-
1
-
-
0000947117
-
Clinical manifestations of acute myeloid leukemia
-
Edited by Hoffman R, Benz EJ Jr, Shattil SJ, et al. New York: Churchill Livingstone
-
Miller K, Daoust P: Clinical manifestations of acute myeloid leukemia. In Hematology: Basic Principles and Practice, edn 3. Edited by Hoffman R, Benz EJ Jr, Shattil SJ, et al. New York: Churchill Livingstone, 2000: 2017-2018.
-
(2000)
Hematology: Basic Principles and Practice, Edn 3
, pp. 2017-2018
-
-
Miller, K.1
Daoust, P.2
-
2
-
-
0036328950
-
Usefulness of anti-CD117 in the flow cytometric analysis of acute leukemia
-
Hans CP, Finn WG, Singleton TP, et al.: Usefulness of anti-CD117 in the flow cytometric analysis of acute leukemia. Am J Clin Pathol 2002, 117:301-305.
-
(2002)
Am J Clin Pathol
, vol.117
, pp. 301-305
-
-
Hans, C.P.1
Finn, W.G.2
Singleton, T.P.3
-
3
-
-
79960971089
-
The amount of c-kit receptor tyrosine kinase predicts outcome in acute myelogenous leukemia
-
Abstract 2992
-
Del Poeta G, Venditti A, Maurillo L, et al.: The amount of c-kit receptor tyrosine kinase predicts outcome in acute myelogenous leukemia. Blood (ASH Annual Meeting Abstracts) 2001, 98:716a (Abstract 2992).
-
(2001)
Blood (ASH Annual Meeting Abstracts)
, vol.98
-
-
Del Poeta, G.1
Venditti, A.2
Maurillo, L.3
-
4
-
-
0031840621
-
Serum soluble c-kit receptor and expression of c-kit protein and mRNA in acute myeloid leukemia
-
Tajima F, Kawatani T, Ishiga K, et al.: Serum soluble c-kit receptor and expression of c-kit protein and mRNA in acute myeloid leukemia. Eur J Haematol 1998, 60:289-296.
-
(1998)
Eur J Haematol
, vol.60
, pp. 289-296
-
-
Tajima, F.1
Kawatani, T.2
Ishiga, K.3
-
5
-
-
2742529418
-
Human proto-oncogene c-kit: A new cell surface receptor tyrosine kinase for an unidentified ligand
-
Yarden Y, Kuang WI, Yang-Feng T, et al.: Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand. Embo J 1987, 6:3341-3351.
-
(1987)
Embo J
, vol.6
, pp. 3341-3351
-
-
Yarden, Y.1
Kuang, W.I.2
Yang-Feng, T.3
-
6
-
-
0025001894
-
Stem cell factor is encoded at the Sl locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor
-
Zsebo KM, Williams DA, Geissler EN, et al.: Stem cell factor is encoded at the Sl locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor. Cell 1990, 63:213-224.
-
(1990)
Cell
, vol.63
, pp. 213-224
-
-
Zsebo, K.M.1
Williams, D.A.2
Geissler, E.N.3
-
7
-
-
0026066984
-
A specific combination of substrates is involved in signal transduction by the kit-encoded receptor
-
Lev S, Givol D, Yarden Y: A specific combination of substrates is involved in signal transduction by the kit-encoded receptor. Embo J 1991, 10:647-654.
-
(1991)
Embo J
, vol.10
, pp. 647-654
-
-
Lev, S.1
Givol, D.2
Yarden, Y.3
-
8
-
-
0028181438
-
Expression of the Kit and KitA receptor isoforms in human acute myelogenous leukemia
-
Piao X, Curtis JE, Minkin S, et al.: Expression of the Kit and KitA receptor isoforms in human acute myelogenous leukemia. Blood 1994, 83:476-481.
-
(1994)
Blood
, vol.83
, pp. 476-481
-
-
Piao, X.1
Curtis, J.E.2
Minkin, S.3
-
9
-
-
0025765803
-
SH2 and SH3 domains: Elements that control interactions of cytoplasmic signaling proteins
-
Koch CA, Anderson D, Moran MF, et al.: SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins. Science 1991, 252:668-674.
-
(1991)
Science
, vol.252
, pp. 668-674
-
-
Koch, C.A.1
Anderson, D.2
Moran, M.F.3
-
10
-
-
0037606031
-
Sustained complete hematologic remission after administration of the tyrosine kinase inhibitor imatinib mesylate in a patient with refractory, secondary AML
-
Kindler T, Breitenbuecher F, Marx A, et al.: Sustained complete hematologic remission after administration of the tyrosine kinase inhibitor imatinib mesylate in a patient with refractory, secondary AML. Blood 2003, 101:2960-2962.
-
(2003)
Blood
, vol.101
, pp. 2960-2962
-
-
Kindler, T.1
Breitenbuecher, F.2
Marx, A.3
-
11
-
-
0032828882
-
Early signaling pathways activated by c-Kit in hematopoietic progenitor cells
-
Linnekin D: Early signaling pathways activated by c-Kit in hematopoietic progenitor cells. Int J Biochem Cell Biol 1999, 31:1053-1074.
-
(1999)
Int J Biochem Cell Biol
, vol.31
, pp. 1053-1074
-
-
Linnekin, D.1
-
12
-
-
0027791360
-
Changes in phenotype and proliferative potential of human acute myeloblastic leukemia cells in culture with stem cell factor
-
Ikeda H, Kanakura Y, Furitsu T, et al.: Changes in phenotype and proliferative potential of human acute myeloblastic leukemia cells in culture with stem cell factor. Exp Hematol 1993, 21:1686-1694.
-
(1993)
Exp Hematol
, vol.21
, pp. 1686-1694
-
-
Ikeda, H.1
Kanakura, Y.2
Furitsu, T.3
-
13
-
-
0034684662
-
Hematopoietic stem cells need two signals to prevent apoptosis; BCL-2 can provide one of these, KitI/c-Kit signaling the other
-
Domen J, Weissman IL: Hematopoietic stem cells need two signals to prevent apoptosis; BCL-2 can provide one of these, KitI/c-Kit signaling the other. J Exp Med 2000, 192:1707-1718.
-
(2000)
J Exp Med
, vol.192
, pp. 1707-1718
-
-
Domen, J.1
Weissman, I.L.2
-
14
-
-
0026775925
-
Effects of human stem cell factor (c-kit ligand) on proliferation of myeloid leukemia cells: Heterogeneity in response and synergy with other hematopoietic growth factors
-
Pietsch T, Kyas U, Steffens U, et al.: Effects of human stem cell factor (c-kit ligand) on proliferation of myeloid leukemia cells: heterogeneity in response and synergy with other hematopoietic growth factors. Blood 1992, 80:1199-1206.
-
(1992)
Blood
, vol.80
, pp. 1199-1206
-
-
Pietsch, T.1
Kyas, U.2
Steffens, U.3
-
15
-
-
0025718579
-
Expression and functional role of the proto-oncogene c-kit in acute myeloblastic leukemia cells
-
Ikeda H, Kanakura Y, Tamaki T, et al.: Expression and functional role of the proto-oncogene c-kit in acute myeloblastic leukemia cells. Blood 1991, 78:2962-2968.
-
(1991)
Blood
, vol.78
, pp. 2962-2968
-
-
Ikeda, H.1
Kanakura, Y.2
Tamaki, T.3
-
16
-
-
0031437680
-
Expression of the stem cell factor c-kit (CD117) in acute leukemias
-
Sperling C, Schwartz S, Buchner T, et al.: Expression of the stem cell factor c-kit (CD117) in acute leukemias. Haematologica 1997, 82:617-621.
-
(1997)
Haematologica
, vol.82
, pp. 617-621
-
-
Sperling, C.1
Schwartz, S.2
Buchner, T.3
-
17
-
-
0032996540
-
Expression of the c-kit receptor (CD117) is a feature of almost all subtypes of de novo acute myeloblastic leukemia (AML), including cytogenetically good-risk AML, and lacks prognostic significance
-
Schwartz S, Heinecke A, Zimmerman M, et al.: Expression of the c-kit receptor (CD117) is a feature of almost all subtypes of de novo acute myeloblastic leukemia (AML), including cytogenetically good-risk AML, and lacks prognostic significance. Leuk Lymphoma 1999, 34:85-94.
-
(1999)
Leuk Lymphoma
, vol.34
, pp. 85-94
-
-
Schwartz, S.1
Heinecke, A.2
Zimmerman, M.3
-
18
-
-
0029046519
-
Soluble c-kit molecule in serum from healthy individuals and patients with haemopoietic disorders
-
Kawakita M, Yonemura Y, Miyake H, et al.: Soluble c-kit molecule in serum from healthy individuals and patients with haemopoietic disorders. Br J Haematol 1995, 91:23-29.
-
(1995)
Br J Haematol
, vol.91
, pp. 23-29
-
-
Kawakita, M.1
Yonemura, Y.2
Miyake, H.3
-
19
-
-
0024438920
-
The expression of the proto-oncogene C-kit in the blast cells of acute myeloblastic leukemia
-
Wang C, Curtis JE, Geissler EN, et al.: The expression of the proto-oncogene C-kit in the blast cells of acute myeloblastic leukemia. Leukemia 1989, 3:699-702.
-
(1989)
Leukemia
, vol.3
, pp. 699-702
-
-
Wang, C.1
Curtis, J.E.2
Geissler, E.N.3
-
20
-
-
0345707694
-
Lack of KIT or FMS internal tandem duplications but co-expression with ligands in AML
-
Zheng R, Klang K, Gorin N, et al.: Lack of KIT or FMS internal tandem duplications but co-expression with ligands in AML. Leuk Res 2004, 28:121-126. Discusses the importance of c-kit expression in AML.
-
(2004)
Leuk Res
, vol.28
, pp. 121-126
-
-
Zheng, R.1
Klang, K.2
Gorin, N.3
-
21
-
-
0030048429
-
Stem cell factor as a survival and growth factor in human normal and malignant hematopoiesis
-
Hassan H, Zander A: Stem cell factor as a survival and growth factor in human normal and malignant hematopoiesis. Acta Haematol 1996, 95:257-262.
-
(1996)
Acta Haematol
, vol.95
, pp. 257-262
-
-
Hassan, H.1
Zander, A.2
-
22
-
-
0031708688
-
Stem cell factor enhances the adhesion of AML cells to fibronectin and augments fibronectin-mediated anti-apoptotic and proliferative signals
-
Bendall L, Makrynikola V, Hutchinson A, et al.: Stem cell factor enhances the adhesion of AML cells to fibronectin and augments fibronectin-mediated anti-apoptotic and proliferative signals. Leukemia 1998, 12:1375-1382.
-
(1998)
Leukemia
, vol.12
, pp. 1375-1382
-
-
Bendall, L.1
Makrynikola, V.2
Hutchinson, A.3
-
23
-
-
0035881982
-
Implication of tyrosine kinase receptor and steel factor in cell density-dependent growth in cervical cancers and leukemias
-
Caceres-Cortes J, Alvarado-Moreno J, Waga K, et al.: Implication of tyrosine kinase receptor and steel factor in cell density-dependent growth in cervical cancers and leukemias. Cancer Res 2001, 61:6281-6289.
-
(2001)
Cancer Res
, vol.61
, pp. 6281-6289
-
-
Caceres-Cortes, J.1
Alvarado-Moreno, J.2
Waga, K.3
-
24
-
-
0027791309
-
Modulation of p145c-kit function in cells of patients with acute myeloblastic leukemia
-
Buhring H, Herbst R, Kostka G, et al.: Modulation of p145c-kit function in cells of patients with acute myeloblastic leukemia. Cancer Res 1993, 53:4424-4431.
-
(1993)
Cancer Res
, vol.53
, pp. 4424-4431
-
-
Buhring, H.1
Herbst, R.2
Kostka, G.3
-
25
-
-
0024208117
-
Expression of a 150-kD cell surface antigen identified by monoclonal antibody YB5.B8 is associated with poor prognosis in acute non-lymphoblastic leukaemia
-
Ashman L, Roberts M, Gadd S, et al.: Expression of a 150-kD cell surface antigen identified by monoclonal antibody YB5.B8 is associated with poor prognosis in acute non-lymphoblastic leukaemia. Leuk Res 1988, 12:923-928.
-
(1988)
Leuk Res
, vol.12
, pp. 923-928
-
-
Ashman, L.1
Roberts, M.2
Gadd, S.3
-
26
-
-
0025780864
-
Monoclonal antibody YB5.B8 identifies the human c-kit protein product
-
Lerner NB, Nocka KH, Cole SR, et al.: Monoclonal antibody YB5.B8 identifies the human c-kit protein product. Blood 1991, 77:1876-1883.
-
(1991)
Blood
, vol.77
, pp. 1876-1883
-
-
Lerner, N.B.1
Nocka, K.H.2
Cole, S.R.3
-
27
-
-
0030657009
-
Expression of c-kit and functional drug efflux are correlated in de novo acute myeloid leukaemia
-
Sincock P, Ashman L: Expression of c-kit and functional drug efflux are correlated in de novo acute myeloid leukaemia. Leukemia 1997, 11:1850-1857.
-
(1997)
Leukemia
, vol.11
, pp. 1850-1857
-
-
Sincock, P.1
Ashman, L.2
-
28
-
-
0037443479
-
Amount of spontaneous apoptosis detected by Bax/Bcl-2 ratio predicts outcome in acute myeloid leukemia (AML)
-
Del Poeta G, Venditti A, Del Principe MI, et al.: Amount of spontaneous apoptosis detected by Bax/Bcl-2 ratio predicts outcome in acute myeloid leukemia (AML). Blood 2003, 101:2125-2131. Discusses the importance of apoptotic markers and prognosis in AML.
-
(2003)
Blood
, vol.101
, pp. 2125-2131
-
-
Del Poeta, G.1
Venditti, A.2
Del Principe, M.I.3
-
29
-
-
0028041311
-
The c-kit ligand suppresses apoptosis of human natural killer cells through the upregulation of bcl-2
-
Carson WE, Haldar S, Baiocchi RA, et al.: The c-kit ligand suppresses apoptosis of human natural killer cells through the upregulation of bcl-2. Proc Natl Acad Sci U S A 1994, 91:7553-7557.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 7553-7557
-
-
Carson, W.E.1
Haldar, S.2
Baiocchi, R.A.3
-
30
-
-
0028040783
-
Prognostic value of immunophenotyping in acute myeloid leukemia
-
Bradstock K, Matthews J, Benson E, et al.: Prognostic value of immunophenotyping in acute myeloid leukemia. Blood 1994, 84:1220-1225.
-
(1994)
Blood
, vol.84
, pp. 1220-1225
-
-
Bradstock, K.1
Matthews, J.2
Benson, E.3
-
31
-
-
10744227578
-
C-kit receptor expression in acute leukemias-association with patient and disease characteristics and with outcome
-
Tsao A, Kantarjian H, Thomas D, et al.: C-kit receptor expression in acute leukemias-association with patient and disease characteristics and with outcome. Leuk Res 2004, 28:373-378.
-
(2004)
Leuk Res
, vol.28
, pp. 373-378
-
-
Tsao, A.1
Kantarjian, H.2
Thomas, D.3
-
32
-
-
33750375324
-
CD117 expression is a poor prognostic factor for progression free survival and freedom from progression in patients with newly diagnosed acute myelogenous leukemia
-
[abstract]: (Abstract 3292)
-
Saber W, Abou-Jawde R, Hsi E, et al.: CD117 expression is a poor prognostic factor for progression free survival and freedom from progression in patients with newly diagnosed acute myelogenous leukemia [abstract]. Blood (ASH Annual Meeting Abstracts) 2005, 106:921a (Abstract 3292).
-
(2005)
Blood (ASH Annual Meeting Abstracts)
, vol.106
-
-
Saber, W.1
Abou-Jawde, R.2
Hsi, E.3
-
33
-
-
0035679772
-
Effects of signal transduction inhibitor 571 in acute myelogenous leukemia cells
-
Scappini B, Onida F, Kantarjian H, et al.: Effects of signal transduction inhibitor 571 in acute myelogenous leukemia cells. Clin Cancer Res 2001, 7:3884-3893.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3884-3893
-
-
Scappini, B.1
Onida, F.2
Kantarjian, H.3
-
34
-
-
0034895284
-
Activating mutations of c-kit at codon 816 confer drug resistance in human leukemia cells
-
Ning Z, Li J, Arceci R: Activating mutations of c-kit at codon 816 confer drug resistance in human leukemia cells. Leak lymphoma 2001, 41:513-522.
-
(2001)
Leak Lymphoma
, vol.41
, pp. 513-522
-
-
Ning, Z.1
Li, J.2
Arceci, R.3
-
35
-
-
0037087531
-
Inhibition of KIT tyrosine kinase activity: A novel molecular approach to the treatment of KIT-positive malignancies
-
Heinrich MC, Blanke CD, Druker BJ, Corless CL: Inhibition of KIT tyrosine kinase activity: a novel molecular approach to the treatment of KIT-positive malignancies. J Clin Oncol 2002, 20:1692-1703. A review of the biology and clinical applications of the new c-kit inhibitors.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1692-1703
-
-
Heinrich, M.C.1
Blanke, C.D.2
Druker, B.J.3
Corless, C.L.4
-
36
-
-
0035383812
-
Signal transducer and activator of transcription 3 activation is required for Asp(816) mutant c-kit-mediated cytokine-independent survival and proliferation in leukemia cells
-
Ning ZQ, Li J, Arceci RJ: Signal transducer and activator of transcription 3 activation is required for Asp(816) mutant c-kit-mediated cytokine-independent survival and proliferation in leukemia cells. Blood 2001, 97:3559-3567.
-
(2001)
Blood
, vol.97
, pp. 3559-3567
-
-
Ning, Z.Q.1
Li, J.2
Arceci, R.J.3
-
37
-
-
0036814971
-
Molecular genetics of human leukemias: New insights into therapy
-
review
-
Cilliland D: Molecular genetics of human leukemias: new insights into therapy [review]. Semin Hematol 2002, 39:6-11.
-
(2002)
Semin Hematol
, vol.39
, pp. 6-11
-
-
Cilliland, D.1
-
38
-
-
33747119609
-
Distinct characteristics of t(8;21) acute myeloid leukemia with active kit mutation
-
[abstract]: (Abstract 3297)
-
Lorenzo F, Nishii K, Monma F, et al.: Distinct characteristics of t(8;21) acute myeloid leukemia with active kit mutation [abstract]. Blood (ASH Annual Meeting Abstracts) 2005, 106:922a (Abstract 3297).
-
(2005)
Blood (ASH Annual Meeting Abstracts)
, vol.106
-
-
Lorenzo, F.1
Nishii, K.2
Monma, F.3
-
39
-
-
0032989226
-
C-kit proto-oncogene exon 8 in-frame deletion plus insertion mutations in acute myeloid leukemia
-
Gari M, Goodeve A, Wilson G, et al.: c-kit proto-oncogene exon 8 in-frame deletion plus insertion mutations in acute myeloid leukemia. Br J Haematol 1999, 105:894-900.
-
(1999)
Br J Haematol
, vol.105
, pp. 894-900
-
-
Gari, M.1
Goodeve, A.2
Wilson, G.3
-
40
-
-
0034993741
-
Classes of c-kit activating mutations: Proposed mechanisms of action and implications for disease classification and therapy
-
Longley B, Reguera M, Ma Y: Classes of c-kit activating mutations: proposed mechanisms of action and implications for disease classification and therapy. Leak Res 2001, 25:571-576.
-
(2001)
Leak Res
, vol.25
, pp. 571-576
-
-
Longley, B.1
Reguera, M.2
Ma, Y.3
-
41
-
-
0042967809
-
Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia
-
Lowenberg B, van Putten W, Theobald M, et al.: Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia. N Engl J Med 2003, 349:743-752.
-
(2003)
N Engl J Med
, vol.349
, pp. 743-752
-
-
Lowenberg, B.1
Van Putten, W.2
Theobald, M.3
-
42
-
-
0033816156
-
Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors
-
Buchdunger E, Cioffi C, Law N, et al.: Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors. J Pharmacol Exp Ther 2000, 295:139-145.
-
(2000)
J Pharmacol Exp Ther
, vol.295
, pp. 139-145
-
-
Buchdunger, E.1
Cioffi, C.2
Law, N.3
-
43
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker B, Tamura S, Buchdunger E, et al.: Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med 1996, 2:561-566.
-
(1996)
Nat Med
, vol.2
, pp. 561-566
-
-
Druker, B.1
Tamura, S.2
Buchdunger, E.3
-
44
-
-
10744229862
-
Results of imatinib mesylate therapy in patients with refractory or recurrent acute myeloid leukemia, high-risk myelodysplastic syndrome, and myeloproliferative disorders
-
Cortes J, Giles F, O'Brien S, et al.: Results of imatinib mesylate therapy in patients with refractory or recurrent acute myeloid leukemia, high-risk myelodysplastic syndrome, and myeloproliferative disorders. Cancer 2003, 97:2760-2766.
-
(2003)
Cancer
, vol.97
, pp. 2760-2766
-
-
Cortes, J.1
Giles, F.2
O'Brien, S.3
-
45
-
-
2342518106
-
Efficacy and safety of imatinib in adult patients with c-kit-positive acute myeloid leukemia
-
Kindler T, Breitenbuecher F, Marx A, et al.: Efficacy and safety of imatinib in adult patients with c-kit-positive acute myeloid leukemia. Blood 2004, 103:3644-3654. Discusses the biology and clinical results of using imatinib in patients with AML.
-
(2004)
Blood
, vol.103
, pp. 3644-3654
-
-
Kindler, T.1
Breitenbuecher, F.2
Marx, A.3
-
46
-
-
0033619144
-
Isoforms of c-kit differ in activation of signaling pathways and transformation of NIH3T3 fibroblasts
-
Caruana G, Cambareri A, Ashman L: Isoforms of c-kit differ in activation of signaling pathways and transformation of NIH3T3 fibroblasts. Oncogene 1999, 18:5573-5581.
-
(1999)
Oncogene
, vol.18
, pp. 5573-5581
-
-
Caruana, G.1
Cambareri, A.2
Ashman, L.3
-
47
-
-
0034665903
-
CGP57148B (STI-571) induces differentiation and apoptosis and sensitizes Bcr-Abl-positive leukemia cells to apoptosis due to antileukemic drugs
-
Fang G, Kim C, Perkins C, et al.: CGP57148B (STI-571) induces differentiation and apoptosis and sensitizes Bcr-Abl-positive leukemia cells to apoptosis due to antileukemic drugs. Blood 2000, 96:2246-2253.
-
(2000)
Blood
, vol.96
, pp. 2246-2253
-
-
Fang, G.1
Kim, C.2
Perkins, C.3
-
48
-
-
40749153231
-
Results of a multicenter phase II trial for older patients with c-kit positive acute myeloid leukemia and high-risk myelodysplastic syndrome using low-dose Ara-C and imatinib
-
[abstract]: (Abstract 1853)
-
Heidel F, Cortes J, Ruecker F, et al.: Results of a multicenter phase II trial for older patients with c-kit positive acute myeloid leukemia and high-risk myelodysplastic syndrome using low-dose Ara-C and imatinib [abstract]. Blood (ASH Annual Meeting Abstracts) 2005, 106:527a (Abstract 1853).
-
(2005)
Blood (ASH Annual Meeting Abstracts)
, vol.106
-
-
Heidel, F.1
Cortes, J.2
Ruecker, F.3
-
49
-
-
0036325621
-
The protein tyrosine kinase inhibitor SU5614 inhibits VEGF-induced endothelial cell sprouting and induces growth arrest and apoptosis by inhibition of c-kit in AML cells
-
Spiekermann K, Farber F, Voswinckel R, et al.: The protein tyrosine kinase inhibitor SU5614 inhibits VEGF-induced endothelial cell sprouting and induces growth arrest and apoptosis by inhibition of c-kit in AML cells. Exp Hematol 2002, 30:767-773.
-
(2002)
Exp Hematol
, vol.30
, pp. 767-773
-
-
Spiekermann, K.1
Farber, F.2
Voswinckel, R.3
-
50
-
-
0035282940
-
The antiangiogenic protein kinase inhibitors SU5416 and SU6668 inhibit the SCF receptor (c-kit) in a human myeloid leukemia cell line and in acute myeloid leukemic blasts
-
Smolich BD, Yuen HA, West KA, et al.: The antiangiogenic protein kinase inhibitors SU5416 and SU6668 inhibit the SCF receptor (c-kit) in a human myeloid leukemia cell line and in acute myeloid leukemic blasts. Blood 2001, 97:1413-1421.
-
(2001)
Blood
, vol.97
, pp. 1413-1421
-
-
Smolich, B.D.1
Yuen, H.A.2
West, K.A.3
-
51
-
-
0043245991
-
SU5416, a small molecule tyrosine kinase receptor inhibitor, has biologic activity in patients with refractory acute myeloid leukemia or myelodysplastic syndromes
-
Giles F, Stopeck A, Silverman L, et al.: SU5416, a small molecule tyrosine kinase receptor inhibitor, has biologic activity in patients with refractory acute myeloid leukemia or myelodysplastic syndromes. Blood 2003, 102:795-801.
-
(2003)
Blood
, vol.102
, pp. 795-801
-
-
Giles, F.1
Stopeck, A.2
Silverman, L.3
-
52
-
-
0141993064
-
A phase II clinical study of SU5417 in patients with refractory acute myeloid leukemia
-
Fiedler W, Mesters R, Tinnefeld H, et al.: A phase II clinical study of SU5417 in patients with refractory acute myeloid leukemia. Blood 2003, 102:2763-2767.
-
(2003)
Blood
, vol.102
, pp. 2763-2767
-
-
Fiedler, W.1
Mesters, R.2
Tinnefeld, H.3
-
53
-
-
33750288714
-
PKC412 inhibits in vitro growth of neoplastic mast cells expressing the D816V-mutated variant of KIT: Comparison with AMN107 and imatinib, and evaluations of drug interactions
-
[abstract]: (Abstract 3523)
-
Gleixner KV, Mayerhofer M, Aichberger KJ, et al.: PKC412 inhibits in vitro growth of neoplastic mast cells expressing the D816V-mutated variant of KIT: comparison with AMN107 and imatinib, and evaluations of drug interactions [abstract]. Blood (ASH Annual Meeting Abstracts) 2005, 106:983a (Abstract 3523).
-
(2005)
Blood (ASH Annual Meeting Abstracts)
, vol.106
-
-
Gleixner, K.V.1
Mayerhofer, M.2
Aichberger, K.J.3
-
54
-
-
33745193452
-
Dasatinib (BMS-354825), a multi-targeted kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane and activation loop mutant KIT isoforms associated with human malignancies
-
[abstract]: (Abstract 3358)
-
Schittenhelm MM, Shiraga S, Schroeder A, et al.: Dasatinib (BMS-354825), a multi-targeted kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane and activation loop mutant KIT isoforms associated with human malignancies [abstract]. Blood (ASH Annual Meeting Abstracts) 2005, 106:938a (Abstract 3358).
-
(2005)
Blood (ASH Annual Meeting Abstracts)
, vol.106
-
-
Schittenhelm, M.M.1
Shiraga, S.2
Schroeder, A.3
-
55
-
-
33750348247
-
The multi-targeted receptor tyrosine kinase inhibitor, ABT-869, induces apoptosis of AML cells both in vitro and in vivo
-
Abstract 616
-
Shankar DB, Chang JC, Parcells B, et al.: The multi-targeted receptor tyrosine kinase inhibitor, ABT-869, induces apoptosis of AML cells both in vitro and in vivo. Blood (ASH Annual Meeting Abstracts) 2005, 106:183a (Abstract 616).
-
(2005)
Blood (ASH Annual Meeting Abstracts)
, vol.106
-
-
Shankar, D.B.1
Chang, J.C.2
Parcells, B.3
|