SCOPUS 정보 검색 플랫폼

Advanced Drug Delivery Reviews

Volumn 54, Issue 3, 2002, Pages 407-415

Computer systems for the prediction of xenobiotic metabolism

(2) Langowski, Jan a Long, Anthony a

a UNIVERSITY OF LEEDS (United Kingdom)

Author keywords

Camitro; COMPACT; Expert system; META; MetabolExpert; METEOR; QSAR

Indexed keywords

COMPUTER SYSTEMS; ENGINEERING RESEARCH; METABOLISM; TOXICITY;

THERAPEUTIC EFFICACY;

DRUG PRODUCTS;

XENOBIOTIC AGENT;

COMBINATORIAL CHEMISTRY; COMPUTER MODEL; COMPUTER SYSTEM; DATA BASE; DRUG DEVELOPMENT; DRUG EFFICACY; DRUG INDUSTRY; DRUG RESEARCH; DRUG SCREENING; DRUG SYNTHESIS; DRUG TOXICITY; MAMMAL; PREDICTION; PRIORITY JOURNAL; REVIEW; TECHNOLOGY; XENOBIOTIC METABOLISM;

EID: 0037204551 PISSN: 0169409X EISSN: None Source Type: Journal
DOI: 10.1016/S0169-409X(02)00011-X Document Type: Article

Times cited : (127)

References (31)

1
- 0027534457
- Quantitative structure-activity relationships of cytochrome P450
- (1993) Drug Metab. Rev. , vol.25 , pp. 1-48
- Hansch, C.¹ Zhang, L.²

2
- 0030873260
- Quantitative structure-activity relationships in substrates, inducers and inhibitors of cytochrome P4501 (CYP1)
- (1997) Drug Metab. Rev. , vol.29 , pp. 589-650
- Lewis, D.V.F.¹

3
- 0032536171
- Molecular modelling and quantitative structure-activity relationship studies on the interaction of omeprazole with cytochrome P450 isozymes
- (1998) Toxicology , vol.125 , pp. 31-44
- Lewis, D.V.F.¹ Lake, B.G.²

4
- 0034962557
- Pharmacophore and three-dimensional quantitative structure activity relationship methods for modelling cytochrome P450 active sites
- (2001) Drug Metab. Dispos. , vol.29 , pp. 936-944
- Ekins, S.¹ De Groot, M.J.² Jones, J.P.³

5
- 0035114457
- COMPACT: A structural approach to the modelling of cytochromes P450 and their interactions with xenobiotics
- (2001) J. Chem. Technol. Biotechnol. , vol.76 , pp. 237-244
- Lewis, D.V.F.¹

6
- 0031754690
- An improved and updated version of the compact procedure for the evaluation of P450-mediated activation
- (1998) Drug Metab. Rev. , vol.30 , pp. 709-737
- Lewis, D.V.F.¹ Ioannides, C.² Parke, D.V.³

7
- 0031932506
- Further evaluation of COMPACT, the molecular orbital approach for the prospective safety evaluation of chemicals
- (1998) Mutat. Res. , vol.412 , pp. 41-54
- Lewis, D.V.F.¹ Ioannides, C.² Parke, D.V.³

8
- 0028988098
- A retrospective evaluation of COMPACT predictions of the outcome of NTP rodent carcinogenicity testing
- (1995) Environ. Health Perspect. , vol.103 , pp. 178-184
- Lewis, D.V.F.¹ Ioannides, C.² Parke, D.V.³

9
- 0030924503
- Properties of cytochrome P450 isoenzymes and their substrates. I. Active site characteristics
- (1997) Drug Dev. Today , vol.2 , pp. 406-414
- Smith, D.A.¹ Ackland, M.J.² Jones, B.C.³

10
- 0030763355
- Properties of cytochrome P450 isoenzymes and their substrates. II. Properties of cytochrome P450 substrates
- (1997) Drug Dev. Today , vol.2 , pp. 479-486
- Smith, D.A.¹ Ackland, M.J.² Jones, B.C.³

11
- 2042440042
- The Camitro Corporation, 4040 Campbell Avenue, Menlo Park, California 94025, USA (www.camitro.com)

12
- 0028534521
- META 1. A program for the evaluation of metabolic transformation of chemicals
- (1994) J. Chem. Inf. Comput. Sci. , vol.34 , pp. 1320-1325
- Klopman, G.¹ Dimayuga, M.² Talafous, J.³

13
- 0028534522
- META 2. A dictionary model of mammalian xenobiotic metabolism
- (1994) J. Chem. Inf. Comput. Sci. , vol.34 , pp. 1326-1333
- Talafous, J.¹ Sayre, L.M.² Mieyal, J.J.³ Klopman, G.⁴

14
- 0023965741
- SMILES, a chemical language and information system. 1. Introduction to methodology and encoding rules
- (1988) J. Chem. Inf. Comput. Sci. , vol.28 , pp. 31-36
- Weininger, D.¹

15
- 2042510011
- MDLI connection table formats are published online at www.mdli.com.

16
- 0031089553
- META 3. A genetic algorithm for metabolic transform priorities optimization
- (1997) J. Chem. Inf. Comput. Sci. , vol.37 , pp. 329-334
- Klopman, G.¹ Tu, M.H.² Talafous, J.³

17
- 0033423672
- META 4. Prediction of the metabolism of polycyclic aromatic hydrocarbons
- (1999) Theor. Chem. Acc. , vol.102 , pp. 33-38
- Klopman, G.¹ Tu, M.H.² Fan, B.T.³

18
- 0001376350
- META: A program for the prediction of the products of mammalian metabolism of xenobiotics
- P.W. Erhardt (Ed.), Blackwell, Oxford
- (1999) Drug Metabolism, Databases in High-throughput Testing During Drug Design and Development , pp. 271-276
- Klopman, G.¹ Tu, M.H.²

19
- 2042472458
- CompuDrug International, Inc., P.O.B. 160, Budapest, 1255, Hungary (www.compudrug.com)

20
- 0024027564
- Predicting metabolic pathways by logic programming
- (1988) J. Mol. Graphics , vol.6 , pp. 80-86
- Darvas, F.¹

21
- 0008690929
- MetabolExpert, an expert system for predicting metabolism of substances
- K. Kaiser (Ed.), Riedel, Dordrecht
- (1987) QSAR in Environmental Toxicology , pp. 71-81
- Darvas, F.¹

22
- 0017035654
- Marcel Dekker, New York
- (1976) Drug Metabolism: Chemical and Biochemical Aspects
- Testa, B.¹ Jenner, P.²

23
- 0008715648
- VEB, Berlin
- (1963) Biotransformation von Arzneimitteln
- Pfeifer, S.¹ Borchert, H.²

24
- 0008690650
- Knowledge based expert systems for toxicity and metabolism prediction
- P.W. Erhardt (Ed.), Blackwell, Oxford
- (1999) Drug Metabolism, Databases in High-throughput Testing During Drug Design and Development , pp. 289-296
- Greene, N.¹

25
- 0032619762
- Knowledge-based expert systems for toxicity and metabolism prediction: DEREK, StAR, and METEOR
- (1999) SAR QSAR Environ. Res. , vol.10 , pp. 299-313
- Greene, N.¹ Judson, P.² Langowski, J.³ Marchant, C.A.⁴

26
- 0030676982
- Representation of chemical structures in knowledge-based systems: The StAR system
- (1997) J. Chem. Inf. Comput. Sci. , vol.37 , pp. 117-123
- Tonnelier, C.A.G.¹ Fox, J.² Judson, P.N.³ Krause, P.J.⁴ Pappas, N.⁵ Patel, M.⁶

27
- 0030188323
- Using new reasoning technology in chemical information systems
- (1996) J. Chem. Inf. Comput. Sci. , vol.36 , pp. 621-624
- Judson, P.N.¹ Fox, J.² Krause, P.J.³

28
- 2042476984
- Daylight Chemical Information Systems Inc., Suite 360, 27401 Los Altos, Mission Viejo, CA 92691, USA (www.daylight.com)

29
- 2042446027
- MDL Headquarters, MDL Information Systems, Inc., 14600 Catalina Street, San Leandro, CA 94577, USA. (www.mdli.com)

30
- 2042543082

31
- 0003580790
- Biotransformations
- Cambridge, UK
- (1988) Royal Society of Chemistry , vol.1-7
- Hawkins, D.R.¹

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.