Characterization of a novel cAMP-binding, cAMP-specific cyclic nucleotide phosphodiesterase (TcrPDEB1) from Trypanosoma cruzi

Biochemical Journal

Volumn 399, Issue 2, 2006, Pages 305-314

  Díaz Benjumea, Rocío ^a   Laxman, Sunil ^b   Hinds, Thomas R ^b   Beavo, Joseph A ^b   Rascón, Ana ^a  

^a FACULTAD DE CIENCIAS   (Venezuela)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Anabaena adenylate cyclases and Escherichia coli FhlA domain (GAF domain); cAMP; cGMP specific and stimulated phosphodiesterases; Phosphodiesterase (PDE); Trypanosoma cruzi

Indexed keywords

ANABAENA ADENYLATE CYCLASES AND ESCHERICHIA COLI FHLA DOMAIN (GAF DOMAIN); CAMP; CGMP-SPECIFIC AND -STIMULATED PHOSPHODIESTERASES; PHOSPHODIESTERASE (PDE); TRYPANOSOMA CRUZI;

BIOCHEMISTRY; CALORIMETRY; CATALYSIS; ENZYME INHIBITION; FLUORESCENCE; PHOSPHORUS COMPOUNDS;

ENZYMES;

2' O(N METHYLANTHRANILOYL)ADENOSINE 3',5' CYCLIC MONOPHOSPHATE; 9 (2 HYDROXY 3 NONYL)ADENINE; ADENYLATE CYCLASE; CYCLIC AMP; CYCLIC AMP DERIVATIVE; CYCLIC GMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE B1; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE B2; DIPYRIDAMOLE; ENOXIMONE; ISOBUTYLMETHYLXANTHINE; PAPAVERINE; PENTOXIFYLLINE; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; ROLIPRAM; UNCLASSIFIED DRUG; ZAPRINAST;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CALORIMETRY; CATALYSIS; CONTROLLED STUDY; DRUG INHIBITION; ENZYME INHIBITION; HUMAN; HUMAN CELL; KINETOPLAST; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; AMINO ACID SEQUENCE; ANIMALS; ANTHRANILIC ACIDS; CATALYTIC DOMAIN; CELLS, CULTURED; CYCLIC AMP; CYCLIC GMP; GENE AMPLIFICATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; HYDROLYSIS; KINETICS; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; PARASITES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; TRYPANOSOMA CRUZI;

ANABAENA; ESCHERICHIA COLI; MAMMALIA; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI; TRYPANOSOMATIDAE;

EID: 33750005401     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20060757     Document Type: Article

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