-
2
-
-
0029098184
-
Biology and therapy of pediatric rhabdomyosarcoma
-
Pappo AS, Shapiro DN, Crist WM, Maurer HM: Biology and therapy of pediatric rhabdomyosarcoma. J. Clin. Oncol. 13, 2123-2139 (1995).
-
(1995)
J. Clin. Oncol.
, vol.13
, pp. 2123-2139
-
-
Pappo, A.S.1
Shapiro, D.N.2
Crist, W.M.3
Maurer, H.M.4
-
3
-
-
0035876634
-
Intergroup rhabdomyosarcoma study-IV: Results for patients with nonmetastatic disease
-
Crist WM, Anderson JR, Meza JL et al.: Intergroup rhabdomyosarcoma study-IV: results for patients with nonmetastatic disease. J. Clin. Oncol. 19, 3091-3102 (2001).
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 3091-3102
-
-
Crist, W.M.1
Anderson, J.R.2
Meza, J.L.3
-
4
-
-
18744413524
-
Prognostic factors and clinical outcomes in children and adolescents with metastatic rhabdomyosarcoma - A report from the Intergroup Rhabdomyosarcoma Study IV
-
Breneman JC, Lyden E, Pappo AS et al.: Prognostic factors and clinical outcomes in children and adolescents with metastatic rhabdomyosarcoma - a report from the Intergroup Rhabdomyosarcoma Study IV. J. Clin. Oncol. 21, 78-84 (2003).
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 78-84
-
-
Breneman, J.C.1
Lyden, E.2
Pappo, A.S.3
-
5
-
-
16544387908
-
European intergroup studies (MMT4-89 and MMT4-91) on childhood metastatic rhabdomyosarcoma: Final results and analysis of prognostic factors
-
Carli M, Colombatti R, Oberlin O et al.: European intergroup studies (MMT4-89 and MMT4-91) on childhood metastatic rhabdomyosarcoma: final results and analysis of prognostic factors. J. Clin. Oncol. 22, 4735-4742 (2004).
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 4735-4742
-
-
Carli, M.1
Colombatti, R.2
Oberlin, O.3
-
6
-
-
0034918470
-
Role of high-dose chemotherapy with hematopoietic stem cell rescue in the treatment of metastatic or recurrent rhabdomyosarcoma
-
Weigel BJ, Breitfeld PP, Hawkins D. Crist WM, Baker KS: Role of high-dose chemotherapy with hematopoietic stem cell rescue in the treatment of metastatic or recurrent rhabdomyosarcoma. J. Pediatr. Hematol. Oncol. 23, 272-276 (2001).
-
(2001)
J. Pediatr. Hematol. Oncol.
, vol.23
, pp. 272-276
-
-
Weigel, B.J.1
Breitfeld, P.P.2
Hawkins, D.3
Crist, W.M.4
Baker, K.S.5
-
7
-
-
4644335909
-
Cyclophosphamide dose intensification during induction therapy for intermediate-risk pediatric rhabdomyosarcoma is feasible but does not improve outcome: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group
-
Spunt SL, Smith LM, Ruymann FB et al.: Cyclophosphamide dose intensification during induction therapy for intermediate-risk pediatric rhabdomyosarcoma is feasible but does not improve outcome: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group. Clin. Cancer Res. 10. 6072-6079 (2004).
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 6072-6079
-
-
Spunt, S.L.1
Smith, L.M.2
Ruymann, F.B.3
-
8
-
-
0035155499
-
Up-front window trial of topotecan in previously untreated children and adolescents with metastatic rhabdomyosarcoma: An intergroup rhabdomyosarcoma study
-
Pappo AS, Lyden E, Breneman J et al.: Up-front window trial of topotecan in previously untreated children and adolescents with metastatic rhabdomyosarcoma: an intergroup rhabdomyosarcoma study. J. Clin. Oncol. 19, 213-219 (2001).
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 213-219
-
-
Pappo, A.S.1
Lyden, E.2
Breneman, J.3
-
9
-
-
0036896670
-
Testing of new agents in childhood cancer preclinical models: Meeting summary
-
Houghton PJ, Adamson PC, Blaney S et al.: Testing of new agents in childhood cancer preclinical models: meeting summary. Clin. Cancer Res. 8, 3646-3657 (2002).
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 3646-3657
-
-
Houghton, P.J.1
Adamson, P.C.2
Blaney, S.3
-
10
-
-
0031742751
-
Extending principles learned in model systems to clinical trials design
-
Houghton PJ, Stewart CF, Thompson J, Santana VM, Furman WL, Friedman HS: Extending principles learned in model systems to clinical trials design. Oncology 12, 84-93 (1998).
-
(1998)
Oncology
, vol.12
, pp. 84-93
-
-
Houghton, P.J.1
Stewart, C.F.2
Thompson, J.3
Santana, V.M.4
Furman, W.L.5
Friedman, H.S.6
-
11
-
-
0033039308
-
Direct translation of a protracted irinotecan schedule from a xenograft model to a Phase I trial in children
-
Furman WL, Stewart CF, Poquette CA et al.: Direct translation of a protracted irinotecan schedule from a xenograft model to a Phase I trial in children. J. Clin. Oncol. 17, 1815-1824 (1999).
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 1815-1824
-
-
Furman, W.L.1
Stewart, C.F.2
Poquette, C.A.3
-
12
-
-
0023257034
-
Characterization of cell lines derived from xenografts of childhood rhabdomyosarcoma
-
Hazelton BJ, Houghton JA, Parham DM et al.: Characterization of cell lines derived from xenografts of childhood rhabdomyosarcoma. Cancer Res. 47. 4501-4507 (1987).
-
(1987)
Cancer Res.
, vol.47
, pp. 4501-4507
-
-
Hazelton, B.J.1
Houghton, J.A.2
Parham, D.M.3
-
13
-
-
0021263850
-
Childhood rhabdomyosarcoma xenografts: Responses to DNA-interacting agents and agents used in current clinical therapy
-
Houghton JA, Cook RL, Lutz PJ, Houghton PJ: Childhood rhabdomyosarcoma xenografts: responses to DNA-interacting agents and agents used in current clinical therapy. Eur. J. Cancer Clin. Oncol. 20, 955-960 (1984).
-
(1984)
Eur. J. Cancer Clin. Oncol.
, vol.20
, pp. 955-960
-
-
Houghton, J.A.1
Cook, R.L.2
Lutz, P.J.3
Houghton, P.J.4
-
14
-
-
33750085634
-
Irinotecan (CPT-11) is active against pediatric rhabdomyosarcoma (RMS): A Phase II window trial from the Soft Tissue Sarcoma Committee (STS) of the Children's Oncology Group (COG)
-
Presented at: the American Society Clinical Oncology. Orlando, FL. USA 18-21 May
-
Pappo AS, Lyden E, Breitfeld P et al.: Irinotecan (CPT-11) is active against pediatric rhabdomyosarcoma (RMS): a Phase II window trial from the Soft Tissue Sarcoma Committee (STS) of the Children's Oncology Group (COG). Presented at: the American Society Clinical Oncology. Orlando, FL. USA 18-21 May 2002.
-
(2002)
-
-
Pappo, A.S.1
Lyden, E.2
Breitfeld, P.3
-
15
-
-
0033800708
-
Clinical use of topoisomerase I inhibitors in anticancer treatment
-
Rodriguez-Galindo C, Radomski K, Stewart CF, Furman W, Santana VM, Houghton PJ: Clinical use of topoisomerase I inhibitors in anticancer treatment. Med. Pediatr. Oncol. 35, 385-402 (2000).
-
(2000)
Med. Pediatr. Oncol.
, vol.35
, pp. 385-402
-
-
Rodriguez-Galindo, C.1
Radomski, K.2
Stewart, C.F.3
Furman, W.4
Santana, V.M.5
Houghton, P.J.6
-
16
-
-
0029116438
-
Efficacy of topoisomerase I inhibitors topotecan and irinotecan administered at low dose levels in protracted schedules to mice bearing xenografts of human tumors
-
Houghton PJ, Cheshire PJ, Hallman JD et al.: Efficacy of topoisomerase I inhibitors topotecan and irinotecan administered at low dose levels in protracted schedules to mice bearing xenografts of human tumors. Cancer Chemother. Pharmacol. 36, 393-403 (1995).
-
(1995)
Cancer Chemother. Pharmacol.
, vol.36
, pp. 393-403
-
-
Houghton, P.J.1
Cheshire, P.J.2
Hallman, J.D.3
-
17
-
-
2342487374
-
Efficacy of topotecan and cyclophosphamide given in a Phase II window trial in children with newly diagnosed metastatic rhabdomyo-sarcoma: A Children's Oncology Group Study
-
Walterhouse DO, Lyden ER, Breitfeld PP, Qualman SJ. Wharam MD, Meyer WH: Efficacy of topotecan and cyclophosphamide given in a Phase II window trial in children with newly diagnosed metastatic rhabdomyo-sarcoma: a Children's Oncology Group Study. J. Clin. Oncol. 22, 1398-1403 (2004).
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 1398-1403
-
-
Walterhouse, D.O.1
Lyden, E.R.2
Breitfeld, P.P.3
Qualman, S.J.4
Wharam M.D. Meyer, W.H.5
-
18
-
-
0027407637
-
Pediatric Phase I trial and pharmacokinetic study of topotecan administered as a 24-hour continuous infusion
-
Blaney SM, Balis FM. Cole DE et al.: Pediatric Phase I trial and pharmacokinetic study of topotecan administered as a 24-hour continuous infusion. Cancer Res. 53, 1032-1036 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 1032-1036
-
-
Blaney, S.M.1
Balis, F.M.2
Cole, D.E.3
-
19
-
-
0031939569
-
Phase II trial of topotecan administered as 72-hour continuous infusion in children with refractory solid tumors: A collaborative Pediatric Branch National Cancer Institute and Children's Cancer Group Study
-
Blaney SM, Needle MN, Gillespie A et al.: Phase II trial of topotecan administered as 72-hour continuous infusion in children with refractory solid tumors: a collaborative Pediatric Branch National Cancer Institute and Children's Cancer Group Study. Clin. Cancer Res. 4, 357-360 (1998).
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 357-360
-
-
Blaney, S.M.1
Needle, M.N.2
Gillespie, A.3
-
20
-
-
8944222113
-
Phase II evaluation of topotecan for pediatric central nervous system tumors
-
Blaney SM, Phillips PC, Packer RJ et al.: Phase II evaluation of topotecan for pediatric central nervous system tumors. Cancer 78, 527-531 (1996).
-
(1996)
Cancer
, vol.78
, pp. 527-531
-
-
Blaney, S.M.1
Phillips, P.C.2
Packer, R.J.3
-
21
-
-
33749178251
-
Topotecan by 21-day continuous infusion in children with relapsed or refractory solid tumors: A Children's Oncology Group study
-
(Epub ahead of print)
-
Hawkins DS, Bradfield S, Whitlock JA et al.: Topotecan by 21-day continuous infusion in children with relapsed or refractory solid tumors: a Children's Oncology Group study. Pediatr. Blood Cancer (2006) (Epub ahead of print).
-
(2006)
Pediatr. Blood Cancer
-
-
Hawkins, D.S.1
Bradfield, S.2
Whitlock, J.A.3
-
22
-
-
0031759531
-
Topotecan in pediatric patients with recurrent and progressive solid tumors: A Pediatric Oncology Group Phase II study
-
Nitschke R, Parkhurst J, Sullivan J, Harris MB, Bernstein M, Pratt C: Topotecan in pediatric patients with recurrent and progressive solid tumors: a Pediatric Oncology Group Phase II study. J. Pediatr. Hematol. Oncol. 20, 315-318 (1998).
-
(1998)
J. Pediatr. Hematol. Oncol.
, vol.20
, pp. 315-318
-
-
Nitschke, R.1
Parkhurst, J.2
Sullivan, J.3
Harris, M.B.4
Bernstein, M.5
Pratt, C.6
-
23
-
-
0035424844
-
Cyclophosphamide plus topotecan in children with recurrent or refractory solid tumors: A Pediatric Oncology Group Phase II study
-
Saylors RL, Stine KC, Sullivan J et al.: Cyclophosphamide plus topotecan in children with recurrent or refractory solid tumors: a Pediatric Oncology Group Phase II study. J. Clin. Oncol. 19, 3463-3469 (2001).
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 3463-3469
-
-
Saylors, R.L.1
Stine, K.C.2
Sullivan, J.3
-
24
-
-
0032758266
-
Synergy of topotecan in combination with vincristine for treatment of pediatric solid tumor xenografts
-
Thompson J, George EO, Poquette CA et al.: Synergy of topotecan in combination with vincristine for treatment of pediatric solid tumor xenografts. Clin. Cancer Res. 5, 3617-3631 (1999).
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 3617-3631
-
-
Thompson, J.1
George, E.O.2
Poquette, C.A.3
-
25
-
-
33644841966
-
Cefixime allows greater dose escalation of oral irinotecan: A Phase I study in pediatric patients with refractory solid tumors
-
Furman WL, Crews KR, Billups C et al.: Cefixime allows greater dose escalation of oral irinotecan: a Phase I study in pediatric patients with refractory solid tumors. J. Clin. Oncol. 24, 563-570 (2006).
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 563-570
-
-
Furman, W.L.1
Crews, K.R.2
Billups, C.3
-
26
-
-
0037096950
-
Vinorelbine in previously treated advanced childhood sarcomas: Evidence of activity in rhabdomyosarcoma
-
Casanova M, Ferrari A, Spreafìco, F et al.: Vinorelbine in previously treated advanced childhood sarcomas: evidence of activity in rhabdomyosarcoma. Cancer 94, 3263-3268 (2002).
-
(2002)
Cancer
, vol.94
, pp. 3263-3268
-
-
Casanova, M.1
Ferrari, A.2
Spreafìco, F.3
-
27
-
-
33750039234
-
Phase II evaluation of vinorelbine in recurrent pediatric malignancies
-
Presented at: the American Society Clinical Oncology. Orlando, FL, USA 18-21 May
-
Kuttesch JF, Krallo MD, Bleyer WA, Reaman GH: Phase II evaluation of vinorelbine in recurrent pediatric malignancies. Presented at: the American Society Clinical Oncology. Orlando, FL, USA 18-21 May 2005.
-
(2005)
-
-
Kuttesch, J.F.1
Krallo, M.D.2
Bleyer, W.A.3
Reaman, G.H.4
-
28
-
-
4844220366
-
Vinorelbine and low-dose cyclophosphamide in the treatment of pediatric sarcomas: Pilot study for the upcoming European Rhabdomyosarcoma Protocol
-
Casanova M, Ferrari A, Bisogno G et al.: Vinorelbine and low-dose cyclophosphamide in the treatment of pediatric sarcomas: pilot study for the upcoming European Rhabdomyosarcoma Protocol. Cancer 101, 1664-1671 (2004).
-
(2004)
Cancer
, vol.101
, pp. 1664-1671
-
-
Casanova, M.1
Ferrari, A.2
Bisogno, G.3
-
29
-
-
26444507974
-
In vivo evaluation of ixabepilone (BMS247550), a novel epothilone B derivative against pediatric cancer models
-
Peterson JK, Tucker C, Favours E et al.: In vivo evaluation of ixabepilone (BMS247550), a novel epothilone B derivative against pediatric cancer models. Clin. Cancer Res. 11, 6950-6958 (2005).
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 6950-6958
-
-
Peterson, J.K.1
Tucker, C.2
Favours, E.3
-
30
-
-
2342559981
-
The TOR pathway: A target for cancer therapy
-
Bjornsti MA, Houghton PJ: The TOR pathway: a target for cancer therapy. Nat. Rev. Cancer 4, 335-348 (2004).
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 335-348
-
-
Bjornsti, M.A.1
Houghton, P.J.2
-
31
-
-
0033557578
-
Rapamycin causes poorly reversible inhibition of mTOR and induces p53-independent apoptosis in human rhabdomyosarcoma cells
-
Hosoi H, Dilling MB, Shikata T et al.: Rapamycin causes poorly reversible inhibition of mTOR and induces p53-independent apoptosis in human rhabdomyosarcoma cells. Cancer Res. 59, 886-894 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 886-894
-
-
Hosoi, H.1
Dilling, M.B.2
Shikata, T.3
-
32
-
-
27644534999
-
Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate1/phosphatidylinositol 3-kinase cascade
-
Shi Y, Yan H, Frost P, Gera J, Lichtenstein A: Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate1/phosphatidylinositol 3-kinase cascade. Mol. Cancer Ther. 4, 1533-1540 (2005).
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 1533-1540
-
-
Shi, Y.1
Yan, H.2
Frost, P.3
Gera, J.4
Lichtenstein, A.5
-
33
-
-
0032794460
-
Prognostic factors for children and adolescents with surgically resected nonrhabdomyosarcoma soft tissue sarcoma: An analysis of 121 patients treated at St Jude Children's Research Hospital
-
Spunt SL, Poquette CA, Hurt YS et al.: Prognostic factors for children and adolescents with surgically resected nonrhabdomyosarcoma soft tissue sarcoma: an analysis of 121 patients treated at St Jude Children's Research Hospital. J. Clin. Oncol. 17, 3697-3705 (1999).
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 3697-3705
-
-
Spunt, S.L.1
Poquette, C.A.2
Hurt, Y.S.3
-
34
-
-
0032927813
-
Role of adjuvant chemotherapy in the treatment of surgically resected pediatric nonrhabdomyosarcomatous soft tissue sarcomas: A Pediatric Oncology Group study
-
Pratt CB, Pappo AS, Gieser P et al.: Role of adjuvant chemotherapy in the treatment of surgically resected pediatric nonrhabdomyosarcomatous soft tissue sarcomas: a Pediatric Oncology Group study. J. Clin. Oncol. 17, 1219 (1999).
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 1219
-
-
Pratt, C.B.1
Pappo, A.S.2
Gieser, P.3
-
35
-
-
23044441741
-
Phase II trial of neoadjuvant vincristine ifosfamide and doxorubicin with granulocyte colony-stimulating factor support in children and adolescents with advanced-stage nonrhabdomyosarcomatous soft tissue sarcomas: A Pediatric Oncology Group study
-
Pappo AS, Devidas M, Jenkins J et al.: Phase II trial of neoadjuvant vincristine ifosfamide and doxorubicin with granulocyte colony-stimulating factor support in children and adolescents with advanced-stage nonrhabdomyosarcomatous soft tissue sarcomas: a Pediatric Oncology Group study. J. Clin. Oncol. 23, 4031-4038 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 4031-4038
-
-
Pappo, A.S.1
Devidas, M.2
Jenkins, J.3
-
36
-
-
17944395368
-
Treatment of unresectable or metastatic pediatric soft tissue sarcomas with surgery irradiation and chemotherapy: A Pediatric Oncology Group study
-
Pratt CB, Maurer HM, Gieser P et al.: Treatment of unresectable or metastatic pediatric soft tissue sarcomas with surgery irradiation and chemotherapy: a Pediatric Oncology Group study. Med. Pediatr. Oncol. 30, 201-209 (1998).
-
(1998)
Med. Pediatr. Oncol.
, vol.30
, pp. 201-209
-
-
Pratt, C.B.1
Maurer, H.M.2
Gieser, P.3
-
37
-
-
0036682012
-
Clinical features and outcome of initially unresected nonmetastatic pediatric nonrhabdomyosarcoma soft tissue sarcoma
-
Spunt SL, Hill DA, Motosue AM et al.: Clinical features and outcome of initially unresected nonmetastatic pediatric nonrhabdomyosarcoma soft tissue sarcoma. J. Clin. Oncol. 20, 3225-3235 (2002).
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 3225-3235
-
-
Spunt, S.L.1
Hill, D.A.2
Motosue, A.M.3
-
38
-
-
33644667931
-
Pediatric malignant peripheral nerve sheath tumor: The Italian and German soft tissue sarcoma cooperative group
-
Carli M, Ferrari A, Mattke A et al.: Pediatric malignant peripheral nerve sheath tumor: the Italian and German soft tissue sarcoma cooperative group. J. Clin. Oncol. 23, 8422-8430 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 8422-8430
-
-
Carli, M.1
Ferrari, A.2
Mattke, A.3
-
40
-
-
23044452536
-
Phase II study of G3139, a Bc1-2 antisense oligonucleotide in combination with dexamethasone and thalidomide in relapsed multiple myeloma patients
-
Badros AZ, Goloubeva O, Rapoport AP et al.: Phase II study of G3139, a Bc1-2 antisense oligonucleotide in combination with dexamethasone and thalidomide in relapsed multiple myeloma patients. J. Clin. Oncol. 23, 4089-4099 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 4089-4099
-
-
Badros, A.Z.1
Goloubeva, O.2
Rapoport, A.P.3
-
41
-
-
33645736984
-
G3139 antisense oligonucleotide directed against antiapoptotic Bc1-2 enhances doxorubicin cytotoxicity in the FU-SY-1 synovial sarcoma cell line
-
Joyner DE, Albritton KH, Bastar JD, Randall RL: G3139 antisense oligonucleotide directed against antiapoptotic Bc1-2 enhances doxorubicin cytotoxicity in the FU-SY-1 synovial sarcoma cell line. J. Orthop. Res. 24, 474-480 (2006).
-
(2006)
J. Orthop. Res.
, vol.24
, pp. 474-480
-
-
Joyner, D.E.1
Albritton, K.H.2
Bastar, J.D.3
Randall, R.L.4
-
42
-
-
0036840271
-
Expression profiling of synovial sarcoma by cDNA microarrays: Association of ERBB2, IGFBP2, and ELF3 with epithelial differentiation
-
Altander SV, Illei PB, Chen Y et al.: Expression profiling of synovial sarcoma by cDNA microarrays: association of ERBB2, IGFBP2. and ELF3 with epithelial differentiation. Am. J. Pathol. 161, 1587-1595 (2002).
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 1587-1595
-
-
Altander, S.V.1
Illei, P.B.2
Chen, Y.3
-
43
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, BD, Sordella R, Gurubhagavatula S et al.: Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N. Engl. J. Med. 350, 2129-2139 (2004).
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Lynch, B.D.2
Sordella, R.3
Gurubhagavatula, S.4
-
44
-
-
33645301012
-
Mutations in the tyrosine kinase domain of the EGFR gene are rare in synovial sarcoma
-
Bode B, Frigerio S, Behnke S et al.: Mutations in the tyrosine kinase domain of the EGFR gene are rare in synovial sarcoma. Mod. Pathol. 19, 541-547 (2006).
-
(2006)
Mod. Pathol.
, vol.19
, pp. 541-547
-
-
Bode, B.1
Frigerio, S.2
Behnke, S.3
-
45
-
-
24944519394
-
Phase I and pharmacokinetic study of gefitinib in children with refractory solid tumors: A Children's Oncology Group study
-
Daw NC, Furman WL, Stewart CF et al.: Phase I and pharmacokinetic study of gefitinib in children with refractory solid tumors: a Children's Oncology Group study. J. Clin. Oncol. 23, 6172-6180 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 6172-6180
-
-
Daw, N.C.1
Furman, W.L.2
Stewart, C.F.3
-
46
-
-
33645061486
-
Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues
-
Miller SJ. Rangwala F, Williams J et al.: Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues. Cancer Res. 66, 2584-2591 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 2584-2591
-
-
Miller, S.J.1
Rangwala, F.2
Williams, J.3
-
47
-
-
19944430338
-
Role for the epidermal growth factor receptor in neurofibromatosis-related peripheral nerve tumorigenesis
-
Ling BC, Wu J. Miller SJ et al.: Role for the epidermal growth factor receptor in neurofibromatosis-related peripheral nerve tumorigenesis. Cancer Cell 7, 65-75 (2005).
-
(2005)
Cancer Cell
, vol.7
, pp. 65-75
-
-
Ling, B.C.1
Wu, J.2
Miller, S.J.3
-
48
-
-
0041629450
-
Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer
-
Mendelsohn J, Baselga J: Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer. J. Clin. Oncol. 21, 2787-2799 (2003).
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 2787-2799
-
-
Mendelsohn, J.1
Baselga, J.2
-
49
-
-
0032704708
-
Ras protein farnesyltransferase: A strategic target for anticancer therapeutic development
-
Rowinsky EK, Windle JJ, Von Hoff DD: Ras protein farnesyltransferase: a strategic target for anticancer therapeutic development. J. Clin. Oncol. 17, 3631-3652 (1999).
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 3631-3652
-
-
Rowinsky, E.K.1
Windle, J.J.2
Von Hoff, D.D.3
-
50
-
-
33644838556
-
Phase I trial and pharmacokinetic study of the farnesyltransferase inhibitor tipifarnib in children with refractory solid tumors or neurofibromatosis Type I and plexiform neurofibromas
-
Widemann BC, Salzer WL, Arceci RJ et al.: Phase I trial and pharmacokinetic study of the farnesyltransferase inhibitor tipifarnib in children with refractory solid tumors or neurofibromatosis Type I and plexiform neurofibromas. J. Clin. Oncol. 24, 507-516 (2006).
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 507-516
-
-
Widemann, B.C.1
Salzer, W.L.2
Arceci, R.J.3
-
51
-
-
0033566150
-
Ecteinascidin-743: A minor groove alkylator that bends DNA toward the major groove
-
Zewail-Foote M, Hurley LH: Ecteinascidin-743: a minor groove alkylator that bends DNA toward the major groove. J. Med. Chem. 42, 2493-2497 (1999).
-
(1999)
J. Med. Chem.
, vol.42
, pp. 2493-2497
-
-
Zewail-Foote, M.1
Hurley, L.H.2
-
52
-
-
0034612344
-
Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743
-
Minuzzo M, Marchini S. Broggini M, Faircloth G, D'Incalci M, Mantovani R: Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743. Proc. Natl Acad. Sci. US4 97, 6780-6784 (2000).
-
(2000)
Proc. Natl Acad. Sci. US4
, vol.97
, pp. 6780-6784
-
-
Minuzzo, M.1
Marchini, S.2
Broggini, M.3
Faircloth, G.4
D'Incalci, M.5
Mantovani, R.6
-
53
-
-
0034612352
-
Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation
-
Jin S, Gorfajn B. Faircloth G, Scotto KW: Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation. Proc. Natl Acad. Sci. USA 97, 6775-6779 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 6775-6779
-
-
Jin, S.1
Gorfajn, B.2
Faircloth, G.3
Scotto, K.W.4
-
54
-
-
20044372153
-
Phase II study of ET-743 in advanced soft tissue sarcomas: A European Organisation for the Research and Treatment of Cancer (EORTC) soft tissue and bone sarcoma group trial
-
Le Cesne A, Blay JY, Judson I et al.: Phase II study of ET-743 in advanced soft tissue sarcomas: a European Organisation for the Research and Treatment of Cancer (EORTC) soft tissue and bone sarcoma group trial. J. Clin. Oncol. 23, 576-584 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 576-584
-
-
Le Cesne, A.1
Blay, J.Y.2
Judson, I.3
-
55
-
-
1542398698
-
Phase II study of ecteinascidin-743 in advanced pretreated soft tissue sarcoma patients
-
Yovine A, Riofrio M, Blay JY et al.: Phase II study of ecteinascidin-743 in advanced pretreated soft tissue sarcoma patients. J. Clin. Oncol. 22, 890-899 (2004).
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 890-899
-
-
Yovine, A.1
Riofrio, M.2
Blay, J.Y.3
-
56
-
-
2342461682
-
Phase II and pharmacokinetic study of ecteinascidin-743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy
-
Garcia-Carbonero R, Supko JG, Manola J et al.: Phase II and pharmacokinetic study of ecteinascidin-743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy. J. Clin. Oncol. 22, 1480-1490 (2004).
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 1480-1490
-
-
Garcia-Carbonero, R.1
Supko, J.G.2
Manola, J.3
-
57
-
-
33750090138
-
Tumor control and objective responses: Single center experience with ecteinascidin-743 (ET-743, Yondelis), an active compound for the treatment of patients with advanced soft tissue and bone sarcomas
-
Presented at: the American Society Clinical Oncology. Orlando, FL, USA 18-21 May
-
Schoffski P, Huygh G, Clement P et al.: Tumor control and objective responses: single center experience with ecteinascidin-743 (ET-743, Yondelis), an active compound for the treatment of patients with advanced soft tissue and bone sarcomas. Presented at: the American Society Clinical Oncology,. Orlando, FL, USA 18-21 May 2005.
-
(2005)
-
-
Schoffski, P.1
Huygh, G.2
Clement, P.3
-
58
-
-
0036189675
-
Progression-free rate as the principal end-point for Phase II trials in soft-tissue sarcomas
-
Van Glabbeke M, Verweij J, Judson I, Nielsen OS: Progression-free rate as the principal end-point for Phase II trials in soft-tissue sarcomas. Eur. J. Cancer 38, 543-549 (2002).
-
(2002)
Eur. J. Cancer
, vol.38
, pp. 543-549
-
-
Van Glabbeke, M.1
Verweij, J.2
Judson, I.3
Nielsen, O.S.4
-
59
-
-
24944518102
-
Ecteinascidin-743 (ET-743): Early test or effective treatment in soft tissue sarcomas?
-
Verweij J: Ecteinascidin-743 (ET-743): early test or effective treatment in soft tissue sarcomas? J. Clin. Oncol. 23, 5420-5423 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 5420-5423
-
-
Verweij, J.1
-
60
-
-
24944460785
-
Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: Multicenter Phase II and pharmacokinetic study
-
Garcia-Carbonero R, Supko JG, Maki RG et al.: Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: multicenter Phase II and pharmacokinetic study. J. Clin. Oncol. 23, 5484-5492 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 5484-5492
-
-
Garcia-Carbonero, R.1
Supko, J.G.2
Maki, R.G.3
-
61
-
-
19944426087
-
A Phase I and pharmacokinetic study of ecteinascidin-743 (Yondelis) in children with refractory solid tumors
-
A Children's Oncology Group study
-
Lau L, Supko JG, Blaney S et al.: A Phase I and pharmacokinetic study of ecteinascidin-743 (Yondelis) in children with refractory solid tumors. A Children's Oncology Group study. Clin. Cancer Res. 11, 672-677 (2005).
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 672-677
-
-
Lau, L.1
Supko, J.G.2
Blaney, S.3
-
62
-
-
1942438028
-
Microtubules as a target for anticancer drugs
-
Jordan MA, Wilson L: Microtubules as a target for anticancer drugs. Nat. Rev. Cancer 4, 253-265 (2004).
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 253-265
-
-
Jordan, M.A.1
Wilson, L.2
-
63
-
-
0026324313
-
Action of 2′,2′-difluorodeoxycytidine on DNA synthesis
-
Huang P, Chubb S, Hertel LW, Grindey GB, Plunkett W: Action of 2′,2′-difluorodeoxycytidine on DNA synthesis. Cancer Res. 51, 6110-6117 (1991).
-
(1991)
Cancer Res.
, vol.51
, pp. 6110-6117
-
-
Huang, P.1
Chubb, S.2
Hertel, L.W.3
Grindey, G.B.4
Plunkett, W.5
-
64
-
-
0030895964
-
Phase I trial of docetaxel administered as a 1-hour infusion in children with refractory solid tumors: A collaborative pediatric branch National Cancer Institute and Children's Cancer Group trial
-
Blaney SM, Seibel NL, O'Brien M et al.: Phase I trial of docetaxel administered as a 1-hour infusion in children with refractory solid tumors: a collaborative pediatric branch National Cancer Institute and Children's Cancer Group trial. J. Clin. Oncol. 15, 1538-1543 (1997).
-
(1997)
J. Clin. Oncol.
, vol.15
, pp. 1538-1543
-
-
Blaney, S.M.1
Seibel, N.L.2
O'Brien, M.3
-
65
-
-
0032962180
-
Phase I trial of docetaxel with filgrastim support in pediatric patients with refractory solid tumors: A collaborative Pediatric Oncology Branch National Cancer Institute and Children's Cancer Group trial
-
Seibel NL, Blaney SM, O'Brien M et al.: Phase I trial of docetaxel with filgrastim support in pediatric patients with refractory solid tumors: a collaborative Pediatric Oncology Branch National Cancer Institute and Children's Cancer Group trial. Clin. Cancer Res. 5, 733-737 (1999).
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 733-737
-
-
Seibel, N.L.1
Blaney, S.M.2
O'Brien, M.3
-
66
-
-
33646045624
-
Phase II investigation of docetaxel in pediatric patients with recurrent solid tumors: A report from the Children's Oncology Group
-
(Epub ahead of print)
-
Zwerdling T, Krailo M, Monteleone P et al.: Phase II investigation of docetaxel in pediatric patients with recurrent solid tumors: a report from the Children's Oncology Group. Cancer (2006) (Epub ahead of print).
-
(2006)
Cancer
-
-
Zwerdling, T.1
Krailo, M.2
Monteleone, P.3
-
67
-
-
2942700264
-
Phase I trial and pharmacokinetics of gemcitabine in children with advanced solid tumors
-
Reid JM, Qu W, Safgren SL et al.: Phase I trial and pharmacokinetics of gemcitabine in children with advanced solid tumors. J. Clin. Oncol. 22, 2445-2451 (2004).
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 2445-2451
-
-
Reid, J.M.1
Qu, W.2
Safgren, S.L.3
-
68
-
-
2442635522
-
Laboratory and clinical evidence of synergistic cytotoxicity of sequential treatment with gemcitabine followed by docetaxel in the treatment of sarcoma
-
Leu KM, Ostruszka LJ, Shewach D et al.: Laboratory and clinical evidence of synergistic cytotoxicity of sequential treatment with gemcitabine followed by docetaxel in the treatment of sarcoma. J. Clin. Oncol. 22, 1706-1712 (2004).
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 1706-1712
-
-
Leu, K.M.1
Ostruszka, L.J.2
Shewach, D.3
-
69
-
-
0037096747
-
Gemcitabine and docetaxel in patients with unresectable leiomyosarcoma: Results of a Phase II trial
-
Hensley ML, Maki R, Venkatraman E et al.: Gemcitabine and docetaxel in patients with unresectable leiomyosarcoma: results of a Phase II trial. J. Clin. Oncol. 20, 2824-2831 (2002).
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 2824-2831
-
-
Hensley, M.L.1
Maki, R.2
Venkatraman, E.3
-
70
-
-
0023371142
-
Scheduling of vincristine: Drug accumulation and response of xenografts of childhood rhabdomyosarcoma determined by frequency of administration
-
Houghton JA, Meyer WH, Houghton PJ: Scheduling of vincristine: drug accumulation and response of xenografts of childhood rhabdomyosarcoma determined by frequency of administration. Cancer Treat Rep. 71, 717-721 (1987).
-
(1987)
Cancer Treat Rep.
, vol.71
, pp. 717-721
-
-
Houghton, J.A.1
Meyer, W.H.2
Houghton, P.J.3
-
71
-
-
0021934470
-
Melphalan: A potential new agent in the treatment of childhood rhabdomyosarcoma
-
Houghton JA, Cook RL, Lutz PJ, Houghton PJ: Melphalan: a potential new agent in the treatment of childhood rhabdomyosarcoma. Cancer Treat Rep. 69, 91-96 (1985).
-
(1985)
Cancer Treat Rep.
, vol.69
, pp. 91-96
-
-
Houghton, J.A.1
Cook, R.L.2
Lutz, P.J.3
Houghton, P.J.4
-
72
-
-
31544451582
-
Phase II study of a protracted irinotecan schedule in children with refractory or recurrent soft tissue sarcoma
-
Bisogno G, Riccardi R, Ruggiero A et al.: Phase II study of a protracted irinotecan schedule in children with refractory or recurrent soft tissue sarcoma. Cancer 106, 703-707 (2006).
-
(2006)
Cancer
, vol.106
, pp. 703-707
-
-
Bisogno, G.1
Riccardi, R.2
Ruggiero, A.3
-
73
-
-
2542447480
-
Pediatric Phase I trial and pharmacokinetic study of the platelet-derived growth factor (PDGF) receptor pathway inhibitor SU 101
-
Adamson PC, Blaney SM, Widemann BC et al.: Pediatric Phase I trial and pharmacokinetic study of the platelet-derived growth factor (PDGF) receptor pathway inhibitor SU 101. Cancer Chemother. Pharmacol. 53, 482-488 (2004).
-
(2004)
Cancer Chemother. Pharmacol.
, vol.53
, pp. 482-488
-
-
Adamson, P.C.1
Blaney, S.M.2
Widemann, B.C.3
-
74
-
-
33750059525
-
Phase 2 trial of imatinib mesylate (IM) for treatment or recurrent or refractory pediatric solid tumors: A Children's Oncology Group Study
-
Presented at: the American Society Clinical Oncology. Orlando, FL, USA 18-21 May
-
Bond M, BM, Pappo A, Schultz KR et al.: Phase 2 trial of imatinib mesylate (IM) for treatment or recurrent or refractory pediatric solid tumors: a Children's Oncology Group Study. Presented at: the American Society Clinical Oncology. Orlando, FL, USA 18-21 May 2005.
-
(2005)
-
-
Bond, M.1
Bond, B.M.2
Pappo, A.3
Schultz, K.R.4
-
75
-
-
33750050027
-
A Phase I study of Gefitinib and irinotecan (IRN) in pediatric patients with refractory solid tumors
-
Presented at: the American Society Clinical Oncology. Orlando, FL. USA 18-21 May
-
Furman W, Daw NC, Crews KR et al.: A Phase I study of Gefitinib and irinotecan (IRN) in pediatric patients with refractory solid tumors. Presented at: the American Society Clinical Oncology. Orlando, FL. USA 18-21 May 2005.
-
(2005)
-
-
Furman, W.1
Daw, N.C.2
Crews, K.R.3
-
76
-
-
16544389047
-
Phase I study of the proteasome inhibitor bortezomib in pediatric patients with refractory solid tumors: A Children's Oncology Group study
-
(ADVL0015)
-
Blaney SM, Bernstein M, Neville K et al.: Phase I study of the proteasome inhibitor bortezomib in pediatric patients with refractory solid tumors: a Children's Oncology Group study (ADVL0015). J. Clin. Oncol. 22, 4804-4809 (2004).
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 4804-4809
-
-
Blaney, S.M.1
Bernstein, M.2
Neville, K.3
-
77
-
-
33750088203
-
Pediatric Phase I trial and pharmacokinetic study of p-glycoprotein inhibitor tariquidar in combination with doxorubicin vinorelbine or docetaxel
-
Presented at: the American Society Clinical Oncology. New Orleans, MS, USA May 17-18
-
Fox E, Widemann B, Chen C et al.: Pediatric Phase I trial and pharmacokinetic study of p-glycoprotein inhibitor tariquidar in combination with doxorubicin vinorelbine or docetaxel. Presented at: the American Society Clinical Oncology. New Orleans, MS, USA May 17-18 2004.
-
(2004)
-
-
Fox, E.1
Widemann, B.2
Chen, C.3
-
78
-
-
33750086385
-
A Phase I trial of G3139 (bc1-2 antisense) combined with cytotoxic chemotherapy in relapsed solid tumors
-
A Children's Oncology Group Study. Presented at: the American Society Clinical Oncology. Orlando, FL, USA 18-21 May
-
Rheingold S, Blayney S, Hogarty M et al.: A Phase I trial of G3139 (bc1-2 antisense) combined with cytotoxic chemotherapy in relapsed solid tumors. A Children's Oncology Group Study. Presented at: the American Society Clinical Oncology. Orlando, FL, USA 18-21 May 2005.
-
(2005)
-
-
Rheingold, S.1
Blayney, S.2
Hogarty, M.3
-
79
-
-
33750046973
-
A Phase I stduy of deciabine (DCT) in combination with doxorubicin (DOX) and cyclophosphamide (CTX) in the treatment of relapsed or refractory solid tumors: A Children's Oncology Group Study
-
American Society of Clinical Oncology. Orlando. FL, USA
-
George RE, Adamson PC, Blayney SM et al.: A Phase I stduy of deciabine (DCT) in combination with doxorubicin (DOX) and cyclophosphamide (CTX) in the treatment of relapsed or refractory solid tumors: a Children's Oncology Group Study. American Society of Clinical Oncology. Orlando. FL, USA (2005).
-
(2005)
-
-
George, R.E.1
Adamson, P.C.2
Blayney, S.M.3
-
80
-
-
33750034664
-
Phase I trial of epothilone B analog BMS0247550 (ixabepilone) in children with refractory solid tumors
-
American Society of Clinical Oncology. Orlando, FL USA
-
Widemann BC, Goodspeed WJ, Goodwin A et al: Phase I trial of epothilone B analog BMS0247550 (ixabepilone) in children with refractory solid tumors. American Society of Clinical Oncology. Orlando, FL USA (2005).
-
(2005)
-
-
Widemann, B.C.1
Goodspeed, W.J.2
Goodwin, A.3
-
81
-
-
10744231592
-
Phase I trial of temozolomide and protracted irinotecan in pediatric patients with refractory solid tumors
-
Wagner LM, Crews KR, Iacono LC et al.: Phase I trial of temozolomide and protracted irinotecan in pediatric patients with refractory solid tumors. Clin. Cancer Res. 10, 840-848 (2004).
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 840-848
-
-
Wagner, L.M.1
Crews, K.R.2
Iacono, L.C.3
-
82
-
-
2342618217
-
Phase I trial of tirapazamine and cyclophosphamide in children with refractory solid tumors: A pediatric oncology group study
-
Aquino VM, Weltman SD, Winick NJ et al.: Phase I trial of tirapazamine and cyclophosphamide in children with refractory solid tumors: a pediatric oncology group study. J. Clin. Oncol. 22, 1413-1419 (2004)
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 1413-1419
-
-
Aquino, V.M.1
Weltman, S.D.2
Winick, N.J.3
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