SCOPUS 정보 검색 플랫폼

Pharmacokinetic Profiling in Drug Research

Volumn , Issue , 2007, Pages 395-415

The bioprint ® Approach for the Evaluation of ADMET Properties: Application to the Prediction of Cytochrome P450 2D6 Inhibition

(4) Gozalbes, Rafael a Barbosa, Frédérique a Froloff, Nicolas a Horvath, Dragos a,b

a CEREP (France)

b INSTITUT PASTEUR DE LILLE (France)

Author keywords

ADMET properties; BioPrint approach; Computational strategies; Cytochrome P450 2D6 inhibition; Potency, safety, good pharmacokinetic (PK) properties

Indexed keywords

ADMET PROPERTIES; COMPUTATIONAL STRATEGY; CYTOCHROME P450; POTENCY, SAFETY, GOOD PHARMACOKINETIC (PK) PROPERTIES;

EID: 33750304266 PISSN: None EISSN: None Source Type: Book
DOI: 10.1002/9783906390468.ch23 Document Type: Chapter

Times cited : (2)

References (38)

1
- 0023947965
- R. A. Prentis, Y. Lis, S. R.Walker, Br. J. Clin. Pharmacol. 1998, 25, 387.
- (1998) Br. J. Clin. Pharmacol , vol.25 , pp. 387
- Prentis, R.A.¹ Lis, Y.² Walker, S.R.³

2
- 0036234783
- H. van de Waterbeemd, Curr. Opin. Drug Disc. Dev. 2002, 5, 33.
- (2002) Curr. Opin. Drug Disc. Dev , vol.5 , pp. 33
- van de Waterbeemd, H.¹

3
- 0031178199
- G.W. Milne, J. Chem. Inf. Comput. Sci. 1997, 37, 639.
- (1997) J. Chem. Inf. Comput. Sci , vol.37 , pp. 639
- Milne, G.W.¹

4
- 84956609937
- R. Todeschini, V. Consonni,Wiley-VCH, Weinheim,
- HHandbook of Molecular DescriptorsI, Eds. R. Todeschini, V. Consonni,Wiley-VCH, Weinheim, 2003.
- (2003)

5
- 0034625096
- G. Cruciani, P. Crivori, P. A. Carrupt, B. Testa, THEOCHEM 2000, 503, 17.
- (2000) THEOCHEM , vol.503 , pp. 17
- Cruciani, G.¹ Crivori, P.² Carrupt, P.A.³ Testa, B.⁴

6
- 0028534521
- G. Klopman, M. Dimayuga, J. Talafous, J. Chem. Inf. Comput. Sci. 1994, 34, 1320.
- (1994) J. Chem. Inf. Comput. Sci , vol.34 , pp. 1320
- Klopman, G.¹ Dimayuga, M.² Talafous, J.³

7
- 0037204551
- J. Langowski, A. Long, Adv. Drug Delivery Rev. 2002, 54, 407.
- (2002) Adv. Drug Delivery Rev , vol.54 , pp. 407
- Langowski, J.¹ Long, A.²

8
- 0036606241
- D. Butina, M. D. Segall, K. Frankcombe, Drug Disc. Today 2002, 7, S83.
- (2002) Drug Disc. Today , vol.7 , pp. S83
- Butina, D.¹ Segall, M.D.² Frankcombe, K.³

9
- 9044254525
- D. R. Nelson, L. Koymans, T. Kamataki, J. J. Stegeman, R. Feyereisen,D. J.Waxman, M. R. Waterman, O. Gotoh, M. J. Coon, R. W. Estabrook, I. C. Gunsalus, D.W. Nebert, Pharmacogenetics 1996, 6, 1.
- (1996) Pharmacogenetics , vol.6 , pp. 1
- Nelson, D.R.¹ Koymans, L.² Kamataki, T.³ Stegeman, J.J.⁴ Feyereisen, R.⁵ Waxman, D.J.⁶ Waterman, M.R.⁷ Gotoh, O.⁸ Coon, M.J.⁹ Estabrook, R.W.¹⁰ Gunsalus, I.C.¹¹ Nebert, D.W.¹²

10
- 0026496950
- S. Cholerton, A. K. Daly, J. R. Idle, Trends Pharmacol. Sci. 1992, 13, 434.
- (1992) Trends Pharmacol. Sci , vol.13 , pp. 434
- Cholerton, S.¹ Daly, A.K.² Idle, J.R.³

11
- 0037204550
- S. B. Kirton, C. A. Baxter, M. J. Sutcliffe, Adv. Drug Delivery Rev. 2002, 4, 385.
- (2002) Adv. Drug Delivery Rev , vol.4 , pp. 385
- Kirton, S.B.¹ Baxter, C.A.² Sutcliffe, M.J.³

12
- 0030914738
- D. F. Lewis, P. J. Eddershaw, P. S. Goldfarb, M. H. Tarbit, Xenobiotica 1997, 27, 319.
- (1997) Xenobiotica , vol.27 , pp. 319
- Lewis, D.F.¹ Eddershaw, P.J.² Goldfarb, P.S.³ Tarbit, M.H.⁴

13
- 0031934315
- D. F. Lewis, M. Dickins, R. J. Weaver, P. J. Eddershaw, P. S. Goldfarb, M. H. Tarbit, Xenobiotica 1998, 28, 235.
- (1998) Xenobiotica , vol.28 , pp. 235
- Lewis, D.F.¹ Dickins, M.² Weaver, R.J.³ Eddershaw, P.J.⁴ Goldfarb, P.S.⁵ Tarbit, M.H.⁶

14
- 0031133347
- G. D. Szklarz, J. R. Halpert, J. Comput.-Aided Mol. Des. 1997, 11, 265.
- (1997) J. Comput.-Aided Mol. Des , vol.11 , pp. 265
- Szklarz, G.D.¹ Halpert, J.R.²

15
- 0037145065
- D. F. Lewis, J. Inorg. Biochem. 2002, 91, 502.
- (2002) J. Inorg. Biochem , vol.91 , pp. 502
- Lewis, D.F.¹

16
- 84956624288
- L.Wes, BioCentury 2001, 9, A11.
- (2001) BioCentury , vol.9 , pp. A11
- Wes, L.¹

17
- 0002820079
- H. Jhoti, P.Williams, A.Ward, J. Cosme, Drug Metab. Rev. 2002, 34, 10.
- (2002) Drug Metab. Rev , vol.34 , pp. 10
- Jhoti, H.¹ Williams, P.² Ward, A.³ Cosme, J.⁴

18
- 0034970578
- T. L. Domanski, J. R. Halpert, Curr. Drug Metab. 2001, 2, 117.
- (2001) Curr. Drug Metab , vol.2 , pp. 117
- Domanski, T.L.¹ Halpert, J.R.²

19
- 0034962557
- S. Ekins, M. J. de Groot, J. P. Jones, Drug Metab. Dispos. 2001, 29, 936.
- (2001) Drug Metab. Dispos , vol.29 , pp. 936
- Ekins, S.¹ de Groot, M.J.² Jones, J.P.³

20
- 0033529017
- M. J. de Groot, M. J. Ackland, V. A. Home, A. A. Alex, B. C. Jones, J. Med. Chem. 1999, 42, 1515.
- (1999) J. Med. Chem , vol.42 , pp. 1515
- de Groot, M.J.¹ Ackland, M.J.² Home, V.A.³ Alex, A.A.⁴ Jones, B.C.⁵

21
- 0842304425
- L. Afzelius, I. Zamora, C. M. Masimirembwa, A. Karlen, T. B. Andersson, S. Mecucci, M. Baroni, G. Cruciani, J. Med. Chem. 2004, 47, 907.
- (2004) J. Med. Chem , vol.47 , pp. 907
- Afzelius, L.¹ Zamora, I.² Masimirembwa, C.M.³ Karlen, A.⁴ Andersson, T.B.⁵ Mecucci, S.⁶ Baroni, M.⁷ Cruciani, G.⁸

22
- 0038440502
- I. Zamora, L. Afzelius, G. Cruciani, J. Med. Chem. 2003, 46, 2313.
- (2003) J. Med. Chem , vol.46 , pp. 2313
- Zamora, I.¹ Afzelius, L.² Cruciani, G.³

23
- 0031405918
- M. D. Segall, M. C. Payne, S.W. Ellis, G. T. Tucker, R. N. Boyes, Eur. J. Drug Metab. Pharmacokinet. 1997, 22, 283.
- (1997) Eur. J. Drug Metab. Pharmacokinet , vol.22 , pp. 283
- Segall, M.D.¹ Payne, M.C.² Ellis, S.W.³ Tucker, G.T.⁴ Boyes, R.N.⁵

24
- 0036136527
- J. P. Jones, M. Mysinger, K. R. Korzekwa, Drug Metab. Dispos. 2002, 30, 7.
- (2002) Drug Metab. Dispos , vol.30 , pp. 7
- Jones, J.P.¹ Mysinger, M.² Korzekwa, K.R.³

25
- 0032902224
- C. L. Crespi, Curr. Opin. Drug Disc. Dev. 1999, 2, 15.
- (1999) Curr. Opin. Drug Disc. Dev , vol.2 , pp. 15
- Crespi, C.L.¹

26
- 0032997374
- P. J. Eddershaw, M. Dickins, Pharm. Sci. Technol. Today 1999, 2, 13.
- (1999) Pharm. Sci. Technol. Today , vol.2 , pp. 13
- Eddershaw, P.J.¹ Dickins, M.²

27
- 0034460075
- J. Pharmacol. Toxicol. Methods
- C. L. Crespi, D. M. Stresser, J. Pharmacol. Toxicol. Methods 2000, 44, 325.
- (2000) , vol.44 , pp. 325
- Crespi, C.L.¹ Stresser, D.M.²

28
- 0035069388
- A. D. Rodrigues, G. A. Winchell, M. R. Dobrinska, J. Clin. Pharmacol. 2001, 41, 368.
- (2001) J. Clin. Pharmacol , vol.41 , pp. 368
- Rodrigues, A.D.¹ Winchell, G.A.² Dobrinska, M.R.³

29
- 0043031339
- C. M. Krejsa, D. Horvath, S. L. Rogalski, J. E. Penzotti, B. Mao, F. Barbosa, J. C. Migeon, Curr. Opin. Drug Disc. Dev. 2003, 6, 470.
- (2003) Curr. Opin. Drug Disc. Dev , vol.6 , pp. 470
- Krejsa, C.M.¹ Horvath, D.² Rogalski, S.L.³ Penzotti, J.E.⁴ Mao, B.⁵ Barbosa, F.⁶ Migeon, J.C.⁷

30
- 0000353230
- D. J. Livingstone, J. Chem. Inf. Comput. Sci. 2000, 40, 195.
- (2000) J. Chem. Inf. Comput. Sci , vol.40 , pp. 195
- Livingstone, D.J.¹

31
- 0003399781
- HCombinatorial Library Design and Evaluation: Principles
- A. Ghose, V. Viswanadhan, Dekker, New York
- D. Horvath, in HCombinatorial Library Design and Evaluation: Principles, Software Tools and ApplicationsI, Eds. A. Ghose, V. Viswanadhan, Dekker, New York, 2001, p. 429 -472.
- (2001) Software Tools and ApplicationsI , pp. 429-472
- Horvath, D.¹

32
- 0030922822
- R. Todeschini, Anal. Chim. Acta 1997, 348, 419.
- (1997) Anal. Chim. Acta , vol.348 , pp. 419
- Todeschini, R.¹

33
- 0035003411
- A. Tropsha,W. Zheng, Curr. Pharm. Design 2001, 7, 599.
- (2001) Curr. Pharm. Design , vol.7 , pp. 599
- Tropsha, A.¹ Zheng, W.²

34
- 0037365125
- D. Horvath, C. Jeandenans, J. Chem. Inf. Comput. Sci. 2003, 43, 680.
- (2003) J. Chem. Inf. Comput. Sci , vol.43 , pp. 680
- Horvath, D.¹ Jeandenans, C.²

35
- 0037361990
- D. Horvath, C. Jeandenans, J. Chem. Inf. Comput. Sci. 2003, 43, 691.
- (2003) J. Chem. Inf. Comput. Sci , vol.43 , pp. 691
- Horvath, D.¹ Jeandenans, C.²

36
- 0021884394
- T. Wolff, L. M. Distelrath, M. T. Worthington, J. D. Groopman, G. J. Hammons, F. F. Kadlubar, R. A. Prough, M. V. Martin, F.P. Guengerich, Cancer Res. 1985, 45, 2116.
- (1985) Cancer Res , vol.45 , pp. 2116
- Wolff, T.¹ Distelrath, L.M.² Worthington, M.T.³ Groopman, J.D.⁴ Hammons, G.J.⁵ Kadlubar, F.F.⁶ Prough, R.A.⁷ Martin, M.V.⁸ Guengerich, F.P.⁹

37
- 0022899555
- U. A. Meyer, J. Gut, T. Kronbach, C. Skoda, U. T. Meier, T. Catin, Xenobiotica 1986, 16, 449.
- (1986) Xenobiotica , vol.16 , pp. 449
- Meyer, U.A.¹ Gut, J.² Kronbach, T.³ Skoda, C.⁴ Meier, U.T.⁵ Catin, T.⁶

38
- 0026046988
- S. A. Islam, C. R.Wolf,M. S. Lennard, J. E. Sternberg, Carcinogenesis 1991, 12, 2211.
- (1991) Carcinogenesis , vol.12 , pp. 2211
- Islam, S.A.¹ Wolf, C.R.² Lennard, M.S.³ Sternberg, J.E.⁴

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.