. D., R. L. Stuart, M. L. Grayson, D. Olden, A. Clancy, P. Ravn, P. Andersen, W. J. Britton, and J. S. Rothel. 1999. Tuberculin-purified protein derivative-, MPT-64-, and ESAT-6-stimulated gamma interferon responses in medical students before and after Mycobacterium bovis BCG vaccination and in patients with tuberculosis. Clin. Diagn. Lab. Immunol. 6:934-937.
25. Jolley, M. E., S. Rudikoff, M. Potter, and C. P. Glaudemans. 1973. Spectral changes on binding of oligosaccharides to murine immunoglobulin A myeloma proteins. Biochemistry 12:3039-3044.
26. Julian, E., L. Matas, A. Perez, J. Alcaide, M. A. Laneelle, and M. Luquin. 2002. Serodiagnosis of tuberculosis: comparison of immunoglobulin A (IgA) response to sulfolipid I with IgG and IgM responses to 2,3-diacyltrehalose, 2,3,6-triacyltrehalose, and cord factor antigens. J. Clin. Microbiol. 40:3782-3788.
27. Julian, E., L. Matas, J. Alcaide, and M. Luquin. 2004. Comparison of antibody responses to a potential combination of specific glycolipids and proteins for test sensitivity improvement in tuberculosis serodiagnosis. Clin. Diagn. Lab. Immunol. 11:70-76.
28. Kaur, D., T. L. Lowary, V. D. Vissa, D. C. Crick, and P. J. Brennan. 2002. Characterization of the epitope of anti-lipoarabinomannan antibodies as the terminal hexaarabinofuranosyl motif of mycobacterial arabinans. Microbiology 148:3049-3057.
29. Kitada, S., R. Maekura, N. Toyoshima, N. Fujiwara, I. Yano, T. Ogura, M. Ito, and K. Kobayashi. 2002. Serodiagnosis of pulmonary disease due to Mycobacterium avium complex with an enzyme immunoassay that uses a mixture of glycopeptidolipid antigens. Clin. Infect. Dis. 35:1328-1335.
30. Kouzmitcheva, G. A., V. A. Petrenko, and G. P. Smith. 2001. Identifying diagnostic peptides for Lyme disease through epitope discovery. Clin. Diagn. Lab. Immunol. 8:150-160.
31. Lowry, O. H., N. J. Rosebrough, A. L. Farr, and R. J. Randall. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:265-275.
32. Lyashchenko, K., R. Colangeli, M. Houde, H. Al Jahdali, D. Menzies, and M. L. Gennaro. 1998. Heterogeneous antibody responses in tuberculosis. Infect. Immun. 66:3936-3940.
33. Mintz, P. J., J. Kim, K. A. Do, X. Wang, R. G. Zinner, M. Cristofanilli, M. A. Arap, W. K. Hong, P. Troncoso, C. J. Logothetis, R. Pasqualini, and W. Arap. 2003. Fingerprinting the circulating repertoire of antibodies from cancer patients. Nat. Biotechnol. 21:57-63.
34. Noya, O., and B. Alarcon de Noya. 1998. The multiple antigen blot assay (MABA): a simple immunoenzymatic technique for simultaneous screening of multiple antigens. Immunol. Lett. 63:53-56.
35. Onyebujoh, P., A. Zumla, I. Ribeiro, R. Ruslomjee, P. Mwaba, M. Gomes, and J. M. Grange. 2005. Treatment of tuberculosis: present status and future prospects. Bull. W. H. O. 83:857-865.
36. Parra, M., N. Cadieux, T. Pickett, V. Dheenadhayalan, and M. J. Brennan. 2006. A PE protein expressed by Mycobacterium avium is an effective T-cell immunogen. Infect. Immun. 74:786-789.
37. Petrenko, V. A., G. P. Smith, X. Gong, and T. Quinn. 1996. A library of organic landscapes on filamentous phage. Protein Eng. 9:797-801.
38. Pieters, J. 2001. Entry and survival of pathogenic mycobacteria in macrophages. Microbes Infect. 3:249-255.
39. Pollet, R., and H. Edelhoch. 1973. The binding properties of anti-phosphorylcholine mouse myeloma proteins as measured by protein fluorescence. J. Biol. Chem. 248:5443-5447.
40. Pottumarthy, S., V. C. Wells, and A. J. Morris. 2000. A comparison of seven tests for serological diagnosis of tuberculosis. J. Clin. Microbiol. 38:2227-2231.
41. Quesniaux, V. J., D. M. Nicolle, D. Torres, L. Kremer, Y. Guerardel, J. Nigou, G. Puzo, F. Erard, and B. Rifle. 2004. Toll-like receptor 2 (TLR2)-dependent-positive and TLR2-independent-negative regulation of proinflammatory cytokines by mycobacterial lipomannans. J. Immunol. 172:4425-4434.
42. Raez, L. E., S. Fein, and E. R. Podack. 2005. Lung cancer immunotherapy. Clin. Med. Res. 3:221-228.
43. Raja, A., K. R. Uma Devi, B. Ramalingam, and P. J. Brennan. 2002. Immunoglobulin G, A, and M responses in serum and circulating immune complexes elicited by the 16-kilodalton antigen of Mycobacterium tuberculosis. Clin. Diagn. Lab. Immunol. 9:308-312.
44. Rosseels, V., S. Marche, V. Roupie, M. Govaerts, J. Godfroid, K. Walravens, and K. Huygen. 2006. Members of the 30- to 32-kilodalton mycolyl transferase family (Ag85) from culture filtrate of Mycobacterium avium subsp. paratuberculosis are immunodominant Th1-type antigens recognized early upon infection in mice and cattle. Infect. Immun. 74:202-212.
45. Saha, A., A. Sharma, A. Dhar, B. Bhattacharyya, S. Roy, and S. K. Das Gupta. 2005. Antagonists of Hsp16.3, a low-molecular-weight mycobacterial chaperone and virulence factor, derived from phage-displayed peptide libraries. Appl. Environ. Microbiol. 71:7334-7344.
46. Scala, G., X. Chen, W. Liu, J. N. Telles, O. J. Cohen, M. Vaccarezza, T. Igarashi, and A. S. Fauci. 1999. Selection of HIV-specific immunogenic epitopes by screening random peptide libraries with HIV-1-positive sera. J. Immunol. 162:6155-6161.
47. Scarpellini, P., S. Tasca, L. Galli, A. Beretta, A. Lazzarin, and C. Fortis. 2004. Selected pool of peptides from ESAT-6 and CFP-10 proteins for detection of Mycobacterium tuberculosis infection. J. Clin. Microbiol. 42: 3469-3474.
48. Schluger, N. W., and W. N. Rom. 1998. The host immune response to tuberculosis. Am. J. Respir. Crit. Care Med. 157:679-691.
49. Skjot, R. L., T. Oettinger, I. Rosenkrands, P. Ravn, I. Brock, S. Jacobsen, and P. Andersen. 2000. Comparative evaluation of low-molecular-mass proteins from Mycobacterium tuberculosis identifies members of the ESAT-6 family as immunodominant T-cell antigens. Infect. Immun. 68:214-220.
50. Smith, G. P., and V. A. Petrenko. 1997. Phage display. Chem. Rev. 97:391-410.
51. Stanford, J., C. Stanford, and J. Grange. 2004. Immunotherapy with Mycobacterium vaccae in the treatment of tuberculosis. Front. Biosci. 9:1701-1719.
52. Steinhauer, C., C. Wingren, A. C. Hager, and C. A. Borrebaeck. 2002. Single framework recombinant antibody fragments designed for protein chip applications. BioTechniques Suppl. 2002:38-45.
53. Strohmeier, G. R., and M. J. Fenton. 1999. Roles of lipoarabinomannan in the pathogenesis of tuberculosis. Microbes Infect. 1:709-717.
54. Tessema, T. A., G. Bjune, B. Hamasur, S. Svenson, H. Syre, and B. Bjorvatn. 2002. Circulating antibodies to lipoarabinomannan in relation to sputum microscopy, clinical features and urinary anti-lipoarabinomannan detection in pulmonary tuberculosis. Scand. J. Infect. Dis. 34:97-103.
55. Tishler, M., and Y. Shoenfeld. 2006. BCG immunotherapy-from pathophysiology to clinical practice. Expert Opin. Drug Safety 5:225-229.
56. Vyas, N. K., M. N. Vyas, M. C. Chervenak, D. R. Bundle, B. M. Pinto, and F. A. Quiocho. 2003. Structural basis of peptide-carbohydrate mimicry in an antibody-combining site. Proc. Natl. Acad. Sci. USA 100:15023-15028.
57. Waldmann, T. A. 2006. Effective cancer therapy through immunomodulation. Annu. Rev. Med. 57:65-81.
58. Wilkinson, R. J., K. Haslov, R. Rappuoli, F. Giovannoni, P. R. Narayanan, C. R. Desai, H. M. Vordermeier, J. Paulsen, G. Pasvol, J. Ivanyi, and M. Singh. 1997. Evaluation of the recombinant 38-kilodalton antigen of Mycobacterium tuberculosis as a potential immunodiagnostic reagent. J. Clin. Microbiol. 35:553-557.
59. World Health Organization. 2005. Tuberculosis. Fact sheet no. 104. World Health Organization, Geneva, Switzerland. [Online.] http://www.who.org.
60. Yoshida, A., and Y. Koide. 1997. Arabinofuranosyl-terminated and mannosylated lipoarabinomannans from Mycobacterium tuberculosis induce different levels of interleukin-12 expression in murine macrophages. Infect. Immun. 65:1953-1955.