DNA mismatch repair mediates protection from mutagenesis induced by short-wave ultraviolet light

DNA Repair

Volumn 5, Issue 11, 2006, Pages 1364-1372

  Borgdorff, Viola ^a   Pauw, Bea ^a   van Hees Stuivenberg, Sandrine ^a   de Wind, Niels ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

DNA mismatch repair; Embryonic stem cells; Mutagenesis; UVC light

Indexed keywords

HETERODIMER; PROTEIN MSH2; PROTEIN MSH6; PYRIMIDINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; EMBRYONIC STEM CELL; GENE MUTATION; INDUCED MUTATION; MISMATCH REPAIR; MOUSE; MUTAGENESIS; MUTATION RATE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; ULTRAVIOLET C RADIATION; WILD TYPE;

ANIMALS; APOPTOSIS; CELL LINE; DNA MISMATCH REPAIR; DNA-BINDING PROTEINS; EMBRYONIC STEM CELLS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MICE; MODELS, GENETIC; MUTAGENESIS; MUTS HOMOLOG 2 PROTEIN; POINT MUTATION; ULTRAVIOLET RAYS;

EID: 33749990624     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2006.06.005     Document Type: Article

References (41)

1. Kunkel T.A., and Erie D.A. DNA mismatch repair. Annu. Rev. Biochem. 74 (2005) 681-710
2. Peltomaki P. Lynch syndrome genes. Fam. Cancer 4 (2005) 227-232
3. Kat A., Thilly W.G., Fang W.H., Longley M.J., Li G.M., and Modrich P. An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 6424-6428
4. Swann P.F., Waters T.R., Moulton D.C., Xu Y.Z., Zheng Q., Edwards M., and Mace R. Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine. Science 273 (1996) 1109-1111
5. DeWeese T.L., Shipman J.M., Larrier N.A., Buckley N.M., Kidd L.R., Groopman J.D., Cutler R.G., te Riele H., and Nelson W.G. Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiation. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 11915-11920
6. Russo M.T., Blasi M.F., Chiera F., Fortini P., Degan P., Macpherson P., Furuichi M., Nakabeppu Y., Karran P., Aquilina G., and Bignami M. The oxidized deoxynucleoside triphosphate pool is a significant contributor to genetic instability in mismatch repair-deficient cells. Mol. Cell. Biol. 24 (2004) 465-474
7. Glaab W.E., and Skopek T.R. Cytotoxic and mutagenic response of mismatch repair-defective human cancer cells exposed to a food-associated heterocyclic amine. Carcinogenesis 20 (1999) 391-394
8. Glaab W.E., Kort K.L., and Skopek T.R. Specificity of mutations induced by the food-associated heterocyclic amine 2-amino-1-methyl-6-phenylimidazo-[4,5-b]-pyridine in colon cancer cell lines defective in mismatch repair. Cancer Res. 60 (2000) 4921-4925
9. Cadet J., Sage E., and Douki T. Ultraviolet radiation-mediated damage to cellular DNA. Mutat. Res. 571 (2005) 3-17
10. Nara K., Nagashima F., and Yasui A. Highly elevated ultraviolet-induced mutation frequency in isolated Chinese hamster cell lines defective in nucleotide excision repair and mismatch repair proteins. Cancer Res. 61 (2001) 50-52
11. de Laat W.L., Jaspers N.G., and Hoeijmakers J.H. Molecular mechanism of nucleotide excision repair. Genes Dev. 13 (1999) 768-785
12. Shin-Darlak C.Y., Skinner A.M., and Turker M.S. A role for Pms2 in the prevention of tandem CC → TT substitutions induced by ultraviolet radiation and oxidative stress. DNA Repair (Amst.) 4 (2005) 51-57
13. Vrieling H., Venema J., van Rooyen M.L., van Hoffen A., Menichini P., Zdzienicka M.Z., Simons J.W., Mullenders L.H., and van Zeeland A.A. Strand specificity for UV-induced DNA repair and mutations in the Chinese hamster HPRT gene. Nucl. Acids Res. 19 (1991) 2411-2415
14. Hawk J.D., Stefaniovic L., Boyer J.C., Petes T.C., and Farber R.A. Variation in efficiency of DNA mismatch repair at different sites in the yeast genome. Proc. Natl. Acad. Sci. U.S.A. 105 (2005) 8639-8643
15. Reya T., Morrison S.J., Clarke M.F., and Weissman I.L. Stem cells, cancer, and cancer stem cells. Nature 414 (2001) 105-111
16. Smalley M., and Ashworth A. Stem cells and breast cancer: a field in transit. Nat. Rev. Cancer 3 (2003) 832-844
17. de Wind N., Dekker M., Berns A., Radman M., and te Riele H. Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer. Cell 82 (1995) 321-330
18. de Wind N., Dekker M., Claij N., Jansen L., van Klink Y., Radman M., Riggins G., van der Valk M., van't Wout K., and te Riele H. HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions. Nat. Genet. 23 (1999) 359-362
19. Borgdorff V., van Hees-Stuivenberg S., Meijers C.M., and de Wind N. Spontaneous and mutagen-induced loss of DNA mismatch repair in Msh2-heterozygous mammalian cells. Mutat. Res. 574 (2005) 50-57
20. Peters A.C., Young L.C., Maeda T., Tron V.A., and Andrew S.E. Mammalian DNA mismatch repair protects cells from UVB-induced DNA damage by facilitating apoptosis and p53 activation. DNA Repair (Amst.) 2 (2003) 427-435
21. Young L.C., Peters A.C., Maeda T., Edelmann W., Kucherlapati R., Andrew S.E., and Tron V.A. DNA mismatch repair protein Msh6 is required for optimal levels of ultraviolet-B-induced apoptosis in primary mouse fibroblasts. J. Invest. Dermatol. 121 (2003) 876-880
22. Mu D., Tursun M., Duckett D.R., Drummond J.T., Modrich P., and Sancar A. Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systems. Mol. Cell. Biol. 17 (1997) 760-769
23. Wang H., Lawrence C.W., Li G.M., and Hays J.B. Specific binding of human MSH2.MSH6 mismatch-repair protein heterodimers to DNA incorporating thymine- or uracil-containing UV light photoproducts opposite mismatched bases. J. Biol. Chem. 274 (1999) 16894-16900
24. Hoffman P.D., Wang H., Lawrence C.W., Iwai S., Hanaoka F., and Hays J.B. Binding of MutS mismatch repair protein to DNA containing UV photoproducts, "mismatched" opposite Watson-Crick and novel nucleotides, in different DNA sequence contexts. DNA Repair (Amst.) 4 (2005) 983-993
25. van Oosten M., Stout G.J., Backendorf C., Rebel H., de Wind N., Darroudi F., van Kranen H.J., de Gruijl F.R., and Mullenders L.H. Mismatch repair protein Msh2 contributes to UVB-induced cell cycle arrest in epidermal and cultured mouse keratinocytes. DNA Repair (Amst.) 4 (2005) 81-89
26. Jansen J.G., Tsaalbi-Shtylik A., Langerak P., Calleja F., Meijers C.M., Jacobs H., and de Wind N. The BRCT domain of mammalian Rev1 is involved in regulating DNA translesion synthesis. Nucl. Acids Res. 33 (2005) 356-365
27. Schultheis P.J., and Lingrel J.B. Substitution of transmembrane residues with hydrogen-bonding potential in the alpha subunit of Na,K-ATPase reveals alterations in ouabain sensitivity. Biochemistry 32 (1993) 544-550
28. Pfeifer G.P., You Y.H., and Besaratinia A. Mutations induced by ultraviolet light. Mutat. Res. 571 (2005) 19-31
29. Vrieling H., Van Rooijen M.L., Groen N.A., Zdzienicka M.Z., Simons J.W., Lohman P.H., and van Zeeland A.A. DNA strand specificity for UV-induced mutations in mammalian cells. Mol. Cell. Biol. 9 (1989) 1277-1283
30. Hanawalt P. Revisiting the Rodent Repairadox. Environ. Mol. Mutgen. 38 (2001) 89-96
31. van Sloun P.P.H., Jansen J.G., Weeda G., Mullenders L.H.F., van Zeeland A.A., Lohman P.H.M., and Vrieling H. The role of nucleotide excision repair in protecting embryonic stem cells from genotoxic effects of UV-induced DNA damage. Nucl. Acids Res. 27 (1999) 3276-3282
32. Tu Y., Damman R., and Pfeifer G.P. Sequence and time-dependent deamination of cytosine bases in UVB-induced cyclobutane pyrimidine dimers in vivo. J. Mol. Biol. 284 (1998) 297-311
33. Lee D.-H., and Pfeifer G. Deamination of 5-methylcytosines within cyclobutane pyrimidine dimers is an important component of UVB mutagenesis. J. Biol. Chem. 278 (2003) 10214-10321
34. Lehmann A.R. Replication of damaged DNA by translesion synthesis in human cells. FEBS Lett. 579 (2005) 873-876
35. Person S., McCloskey J.A., Snipes W., and Bockradt R.C. Ultraviolet mutagenesis and its repair in an Escherichia coli strain containing a nonsense codon. Genetics 78 (1974) 1035-1049
36. Liu H., Hewitt S.R., and Hays J.B. Antagonism of ultraviolet-light mutagenesis by the methyl-directed mismatch-repair system of Escherichia coli. Genetics 154 (2000) 503-512
37. Wang H., Hoffman P.D., Lawrence C., and Hays J.B. Testing excision models for responses of mismatch-repair systems to UV photoproducts in DNA. Environ. Mol. Mutagen. (2006) 296-306
38. Schaaper R.M. Base selection, proofreading, and mismatch repair during DNA replication in Escherichia coli. J. Biol. Chem. 268 (1993) 23762-23765
39. Meira L.B., Cheo D.L., Reis A.M., Claij N., Burns D.K., te Riele H., and Friedberg E.C. Mice defective in the mismatch repair gene Msh2 show increased predisposition to UVB radiation-induced skin cancer. DNA Repair (Amst.) 1 (2002) 929-934
40. Yoshino M., Nakatsu Y., te Riele H., Hirota S., Kitamura K., and Tanaka K. Additive roles of XPA and MSH2 genes in UVB-induced skin tumorigenesis in mice. DNA Repair (Amst.) 1 (2002) 935-940
41. Lucci-Cordisco E., Zito I., Gensini F., and Genuardi M. Hereditary nonpolyposis colorectal cancer and related conditions. Am. J. Med. Genet. 122 (2003) 325-334