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Volumn 8, Issue 21, 2006, Pages 4783-4786

Synthesis of 3-(Aryl)alkenyl-β-lactams by an efficient application of olefin cross-metathesis on solid support

Author keywords

[No Author keywords available]

Indexed keywords

ALKENE; BETA LACTAM; HYPOCHOLESTEROLEMIC AGENT;

EID: 33750313193     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol061786u     Document Type: Article
Times cited : (51)

References (32)
  • 12
    • 3042621839 scopus 로고    scopus 로고
    • and references therein
    • Burnett, D. A. Curr. Med. Chem. 2004, 11, 1873 and references therein.
    • (2004) Curr. Med. Chem. , vol.11 , pp. 1873
    • Burnett, D.A.1
  • 24
    • 0034686858 scopus 로고    scopus 로고
    • See
    • The effect of N-aryl-substituted imines on the stereochemistry of the resulting β-lactam ring has been already observed in the homogeneous phase. See: Banik, B. K.; Becker, F. F. Tetrahedron Lett. 2000, 41, 6551.
    • (2000) Tetrahedron Lett. , vol.41 , pp. 6551
    • Banik, B.K.1    Becker, F.F.2
  • 26
    • 0029903708 scopus 로고    scopus 로고
    • See
    • Strict exclusion of moisture and air was required in previous reports on cross-metathesis of polymer-supported olefins under first-generation Grubbs catalyst. See: (a) Schuster, M.; Pernerstorfer, J.; Blechert, S. Angew. Chem., Int. Ed. 1996, 35, 1979.
    • (1996) Angew. Chem., Int. Ed. , vol.35 , pp. 1979
    • Schuster, M.1    Pernerstorfer, J.2    Blechert, S.3
  • 28
    • 33750301783 scopus 로고    scopus 로고
    • note
    • 2 for 1 h. The mixture was filtered, and the filtrate was evaporated under reduced pressure. Finally, the crude material was purified by column chromatography.
  • 29
    • 33746114221 scopus 로고    scopus 로고
    • and references therein
    • For different attempts to avoid contamination of products with ruthenium, see: McEleney, K.; Allen, D. P.; Holliday, A. E.; Crudden, C. M. Org. Lett. 2006, 8, 2663 and references therein.
    • (2006) Org. Lett. , vol.8 , pp. 2663
    • McEleney, K.1    Allen, D.P.2    Holliday, A.E.3    Crudden, C.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.