Function of the rat carotid body chemoreceptors in ageing

Journal of Neurochemistry

Volumn 99, Issue 3, 2006, Pages 711-723

  Conde, Silvia V ^a,b   Obeso, Ana ^a   Rigual, Ricardo ^a   Monteiro, Emilia C ^b   Gonzalez, Constancio ^a  

^a UNIVERSITY OF VALLADOLID   (Spain)

^b NOVA MEDICAL SCHOOL   (Portugal)

Author keywords

Ageing; Carotid body; Catecholamines; Dopamine; Hypoxia; Parkinson's disease

Indexed keywords

CATECHOLAMINE;

AGE; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAROTID BODY CHEMORECEPTOR; CAROTID SINUS NERVE; CATECHOLAMINE RELEASE; CATECHOLAMINE SYNTHESIS; CONTROLLED STUDY; DEPOLARIZATION; HYPERCAPNIA; HYPOXIA; MORPHOMETRICS; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; RAT STRAIN; RESPIRATORY ACIDOSIS; RESPIRATORY DRIVE;

ACIDOSIS; AGING; ANIMALS; ANOXIA; CAROTID BODY; CATECHOLAMINES; CATECHOLS; CHEMORECEPTOR CELLS; CHEMORECEPTORS; FEMALE; HYPERCAPNIA; MALE; POTASSIUM; RATS; RATS, SPRAGUE-DAWLEY; SEASONS; TYROSINE; TYROSINE 3-MONOOXYGENASE;

MAMMALIA;

EID: 33750080433     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04094.x     Document Type: Article

References (56)

1. Arjona V., Minguez-Castellanos A., Montoro R. J. et al. (2003) Auto-transplantation of human carotid body cell aggregates for treatment of Parkinson's disease. Neurosurgery 53, 321-328.
2. Behan M., Zabka A. G. and Mitchell G. S. (2002) Age and gender effects on serotonin-dependent plasticity in respiratory motor control. Respir. Physiol. Neurobiol. 13, 65-77.
3. Bisgard G. E., Forster H. V., Orr J. A., Buss D. D., Rawlings C. A. and Rasmussen B. (1976) Hypoventilation in ponies after carotid body denervation. J. Appl. Physiol. 40, 184-190.
4. Bosboom J. L., Stoffers D. and Wolters E. Ch (2003) The role of acetylcholine and dopamine in dementia and psychosis in Parkinson's disease. J. Neural Transm. Suppl. 65, 185-195.
5. Busch M. A., Bisgard G. E., Mesina J. E. and Forster H. V. (1983) The effects of unilateral carotid body excision on ventilatory control in goats. Respir. Physiol. 54, 353-361.
6. Cerveri I., Zoia M. C., Fanfulla F., Spagnolatti L., Berrayah L., Grassi M. and Tinelli C. (1995) Reference values of arterial oxygen tension in the middle-aged and elderly. Am. J. Respir. Crit. Care Med. 152, 934-941.
7. Chan E. D. and Welsh C. H. (1998) Geriatric respiratory medicine. Chest 114, 1704-1733.
8. Cragg P. A. and Khrisanapant W. (1994) Is the second carotid body redundant? Adv. Exp. Med. Biol. 360, 297-299.
9. De Souza R. R. (2002) Aging of myocardial collagen. Biogerontology 3, 325-335.
10. Di Giulio C., Di Muzio M., Sabatino G., Spoletini L., Amicarelli F., Di Ilio C. and Modesti A. (1998) Effect of chronic hyperoxia on young and old rat carotid body ultrastructure. Exp. Gerontol. 33, 319-329.
11. Di Giulio C., Cacchio M., Bianchi G., Rapino C. and Di Ilio C. (2003) Selected contribution: Carotid body as a model for aging studies: is there a link between oxygen and aging? J. Appl. Physiol. 95, 1755-1758.
12. Fernandez-Espejo E., Armengol J. A., Flores J. A., Galan-Rodriguez B. and Ramiro S. (2005) Cells of the sympathoadrenal lineage: biological properties as donor tissue for cell-replacement therapies for Parkinson's disease. Brain Res. Brain Res. Rev. 49, 343-354.
13. Fidone S. and Gonzalez C. (1982) Catecholamine synthesis in rabbit carotid body in vitro. J. Physiol. 333, 69-79.
14. Fidone S. and Gonzalez C. (1986) Peripheral chemoreceptors: initiation and control of discharges, in Handbook of Physiology. The Respiratory System II (Fishman, A. P., ed.), pp. 247-312. American Physiology Society, Bethesda, MD.
15. Fidone S., Gonzalez C. and Yoshizaki K. (1982) Effects of low oxygen on the release of dopamine from the rabbit carotid body in vitro. J. Physiol. 333, 93-110.
16. Fitzgerald R. S. and Parks D. C. (1971) Effect of hypoxia on carotid chemoreceptor response to carbon dioxide in cats. Respir. Physiol. 12, 218-229.
17. Fordyce W. E. (1987) Hypoxic ventilatory control in the awake cat 5 years after carotid body resection. Respir. Physiol. 69, 209-225.
18. Forster H. V., Pan L. G., Lowry T. F., Serra A., Wenninger J. and Martino P. (2000) Important role of carotid chemoreceptor afferents in control of breathing of adult and neonatal mammals. Respir. Physiol. 119, 199-208.
19. 2 and hydroxyl radicals but not glutathione-protein- mixed disulfides. J. Neurochem. 82, 66-74.
20. Gonzalez E., Rigual R., Fidone S. J. and Gonzalez C. (1987) Mechanisms for termination of the action of dopamine in carotid body chemoreceptors. J. Auton. Nerv. Syst. 18, 249-259.
21. Gonzalez C., Almaraz L., Obeso A. and Rigual R. (1992) Oxygen and acid chemoreception in the carotid body chemoreceptors. Trends Neurosci. 15, 146-153.
22. Gonzalez C., Almaraz L., Obeso A. and Rigual R. (1994) Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol. Rev. 74, 829-898.
23. Gonzalez C., Rocher R. and Zapata P. (2003) Arterial chemoreceptors: cellular and molecular mechanisms in the adaptative and homeostatic function of the carotid body. Rev. Neurol. 36, 239-254.
24. Gunnarsson L., Tokics L., Brismar B. and Hedenstierna G. (1996) Influence of age on circulation and arterial blood gases in man. Acta Anaesthesiol. Scand. 40, 237-443.
25. Harnois C. and Di Paolo T. (1990) Decreased dopamine in the retinas of patients with Parkinson's disease. Invest. Ophthalmol. Vis. Sci. 31, 2473-2475.
26. He L., Dinger B., Sanders K., Hoidal J., Obeso A., Stensaas L., Fidone S. and Gonzalez C. (2005) Effect of p47phox gene deletion on ROS production and oxygen sensing in mouse carotid body chemoreceptor cells. Am. J. Physiol. Lung Cell Mol. Physiol. 289, L916-L924.
27. Heath D. and Smith P. (1991) Histological changes associated with ageing of the adult carotid body, in Diseases of the Human Carotid Body. (Heath, D. and Smith, P., eds), pp. 25-22. Springer-Verlag, London.
28. Honda Y. (1985) Role of carotid chemoreceptors in control of breathing at rest and in exercise: studies on human subjects with bilateral carotid body resection. Jpn J. Physiol. 35, 535-544.
29. Hurst G., Heath D. and Smith P. (1985) Histological changes associated with ageing of the human carotid body. J. Pathol. 147, 181-187.
30. Janssens J. P., Pache J. C. and Nicod L. P. (1999) Physiological changes in respiratory function associated with ageing. Eur. Respir J. 13, 197-205.
31. Knapowski J., Wieczorowska-Tobis K. and Witowski J. (2002) Pathophysiology of ageing. J. Physiol. Pharmacol. 53, 135-146.
32. Lahiri S., Roy A., Baby S. M., Hoshi T., Semenza G. L. and Prabhakar N. R. (2005) Oxygen sensing in the body. Prog. Biophys. Mol. Biol. (published online ahead of print).
33. Loeschcke H. H. (1974) Central nervous chemoreceptors, in Respiratory Physiology (Widdicombe, J. G., ed.), pp. 167-196. Butterworths, London.
34. Maxwell G., Crompton S. and Smyth C. (1985) The effect of dopamine upon oxidative metabolism of brown fat adipocytes. Eur. J. Pharmacol. 116, 293-297.
35. McDonald D. M. (1981) Peripheral chemoreceptors. Structure-function relationships of the carotid body, in Regulation of Breathing (Hornbein, T. F., ed.), pp. 105-319. Marcel Dekker, New York.
36. Muhlberg W. and Platt D. (1999) Age-dependent changes of the kidneys: pharmacological implications. Gerontology 45, 243-253.
37. Mukai S., Gagnon M., Iloputaife I., Hamner J. W. and Lipsitz L. A. (2003) Effect of systolic blood pressure and carotid stiffness on baroreflex gain in elderly subjects. J. Gerontol. A Biol. Sci. Med. Sci. 58, 626-630.
38. 2+ channels in stimulus-evoked catecholamine release from chemoreceptor cells of the carotid body. Neuroscience 47, 463-472.
39. Obeso A., Rocher A., Herreros B. and Gonzalez C. (1997) Oxygen consumption and energy metabolism in the carotid body, in The Carotid Body Chemoreceptors (Gonzalez, C., ed.), pp. 28-43.Springer-Verlag, Berlin, Germany.
40. Onodera H., Okabe S., Kikuchi Y., Tsuda T. and Itoyama Y. (2000) Impaired chemosensitivity and perception of dyspnoea in Parkinson's disease. Lancet 356, 739-740.
41. Partanen M., Linnoila I., Hervonent A. and Rapoport S. I. (1984) The effect of aging on extra-adrenal catecholamine storing cells of the rat. Neurobiol. Aging 5, 105-110.
42. Perez-Garcia M. T., Almaraz L. and Gonzalez C. (1990) Effects of different types of stimulation on cyclic AMP content in the rabbit carotid body: functional significance. J. Neurochem. 55, 1287-1293.
43. Phillipson E. A. and Kozar L. F. (1993) Effect of aging on metabolic respiratory control in sleeping dogs. Am. Rev. Respir. Dis. 147, 1521-1525.
44. Pokorsky M., Walski M., Dymecka A. and Marczak M. (2004) The aging carotid body. J. Physiol. Pharmacol. 55, 107-113.
45. Prieto-Lloret J., Caceres A. I., Obeso A. et al. (2004) Ventilatory responses and carotid body function in adult rats perinatally exposed to hyperoxia. J. Physiol. 554, 126-144.
46. Rigual R., Gonzalez E., Gonzalez C. and Fidone S. (1986) Synthesis and release of catecholamines by the cat carotid body in vitro: effects of hypoxic stimulation. Brain Res. 374, 101-109.
47. 2 stimulation of the cat carotid body. J. Physiol. 433, 519-531.
48. Rigual R., Rico A. J., Prieto-Lloret J., de Felipe C., Gonzalez C. and Donnelly D. F. (2002) Chemoreceptor activity is normal in mice lacking the NK1 receptor. Eur. J. Neurosci. 16, 2078-2084.
49. Rocher A., Geijo-Barrientos E., Caceres A. I., Rigual R., Gonzalez C. and Almaraz L. (2005) Role of voltage-dependent calcium channels in stimulus-secretion coupling in rabbit carotid body chemoreceptor cells. J. Physiol. 562, 407-420.
50. Sato A., Sato Y. and Uchida S. (2002) Regulation of cerebral cortical blood flow by the basal forebrain cholinergic fibers and aging. Auton. Neurosci. 96, 13-19.
51. Serot J. M., Bene M. C. and Faure G. C. (2003) Choroid plexus, aging of the brain, and Alzheimer's disease. Front. Biosci. 8, 515-521.
52. Sorbini C. A., Grassi V., Solinas E. and Muiesan G. (1968) Arterial oxygen tension in relation to age in healthy subjects. Respiration 25, 3-13.
53. Soulage C., Pequignot J. M. and Perrin D. (2004) Breathing pattern and hypoxic sensitivity during ageing in a new model of obesity-resistant rat. Respir. Physiol. Neurobiol. 144, 45-57.
54. Timiras P. S. (1972) Development Physiology and Aging, pp. 408-461. Macmillan Co., New York.
55. Vicario I., Rigual R., Obeso A. and Gonzalez C. (2000) Characterization of the synthesis and release of catecholamine in the rat carotid body in vitro. Am. J. Physiol. Cell Physiol. 278, C490-C499.
56. Zapata P. (1997) Chemosensory activity in the carotid nerve: effects of pharmacological agents, in The Carotid Body Chemoreceptors (C. González, ed.), pp. 119-146. Springer-Verlag, Heidelberg, Germany.