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33750373834
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Biospherics gets patent on use of tagatose for anemia and hemophilia
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353553 Biospherics Inc PRESS RELEASE January 26
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353553 Biospherics gets patent on use of tagatose for anemia and hemophilia. Biospherics Inc PRESS RELEASE 2000 January 26
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Spherix to get patent on use of tagatose as drug to improve fertility
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407255 Biospherics, Inc PRESS RELEASE April 26
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407255 Spherix to get patent on use of tagatose as drug to improve fertility. Biospherics, Inc PRESS RELEASE 2001 April 26
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Spherix announces first sale of Naturlose for pharmaceutical use
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564588 Spherix Inc PRESS RELEASE October 14
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564588 Spherix announces first sale of Naturlose for pharmaceutical use. Spherix Inc PRESS RELEASE 2004 October 14
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(2004)
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33750290388
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Health benefits of tagatose praised in recent studies
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607768 Spherix Inc PRESS RELEASE June 16
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607768 Health benefits of tagatose praised in recent studies. Spherix Inc PRESS RELEASE 2005 June 16
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(2005)
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Spherix given FDA OK to begin phase III diabetes trial
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638977 Spherix Inc PRESS RELEASE December 06
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638977 Spherix given FDA OK to begin phase III diabetes trial. Spherix Inc PRESS RELEASE 2005 December 06
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(2005)
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Spherix chooses ENVIRON to assist with diabetes clinical trial
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644381 Spherix Inc PRESS RELEASE January 10
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644381 Spherix chooses ENVIRON to assist with diabetes clinical trial. Spherix Inc PRESS RELEASE 2006 January 10
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Spherix plans Australian phase III diabetes trial of Naturlose
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669134 Spherix Inc PRESS RELEASE May 23
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669134 Spherix plans Australian phase III diabetes trial of Naturlose. Spherix Inc PRESS RELEASE 2006 May 23
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38049184050
-
The metabolic effects of dietary supplementation with D-tagatose in patients with type 2 diabetes
-
672483
-
672483 The metabolic effects of dietary supplementation with D-tagatose in patients with type 2 diabetes. Donner TW DIABETES 2006 66 6 Suppl 1 461P
-
(2006)
Diabetes
, vol.66
, Issue.6 SUPPL. 1
-
-
Donner, T.W.1
-
9
-
-
0036011228
-
Tagatose, the new GRAS sweetener and health product
-
674842
-
674842 Tagatose, the new GRAS sweetener and health product. Levin GV J MED FOOD 2002 5 1 23-36
-
(2002)
J Med Food
, vol.5
, Issue.1
, pp. 23-36
-
-
Levin, G.V.1
-
10
-
-
0033188539
-
D-Tagatose, a novel hexose: Acute effects on carbohydrate tolerance in subjects with and without type 2 diabetes
-
674844
-
674844 D-Tagatose, a novel hexose: Acute effects on carbohydrate tolerance in subjects with and without type 2 diabetes. Donner TW, Wilber JF, Ostrowski D DIABETES OBESITY METAB 1999 1 5 285-291
-
(1999)
Diabetes Obesity Metab
, vol.1
, Issue.5
, pp. 285-291
-
-
Donner, T.W.1
Wilber, J.F.2
Ostrowski, D.3
-
11
-
-
0033023606
-
Characteristics and significance of D-tagatose-induced liver enlargement in rats: An interpretative review
-
674845
-
674845 Characteristics and significance of D-tagatose-induced liver enlargement in rats: An interpretative review. Bar A REGUL TOXICOL PHARMACOL 1999 29 2 S83-S93
-
(1999)
Regul Toxicol Pharmacol
, vol.29
, Issue.2
-
-
Bar, A.1
-
12
-
-
0033021050
-
Effects of acute and repeated oral doses of D-tagatose on plasma uric acid in normal and diabetic humans
-
674846
-
674846 Effects of acute and repeated oral doses of D-tagatose on plasma uric acid in normal and diabetic humans. Saunders JP, Donner TW, Sadler JH, Levin GV, Makris NG REGUL TOXICOL PHARMACOL 1999 29 2 S57-S65
-
(1999)
Regul Toxicol Pharmacol
, vol.29
, Issue.2
-
-
Saunders, J.P.1
Donner, T.W.2
Sadler, J.H.3
Levin, G.V.4
Makris, N.G.5
-
15
-
-
0031882002
-
Antioxidant and cytoprotective properties of D-tagatose in cultured murine hepatocytes
-
674853
-
674853 Antioxidant and cytoprotective properties of D-tagatose in cultured murine hepatocytes. Paterna JC, Boess F, Staeubli A, Boelsterli UA TOXICOL APPL PHARMACOL 1998 148 1 117-125
-
(1998)
Toxicol Appl Pharmacol
, vol.148
, Issue.1
, pp. 117-125
-
-
Paterna, J.C.1
Boess, F.2
Staeubli, A.3
Boelsterli, U.A.4
-
16
-
-
0029989031
-
D-tagatose is a bulk sweetener with zero energy determined in rats
-
674854
-
674854 D-tagatose is a bulk sweetener with zero energy determined in rats. Livesey G, Brown JC J NUTR 1996 126 6 1601-1609
-
(1996)
J Nutr
, vol.126
, Issue.6
, pp. 1601-1609
-
-
Livesey, G.1
Brown, J.C.2
-
17
-
-
4243384621
-
Antidiabetic effect of D-tagatose in SHR/N-cp rats
-
674855
-
674855 Antidiabetic effect of D-tagatose in SHR/N-cp rats. Szepesi B, Levin G, Zehner L, Saunders J FASEB J 1996 10 3 A461
-
(1996)
Faseb J
, vol.10
, Issue.3
-
-
Szepesi, B.1
Levin, G.2
Zehner, L.3
Saunders, J.4
-
18
-
-
0000850754
-
D-tagatose: A novel therapeutic adjunct for non-insulin-dependent diabetes
-
674856
-
674856 D-tagatose: A novel therapeutic adjunct for non-insulin-dependent diabetes. Donner T, Wilber J, Ostrowski D DIABETES 1996 45 Suppl 2 125A
-
(1996)
Diabetes
, vol.45
, Issue.SUPPL. 2
-
-
Donner, T.1
Wilber, J.2
Ostrowski, D.3
-
20
-
-
33750310155
-
Spherix highlights anti-diabetes drug progress
-
676414 Spherix Inc PRESS RELEASE June 29
-
676414 Spherix highlights anti-diabetes drug progress. Spherix Inc PRESS RELEASE 2006 June 29
-
(2006)
-
-
-
21
-
-
0042166232
-
Contributions of fasting and postprandial plasma glucose increments to the overall diurnal hyperglycemia of type 2 diabetic patients: Variations with increasing levels of HbA1c
-
679421
-
679421 Contributions of fasting and postprandial plasma glucose increments to the overall diurnal hyperglycemia of type 2 diabetic patients: Variations with increasing levels of HbA1c. Monnier L, Lapinski H, Colette C DIABETES CARE 2003 26 3 881-885
-
(2003)
Diabetes Care
, vol.26
, Issue.3
, pp. 881-885
-
-
Monnier, L.1
Lapinski, H.2
Colette, C.3
-
22
-
-
33644932611
-
Postprandial glucose regulation: New data and new implications
-
679423
-
679423 Postprandial glucose regulation: New data and new implications. Leiter LA, Ceriello A, Davidson JA, Hanefeld M, Monnier L, Owens DR, Tajima N, Tuomilehto J CLIN THER 2005 27 Suppl 2 S42-S56
-
(2005)
Clin Ther
, vol.27
, Issue.SUPPL. 2
-
-
Leiter, L.A.1
Ceriello, A.2
Davidson, J.A.3
Hanefeld, M.4
Monnier, L.5
Owens, D.R.6
Tajima, N.7
Tuomilehto, J.8
-
23
-
-
0034641568
-
Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): Prospective observational study
-
679424
-
679424 Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): Prospective observational study. Stratton IM, Adler AI, Neil HA, Matthews DR, Manley SE, Cull CA, Hadden D, Turner RC, Holman RR Br Med J 2000 321 7258 405-412
-
(2000)
Br Med J
, vol.321
, Issue.7258
, pp. 405-412
-
-
Stratton, I.M.1
Adler, A.I.2
Neil, H.A.3
Matthews, D.R.4
Manley, S.E.5
Cull, C.A.6
Hadden, D.7
Turner, R.C.8
Holman, R.R.9
-
24
-
-
0346727578
-
Acarbose reduces the risk for myocardial infarction in type 2 diabetic patients: Meta-analysis of seven long-term studies
-
679426
-
679426 Acarbose reduces the risk for myocardial infarction in type 2 diabetic patients: Meta-analysis of seven long-term studies. Hanefeld M, Cagatay M, Petrowitsch T, Neuser D, Petzinna D, Rupp M EUR HEART J 2004 25 1 10-16
-
(2004)
Eur Heart J
, vol.25
, Issue.1
, pp. 10-16
-
-
Hanefeld, M.1
Cagatay, M.2
Petrowitsch, T.3
Neuser, D.4
Petzinna, D.5
Rupp, M.6
-
25
-
-
33745302884
-
The natural course of β-cell function in nondiabetic and diabetic individuals: The insulin resistance atherosclerosis study
-
679427
-
679427 The natural course of β-cell function in nondiabetic and diabetic individuals: The insulin resistance atherosclerosis study. Festa A, Williams K, D'Agostino R Jr, Wagenknecht LE, Haffner SM DIABETES 2006 55 4 1114-1120
-
(2006)
Diabetes
, vol.55
, Issue.4
, pp. 1114-1120
-
-
Festa, A.1
Williams, K.2
D'Agostino Jr., R.3
Wagenknecht, L.E.4
Haffner, S.M.5
-
26
-
-
32944473444
-
Increase in D-tagatose production rate by site-directed mutagenesis of L-arabinose isomerase from Geobacillus thermodenitrificans
-
679428
-
679428 Increase in D-tagatose production rate by site-directed mutagenesis of L-arabinose isomerase from Geobacillus thermodenitrificans. Oh HJ, Kim HJ, Oh DK BIOTECHNOL LETT 2006 28 3 145-149
-
(2006)
Biotechnol Lett
, vol.28
, Issue.3
, pp. 145-149
-
-
Oh, H.J.1
Kim, H.J.2
Oh, D.K.3
-
27
-
-
0015733836
-
The substrate and anomeric specificity of fructokinase
-
679429
-
679429 The substrate and anomeric specificity of fructokinase. Raushel FM, Cleland WW J BIOL CHEM 1973 248 23 8174-8177
-
(1973)
J Biol Chem
, vol.248
, Issue.23
, pp. 8174-8177
-
-
Raushel, F.M.1
Cleland, W.W.2
-
28
-
-
0032983853
-
Effect of D-tagatose on liver weight and glycogen content of rats
-
679438
-
679438 Effect of D-tagatose on liver weight and glycogen content of rats. Bar A, Lina BA, de Groot DM, de Bie B, Appel MJ REGUL TOXICOL PHARMACOL 1999 292 Pt2 S11-S28
-
(1999)
Regul Toxicol Pharmacol
, vol.292
, Issue.PART 2
-
-
Bar, A.1
Lina, B.A.2
de Groot, D.M.3
de Bie, B.4
Appel, M.J.5
-
29
-
-
0024804561
-
Lower fat deposition and energy utilization of growing rats fed diets containing sorbose
-
679439
-
679439 Lower fat deposition and energy utilization of growing rats fed diets containing sorbose. Furuse M, Tamura Y, Matsuda S, Shimizu T, Okumura J COMP BIOCHEM PHYSIOL A 1989 94 4 813-817
-
(1989)
Comp Biochem Physiol A
, vol.94
, Issue.4
, pp. 813-817
-
-
Furuse, M.1
Tamura, Y.2
Matsuda, S.3
Shimizu, T.4
Okumura, J.5
-
30
-
-
0030961932
-
Enlargement glycogen store in rat liver and muscle by fructose-diet intake and exercise training
-
679440
-
679440 Enlargement glycogen store in rat liver and muscle by fructose-diet intake and exercise training. Murakami T, Shimomura Y, Fujitsuka N, Sokabe M, Okamura K, Sakamoto S J APPL PHYSIOL 1997 82 3 772-775
-
(1997)
J Appl Physiol
, vol.82
, Issue.3
, pp. 772-775
-
-
Murakami, T.1
Shimomura, Y.2
Fujitsuka, N.3
Sokabe, M.4
Okamura, K.5
Sakamoto, S.6
-
31
-
-
0014044939
-
Metabolic responses of white rats to balanced and imbalanced protein fed with different carbohydrates in 15% and 5% fat diets
-
679441
-
679441 Metabolic responses of white rats to balanced and imbalanced protein fed with different carbohydrates in 15% and 5% fat diets. Gaertner EB, Carroll C J NUTR 1967 91 1 69-78
-
(1967)
J Nutr
, vol.91
, Issue.1
, pp. 69-78
-
-
Gaertner, E.B.1
Carroll, C.2
-
32
-
-
0034981831
-
Stimulating effects of low-dose fructose on insulin-stimulated hepatic glycogen synthesis in humans
-
679442
-
679442 Stimulating effects of low-dose fructose on insulin-stimulated hepatic glycogen synthesis in humans. Petersen KF, Laurent D, Yu C, Cline GW, Shulman GI DIABETES 2001 50 6 1263-1268
-
(2001)
Diabetes
, vol.50
, Issue.6
, pp. 1263-1268
-
-
Petersen, K.F.1
Laurent, D.2
Yu, C.3
Cline, G.W.4
Shulman, G.I.5
-
33
-
-
0030205126
-
Effects of dietary carbohydrates on glucose and lipid metabolism in golden Syrian hamsters
-
679443
-
679443 Effects of dietary carbohydrates on glucose and lipid metabolism in golden Syrian hamsters. Kasim-Karakas SE, Vriend H, Almario R, Chow LC, Goodman MN J LAS CLIN MED 1996 128 2 208-213
-
(1996)
J Las Clin Med
, vol.128
, Issue.2
, pp. 208-213
-
-
Kasim-Karakas, S.E.1
Vriend, H.2
Almario, R.3
Chow, L.C.4
Goodman, M.N.5
-
34
-
-
0035200476
-
Small-bowel absorption of D-tagatose and related effects on carbohydrate digestibility: An ileostomy study
-
679444
-
679444 Small-bowel absorption of D-tagatose and related effects on carbohydrate digestibility: An ileostomy study. Normen L, Laerke HN, Jensen BB, Langkilde AM, Andersson H AM J CLIN NUTR 2001 73 1 105-110
-
(2001)
Am J Clin Nutr
, vol.73
, Issue.1
, pp. 105-110
-
-
Normen, L.1
Laerke, H.N.2
Jensen, B.B.3
Langkilde, A.M.4
Andersson, H.5
-
35
-
-
0033839921
-
The acute effect of D-tagatose on food intake in human subjects
-
679445
-
679445 The acute effect of D-tagatose on food intake in human subjects. Buemann B, Toubro S, Raben A, Blundell J, Astrup A BR J NUTR 2000 84 227-231
-
(2000)
Br J Nutr
, vol.84
, pp. 227-231
-
-
Buemann, B.1
Toubro, S.2
Raben, A.3
Blundell, J.4
Astrup, A.5
-
36
-
-
0032983854
-
Human tolerance to a single, high dose of D-tagatose
-
679447
-
679447 Human tolerance to a single, high dose of D-tagatose. Buemann B, Toubro S, Raben A, Astrup A REGUL TOXICOL PHARMACOL 1999 29 2 Pt 2 S66-S70
-
(1999)
Regul Toxicol Pharmacol
, vol.29
, Issue.2 PART 2
-
-
Buemann, B.1
Toubro, S.2
Raben, A.3
Astrup, A.4
-
37
-
-
0031691879
-
D-Tagatose, a stereolsomer of D-fructose, increases hydrogen production in humans without affecting 24-hour energy expenditure or respiratory exchange ratio
-
679448
-
679448 D-Tagatose, a stereolsomer of D-fructose, increases hydrogen production in humans without affecting 24-hour energy expenditure or respiratory exchange ratio. Buemann B, Toubro S, Astrup A J NUTR 1998 128 9 1481-1486
-
(1998)
J Nutr
, vol.128
, Issue.9
, pp. 1481-1486
-
-
Buemann, B.1
Toubro, S.2
Astrup, A.3
-
39
-
-
0033921779
-
In vitro fermentation pattern of D-tagatose is affected by adaptation of the microbiota from the gastrointestinal tract of pigs
-
679450
-
679450 In vitro fermentation pattern of D-tagatose is affected by adaptation of the microbiota from the gastrointestinal tract of pigs. Laerke, HN, Jensen BB, Hojsgaard S J NUTR 2000 130 7 1772-1779
-
(2000)
J Nutr
, vol.130
, Issue.7
, pp. 1772-1779
-
-
Laerke, H.N.1
Jensen, B.B.2
Hojsgaard, S.3
-
40
-
-
0032907118
-
D-Tagatose has low small intestinal digestibility but high large intestinal fermentability in pigs
-
679451
-
679451 D-Tagatose has low small intestinal digestibility but high large intestinal fermentability in pigs. Laerke HN, Jensen BB J NUTR 1999 129 5 1002-1009
-
(1999)
J Nutr
, vol.129
, Issue.5
, pp. 1002-1009
-
-
Laerke, H.N.1
Jensen, B.B.2
-
41
-
-
0034487957
-
Acute fructose administration decreases the glycemic response to an oral glucose tolerance test in normal adults
-
679452
-
679452 Acute fructose administration decreases the glycemic response to an oral glucose tolerance test in normal adults. Moore MC, Cherrington AD, Mann SL, Davis SN J CLIN ENDOCRINOL METAB 2000 85 12 4515-4519
-
(2000)
J Clin Endocrinol Metab
, vol.85
, Issue.12
, pp. 4515-4519
-
-
Moore, M.C.1
Cherrington, A.D.2
Mann, S.L.3
Davis, S.N.4
-
42
-
-
0035514687
-
Acute fructose administration improves oral glucose tolerance in adults with type 2 diabetes
-
679453
-
679453 Acute fructose administration improves oral glucose tolerance in adults with type 2 diabetes. Moore MC, Davis SN, Mann SL, Cherrington AD DIABETES CARE 2001 24 11 1882-1887
-
(2001)
Diabetes Care
, vol.24
, Issue.11
, pp. 1882-1887
-
-
Moore, M.C.1
Davis, S.N.2
Mann, S.L.3
Cherrington, A.D.4
-
43
-
-
0034998602
-
Effect of oral D-tagatose on liver volume and hepatic glycogen accumulation in healthy male volunteers
-
679454
-
679454 Effect of oral D-tagatose on liver volume and hepatic glycogen accumulation in healthy male volunteers. Boesch C, Ith M, Jung B, Bruegger K, Erban S, Diamantis I, Kreis R, Bar A REGUL TOXICOL PHARMACOL 2001 33 2 257-267
-
(2001)
Regul Toxicol Pharmacol
, vol.33
, Issue.2
, pp. 257-267
-
-
Boesch, C.1
Ith, M.2
Jung, B.3
Bruegger, K.4
Erban, S.5
Diamantis, I.6
Kreis, R.7
Bar, A.8
-
44
-
-
0028039062
-
Control of glucokinase translocation in rat hepatocytes by sorbitol and the cytosolic redox state
-
679456
-
679456 Control of glucokinase translocation in rat hepatocytes by sorbitol and the cytosolic redox state. Agius L BIOCHEM J 1994 298 1 237-243
-
(1994)
Biochem J
, vol.298
, Issue.1
, pp. 237-243
-
-
Agius, L.1
-
45
-
-
0036066247
-
Inclusion of low amounts of fructose with an intraduodenal glucose load markedly reduces postprandial hyperglycemia and hyperinsulinemia in the conscious dog
-
679458
-
679458 Inclusion of low amounts of fructose with an intraduodenal glucose load markedly reduces postprandial hyperglycemia and hyperinsulinemia in the conscious dog. Shiota M, Moore MC, Galassetti P, Monohan M, Neal DW, Shulman GI, Cherrington AD DIABETES 2002 51 2 469-478
-
(2002)
Diabetes
, vol.51
, Issue.2
, pp. 469-478
-
-
Shiota, M.1
Moore, M.C.2
Galassetti, P.3
Monohan, M.4
Neal, D.W.5
Shulman, G.I.6
Cherrington, A.D.7
-
47
-
-
18644362774
-
Dietary fructose: Implications for dysregulation of energy homeostasis and lipid/carbohydrate metabolism
-
681996
-
681996 Dietary fructose: Implications for dysregulation of energy homeostasis and lipid/carbohydrate metabolism. Havel PJ NUTR REV 2005 63 5 133-157
-
(2005)
Nutr Rev
, vol.63
, Issue.5
, pp. 133-157
-
-
Havel, P.J.1
-
48
-
-
23944443756
-
Hepatic adaptations to sucrose and fructose
-
682001
-
682001 Hepatic adaptations to sucrose and fructose. Bizeau ME, Pagliassotti MJ METABOLISM 2005 54 9 1189-1201
-
(2005)
Meatabolism
, vol.54
, Issue.9
, pp. 1189-1201
-
-
Bizeau, M.E.1
Pagliassotti, M.J.2
-
49
-
-
0033897686
-
D-Tagatose, a sterecisomer of D-fructose, increases blood uric acid concentration
-
682002
-
682002 D-Tagatose, a sterecisomer of D-fructose, increases blood uric acid concentration. Buemann B, Toubro S, Holst JJ, Rehfeld JF, Bibby BM, Astrup A METABOLISM 2000 49 8 969-976
-
(2000)
Metabolism
, vol.49
, Issue.8
, pp. 969-976
-
-
Buemann, B.1
Toubro, S.2
Holst, J.J.3
Rehfeld, J.F.4
Bibby, B.M.5
Astrup, A.6
-
50
-
-
0033787522
-
31P-magnetic resonance spectroscopy
-
682003
-
31P-magnetic resonance spectroscopy. Buemann B, Gesmar H, Astrup A, Quistorff B METABOLISM 2000 49 10 1335-1339
-
(2000)
Metabolism
, vol.49
, Issue.10
, pp. 1335-1339
-
-
Buemann, B.1
Gesmar, H.2
Astrup, A.3
Quistorff, B.4
-
51
-
-
33750342683
-
Spherix signs Anaclim to support diabetes clinical trial
-
683571 Spherix Inc PRESS RELEASE August 10
-
683571 Spherix signs Anaclim to support diabetes clinical trial. Spherix Inc PRESS RELEASE 2006 August 10
-
(2006)
-
-
-
52
-
-
0842312437
-
A systematic review of the clinical effectiveness of orlistat used for the management of obesity
-
685683
-
685683 A systematic review of the clinical effectiveness of orlistat used for the management of obesity. O'Meara S, Riemsma R, Shirran L, Mather L, ter Piet G OBES REV 2004 5 1 51-68
-
(2004)
Obes Rev
, vol.5
, Issue.1
, pp. 51-68
-
-
O'Meara, S.1
Riemsma, R.2
Shirran, L.3
Mather, L.4
ter Piet, G.5
-
53
-
-
0014424849
-
Liver adenine nucleatides: Fructose-induced depletion and its effect on protein synthesis
-
685690
-
685690 Liver adenine nucleatides: Fructose-induced depletion and its effect on protein synthesis. Maenpaa PH, Raivio KO, Kekomaki MP SCIENCE 1968 161 847 1253-1254
-
(1968)
Science
, vol.161
, Issue.847
, pp. 1253-1254
-
-
Maenpaa, P.H.1
Raivio, K.O.2
Kekomaki, M.P.3
|