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Volumn 34, Issue 16, 2006, Pages 4495-4505

CAG·CTG repeat instability in cultured human astrocytes

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

EID: 33750032103     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkl614     Document Type: Article
Times cited : (17)

References (49)
  • 1
    • 0029968460 scopus 로고    scopus 로고
    • Trinucleotide repeats in neurogenetic disorders
    • Paulson,H.L. and Fischbeck,K.H. (1996) Trinucleotide repeats in neurogenetic disorders. Annu. Rev. Neurosci., 19, 79-107.
    • (1996) Annu. Rev. Neurosci. , vol.19 , pp. 79-107
    • Paulson, H.L.1    Fischbeck, K.H.2
  • 2
    • 23044497731 scopus 로고    scopus 로고
    • Molecular models for repeat expansions
    • Mirkin,S.M. (2004) Molecular models for repeat expansions. Chemtracts-Biochem. Mol. Biol., 17, 639-662.
    • (2004) Chemtracts-Biochem. Mol. Biol. , vol.17 , pp. 639-662
    • Mirkin, S.M.1
  • 3
    • 25844438495 scopus 로고    scopus 로고
    • Repeat instability: Mechanisms of dynamic mutations
    • Pearson,C.E., Edamura,K.N. and Cleary,J.D. (2005) Repeat instability: mechanisms of dynamic mutations. Nature Rev. Genet., 6, 729-742.
    • (2005) Nature Rev. Genet. , vol.6 , pp. 729-742
    • Pearson, C.E.1    Edamura, K.N.2    Cleary, J.D.3
  • 4
    • 0035065524 scopus 로고    scopus 로고
    • Trinucleotide expansion in haploid germ cells by gap repair
    • Kovtun,I.V. and McMurray,C.T. (2001) Trinucleotide expansion in haploid germ cells by gap repair. Nature Genet., 27, 407-411.
    • (2001) Nature Genet. , vol.27 , pp. 407-411
    • Kovtun, I.V.1    McMurray, C.T.2
  • 5
    • 0035311021 scopus 로고    scopus 로고
    • Mouse tissue culture models of unstable triplet repeats: In vitro selection for larger alleles, mutational expansion bias and tissue specificity, but no association with cell division rates
    • Gomes-Pereira,M., Fortune,M.T. and Monckton,D.G. (2001) Mouse tissue culture models of unstable triplet repeats: In vitro selection for larger alleles, mutational expansion bias and tissue specificity, but no association with cell division rates. Hum. Mol. Genet., 10, 845-854.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 845-854
    • Gomes-Pereira, M.1    Fortune, M.T.2    Monckton, D.G.3
  • 6
    • 0034639711 scopus 로고    scopus 로고
    • Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instability
    • Fortune,M.T., Vassilopoulos,C., Coolbaugh,M.I., Siciliano,M.J. and Monckton,D.G. (2000) Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instability. Hum. Mol. Genet., 9, 439-445.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 439-445
    • Fortune, M.T.1    Vassilopoulos, C.2    Coolbaugh, M.I.3    Siciliano, M.J.4    Monckton, D.G.5
  • 7
    • 32244438870 scopus 로고    scopus 로고
    • Transcription promotes contraction of CAG repeat tracts in human cells
    • Lin,Y., Dion,V. and Wilson,J.H. (2006) Transcription promotes contraction of CAG repeat tracts in human cells. Nature Struct. Mol. Biol., 13, 179-180.
    • (2006) Nature Struct. Mol. Biol. , vol.13 , pp. 179-180
    • Lin, Y.1    Dion, V.2    Wilson, J.H.3
  • 8
    • 0042307369 scopus 로고    scopus 로고
    • Huntington disease expansion mutations in humans can occur before meiosis is completed
    • Yoon,S.-R., Dubeau,L., de Young,M., Wexler,N.S. and Arnheim,N. (2003) Huntington disease expansion mutations in humans can occur before meiosis is completed. Proc. Natl Acad. Sci. USA, 100, 8834-8838.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 8834-8838
    • Yoon, S.-R.1    Dubeau, L.2    de Young, M.3    Wexler, N.S.4    Arnheim, N.5
  • 9
    • 26944462396 scopus 로고    scopus 로고
    • Mechanistic features of CTG·CTG repeat contractions in cultured cells revealed by a novel genetic assay
    • Pelletier,R., Farrell,B.T., Miret,J.J. and Lahue,R.S. (2005) Mechanistic features of CTG·CTG repeat contractions in cultured cells revealed by a novel genetic assay. Nucleic Acids Res., 33, 5667-5676.
    • (2005) Nucleic Acids Res. , vol.33 , pp. 5667-5676
    • Pelletier, R.1    Farrell, B.T.2    Miret, J.J.3    Lahue, R.S.4
  • 10
    • 0037133931 scopus 로고    scopus 로고
    • In vitro (CTG) • (CAG) expansions and deletions by human cell extracts
    • Panigrahi,G.B., Cleary,J.D. and Pearson,C.E. (2002) In vitro (CTG) • (CAG) expansions and deletions by human cell extracts. J. Biol. Chem., 277, 13926-13934.
    • (2002) J. Biol. Chem. , vol.277 , pp. 13926-13934
    • Panigrahi, G.B.1    Cleary, J.D.2    Pearson, C.E.3
  • 11
    • 0036578758 scopus 로고    scopus 로고
    • Evidence of cis-acting factors in replication-mediated trinucleotide repeat instability in primate cells
    • Cleary,J.D., Nichol,K., Wang,Y.-H. and Pearson,C.E. (2002) Evidence of cis-acting factors in replication-mediated trinucleotide repeat instability in primate cells. Nature Genet., 31, 37-46.
    • (2002) Nature Genet. , vol.31 , pp. 37-46
    • Cleary, J.D.1    Nichol, K.2    Wang, Y.-H.3    Pearson, C.E.4
  • 12
    • 0242607211 scopus 로고    scopus 로고
    • Replication inhibitors modulate instability of an expanded trinucleotide repeat at the myotonic dystrophy type I disease locus in human cells
    • Yang,Z., Lau,R., Marcadier,J.L., Chitayat,D. and Pearson,C.E. (2003) Replication inhibitors modulate instability of an expanded trinucleotide repeat at the myotonic dystrophy type I disease locus in human cells. Am. J. Hum. Genet., 73, 1092-1105.
    • (2003) Am. J. Hum. Genet. , vol.73 , pp. 1092-1105
    • Yang, Z.1    Lau, R.2    Marcadier, J.L.3    Chitayat, D.4    Pearson, C.E.5
  • 13
    • 0029035379 scopus 로고
    • Expansion and deletion of CTG repeats from human disease genes are determined by the direction of replication in Escherichia coli
    • Kang,S., Jaworski,A., Ohshima,K. and Wells,R.D. (1995) Expansion and deletion of CTG repeats from human disease genes are determined by the direction of replication in Escherichia coli. Nature Genet., 10, 213-218.
    • (1995) Nature Genet. , vol.10 , pp. 213-218
    • Kang, S.1    Jaworski, A.2    Ohshima, K.3    Wells, R.D.4
  • 14
    • 0030725454 scopus 로고    scopus 로고
    • Trinucleotide repeats affect DNA replication in vivo
    • Samadashwily,G.M., Raca,G. and Mirkin,S.M. (1997) Trinucleotide repeats affect DNA replication in vivo. Nature Genet., 17, 298-304.
    • (1997) Nature Genet. , vol.17 , pp. 298-304
    • Samadashwily, G.M.1    Raca, G.2    Mirkin, S.M.3
  • 15
    • 0029958255 scopus 로고    scopus 로고
    • Orientation dependence of trinucleotide CAG repeat instability in Saccharomyces cerevisiae
    • Maurer,D.J., O'Callaghan,B.L. and Livingston,D.M. (1996) Orientation dependence of trinucleotide CAG repeat instability in Saccharomyces cerevisiae. Mol. Cell. Biol., 16, 6617-6622.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 6617-6622
    • Maurer, D.J.1    O'Callaghan, B.L.2    Livingston, D.M.3
  • 16
    • 0032514711 scopus 로고    scopus 로고
    • Orientation-dependent and sequence-specific expansions of CTG/CAG trinucleotide repeats in Saccharomyces cerevisiae
    • Miret,J.J., Pessoa-Brandao,L. and Lahue,R.S. (1998) Orientation-dependent and sequence-specific expansions of CTG/CAG trinucleotide repeats in Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA, 95, 12438-12443.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 12438-12443
    • Miret, J.J.1    Pessoa-Brandao, L.2    Lahue, R.S.3
  • 17
    • 0032907359 scopus 로고    scopus 로고
    • Transgenic mice harboring a full-length human mutant DRPLA gene exhibit age-dependent intergenerational and somatic instabilities of CAG repeats comparable with those in DRPLA patients
    • Sato,T., Oyake,M., Nakamura,K., Nakao,K., Fukusima,Y., Onodera,O., Igarashi,S., Takano,H., Kikugawa,K., Ishida,Y. et al. (1999) Transgenic mice harboring a full-length human mutant DRPLA gene exhibit age-dependent intergenerational and somatic instabilities of CAG repeats comparable with those in DRPLA patients. Hum. Mol. Genet., 8, 99-106.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 99-106
    • Sato, T.1    Oyake, M.2    Nakamura, K.3    Nakao, K.4    Fukusima, Y.5    Onodera, O.6    Igarashi, S.7    Takano, H.8    Kikugawa, K.9    Ishida, Y.10
  • 18
    • 0242524440 scopus 로고    scopus 로고
    • Regional differences of somatic CAG repeat instability do not account for selective neuronal vulnerability in a knock-in mouse model of SCA1
    • Watase,K., Venken,K.J.G., Sun,Y., Orr,H.T. and Zoghbi,H.Y. (2003) Regional differences of somatic CAG repeat instability do not account for selective neuronal vulnerability in a knock-in mouse model of SCA1. Hum. Mol. Genet., 12, 2789-2795.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 2789-2795
    • Watase, K.1    Venken, K.J.G.2    Sun, Y.3    Orr, H.T.4    Zoghbi, H.Y.5
  • 19
    • 0346752132 scopus 로고    scopus 로고
    • Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis
    • Kennedy,L., Evans,E., Chen,C.M., Craven,L., Detloff,P.J., Ennis,M. and Shelbourne,P.F. (2003) Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis. Hum. Mol. Genet., 12, 3359-3367.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 3359-3367
    • Kennedy, L.1    Evans, E.2    Chen, C.M.3    Craven, L.4    Detloff, P.J.5    Ennis, M.6    Shelbourne, P.F.7
  • 20
    • 0029035710 scopus 로고
    • Gametic and somatic tissue-specific heterogeneity of the expanded SCA 1 CAG repeat in spinocerebellar ataxia type 1
    • Chong,S.S., McCall,A.E., Cota,J., Subramony,S.H., Orr,H.T., Hughes,M.R. and Zoghbi,H.Y. (1995) Gametic and somatic tissue-specific heterogeneity of the expanded SCA 1 CAG repeat in spinocerebellar ataxia type 1. Nature Genet., 10, 344-350.
    • (1995) Nature Genet. , vol.10 , pp. 344-350
    • Chong, S.S.1    McCall, A.E.2    Cota, J.3    Subramony, S.H.4    Orr, H.T.5    Hughes, M.R.6    Zoghbi, H.Y.7
  • 21
    • 0029988921 scopus 로고    scopus 로고
    • Somatic mosaicism of expanded CAG repeats in brains of patients with dentatorubral-pallidoluysian atrophy: Cellular population-dependent dynamics of mitotic instability
    • Takano,H., Onodera,O., Takahashi,H., Igarashi,S., Yamada,M., Oyake,M., Ikeuchi,T., Koide,R., Tanaka,H., Iwabuchi,K. et al. (1996) Somatic mosaicism of expanded CAG repeats in brains of patients with dentatorubral-pallidoluysian atrophy: Cellular population-dependent dynamics of mitotic instability. Am. J. Hum. Genet., 58, 1212-1222.
    • (1996) Am. J. Hum. Genet. , vol.58 , pp. 1212-1222
    • Takano, H.1    Onodera, O.2    Takahashi, H.3    Igarashi, S.4    Yamada, M.5    Oyake, M.6    Ikeuchi, T.7    Koide, R.8    Tanaka, H.9    Iwabuchi, K.10
  • 22
    • 0030975726 scopus 로고    scopus 로고
    • Mosaicism of the CAG repeat in CNS tissue in relation to age at death in spinocerebellar ataxia type 1 and Machado-Joseph disease patients
    • Maciel,P., Lopes-Cendes,I., Kish,S., Sequeiros,J. and Rouleau,G.A. (1997) Mosaicism of the CAG repeat in CNS tissue in relation to age at death in spinocerebellar ataxia type 1 and Machado-Joseph disease patients. Am. J. Hum. Genet., 60, 993-996.
    • (1997) Am. J. Hum. Genet. , vol.60 , pp. 993-996
    • Maciel, P.1    Lopes-Cendes, I.2    Kish, S.3    Sequeiros, J.4    Rouleau, G.A.5
  • 23
    • 0034528090 scopus 로고    scopus 로고
    • Differential somatic CAG repeat instability in variable brain cell lineage in dentatorubral pallidoluysian atrophy (DRPLA): A laser-captured microdissection (LCM)-based analysis
    • Watanabe,H., Tanaka,F., Doyu,M., Riku,S., Yoshida,M., Hashizume,Y. and Sobue,G. (2000) Differential somatic CAG repeat instability in variable brain cell lineage in dentatorubral pallidoluysian atrophy (DRPLA): A laser-captured microdissection (LCM)-based analysis. Hum. Genet., 107, 452-457.
    • (2000) Hum. Genet. , vol.107 , pp. 452-457
    • Watanabe, H.1    Tanaka, F.2    Doyu, M.3    Riku, S.4    Yoshida, M.5    Hashizume, Y.6    Sobue, G.7
  • 24
    • 11144305102 scopus 로고    scopus 로고
    • Glial and neuronal expression of polyglutamine proteins induce behavioral changes and aggregate formation in Drosophila
    • Kretzschmar,D., Tschape,J., Bettencourt Da Cruz,A., Asan,E., Poeck,B., Strauss,R. and Pflugfelder,G.O. (2005) Glial and neuronal expression of polyglutamine proteins induce behavioral changes and aggregate formation in Drosophila. Glia, 49, 59-72.
    • (2005) Glia , vol.49 , pp. 59-72
    • Kretzschmar, D.1    Tschape, J.2    Bettencourt Da Cruz, A.3    Asan, E.4    Poeck, B.5    Strauss, R.6    Pflugfelder, G.O.7
  • 25
    • 29144460321 scopus 로고    scopus 로고
    • Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity
    • Shin,J.Y., Fang,Z.H., Yu,Z.X., Wang,C.E., Li,S.H. and Li,X.J. (2005) Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity. J. Cell. Biol., 171, 1001-1012.
    • (2005) J. Cell. Biol. , vol.171 , pp. 1001-1012
    • Shin, J.Y.1    Fang, Z.H.2    Yu, Z.X.3    Wang, C.E.4    Li, S.H.5    Li, X.J.6
  • 27
    • 0027982427 scopus 로고
    • Studying human mutations by sperm typing: Instability of CAG trinucleotide repeats in the human androgen receptor gene
    • Zhang,L., Leeflang,E.P., Yu,J. and Arnheim,N. (1994) Studying human mutations by sperm typing: Instability of CAG trinucleotide repeats in the human androgen receptor gene. Nature Genet., 7, 531-535.
    • (1994) Nature Genet. , vol.7 , pp. 531-535
    • Zhang, L.1    Leeflang, E.P.2    Yu, J.3    Arnheim, N.4
  • 28
    • 8544224974 scopus 로고    scopus 로고
    • Single sperm analysis of the CAG repeats in the gene for Machado-Joseph disease (MJD1): Evidence for non-Mendelian transmission of the MJD1 gene and for the effect of the intragenic CGG/GGG polymorphism on the intergenerational instability
    • Takiyama,Y., Sakoe,K., Soutome,M., Namekawa,M., Ogawa,T., Nakano,I., Igarashi,S., Oyake,M., Tanaka,H., Tsuji,S. et al. (1997) Single sperm analysis of the CAG repeats in the gene for Machado-Joseph disease (MJD1): Evidence for non-Mendelian transmission of the MJD1 gene and for the effect of the intragenic CGG/GGG polymorphism on the intergenerational instability. Hum. Mol. Genet., 6, 1063-1068.
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 1063-1068
    • Takiyama, Y.1    Sakoe, K.2    Soutome, M.3    Namekawa, M.4    Ogawa, T.5    Nakano, I.6    Igarashi, S.7    Oyake, M.8    Tanaka, H.9    Tsuji, S.10
  • 29
    • 0029897408 scopus 로고    scopus 로고
    • Analysis of germline variation at the FMR1 CGG repeat shows variation in the normal-premutated borderline range
    • Mornet,E., Chateau,C., Hirst,M.C., Thepot,F., Taillandier,A., Cibois,O. and Serre,J.-L. (1996) Analysis of germline variation at the FMR1 CGG repeat shows variation in the normal-premutated borderline range. Hum. Mol. Genet., 5, 821-825.
    • (1996) Hum. Mol. Genet. , vol.5 , pp. 821-825
    • Mornet, E.1    Chateau, C.2    Hirst, M.C.3    Thepot, F.4    Taillandier, A.5    Cibois, O.6    Serre, J.-L.7
  • 30
    • 0030795653 scopus 로고    scopus 로고
    • The effect of FMR1 CGG repeat interruptions on mutation frequency as measured by sperm typing
    • Kunst,C.B., Leeflang,E.P., Iber,J.C., Arnheim,N. and Warren,S.T. (1997) The effect of FMR1 CGG repeat interruptions on mutation frequency as measured by sperm typing. J. Med. Genet., 34, 627-631.
    • (1997) J. Med. Genet. , vol.34 , pp. 627-631
    • Kunst, C.B.1    Leeflang, E.P.2    Iber, J.C.3    Arnheim, N.4    Warren, S.T.5
  • 31
    • 11044230096 scopus 로고    scopus 로고
    • Somatic deletion events occur during early embryonic development and modify the extent of CAG expansion in subsequent generations
    • Kovtun,I.V., Thornhill,A.R. and McMurray,C.T. (2005) Somatic deletion events occur during early embryonic development and modify the extent of CAG expansion in subsequent generations. Hum. Mol. Genet., 13, 3057-3068.
    • (2005) Hum. Mol. Genet. , vol.13 , pp. 3057-3068
    • Kovtun, I.V.1    Thornhill, A.R.2    McMurray, C.T.3
  • 32
    • 4344636050 scopus 로고    scopus 로고
    • Yeast Srs2 DNA helicase selectively blocks expansions of trinucleotide repeats
    • Bhattacharyya,S. and Lahue,R.S. (2004) Yeast Srs2 DNA helicase selectively blocks expansions of trinucleotide repeats. Mol. Cell. Biol., 24, 7324-7330.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 7324-7330
    • Bhattacharyya, S.1    Lahue, R.S.2
  • 34
    • 0141680281 scopus 로고    scopus 로고
    • Derivation of a JC virus-resistant human glial cell line: Implications for the identification of host cell factors that determine viral tropism
    • Gee,G.V., Manley,K. and Atwood,W.J. (2003) Derivation of a JC virus-resistant human glial cell line: Implications for the identification of host cell factors that determine viral tropism. Virology, 314, 101-109.
    • (2003) Virology , vol.314 , pp. 101-109
    • Gee, G.V.1    Manley, K.2    Atwood, W.J.3
  • 35
    • 0024669291 scopus 로고
    • A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
    • Sikorski,R.S. and Hieter,P. (1989) A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics, 122, 19-27.
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.S.1    Hieter, P.2
  • 37
    • 0014202537 scopus 로고
    • Selective extraction of polyoma DNA from infected mouse cell cultures
    • Hirt,B. (1967) Selective extraction of polyoma DNA from infected mouse cell cultures. J. Mol. Biol., 26, 365-369.
    • (1967) J. Mol. Biol. , vol.26 , pp. 365-369
    • Hirt, B.1
  • 38
    • 0026562884 scopus 로고
    • Improved method for high efficiency transformation of intact yeast cells
    • Gietz,D., St Jean,A., Woods,R.A. and Schiestl,R.H. (1992) Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res., 20, 1425.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 1425
    • Gietz, D.1    St Jean, A.2    Woods, R.A.3    Schiestl, R.H.4
  • 39
    • 15244353338 scopus 로고    scopus 로고
    • Opposing roles of ERK and p38 MAP kinases in FGF2-induced astroglial process extension
    • Heffron,D.S. and Mandell,J.W. (2005) Opposing roles of ERK and p38 MAP kinases in FGF2-induced astroglial process extension. Mol. Cell. Neurosci., 28, 779-790.
    • (2005) Mol. Cell. Neurosci. , vol.28 , pp. 779-790
    • Heffron, D.S.1    Mandell, J.W.2
  • 40
    • 0027215019 scopus 로고
    • Frameshift fidelity during replication of double-stranded DNA in HeLa cell extracts
    • Roberts,J.D., Nguyen,D. and Kunkel,T.A. (1993) Frameshift fidelity during replication of double-stranded DNA in HeLa cell extracts. Biochemistry, 32, 4083-4089.
    • (1993) Biochemistry , vol.32 , pp. 4083-4089
    • Roberts, J.D.1    Nguyen, D.2    Kunkel, T.A.3
  • 41
    • 0025127308 scopus 로고
    • Nucleosome assembly in mammalian cell extracts before and after DNA replication
    • Gruss,C., Gutierrez,C., Burhans,W.C., DePamphilis,M.L., Koller,T. and Sogo,J.M. (1990) Nucleosome assembly in mammalian cell extracts before and after DNA replication. EMBO J., 9, 2911-2922.
    • (1990) EMBO J. , vol.9 , pp. 2911-2922
    • Gruss, C.1    Gutierrez, C.2    Burhans, W.C.3    DePamphilis, M.L.4    Koller, T.5    Sogo, J.M.6
  • 42
    • 0029053371 scopus 로고
    • Trinucleotide repeats that expand in human disease form hairpin structure in vitro
    • Gacy,A.M., Goellner,G., Juranic,N., Macura,S. and McMurray,C.T. (1995) Trinucleotide repeats that expand in human disease form hairpin structure in vitro. Cell, 81, 533-540.
    • (1995) Cell , vol.81 , pp. 533-540
    • Gacy, A.M.1    Goellner, G.2    Juranic, N.3    Macura, S.4    McMurray, C.T.5
  • 43
    • 0029883805 scopus 로고    scopus 로고
    • Alternative structures in duplex DNA formed within the trinucleotide repeats of the myotonic dystrophy and fragile X loci
    • Pearson,C.E. and Sinden,R.R. (1996) Alternative structures in duplex DNA formed within the trinucleotide repeats of the myotonic dystrophy and fragile X loci. Biochemistry, 35, 5041-5053.
    • (1996) Biochemistry , vol.35 , pp. 5041-5053
    • Pearson, C.E.1    Sinden, R.R.2
  • 44
    • 0030737538 scopus 로고    scopus 로고
    • Trinucleotide repeats associated with human disease
    • Mitas,M. (1997) Trinucleotide repeats associated with human disease. Nucleic Acids Res., 25, 2245-2253.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2245-2253
    • Mitas, M.1
  • 45
    • 0022369964 scopus 로고
    • Neuronal nuclear membrane indentation and astrocyte/neuron ratio in Huntington's disease. A quantitative electron microscopic study
    • Roos,R.A., Bots,G.T. and Hermans,J. (1985) Neuronal nuclear membrane indentation and astrocyte/neuron ratio in Huntington's disease. A quantitative electron microscopic study. J. Hirnforsch., 26, 689-693.
    • (1985) J. Hirnforsch. , vol.26 , pp. 689-693
    • Roos, R.A.1    Bots, G.T.2    Hermans, J.3
  • 46
    • 0033129397 scopus 로고    scopus 로고
    • Analysis of the CAG repeat number in a patient with Huntington's disease
    • Kono,Y., Agawa,Y., Watanabe,Y., Ohama,E., Nanba,E. and Nakashima,K. (1999) Analysis of the CAG repeat number in a patient with Huntington's disease. Intern. Med., 38, 407-411.
    • (1999) Intern. Med. , vol.38 , pp. 407-411
    • Kono, Y.1    Agawa, Y.2    Watanabe, Y.3    Ohama, E.4    Nanba, E.5    Nakashima, K.6
  • 47
    • 0030895078 scopus 로고    scopus 로고
    • Stability of a CTG/CAG trinucleotide repeat in yeast is dependent on its orientation in the genome
    • Freudenreich,C.H., Stavenhagen,J.B. and Zakian,V.A. (1997) Stability of a CTG/CAG trinucleotide repeat in yeast is dependent on its orientation in the genome. Mol. Cell. Biol., 17, 2090-2098.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2090-2098
    • Freudenreich, C.H.1    Stavenhagen, J.B.2    Zakian, V.A.3
  • 48
    • 2542560500 scopus 로고    scopus 로고
    • DNA elements important for CTG repeat thresholds in Saccharomyces cerevisiae
    • Dixon,M.J. and Lahue,R.S. (2004) DNA elements important for CTG repeat thresholds in Saccharomyces cerevisiae. Nucleic Acids Res., 32, 1289-1297.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 1289-1297
    • Dixon, M.J.1    Lahue, R.S.2
  • 49
    • 0027495515 scopus 로고
    • Evidence for a mechanism predisposing to intergenerational CAG repeat instability in spinocerebellar ataxia type I
    • Chung,M.-Y., Ranum,L.P.W., Duvick,L.A., Servadio,A., Zoghbi,H.Y. and Orr,H.T. (1993) Evidence for a mechanism predisposing to intergenerational CAG repeat instability in spinocerebellar ataxia type I. Nature Genet., 5, 254-258.
    • (1993) Nature Genet. , vol.5 , pp. 254-258
    • Chung, M.-Y.1    Ranum, L.P.W.2    Duvick, L.A.3    Servadio, A.4    Zoghbi, H.Y.5    Orr, H.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.