메뉴 건너뛰기




Volumn 20, Issue 16, 2006, Pages 2021-2032

Immunophenotype of HIV+ patients during CD4 cell-monitored treatment interruption: Role of the IL-7/IL-7 receptor system

Author keywords

HAART; IL 7 receptor system; Lymphocyte activation; Therapy interruption; Viral load

Indexed keywords

ANTIRETROVIRUS AGENT; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR;

EID: 33750277044     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.aids.0000247575.41622.b1     Document Type: Article
Times cited : (22)

References (39)
  • 1
    • 2642709177 scopus 로고    scopus 로고
    • Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators
    • Palella FJ Jr, Delaney KM, Moorman AC, Loveless MO, Fuhrer J, Satten GA, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med 1998; 338:853-860.
    • (1998) N Engl J Med , vol.338 , pp. 853-860
    • Palella Jr., F.J.1    Delaney, K.M.2    Moorman, A.C.3    Loveless, M.O.4    Fuhrer, J.5    Satten, G.A.6
  • 2
    • 0033604038 scopus 로고    scopus 로고
    • Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy
    • Brinkman K, Smeitink JA, Romijn JA, Reiss P. Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy. Lancet 1999; 354:1112-1115.
    • (1999) Lancet , vol.354 , pp. 1112-1115
    • Brinkman, K.1    Smeitink, J.A.2    Romijn, J.A.3    Reiss, P.4
  • 3
    • 0037027996 scopus 로고    scopus 로고
    • Cardiomyopathy with mitochondrial damage associated with nucleoside reverse-transcriptase inhibitors
    • Frerichs FC, Dingemans KP, Brinkman K. Cardiomyopathy with mitochondrial damage associated with nucleoside reverse-transcriptase inhibitors. N Engl J Med 2002; 347:1895-1896.
    • (2002) N Engl J Med , vol.347 , pp. 1895-1896
    • Frerichs, F.C.1    Dingemans, K.P.2    Brinkman, K.3
  • 4
    • 0037076029 scopus 로고    scopus 로고
    • Changes in mitochondrial DNA as a marker of nucleoside toxicity in HIV infected patients
    • Côté HC, Brumme ZL, Craib KJ, Alexander CS, Wynhoven B, Ting L, et al. Changes in mitochondrial DNA as a marker of nucleoside toxicity in HIV infected patients. N Engl J Med 2002; 346:811-820.
    • (2002) N Engl J Med , vol.346 , pp. 811-820
    • Côté, H.C.1    Brumme, Z.L.2    Craib, K.J.3    Alexander, C.S.4    Wynhoven, B.5    Ting, L.6
  • 5
    • 0038708272 scopus 로고    scopus 로고
    • Prospective evaluation of the effects of antiretroviral therapy on body composition in HIV-1-infected men starting therapy
    • Mallon PW, Miller J, Cooper DA, Carr A. Prospective evaluation of the effects of antiretroviral therapy on body composition in HIV-1-infected men starting therapy. AIDS 2003; 17:971-979.
    • (2003) AIDS , vol.17 , pp. 971-979
    • Mallon, P.W.1    Miller, J.2    Cooper, D.A.3    Carr, A.4
  • 6
    • 1342310769 scopus 로고    scopus 로고
    • Antiretroviral nucleoside and nucleotide analogues and the mitochondria
    • Cossarizza A, Moyle G. Antiretroviral nucleoside and nucleotide analogues and the mitochondria. AIDS 2004; 18:137-151.
    • (2004) AIDS , vol.18 , pp. 137-151
    • Cossarizza, A.1    Moyle, G.2
  • 9
    • 0345404523 scopus 로고    scopus 로고
    • ISS-PART: A prospective, randomized, multicentre clinical trial of intermittent therapy in HIV+ subjects with persistent suppression of viral replication
    • Boston, February [abstract 66]
    • Vella S, Giuliano N, Palmisano L, Bucciardini R, Andreotti M, Arcieri R, et al. ISS-PART: a prospective, randomized, multicentre clinical trial of intermittent therapy in HIV+ subjects with persistent suppression of viral replication. Tenth Conference on Retroviruses and Opportunistic Infections. Boston, February 2003 [abstract 66].
    • (2003) Tenth Conference on Retroviruses and Opportunistic Infections
    • Vella, S.1    Giuliano, N.2    Palmisano, L.3    Bucciardini, R.4    Andreotti, M.5    Arcieri, R.6
  • 10
    • 13944262121 scopus 로고    scopus 로고
    • A prospective, randomized trial of structured treatment interruption for patients with chronic HIV type 1 infection
    • Cardiello PG, Hassink E, Ananworanich J, Srasuebkul P, Samor T, Mahanontharit A, et al. A prospective, randomized trial of structured treatment interruption for patients with chronic HIV type 1 infection. Clin Infect Dis 2005; 40:594-600.
    • (2005) Clin Infect Dis , vol.40 , pp. 594-600
    • Cardiello, P.G.1    Hassink, E.2    Ananworanich, J.3    Srasuebkul, P.4    Samor, T.5    Mahanontharit, A.6
  • 12
    • 0345119074 scopus 로고    scopus 로고
    • Prolonged treatment interruption after immunologic response to highly active antiretroviral therapy
    • Tarwater PM, Parish M, Gallant JE. Prolonged treatment interruption after immunologic response to highly active antiretroviral therapy. Clin Infect Dis 2003; 37:1541-1548.
    • (2003) Clin Infect Dis , vol.37 , pp. 1541-1548
    • Tarwater, P.M.1    Parish, M.2    Gallant, J.E.3
  • 13
    • 1642339461 scopus 로고    scopus 로고
    • Effect of prolonged discontinuation of successful antiretroviral therapy on CD4 T cells: A controlled, prospective trial
    • Maggiolo F, Ripamonti D, Gregis G, Quinzan G, Callegaro A, Suter F. Effect of prolonged discontinuation of successful antiretroviral therapy on CD4 T cells: a controlled, prospective trial. AIDS 2004; 18:439-446.
    • (2004) AIDS , vol.18 , pp. 439-446
    • Maggiolo, F.1    Ripamonti, D.2    Gregis, G.3    Quinzan, G.4    Callegaro, A.5    Suter, F.6
  • 14
    • 11244336872 scopus 로고    scopus 로고
    • Influence of prior structured treatment interruptions on the length of time without antiretroviral treatment in chronically HIV-infected subjects
    • Molto J, Ruiz L, Romeu J, Martinez-Picado J, Negredo E, Tural C, et al. Influence of prior structured treatment interruptions on the length of time without antiretroviral treatment in chronically HIV-infected subjects. AIDS Res Hum Retroviruses 2004; 20:1283-1288.
    • (2004) AIDS Res Hum Retroviruses , vol.20 , pp. 1283-1288
    • Molto, J.1    Ruiz, L.2    Romeu, J.3    Martinez-Picado, J.4    Negredo, E.5    Tural, C.6
  • 15
    • 23244437092 scopus 로고    scopus 로고
    • Highly active antiretroviral therapy (HAART) retreatment in patients on CD4-guided therapy achieved similar virologic suppression compared with patients on continuous HAART: The HIV Netherlands Australia Thailand Research Collaboration 001.4 study
    • Ananworanich J, Siangphoe U, Hill A, Cardiello P, Apateerapong W, Hirschel B, et al. Highly active antiretroviral therapy (HAART) retreatment in patients on CD4-guided therapy achieved similar virologic suppression compared with patients on continuous HAART: the HIV Netherlands Australia Thailand Research Collaboration 001.4 study. J Acquir Immune Defic Syndr 2005; 39:523-529.
    • (2005) J Acquir Immune Defic Syndr , vol.39 , pp. 523-529
    • Ananworanich, J.1    Siangphoe, U.2    Hill, A.3    Cardiello, P.4    Apateerapong, W.5    Hirschel, B.6
  • 17
    • 27144527399 scopus 로고    scopus 로고
    • Effect of treatment interruption monitored by CD4 cell count on mitochondrial DNA content in HIV-infected patients: A prospective study
    • Mussini C, Pinti M, Bugarini R, Borghi V, Nasi M, Nemes E, et al. Effect of treatment interruption monitored by CD4 cell count on mitochondrial DNA content in HIV-infected patients: a prospective study. AIDS 2005; 19:1627-1633.
    • (2005) AIDS , vol.19 , pp. 1627-1633
    • Mussini, C.1    Pinti, M.2    Bugarini, R.3    Borghi, V.4    Nasi, M.5    Nemes, E.6
  • 18
    • 33646937694 scopus 로고    scopus 로고
    • Thymic output and functionality of the IL-7/IL-7 receptor system in centenarians: Implications for the neolymphogenesis at the extreme limit of human life
    • Nasi M, Troiano L, Lugli E, Pinti M, Ferraresi R, Monterastelli E, et al. Thymic output and functionality of the IL-7/IL-7 receptor system in centenarians: implications for the neolymphogenesis at the extreme limit of human life. Aging Cell 2006; 5:167-175.
    • (2006) Aging Cell , vol.5 , pp. 167-175
    • Nasi, M.1    Troiano, L.2    Lugli, E.3    Pinti, M.4    Ferraresi, R.5    Monterastelli, E.6
  • 19
    • 27644558367 scopus 로고    scopus 로고
    • Characterization of cells with different mitochondrial membrane potential during apoptosis
    • Lugli E, Troiano L, Ferraresi R, Roat E, Prada N, Nasi M, et al. Characterization of cells with different mitochondrial membrane potential during apoptosis. Cytometry 2005; 68:28-35.
    • (2005) Cytometry , vol.68 , pp. 28-35
    • Lugli, E.1    Troiano, L.2    Ferraresi, R.3    Roat, E.4    Prada, N.5    Nasi, M.6
  • 20
    • 0033937718 scopus 로고    scopus 로고
    • Role of CD38 in HIV-1 infection: An epiphenomenon of T-cell activation or an active player in virus/host interactions?
    • Savarino A, Bottarel F, Malavasi F, Dianzani U. Role of CD38 in HIV-1 infection: an epiphenomenon of T-cell activation or an active player in virus/host interactions? AIDS 2000; 14:1079-1089.
    • (2000) AIDS , vol.14 , pp. 1079-1089
    • Savarino, A.1    Bottarel, F.2    Malavasi, F.3    Dianzani, U.4
  • 21
    • 0029006189 scopus 로고
    • Massive activation of immune cells with an intact T cell repertoire in acute human immunodeficiency virus syndrome
    • Cossarizza A, Ortolani C, Mussini C, Borghi V, Guaraldi G, Mongiardo N, et al. Massive activation of immune cells with an intact T cell repertoire in acute human immunodeficiency virus syndrome. J Infect Dis 1995; 172:105-112.
    • (1995) J Infect Dis , vol.172 , pp. 105-112
    • Cossarizza, A.1    Ortolani, C.2    Mussini, C.3    Borghi, V.4    Guaraldi, G.5    Mongiardo, N.6
  • 22
    • 24644469032 scopus 로고    scopus 로고
    • Can highly active antiretroviral therapy be interrupted in patients with sustained moderate HIV RNA and > 400 CD4+ cells/microl? Impact on immunovirological parameters
    • Pellegrin I, Thiebaut R, Blanco P, Viallard JF, Schrive MH, Merel P, et al. Can highly active antiretroviral therapy be interrupted in patients with sustained moderate HIV RNA and > 400 CD4+ cells/microl? Impact on immunovirological parameters. J Med Virol 2005; 77:164-172.
    • (2005) J Med Virol , vol.77 , pp. 164-172
    • Pellegrin, I.1    Thiebaut, R.2    Blanco, P.3    Viallard, J.F.4    Schrive, M.H.5    Merel, P.6
  • 23
    • 0030668834 scopus 로고    scopus 로고
    • Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4+ cell count, soluble immune activation markers, or combinations of HLA-DR and CD38 expression
    • Liu Z, Cumberland WG, Hultin LE, Prince HE, Detels R, Giorgi JV. Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4+ cell count, soluble immune activation markers, or combinations of HLA-DR and CD38 expression. J Acquir Immune Defic Syndr Hum Retrovirol 1997; 16:83-92.
    • (1997) J Acquir Immune Defic Syndr Hum Retrovirol , vol.16 , pp. 83-92
    • Liu, Z.1    Cumberland, W.G.2    Hultin, L.E.3    Prince, H.E.4    Detels, R.5    Giorgi, J.V.6
  • 24
    • 0038725688 scopus 로고    scopus 로고
    • Apoptosis as an HIV strategy to escape immune attack
    • Marie-Lise Gougeon. Apoptosis as an HIV strategy to escape immune attack. Nat Rev Immunol 2003, 3:392-404.
    • (2003) Nat Rev Immunol , vol.3 , pp. 392-404
    • Gougeon, M.-L.1
  • 25
    • 0031018842 scopus 로고    scopus 로고
    • Mitochondria alterations and dramatic tendency to undergo apoptosis in peripheral blood lymphocytes during acute HIV syndrome
    • Cossarizza A, Mussini C, Mongiardo N, Borghi V, Sabbatini A, De Rienzo B, et al. Mitochondria alterations and dramatic tendency to undergo apoptosis in peripheral blood lymphocytes during acute HIV syndrome. AIDS 1997; 11:19-26.
    • (1997) AIDS , vol.11 , pp. 19-26
    • Cossarizza, A.1    Mussini, C.2    Mongiardo, N.3    Borghi, V.4    Sabbatini, A.5    De Rienzo, B.6
  • 26
    • 0034030616 scopus 로고    scopus 로고
    • Deregulation of the CD95/CD95L system in lymphocytes from patients with primary acute HIV infection
    • Cossarizza A, Stent G, Mussini C, Paganelli R, Borghi V, Nuzzo C, et al. Deregulation of the CD95/CD95L system in lymphocytes from patients with primary acute HIV infection. AIDS 2000; 14:345-355.
    • (2000) AIDS , vol.14 , pp. 345-355
    • Cossarizza, A.1    Stent, G.2    Mussini, C.3    Paganelli, R.4    Borghi, V.5    Nuzzo, C.6
  • 28
    • 0035471754 scopus 로고    scopus 로고
    • Interleukin-7: Master regulator of peripheral T-cell homeostasis?
    • Fry TJ, Mackall CL. Interleukin-7: master regulator of peripheral T-cell homeostasis? Trends Immunol 2001; 22:564-571.
    • (2001) Trends Immunol , vol.22 , pp. 564-571
    • Fry, T.J.1    Mackall, C.L.2
  • 29
    • 15844411342 scopus 로고    scopus 로고
    • Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation
    • Lang KS, Recher M, Navarini AA, Harris NL, Lohning M, Junt T, et al. Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation. Eur J Immunol 2005; 35:738-745.
    • (2005) Eur J Immunol , vol.35 , pp. 738-745
    • Lang, K.S.1    Recher, M.2    Navarini, A.A.3    Harris, N.L.4    Lohning, M.5    Junt, T.6
  • 30
    • 32944455546 scopus 로고    scopus 로고
    • IL-7Ralpha expression on CD4+ T lymphocytes decreases with HIV disease progression and inversely correlates with immune activation
    • Koesters SA, Alimonti JB, Wachihi C, Matu L, Anzala O, Kimani J, et al. IL-7Ralpha expression on CD4+ T lymphocytes decreases with HIV disease progression and inversely correlates with immune activation. Eur J Immunol 2006; 36:336-344.
    • (2006) Eur J Immunol , vol.36 , pp. 336-344
    • Koesters, S.A.1    Alimonti, J.B.2    Wachihi, C.3    Matu, L.4    Anzala, O.5    Kimani, J.6
  • 31
    • 0035138982 scopus 로고    scopus 로고
    • Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: Implications for T-cell homeostasis
    • Napolitano LA, Grant RM, Deeks SG, Schmidt D, De Rosa SC, Herzenberg LA, et al. Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis. Nat Med 2001; 7:73-79.
    • (2001) Nat Med , vol.7 , pp. 73-79
    • Napolitano, L.A.1    Grant, R.M.2    Deeks, S.G.3    Schmidt, D.4    De Rosa, S.C.5    Herzenberg, L.A.6
  • 32
    • 0038545516 scopus 로고    scopus 로고
    • Homeostasis of naive and memory CD4+ T cells: IL-2 and IL-7 differentially regulate the balance between proliferation and Fas-mediated apoptosis
    • Jaleco S, Swainson L, Dardalhon V, Burjanadze M, Kinet S, Taylor N. Homeostasis of naive and memory CD4+ T cells: IL-2 and IL-7 differentially regulate the balance between proliferation and Fas-mediated apoptosis. J Immunol 2003; 171:61-68.
    • (2003) J Immunol , vol.171 , pp. 61-68
    • Jaleco, S.1    Swainson, L.2    Dardalhon, V.3    Burjanadze, M.4    Kinet, S.5    Taylor, N.6
  • 33
    • 0035905477 scopus 로고    scopus 로고
    • Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells
    • Geginat J, Sallusto F, Lanzavecchia A. Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells. J Exp Med 2001; 194:1711-1719.
    • (2001) J Exp Med , vol.194 , pp. 1711-1719
    • Geginat, J.1    Sallusto, F.2    Lanzavecchia, A.3
  • 34
    • 0034332403 scopus 로고    scopus 로고
    • Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo
    • Schluns KS, Kieper WC, Jameson SC, Lefrancois L. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat Immunol 2000; 1:426-432.
    • (2000) Nat Immunol , vol.1 , pp. 426-432
    • Schluns, K.S.1    Kieper, W.C.2    Jameson, S.C.3    Lefrancois, L.4
  • 35
    • 33645072224 scopus 로고    scopus 로고
    • CD127 expression and regulation are altered in the memory CD8 T cells of HIV-infected patients - Reversal by highly active anti-retroviral therapy (HAART)
    • Colle JH, Moreau JL, Fontanet A, Lambotte O, Joussemet M, Delfraissy JF, et al. CD127 expression and regulation are altered in the memory CD8 T cells of HIV-infected patients - reversal by highly active anti-retroviral therapy (HAART). Clin Exp Immunol 2006; 143:398-403.
    • (2006) Clin Exp Immunol , vol.143 , pp. 398-403
    • Colle, J.H.1    Moreau, J.L.2    Fontanet, A.3    Lambotte, O.4    Joussemet, M.5    Delfraissy, J.F.6
  • 36
    • 20044382810 scopus 로고    scopus 로고
    • Loss of CD127 expression defines an expansion of effector CD8+ T cells in HIV-infected individuals
    • Paiardini M, Cervasi B, Albrecht H, Muthukumar A, Dunham R, Gordon S, et al. Loss of CD127 expression defines an expansion of effector CD8+ T cells in HIV-infected individuals. J Immunol 2005; 174:2900-2909.
    • (2005) J Immunol , vol.174 , pp. 2900-2909
    • Paiardini, M.1    Cervasi, B.2    Albrecht, H.3    Muthukumar, A.4    Dunham, R.5    Gordon, S.6
  • 37
    • 22544463406 scopus 로고    scopus 로고
    • Long-term follow-up of asymptomatic HIV-infected patients who discontinued antiretroviral therapy
    • Fernandez Guerrero ML, Rivas P, Molina M, Garcia R, De Gorgolas M. Long-term follow-up of asymptomatic HIV-infected patients who discontinued antiretroviral therapy. Clin Infect Dis 2005; 41:390-394.
    • (2005) Clin Infect Dis , vol.41 , pp. 390-394
    • Fernandez Guerrero, M.L.1    Rivas, P.2    Molina, M.3    Garcia, R.4    De Gorgolas, M.5
  • 39
    • 33745070786 scopus 로고    scopus 로고
    • Episodic CD4-guided use of ART is inferior to continuous therapy: Results of the SMART study
    • Denver, CO, February [abstract 1061b]
    • El-Sadr W, Neaton J. Episodic CD4-guided use of ART is inferior to continuous therapy: results of the SMART study. Thirteenth Conference on Retroviruses and Opportunistic Infections. Denver, CO, February 2006 [abstract 1061b].
    • (2006) Thirteenth Conference on Retroviruses and Opportunistic Infections
    • El-Sadr, W.1    Neaton, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.